Male infertility workshop
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"Serono Meeting for Assisted Reproductive Technology (SMART VI)", Cape Town, South Africa, April 2010
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Male infertility workshop
- 1. SMART VI Workshop Cape Town, South Africa 2010 Novel Concepts in Male Infertility
- 4. Varicocele: surgery Esteves, Technique Testicular Artery preserved Hydrocele (%) Failure (%) Potential morbidity Retroperitoneal No 7 15-45 No Inguinal conventional No 3-39 5-25 No Laparoscopic Yes 10 5-15 Yes Embolization Yes 0 15-25 Yes Microsurgical Yes 0 0.5-3 No
- 5. Take home messages: Varicocele (1) Esteves,
- 7. O-254: ICSI IN INFERTILE MEN WITH TREATED AND UNTREATED VARICOCELE Esteves, Oliveira & Bertolla – Brazil; ASRM 2009 Results: Clinical Pregnancy Frequency of Clinical Pregnancy *Pearson’s Chi-square test Logistic Regression of Group 1 on Group 2 with Clinical Pregnancy as Dependent Variable Group 1 (N=80; Treated) Group 2 (N=162; Untreated) P-value * Clinical Pregnancy N (%) 48 (60.0) 73 (45.0) 0.03 Group 1 P-value Odds-ratio 95% CI for OR Lower Upper Clinical Pregnancy 0.04 1.69 1.00 2.84
- 9. Spermatogenic cycle length J Urol 2006; 175:242-246 Esteves,
- 14. I. Successful sperm retrieval by TESE Microdissection TESE Schlegel 1999 27 63 41 .01 Amer 2000 100 47 30 <.05 Okada 2002 50 45 17 <.05 Esteves 2003 13 61 38 <.05 Year N Microsurgery Conventional P II. Testicular tissue removed (mg) Schlegel 1999 27 9.4 722 .01 Amer 2000 100 4.6 54 <.05 Year N Microsurgery Conventional P
- 18. Esteves,
Notas do Editor
- 242 infertile men were included, divided in 2 groups: In group 1, Eighty men had a prior successful microsurgical subinguinal varicocelectomy (all of them performed by the same urologist); and in Group 2, 162 men had any grade of clinical varicocele at the time of ICSI. For group 1, semen analysis results were compared before and after surgery. Clinical pregnancy rates were compared between groups, and a logistic regression analysis was performed to verify if surgical correction of the varicoceles increased the odds of obtaining a clinical pregnancy or decreased the odds of miscarriage occurence.
- Clinical pregnancy rates after ICSI were significantly higher (60%) in the treated group. Moreover, the chance of obtaining a clinical pregnancy was increased by 69% if the varicocele had been treated before ICSI, as shown by the logistic regression.