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Chest X-ray Evaluation of Cardiac
            Patients




                 Dr Awadhesh Kumar Sharma,
Wilhelm Conrad Roentgen (1845 - 1923)

"I did not think I investigated...It seemed at first
a new kind of invisible light. It was clearly
something new something unrecorded...There is
much to do, and I am busy, very busy"
                     Wilhelm Conrad Röntgen
(First observer of X-rays made on 8 Nov 1895)
INTRODUCTION
   The discovery of X-rays by W.C.Roentgen,the
    german physicist on November 8,1895 ,was a
    crucially important landmark in the
    advancement of medical knowledge.
   The cardiopulmonary images help us to
    understand the anatomy, physiology and
    pathophysiology of the heart and blood vessels
    because of the excellent contrast between the
    lungs filled with air and the opaque silhouette
    of the heart and vessels filled with blood.
   With careful evaluation, it yields a large amount of anatomic
    and physiologic information, but it is difficult and sometimes
    even impossible to extract the information that it contains.
   The major variables that determine what can be learned from
    the chest x-ray include the technical factors (miliamperage
    [mA], kilo voltage [kV], exposure duration) used in obtaining
    the radiographs, patient specific factors (e.g., body habitus,
    age, physiologic status, ability to stand and to take and hold a
    deep breath), and the training, experience, and focus of the
    interpreter.
   The aims of my todays seminar are to review how chest
    radiographs are obtained, present a basic approach to their
    interpretation, and discuss and illustrate common and
    characteristic findings relevant to cardiovascular disease in
    adults.
Technical Considerations
   The usual chest radiograph consists of a frontal and a lateral
    view. The frontal view is a postero anterior (PA) view, with
    the patient standing with the chest toward the recording
    medium and the back to the x-ray tube. The lateral view is also
    taken with the patient standing, with the left side toward the
    film.
   For both, the x-ray tube is positioned at a distance of 6 feet
    from the film. This is termed a 6-foot SID (source-image
    distance).
   At 6 feet distance the focal length of X-rays gives maximum
    resolution with less irradiation. The beam is near parallel
    without divergence and distortions.
   X-rays are blocked from the film or other recording medium to
    varying degrees by various structures, leading to shades of
    gray that allow discrimination between the heart, which is
    fluid-filled and relatively impervious to x-rays, and the air-
    filled lung parenchyma, which blocks few x-rays.
   The exposure that the patient receives is a function of the
    strength and duration of the current applied to the x-ray tube
    (or, more precisely and accurately, of the number, strength and
    duration of the x-ray photons produced—the mA, kV, and
    milliseconds), size of the focal spot, distance from the tube to
    the patient, and degree to which the x-rays are blocked and
    scattered within the patient.
   Most patient exposure is not a result of the x-rays that
    penetrate, but rather those that interact with tissues and are
    slowed and changed, and in the process deposit residual
    energy in tissue. This process is what is broadly referred to as
    scatter.
   Patients who are very thin will require an inherently lower x-
    ray dose to achieve diagnostically satisfactory deposition of x-
    ray photons on an imaging medium, and will have less energy
    deposition within the body. In patients who are obese, a higher
    x-ray dose will be necessary to penetrate the patient and
    produce a diagnostic exposure. The increased soft tissue in
    these patients also causes more dispersion of the x-ray beam
    and results in a higher dose.
   There are several additional practical considerations that relate
    to the physics of chest radiographs. The standard chest
    radiograph is obtained with deep inspiration and the patient
    facing the film. If patients are unable to stand, chest
    radiographs are generally obtained with the patient's chest
    toward the tube and the back toward the film, the antero-
    posterior (AP) position.
   With the standard PA view, the heart appears smaller and its
    size and contour are more accurately depicted than on an AP
    view, because the heart is closer to the recording medium.
   With AP views, as with portable films, there is resultant
    greater divergence of x-rays because the heart lies relatively
    anteriorly (and so is farther from the film) .
X-ray film is close to the heart in PA view,hence further magnification is avoided.In AP view ,the film is
over the posterior chest and away from the heart,resulting in 5-10% magnification of heart shadow hence
                                          apparent cardiomegaly.
   X-ray chest PA view if taken in
    expiration, gives a false impression of
    cardiomegaly, widening of aorta and
    prominent pulmonary arteries .This is the
    importance of taking X-ray chest held in
    deep inspiration- the criteria for it is
    being able to see ten posterior ribs and/or
    six anterior ribs.
X-ray chest PA view
showing effects of
expiration. There is
pseudo cardiomegaly
and aorta becomes
prominent.
Properly exposed chest film PA view
         held in inspiration
Portable radiographs
   Portable radiographs are invariably taken as AP
    views and the SID is less than 6 feet, of necessity,
    because of the nature of the portable x-ray machine
    and also because of the usual position of the patient,
    sitting or lying in a bed. Most portable x-ray units do
    not have generators sufficiently strong to be able to
    produce x-rays that will penetrate a patient
    adequately and expose the film from 6 feet. Space
    constraints and the patient's position are additional
    hurdles.
   For all these reasons, the inherent resolution is poorer with
    portable radiographs, making them less accurate and useful.
    Also because of the lower available energy with portable x-ray
    units and the longer exposure time necessary to compensate,
    radiation exposure to the patient is greater than with a standard
    PA film.
   Portable films are most useful for answering relatively simple
    mechanical questions, such as whether the pacemaker or
    automated implantable cardioverter-defibrillator (ICD) is
    properly positioned , whether the endotracheal tube is in the
    correct location, and whether the mediastinum is midline.
    They are generally not good at providing physiologic or
    complex anatomic information.
Portable X-ray machine
Image Recording and Radiation
               Exposure
   Until the turn of the last century, all chest radiographs
    were recorded on high-resolution x-ray film. With
    optimal technique and a cooperative patient who can
    hold a deep inspiration, the result is a study that
    clearly and accurately depicts very small structures,
    such as the contour of small pulmonary arteries.
   This has changed as the digital age has come to
    imaging. With the advent of digital radiography
    (DR), a filmless form of radiography, chest
    radiographs are increasingly stored on digital media.
   DR, is the direct recording of images by digital
    means, without analog-to-digital conversion. The
    most common is flat plate technology for reasons of
    resolution, usefulness and, in the long term, cost. It
    involves the use of an image-sensing plate that
    directly converts the incident photons into a digital
    signal.
   DR is truly “filmless”; and the classic chest
    radiograph relies on film that is exposed and
    developed.
Radiation Hazards
   The radiation exposure to the patient should always be kept in
    mind when any x-ray study is ordered or performed. The
    complexity of diagnostic radiation in the general population
    limits obtaining clear answers. However, a real concern is that
    ionizing radiation at cumulative diagnostic doses may be
    teratogenic and may, over decades, cause cancers.
   The radiation necessary for PA and lateral chest films is
    usually minimal in terms of radiation effects, in both the dose
    of a single study (generally <1 mSv) and the cumulative dose
    of repeated chest x-rays.
   In pregnant women and children, radiation exposure is always
    a concern because of the long latency period for radiation-
    induced cancer.
   The contribution from conventional imaging
    procedures, such as chest x-rays, is small, but the
    precise relationships between individual exposures
    and cumulative effect are not known.
   Despite this, and despite the lack of clarity of the
    relationship between diagnostic level radiation and
    cancer, it is always wise to limit the amount of
    radiation as much as possible. Consequently, each
    chest film should be ordered with care.
   Whether the dose is actually decreased with digital
    imaging remains an open question, because digital
    systems continue to evolve rapidly.
Normal Chest Radiograph
   Interpreting standard PA and lateral chest radiographs is a daunting task.
    The amount of information present is huge, and there are countless relevant
    variables. It is imperative to have a systematic and standardized approach,
    based first on an assessment of anatomy, then of physiology, and finally of
    pathology.
   Any approach must be based on an understanding of what is normal and
    must include an evaluation of the soft tissues, bones and joints, pleura,
    lungs and major airways, pulmonary vascularity, mediastinum and its
    contents, and heart and its chambers specifically, as well as the areas seen
    below the diaphragm and above the thorax.
   In the standard PA chest study, the overall heart diameter is normally less
    than half the transverse diameter of the thorax . The heart overlies the
    thoracic spine, roughly 75% to the left of the spine and 25% to the right.
    The mediastinum is narrow superiorly, and normally the descending aorta
    can be defined from the arch to the dome of the diaphragm, on the left. The
    pulmonary hila are seen below the aortic arch, slightly higher on the left
    than the right.
Normal chest X-ray
   On the lateral film , the left main pulmonary artery can be seen coursing
    superiorly and posteriorly compared with the right. On both frontal and
    lateral views, the ascending aorta (aortic root) is normally obscured by the
    main pulmonary artery and both atria. The location of the pulmonary
    outflow tract is usually clear on the lateral film.
   On the normal chest film, it is not usually possible to define individual
    cardiac chambers. It is imperative, however, to know their normal position
    and to examine the film to determine whether the size and location of each
    chamber and the great vessels are within the normal range.
   On the PA view, the right contour of the mediastinum contains the right
    atrium and the ascending aorta and superior vena cava (SVC). If the
    azygous vein is enlarged, secondary to right heart failure or SVC
    obstruction , it may also be visible. The right ventricle, as is clear from
    cross-sectional imaging , is located partially overlying the left ventricle on
    both frontal and lateral views.
   The left atrium is located just inferior to the left pulmonary hilum. In
    normal individuals, there is a concavity at this level, which is the location
    of the left atrial appendage. The atrium constitutes the upper portion of the
    posterior contour of the heart on the lateral film but cannot normally be
    differentiated from the left ventricle.
   The left ventricle constitutes the prominent, rounded apex of the heart on
    the frontal view and the sloping inferior portion of the mediastinum on the
    lateral view .
   The apex is often not clearly delineated for a reason related to x-ray
    attenuation. The heart is distinguishable from the lungs because it contains
    water density blood rather than air. Because blood attenuates x-rays to a
    greater extent than air, the heart appears relatively white (although less so
    than calcium-containing bones) and the lungs relatively black (less so than
    the edges of the film, where there is only air and no interposed tissue).
Chest X-ray PA view: Normal. Structures
forming right and left borders of the heart
Chest X-ray PA view
Structures forming anterior and posterior
borders of the heart
   A fat pad of varying thickness surrounds the apex of the heart . Fat has a
    density greater than that of air and marginally less than that of blood. As it
    covers the ventricular apex, the fat pad is relatively thick and dense. As it
    thins out toward the left lateral chest wall, it is progressively less dense;
    hence, the hazy, poorly marginated appearance of the apex. Similarly, a fat
    pad may be seen on the lateral chest film as a wedge-shaped density
    overlying the anterior aspect of the left ventricle.
   The pericardial sac cannot normally be defined . The borders of the cardiac
    silhouette are normally moderately but not completely sharp in contour.
    Even though the exposure time for a chest x-ray is very short (less than
    100 milliseconds), there is usually sufficient cardiac motion to cause minor
    haziness of the silhouette. If a portion of the heart border does not move, as
    in the case of a left ventricular aneurysm, the border may be unusually
    sharp .
   The aortic arch, however, is usually visible, as the aorta courses posteriorly
    and is surrounded by air. Most of the descending aorta is also visible. The
    position and the size of each can be easily evaluated using the frontal and
    lateral views.
Lungs and Pulmonary Vasculature
   Lung size varies as a function of inspiratory effort, age, body habitus,
    water content, and intrinsic pathologic processes. For example, because
    lung distensibility decreases with age, the lungs normally appear subtly but
    progressively smaller as patients age, even with maximal inspiratory effort.
    As lung size decreases, the heart appears relatively slightly larger, although
    in adults the heart does not exceed half the transverse diameter of the chest
    in a good-quality PA film unless there is true cardiomegaly.
   Also, with increasing left ventricular dysfunction, interstitial fluid in the
    lungs increases and lung compliance, and therefore expansion as seen on a
    chest x-ray, decreases. With the presence of chronic obstructive pulmonary
    disease, with or without bullae, the lungs appear larger and blacker, the
    diaphragms may appear flattened, and the relative heart size, even in the
    presence of heart failure, decreases. The heart often appears small or
    normal in size, even in the presence of cardiac dysfunction .
Barrel shaped chest
in a patient with
emphysema
   In normal subjects, pulmonary vascularity has a predictable pattern.
    Pulmonary arteries are usually easily visible centrally in the hila and
    progressively less so more peripherally. Centrally, the main right and left
    pulmonary arteries are difficult to quantify unless they are grossly
    enlarged, because they lie within the mediastinum .
   If the lung is thought of in three zones, the major arteries are central; the
    clearly distinguishable midsized pulmonary arteries (third and fourth order
    branches) are in the middle zone, and the small arteries and arterioles that
    are normally below the limit of resolution are in the outer zone.
   The visible small and midsized arteries (midzone) have sharp, clearly
    definable margins. As noted, this is because of the sharp border between
    water density and air density structures. In the standard, standing frontal
    (PA) chest film, the arteries in the lower zone are larger than those in the
    upper zone, at an equal distance from the hila. This is because of the effect
    of gravity on the normal, low-pressure lung circulation. That is, gravity
    leads to slightly greater intravascular volume at the lung bases than in the
    upper zones.
   This effect of gravity on the distribution of
    normal intravascular lung volume is reflected
    in a normal perfusion lung scan. Because the
    radionuclide is generally administered with the
    patient supine, there is a greater concentration
    posteriorly than anteriorly, as confirmed in the
    count rates. If the patient is sitting or standing
    when the radionuclide is injected, the count
    rate is greater at the lung base than at the
    apices.
Evaluating the Chest Radiograph in
          Heart Disease
   There is no single best way to read a chest film. A systematic approach to
    the evaluation of a chest radiograph is imperative to distinguish normal
    from abnormal and to define the underlying pathology and
    pathophysiology.
   The first step is to define which type of film is being evaluated—PA and
    lateral, PA alone, or AP view (either portable or one obtained in the AP
    view because the patient is unable to stand).
   The next step is to determine whether prior films are available for
    comparison. Many abnormalities are put into appropriate perspective by
    determining whether they are new. Common examples are a prominent
    aortic arch, visible major fissure related to prior inflammatory process, or
    widened superior mediastinum related to aortic ectasia , substernal thyroid,
    or enlarged azygous vein .
   Any system should incorporate a routine that includes a deliberate attempt
    to look at areas that are easily ignored. These include the thoracic spine,
    neck (for masses and tracheal position), costophrenic angles, lung apices,
    retrocardiac space, and retrosternal space. Looking at these areas enables
    definition of mediastinal position and cardiac and aortic situs and the
    presence of pleural effusions, scarring, or diaphragmatic elevation.
   It is logical to evaluate the lung fields next. This should involve a careful
    search for infiltrates or masses, even when the primary concern is
    cardiovascular abnormalities. The logic is that many people with coronary
    artery disease have a history of tobacco abuse and are thus at increased risk
    for lung malignancies.
   Cardiovascular disease states cause various and complex changes in the
    appearance of the chest radiograph. The overall size of the cardiac
    silhouette, its position, and the location of the ascending and descending
    aorta must be specifically evaluated.
Cervical rib on the right side
   Dextrocardia and a right descending aorta are rare, particularly
    in adults, but are easy to check for and are important to
    recognize because of their association with congenital cardiac
    and abdominal situs abnormalities. It is also important to look
    at the site and position of the stomach. This information can be
    used to differentiate between a high diaphragm and a pleural
    effusion .
   Cardiomegaly, accurately judged by the heart diameter
    exceeding half the diameter of the thorax on a PA film, is a
    common but nonspecific finding.It is probably most often seen
    as a result of ischemic cardiomyopathy following one or more
    myocardial infarctions.
CARDIOMEGALY IN X-RAY CHEST(PA VIEW)
   Trans cardiac diameter is
    measured as follows-
        Mark a mid-vertical line
    along the spinous process.
        Draw a horizontal line from
    the vertical line to the maximum
    convexity in the right cardiac
    border.
        Draw another horizontal line
    from the vertical line to the
    maximum convexity in the left
    cardiac border
     Line A+B=Transcardiac
    diameter
      Transthoracic diameter at the
    level of inner border of ninth rib.
   Cardiothoracic ratio=TCD/TTD
   Normally cardiothoracic ratio is 33%-
    50%(0.33-0.50).
   Any increase in transcardiac diameter more
    then 2 cm,is significant if earlier X-rays are
    available for comparison.
   In old age and emphysema, transcardiac
    diameter of 15 cm or more is taken as
    cardiomegaly irrespective of CT ratio.
Assessment of pulmonary
      vasculature
   Evaluation of the pulmonary vascular pattern is difficult and imprecise but
    very important. As noted, the pattern varies with the patient's position
    (erect versus supine) and is altered substantially by underlying pulmonary
    disease. It is best to define pulmonary vascularity by looking at the middle
    zone of the lungs (i.e., the third of the lungs between the hilar region and
    peripheral region laterally) and comparing a region in the upper portion of
    the lungs with a region in the lower portion, at equal distances from the
    hilum.
   Vessels should be larger in the lower lung but sharply marginated in the
    upper and lower zones. In normal individuals, the vessels taper and
    bifurcate and are difficult to define in the outer third of the lung. They
    normally become too small to be seen near the pleura
   Two distinct patterns of abnormality are recognizable. When pulmonary
    arterial flow is increased, as in patients with a high-output state (e.g.,
    pregnancy, severe anemia as in sickle cell disease, hyperthyroidism) or
    left-to-right shunt, the pulmonary vessels are seen more prominently than
    usual in the periphery of the lung.
   They are uniformly enlarged and can be traced almost to the pleura, but
    their margins remain clear. In contrast, in patients with elevated pulmonary
    venous pressure, the vessel borders become hazy, the lower zone vessels
    constrict and the upper zone vessels enlarge, and vessels become visible
    farther toward the pleura, in the outer third of the lungs
Larry Elliots grading of Pulmonary Venous
               Hypertension
Grade-1
pulmonary venous
hypertension-
The upper lobe
veins becomes
more prominent
than the lower
lobe veins-
cephalisation
   Grade-2 pulmonary venous
    hypertension-
   Kerleys lines are due to
    interlobular septal thickening
    due to lymphatic and venous
    drainage.
   Kerleys A lines-Horizontal
    linear shadows towards the
    hilum.
    Kerleys B lines-Horizontal and
    linear shadows towards the
    costophrenic angle.
   Kerleys C lines-Crisscross
    between A and B.
Chest X-ray PA view of 40
year old male with grade-II
pulmonary venous
hypertension-
Top panel shows typical
features of pulmonary
venous hypertension with
Kerley's lines and
interstitial oedema.
Bottom panel shows X-
rays of the same patient 4
hours after treatment with
diuretics.
Grade –III
pulmonary venous
hypertension
Alveolar edema,
manifesting as
bilateral diffuse patchy
cotton wool opacities
in the lung
parenchyma.
Grade IV
pulmonary
venous
hypertension
-results in
bilateral miliary
mottling
-hemosiderosis
-calcification
-irreversible
Assessment of cardiac chambers
Right Atrium
   Right atrial enlargement is essentially never isolated
    except in the presence of congenital tricuspid atresia
    or Ebstein anomaly. Both are rarely encountered,
    even in the pediatric age group.
   The right atrium may dilate in the presence of
    pulmonary hypertension or tricuspid regurgitation,
    but right ventricular dilation usually predominates
    and prevents definition of the atrium.
   The right atrial contour blends with that of the SVC,
    right main pulmonary artery, and right ventricle.
Radiological features S/O Right
      atrial enlargement in PA view
   Right cardiac border becomes more convex and
    elongated. It forms more then 50% of right cardiac
    border.
   Distance from mid-vertical line to the maximum
    convexity in the right border is more then 5cm in
    adults and more then 4cm in children which results in
    cardiomegaly.
   Right atrial border extends beyond three intercostal
    spaces.
   Dilation of superior vena cava.
Right atrial enlargement in LAO
                   view
   Normally in LAO view, upper half of anterior
    cardiac border is formed by right atrium and
    lower half by right ventricle.
   When right atrium enlarges the upper anterior
    cardiac border becomes squared giving a box
    like appearance.
   LAO is the best view to visualise right atrial
    enlargement.
Right atrial
enlargement in a
patient with
rheumatic mitral
stenosis. There is
left atrial
enlargement and
mitralisation too,
of heart.
Right Ventricle
   The classic signs of right ventricular enlargement are a boot-shaped heart
    and filling in of the retrosternal air space.The former is caused by
    transverse displacement of the apex of the right ventricle as it dilates. In
    adults, it is rare for the right ventricle to dilate without left ventricular
    dilation, so this boot shape is not often obvious. It is most commonly seen
    as an isolated finding in congenital heart disease, typically in tetralogy of
    Fallot. As the right ventricle dilates, it expands superiorly as well as
    laterally and posteriorly, explaining the well-marginated increase in density
    in the retrosternal airspace.
   The classic teaching is that in a lateral chest radiograph in normal patients,
    the soft tissue density is confined to less than one third of the distance from
    the suprasternal notch to the tip of the xephoid. If the soft tissue fills in by
    more than one third, in the absence of other explanations, it is a reliable
    indication of right ventricular enlargement.
Right ventricular
enlargement
PA view-Rounded
and elevated apex
from the left dome
of the diaphragm
Right lateral view-
Obliteration of
retrosternal space
Chest radiographs of a 59-year-old woman with a history of rheumatic heart disease and
mitral stenosis. a, PA view demonstrates enlarged cardiac silhouette, with suggestion of a
double density seen through the heart (left atrial enlargement), prominent convexity of the
left atrial appendage (small arrow), and slightly elevated cardiac apex (large arrow),
suggestive of right ventricular (rather than left ventricular) enlargement. there is significant
elevation of the pulmonary venous pressures.
B, The lateral view confirms marked right ventricular (arrow) and left atrial (small arrows)
enlargement. note filling in of the retrosternal airspace. la = left atrium; lv = left ventricle.
Left Atrium
   Several classic signs define left atrial enlargement-
    The first is dilation of the left atrial appendage, seen as a focal convexity
    where there is normally a concavity between the left main pulmonary
    artery and left border of the left ventricle on the frontal view .
    Second, because of its location, as the left atrium enlarges, it elevates the
    left main stem bronchus. In so doing, it widens the angle of the
    carina,normal being 45-75 degrees.
   Third, with marked left atrial enlargement, a double density can be seen on
    the frontal view because the left atrium projects laterally toward the right
    and posteriorly, and the discrete outline of the blood-filled left atrium is
    surrounded by air-filled lung .
   Finally, on the lateral film, left atrial enlargement appears as a focal,
    posteriorly directed bulge .
Chest X-ray PA view
 of two patients with
varying degree of left
atrial enlargement in
  rheumatic mitral
        stenosis
Left Ventricle
   Left ventricular enlargement is characterized by a prominent, downwardly directed
    contour of the apex, as distinguished from the transverse displacement seen with
    right ventricular enlargement.
    On the PA film, the overall cardiac contour is also usually enlarged, although this
    is a nonspecific finding.
   It may also be seen inferiorly, pushing the gastric bubble . Such left ventricular
    enlargement is an illustration of findings that lie outside the usual confines of the
    chest and another example of the value of looking at the entire chest radiograph.
    Focal left ventricular enlargement in adults is most commonly seen in the presence
    of aortic insufficiency (with aortic root dilation; or mitral regurgitation (with left
    atrial dilation.
   In contrast, because aortic stenosis is characterized by left ventricular hypertrophy
    rather than dilation, the left ventricle is dilated on the chest film only when aortic
    stenosis is accompanied by left ventricular failure.
Chest radiographs of a 63-year-old man with chronic aortic regurgitation. A, PA view shows downward
 displacement of the apex (arrow), suggestive of left ventricular enlargement. There is prominence and
enlargement of the ascending aorta, creating a convex right border of the mediastinum. B, Lateral view
shows prominent left ventricular enlargement (arrowheads). The aortic root is markedly enlarged in the
   retrosternal airspace but is separate from the sternum (in contrast to findings in right ventricular
                                             enlargement).
Assessment of great vessels
Pulmonary Arteries
   The main pulmonary artery can appear abnormal in many clinical settings.
    In the presence of pulmonic stenosis, the main pulmonary artery and left
    pulmonary artery dilate . This dilation is thought to be caused by the jet
    effect on the vessel wall of the blood flow through the stenotic valve,
    coupled with the anatomy. That is, the main pulmonary artery continues
    straight into the left main pulmonary artery but the right comes off at a
    fairly sharp angle and is not generally affected by the jet from the stenotic
    valve. This enlargement can be seen with a prominent left hilum on the
    frontal view and a prominent pulmonary outflow tract on the lateral view.
    It is important to remember that the pulmonic valve lies more superiorly in
    the outflow tract and more anteriorly than the aortic valve .
Chest radiographs of a 56-year-old asymptomatic woman with
  incidentally discovered pulmonic stenosis. A, PA view shows marked
 enlargement of the main pulmonary trunk extending into the left main
 pulmonary artery (arrow). B, Lateral view confirms prominence of the
pulmonary outflow tract and main and left pulmonary arteries (arrows).
Aorta
   The most commonly seen abnormality of the aorta is dilation,
    and the way the aorta dilates is a function of the underlying
    pathology . It is often possible to define the pathology by a
    combination of the pattern of dilation and associated cardiac
    abnormalities.
   On the frontal chest radiograph, aortic dilation appears as a
    prominence to the right of the middle mediastinum . There is
    also a prominence in the anterior mediastinum on the lateral
    view, behind and superior to the pulmonary outflow tract.
    Dilation of the aortic root is seen in the presence of aortic
    valve disease (both stenosis and regurgitation) but more
    frequently has other causes, such as long-term, poorly
    controlled systemic hypertension or generalized
    atherosclerosis with ectasia.
Chest radiographs of a 65-year-old woman with severe aortic stenosis. A, Frontal
view shows a prominent aortic root, to the right of the midline (arrowheads). Note
 absence of cardiomegaly and presence of normal pulmonary vascular pattern. B,
   Lateral view demonstrates calcification of the aortic valve leaflets (arrows),
  suggestive of a bicuspid valve. There is a prominent, mildly dilated aortic root
                                   (arrowheads).
Pleura and Pericardium
   The pleura and pericardium also require systematic evaluation. The
    pericardium is rarely distinctly definable on plain films of the chest.There
    are two situations, however, in which it can be seen; in the presence of a
    large pericardial effusion, the visceral and parietal pericardium separate.
    Because there is a fat pad associated with each, it is sometimes possible to
    make out two parallel lucent lines (i.e., fat) on the lateral film, usually in
    the area of the cardiac apex, with density (fluid) between them. CMRI,
    echocardiography, and CT, however, are all far more reliable for defining a
    pericardial effusion
   Nonetheless, if the cardiac silhouette is enlarged on the chest radiograph, it
    is important to look for specific explanations. Although cardiac dilation
    and valvular disease are more common causes, the presence of an
    unsuspected effusion is worth considering. Typically, the cardiac silhouette
    has a water bottle shape in the presence of a pericardial effusion, but this
    shape is not in itself diagnostic.
Pericardial effusion
   Cardiomegaly
   Cardio phrenic angles
    become more and more
    acute.
   Narrow vascular pedicle
   Marked change in
    cardiac silhouette in
    decubitus position is
    very diagnostic.
Pleural and pericardial calcification
   Pleural and pericardial calcification can occur, but are often not obvious .
    Pericardial calcification is associated with a history of pericarditis.
    Although there are multiple causes, tuberculosis and various viruses are the
    most common. Such calcification is usually thin and linear and follows the
    contour of the pericardium. Because the calcification is thin, it is often seen
    only on one view.
    Myocardial calcification secondary to a large myocardial infarction with
    transmural necrosis is rare but can generally be distinguished from
    pericardial calcification. It tends to appear thicker, more focal, and less
    consistent with the outer contour of the heart.
   Pleural calcification is easily distinguishable from pericardial calcification
    and is essentially pathognomonic for asbestos exposure. It is associated
    with a high risk of malignant mesothelioma but is not diagnostic of this
    type of tumor.
Chest radiographs of a 45-year-old man with calcific pericarditis.
 A, PA view is essentially normal. B, Lateral view demonstrates
    thin, irregular calcification of pericardium around the left
                        ventricular contour.
Chest radiograph showing marked pericardial calcification in a
            patient with constrictive pericarditis.
Cardiac valves calcification
Calcified cardiac valves
Chest PA view
Aortic valve will be at the level of
T6-T7 overlying the midline area.
Mitral valve will be at T8 level away
from the midline in the paravertebral
region.
Lateral view
Aortic calcification is above an
imaginary line from left bronchus to
RV apex and mitral calcification is
below the line.
Specific clinical situation
Rheumatic valvular heart diseases
   Rheumatic Mitral Stenosis
   X-ray chest PA view
   The typical mitralisation.
   Less prominent aortic knuckle.
   Obliteration of pulmonary bay due to prominent main
    and left pulmonary arteries.
   Prominent left atrial appendage.
   Straightening of convex contour of left ventricular
    border due to hypoplasia and hypovolumia.
Top panel shows
mitralisation.
Bottom panel
shows gross
enlargement of
main pulmonary
artery, left atria and
left atrial
appendage dilation
and right
ventricular
enlargement.
Mitral stenosis
Mitral regurgitation
   Left atrial
    enlargement
   Left
    ventricular
    enlargement
   Right atrial
    enlargement
MS+MR
Aortic valvular
stenosis
Left
ventricular
hypertrophy
and left
ventricular
dilation
Aortic valvular
regurgitation
Left
ventricular
dilation
Left atrial
enlargement
Prosthetic valves
Congenital heart diseases-Acyanotic
 Without a shunt
 Pulmonary valvular stenosis

 The radiological features are-

 Pulmonary oligaemia

 Post-stenotic dilatation of main pulmonary
  artery
 Right ventricular enlargement

 Right atrial enlargrment
Valvular pulmonary stenosis
Primary pulmonary
              hypertension
 X-ray chest PA view
 Moderate to marked enlargement of main
  pulmonary artery and its proximal branches.
 Peripheral pulmonary arteries are diminished
  and pruned resulting in clear peripheral lung
  fields.
 Absence of pulmonary venous hypertension.

 Small and inconspicuous ascending aorta

 Right ventricular and right atrial enlargement

 Absent left atrial enlargement
Primary pulmonary hypertension
Congenital heart diseases-Acyanotic
 With a shunt
 Shunt at atrial level

 Shunt at ventricular level

 Shunt at aorto pulmonary level

 Pulmonary plethora is common in all left to
  right shunts.
Atrial septal defect
 Ostium secundum ASD
 Enlargement of RV,RA and LA.

 Left ventricle is hypovolaemic and
  hypoplastic.
 Right pulmonary artery is more prominent
  than left pulmonary artery giving the
  radiological sign of jug-handle appearance.
 Ostium primum ASD

Left ventricular enlargement in addition to the
  radiological features of OS –ASD.
Ostium secundum ASD
Ostium primum ASD
VSD
   All four chambers are
    involved.
   The ascending aorta is
    inconspicuous.
   Both pulmonary arteries
    are equally prominent.
Patent Ductus Arteriosus
   All the four chambers are
    involved.
   Prominent ascending aorta.
   There may be speck of
    calcium when PDA is
    calcified.It is comma shaped
    between aortic knuckle and
    main pulmonary artery and
    is known as Cap of Zin.
   Both pulmonary arteries are
    equally dilated.
Congenital cyanotic heart diseases
   Increased pulmonary
    arterial blood flow
   Complete transposition
    of great arteries(d-TGA)
   Absent thymic shadow
   Narrow vascular pedicle
   Increased CT ratio with
    egg lying on its side
    appearance
   Pulmonary plethora
Truncus Arteriosus
   All four chambers are
    dilated with pulmonary
    plethora.
   In one – third of cases
    right aortic arch is
    present.
TAPVC
   Supracardiac type is the
    commonest and will
    have a distinctive figure
    of 8 or snowman
    silhouette or cottage
    loaf.The upper portion
    of figure of 8 is formed
    by the dilated left
    vertical vein and right
    superior vena cava.The
    lower portion consists
    of dilated right atrium
    and right ventricle.
Decreased pulmonary arterial blood flow
   Tetralogy of Fallot
   No cardiomegaly
   Uplifted apex-boot shaped or
    coeur en sabot appearance
   Pulmonary oligaemia
   Dilated ascending aorta with right
    aortic arch in 25% of cases
   Bilateral reticular formation due
    to bronchopulmonary collaterals
   Unilateral rib notching after BT
    shunt
Ebstein anomaly of the tricuspid valve
   Cardiomegaly with
    dilated right atrium and
    right ventricular
    infundibulum accounts
    for the box like
    silhouette with normal
    or decreased pulmonary
    blood flow,resembling
    pericardial effusion.
Coarction of aorta
   Three sign on chest X-ray
   E sign or reverse 3 sign in barium
    swallow
   Rib notching of 3rd to 8th posterior
    ribs along its lower border usually
    after the age of 9 years
Cardiac malposition
Situs solitus   Situs inversus totalis
Implantable Devices and Other Postsurgical
                    Findings
   A final important and broad area concerns the chest radiograph following
    surgery or other procedures. In these situations, it is crucial to recognize
    devices that have been implanted and changes that may occur. Among the
    most common are various valve prostheses, pacemakers and ICDs, intra-
    aortic counterpulsation balloons , and ventricular assist devices . There are
    also clear changes that occur after surgery, such as the presence of clips on
    the side branches of saphenous veins used for coronary artery bypass
    grafting and retrosternal blurring and effusions
   Some of these findings may be temporary, such as lines and tubes
    associated with surgery and effusions. Pacemakers and ICDs present
    specific questions . The first is whether the leads are intact and the second
    is the position of the tips. Although course and tip position are generally
    confirmed fluoroscopically at the time of placement, malposition can
    occur. If there are two leads, the tips should generally be in the
    anterolateral wall of the right atrium and apex of the right ventricle.
   If the leads are not positioned in this way, the reasons
    should be carefully determined. That is, are they
    positioned because of error or anatomic variants (e.g.,
    a persistent left SVC that empties into the coronary
    sinus and then the right atrium or because the lead
    belongs in the coronary sinus. Additionally, the
    position of the wires and of valve prostheses can help
    in the definition of specific chamber enlargement
   AV sequential
    pacemaker in right infra
    clavicular subcutaneous
    pocket. J shaped atrial
    lead is seen in right
    atrial appendage.Tip of
    ventricular lead is in
    right ventricular apex.
   Biventricular pacing.
    Atrial lead is in right
    atrium; right ventricular
    lead is in RV apex, left
    ventricular lead is
    introduced through
    coronary sinus to pace
    left ventricular
    epicardium.
Conclusion
   Chest radiographs provide a wealth of physiologic and anatomic
    information. As such, they play a central role in the evaluation and
    management of patients with a wide variety of cardiovascular and other
    disorders.
   The radiation dose inherent in obtaining x-rays should always be
    considered.
   Portable chest films should be used as infrequently as possible because the
    information they provide is limited and may even be misleading (e.g., in
    defining cardiomegaly or in ruling out a pneumothorax or effusion).
   Standard 6-foot frontal and lateral chest x-rays, on the other hand, are
    almost always of value. Whether recorded conventionally or digitally, if
    they are evaluated carefully using a systematic approach and, whenever
    possible, compared with prior chest radiographs, it is hard to overstate their
    importance.
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  • 1. Chest X-ray Evaluation of Cardiac Patients Dr Awadhesh Kumar Sharma,
  • 2. Wilhelm Conrad Roentgen (1845 - 1923) "I did not think I investigated...It seemed at first a new kind of invisible light. It was clearly something new something unrecorded...There is much to do, and I am busy, very busy" Wilhelm Conrad Röntgen (First observer of X-rays made on 8 Nov 1895)
  • 3. INTRODUCTION  The discovery of X-rays by W.C.Roentgen,the german physicist on November 8,1895 ,was a crucially important landmark in the advancement of medical knowledge.  The cardiopulmonary images help us to understand the anatomy, physiology and pathophysiology of the heart and blood vessels because of the excellent contrast between the lungs filled with air and the opaque silhouette of the heart and vessels filled with blood.
  • 4. With careful evaluation, it yields a large amount of anatomic and physiologic information, but it is difficult and sometimes even impossible to extract the information that it contains.  The major variables that determine what can be learned from the chest x-ray include the technical factors (miliamperage [mA], kilo voltage [kV], exposure duration) used in obtaining the radiographs, patient specific factors (e.g., body habitus, age, physiologic status, ability to stand and to take and hold a deep breath), and the training, experience, and focus of the interpreter.  The aims of my todays seminar are to review how chest radiographs are obtained, present a basic approach to their interpretation, and discuss and illustrate common and characteristic findings relevant to cardiovascular disease in adults.
  • 5. Technical Considerations  The usual chest radiograph consists of a frontal and a lateral view. The frontal view is a postero anterior (PA) view, with the patient standing with the chest toward the recording medium and the back to the x-ray tube. The lateral view is also taken with the patient standing, with the left side toward the film.  For both, the x-ray tube is positioned at a distance of 6 feet from the film. This is termed a 6-foot SID (source-image distance).  At 6 feet distance the focal length of X-rays gives maximum resolution with less irradiation. The beam is near parallel without divergence and distortions.
  • 6. X-rays are blocked from the film or other recording medium to varying degrees by various structures, leading to shades of gray that allow discrimination between the heart, which is fluid-filled and relatively impervious to x-rays, and the air- filled lung parenchyma, which blocks few x-rays.  The exposure that the patient receives is a function of the strength and duration of the current applied to the x-ray tube (or, more precisely and accurately, of the number, strength and duration of the x-ray photons produced—the mA, kV, and milliseconds), size of the focal spot, distance from the tube to the patient, and degree to which the x-rays are blocked and scattered within the patient.
  • 7. Most patient exposure is not a result of the x-rays that penetrate, but rather those that interact with tissues and are slowed and changed, and in the process deposit residual energy in tissue. This process is what is broadly referred to as scatter.  Patients who are very thin will require an inherently lower x- ray dose to achieve diagnostically satisfactory deposition of x- ray photons on an imaging medium, and will have less energy deposition within the body. In patients who are obese, a higher x-ray dose will be necessary to penetrate the patient and produce a diagnostic exposure. The increased soft tissue in these patients also causes more dispersion of the x-ray beam and results in a higher dose.
  • 8. There are several additional practical considerations that relate to the physics of chest radiographs. The standard chest radiograph is obtained with deep inspiration and the patient facing the film. If patients are unable to stand, chest radiographs are generally obtained with the patient's chest toward the tube and the back toward the film, the antero- posterior (AP) position.  With the standard PA view, the heart appears smaller and its size and contour are more accurately depicted than on an AP view, because the heart is closer to the recording medium.  With AP views, as with portable films, there is resultant greater divergence of x-rays because the heart lies relatively anteriorly (and so is farther from the film) .
  • 9. X-ray film is close to the heart in PA view,hence further magnification is avoided.In AP view ,the film is over the posterior chest and away from the heart,resulting in 5-10% magnification of heart shadow hence apparent cardiomegaly.
  • 10. X-ray chest PA view if taken in expiration, gives a false impression of cardiomegaly, widening of aorta and prominent pulmonary arteries .This is the importance of taking X-ray chest held in deep inspiration- the criteria for it is being able to see ten posterior ribs and/or six anterior ribs.
  • 11. X-ray chest PA view showing effects of expiration. There is pseudo cardiomegaly and aorta becomes prominent.
  • 12. Properly exposed chest film PA view held in inspiration
  • 13. Portable radiographs  Portable radiographs are invariably taken as AP views and the SID is less than 6 feet, of necessity, because of the nature of the portable x-ray machine and also because of the usual position of the patient, sitting or lying in a bed. Most portable x-ray units do not have generators sufficiently strong to be able to produce x-rays that will penetrate a patient adequately and expose the film from 6 feet. Space constraints and the patient's position are additional hurdles.
  • 14. For all these reasons, the inherent resolution is poorer with portable radiographs, making them less accurate and useful. Also because of the lower available energy with portable x-ray units and the longer exposure time necessary to compensate, radiation exposure to the patient is greater than with a standard PA film.  Portable films are most useful for answering relatively simple mechanical questions, such as whether the pacemaker or automated implantable cardioverter-defibrillator (ICD) is properly positioned , whether the endotracheal tube is in the correct location, and whether the mediastinum is midline. They are generally not good at providing physiologic or complex anatomic information.
  • 16. Image Recording and Radiation Exposure  Until the turn of the last century, all chest radiographs were recorded on high-resolution x-ray film. With optimal technique and a cooperative patient who can hold a deep inspiration, the result is a study that clearly and accurately depicts very small structures, such as the contour of small pulmonary arteries.  This has changed as the digital age has come to imaging. With the advent of digital radiography (DR), a filmless form of radiography, chest radiographs are increasingly stored on digital media.
  • 17. DR, is the direct recording of images by digital means, without analog-to-digital conversion. The most common is flat plate technology for reasons of resolution, usefulness and, in the long term, cost. It involves the use of an image-sensing plate that directly converts the incident photons into a digital signal.  DR is truly “filmless”; and the classic chest radiograph relies on film that is exposed and developed.
  • 18. Radiation Hazards  The radiation exposure to the patient should always be kept in mind when any x-ray study is ordered or performed. The complexity of diagnostic radiation in the general population limits obtaining clear answers. However, a real concern is that ionizing radiation at cumulative diagnostic doses may be teratogenic and may, over decades, cause cancers.  The radiation necessary for PA and lateral chest films is usually minimal in terms of radiation effects, in both the dose of a single study (generally <1 mSv) and the cumulative dose of repeated chest x-rays.  In pregnant women and children, radiation exposure is always a concern because of the long latency period for radiation- induced cancer.
  • 19. The contribution from conventional imaging procedures, such as chest x-rays, is small, but the precise relationships between individual exposures and cumulative effect are not known.  Despite this, and despite the lack of clarity of the relationship between diagnostic level radiation and cancer, it is always wise to limit the amount of radiation as much as possible. Consequently, each chest film should be ordered with care.  Whether the dose is actually decreased with digital imaging remains an open question, because digital systems continue to evolve rapidly.
  • 20. Normal Chest Radiograph  Interpreting standard PA and lateral chest radiographs is a daunting task. The amount of information present is huge, and there are countless relevant variables. It is imperative to have a systematic and standardized approach, based first on an assessment of anatomy, then of physiology, and finally of pathology.  Any approach must be based on an understanding of what is normal and must include an evaluation of the soft tissues, bones and joints, pleura, lungs and major airways, pulmonary vascularity, mediastinum and its contents, and heart and its chambers specifically, as well as the areas seen below the diaphragm and above the thorax.  In the standard PA chest study, the overall heart diameter is normally less than half the transverse diameter of the thorax . The heart overlies the thoracic spine, roughly 75% to the left of the spine and 25% to the right. The mediastinum is narrow superiorly, and normally the descending aorta can be defined from the arch to the dome of the diaphragm, on the left. The pulmonary hila are seen below the aortic arch, slightly higher on the left than the right.
  • 22. On the lateral film , the left main pulmonary artery can be seen coursing superiorly and posteriorly compared with the right. On both frontal and lateral views, the ascending aorta (aortic root) is normally obscured by the main pulmonary artery and both atria. The location of the pulmonary outflow tract is usually clear on the lateral film.  On the normal chest film, it is not usually possible to define individual cardiac chambers. It is imperative, however, to know their normal position and to examine the film to determine whether the size and location of each chamber and the great vessels are within the normal range.  On the PA view, the right contour of the mediastinum contains the right atrium and the ascending aorta and superior vena cava (SVC). If the azygous vein is enlarged, secondary to right heart failure or SVC obstruction , it may also be visible. The right ventricle, as is clear from cross-sectional imaging , is located partially overlying the left ventricle on both frontal and lateral views.
  • 23. The left atrium is located just inferior to the left pulmonary hilum. In normal individuals, there is a concavity at this level, which is the location of the left atrial appendage. The atrium constitutes the upper portion of the posterior contour of the heart on the lateral film but cannot normally be differentiated from the left ventricle.  The left ventricle constitutes the prominent, rounded apex of the heart on the frontal view and the sloping inferior portion of the mediastinum on the lateral view .  The apex is often not clearly delineated for a reason related to x-ray attenuation. The heart is distinguishable from the lungs because it contains water density blood rather than air. Because blood attenuates x-rays to a greater extent than air, the heart appears relatively white (although less so than calcium-containing bones) and the lungs relatively black (less so than the edges of the film, where there is only air and no interposed tissue).
  • 24. Chest X-ray PA view: Normal. Structures forming right and left borders of the heart
  • 25. Chest X-ray PA view Structures forming anterior and posterior borders of the heart
  • 26. A fat pad of varying thickness surrounds the apex of the heart . Fat has a density greater than that of air and marginally less than that of blood. As it covers the ventricular apex, the fat pad is relatively thick and dense. As it thins out toward the left lateral chest wall, it is progressively less dense; hence, the hazy, poorly marginated appearance of the apex. Similarly, a fat pad may be seen on the lateral chest film as a wedge-shaped density overlying the anterior aspect of the left ventricle.  The pericardial sac cannot normally be defined . The borders of the cardiac silhouette are normally moderately but not completely sharp in contour. Even though the exposure time for a chest x-ray is very short (less than 100 milliseconds), there is usually sufficient cardiac motion to cause minor haziness of the silhouette. If a portion of the heart border does not move, as in the case of a left ventricular aneurysm, the border may be unusually sharp .  The aortic arch, however, is usually visible, as the aorta courses posteriorly and is surrounded by air. Most of the descending aorta is also visible. The position and the size of each can be easily evaluated using the frontal and lateral views.
  • 27.
  • 28. Lungs and Pulmonary Vasculature  Lung size varies as a function of inspiratory effort, age, body habitus, water content, and intrinsic pathologic processes. For example, because lung distensibility decreases with age, the lungs normally appear subtly but progressively smaller as patients age, even with maximal inspiratory effort. As lung size decreases, the heart appears relatively slightly larger, although in adults the heart does not exceed half the transverse diameter of the chest in a good-quality PA film unless there is true cardiomegaly.  Also, with increasing left ventricular dysfunction, interstitial fluid in the lungs increases and lung compliance, and therefore expansion as seen on a chest x-ray, decreases. With the presence of chronic obstructive pulmonary disease, with or without bullae, the lungs appear larger and blacker, the diaphragms may appear flattened, and the relative heart size, even in the presence of heart failure, decreases. The heart often appears small or normal in size, even in the presence of cardiac dysfunction .
  • 29. Barrel shaped chest in a patient with emphysema
  • 30. In normal subjects, pulmonary vascularity has a predictable pattern. Pulmonary arteries are usually easily visible centrally in the hila and progressively less so more peripherally. Centrally, the main right and left pulmonary arteries are difficult to quantify unless they are grossly enlarged, because they lie within the mediastinum .  If the lung is thought of in three zones, the major arteries are central; the clearly distinguishable midsized pulmonary arteries (third and fourth order branches) are in the middle zone, and the small arteries and arterioles that are normally below the limit of resolution are in the outer zone.  The visible small and midsized arteries (midzone) have sharp, clearly definable margins. As noted, this is because of the sharp border between water density and air density structures. In the standard, standing frontal (PA) chest film, the arteries in the lower zone are larger than those in the upper zone, at an equal distance from the hila. This is because of the effect of gravity on the normal, low-pressure lung circulation. That is, gravity leads to slightly greater intravascular volume at the lung bases than in the upper zones.
  • 31. This effect of gravity on the distribution of normal intravascular lung volume is reflected in a normal perfusion lung scan. Because the radionuclide is generally administered with the patient supine, there is a greater concentration posteriorly than anteriorly, as confirmed in the count rates. If the patient is sitting or standing when the radionuclide is injected, the count rate is greater at the lung base than at the apices.
  • 32. Evaluating the Chest Radiograph in Heart Disease  There is no single best way to read a chest film. A systematic approach to the evaluation of a chest radiograph is imperative to distinguish normal from abnormal and to define the underlying pathology and pathophysiology.  The first step is to define which type of film is being evaluated—PA and lateral, PA alone, or AP view (either portable or one obtained in the AP view because the patient is unable to stand).  The next step is to determine whether prior films are available for comparison. Many abnormalities are put into appropriate perspective by determining whether they are new. Common examples are a prominent aortic arch, visible major fissure related to prior inflammatory process, or widened superior mediastinum related to aortic ectasia , substernal thyroid, or enlarged azygous vein .
  • 33. Any system should incorporate a routine that includes a deliberate attempt to look at areas that are easily ignored. These include the thoracic spine, neck (for masses and tracheal position), costophrenic angles, lung apices, retrocardiac space, and retrosternal space. Looking at these areas enables definition of mediastinal position and cardiac and aortic situs and the presence of pleural effusions, scarring, or diaphragmatic elevation.  It is logical to evaluate the lung fields next. This should involve a careful search for infiltrates or masses, even when the primary concern is cardiovascular abnormalities. The logic is that many people with coronary artery disease have a history of tobacco abuse and are thus at increased risk for lung malignancies.  Cardiovascular disease states cause various and complex changes in the appearance of the chest radiograph. The overall size of the cardiac silhouette, its position, and the location of the ascending and descending aorta must be specifically evaluated.
  • 34. Cervical rib on the right side
  • 35. Dextrocardia and a right descending aorta are rare, particularly in adults, but are easy to check for and are important to recognize because of their association with congenital cardiac and abdominal situs abnormalities. It is also important to look at the site and position of the stomach. This information can be used to differentiate between a high diaphragm and a pleural effusion .  Cardiomegaly, accurately judged by the heart diameter exceeding half the diameter of the thorax on a PA film, is a common but nonspecific finding.It is probably most often seen as a result of ischemic cardiomyopathy following one or more myocardial infarctions.
  • 36. CARDIOMEGALY IN X-RAY CHEST(PA VIEW)  Trans cardiac diameter is measured as follows-  Mark a mid-vertical line along the spinous process.  Draw a horizontal line from the vertical line to the maximum convexity in the right cardiac border.  Draw another horizontal line from the vertical line to the maximum convexity in the left cardiac border  Line A+B=Transcardiac diameter Transthoracic diameter at the level of inner border of ninth rib.
  • 37. Cardiothoracic ratio=TCD/TTD  Normally cardiothoracic ratio is 33%- 50%(0.33-0.50).  Any increase in transcardiac diameter more then 2 cm,is significant if earlier X-rays are available for comparison.  In old age and emphysema, transcardiac diameter of 15 cm or more is taken as cardiomegaly irrespective of CT ratio.
  • 38. Assessment of pulmonary vasculature
  • 39. Evaluation of the pulmonary vascular pattern is difficult and imprecise but very important. As noted, the pattern varies with the patient's position (erect versus supine) and is altered substantially by underlying pulmonary disease. It is best to define pulmonary vascularity by looking at the middle zone of the lungs (i.e., the third of the lungs between the hilar region and peripheral region laterally) and comparing a region in the upper portion of the lungs with a region in the lower portion, at equal distances from the hilum.  Vessels should be larger in the lower lung but sharply marginated in the upper and lower zones. In normal individuals, the vessels taper and bifurcate and are difficult to define in the outer third of the lung. They normally become too small to be seen near the pleura  Two distinct patterns of abnormality are recognizable. When pulmonary arterial flow is increased, as in patients with a high-output state (e.g., pregnancy, severe anemia as in sickle cell disease, hyperthyroidism) or left-to-right shunt, the pulmonary vessels are seen more prominently than usual in the periphery of the lung.
  • 40. They are uniformly enlarged and can be traced almost to the pleura, but their margins remain clear. In contrast, in patients with elevated pulmonary venous pressure, the vessel borders become hazy, the lower zone vessels constrict and the upper zone vessels enlarge, and vessels become visible farther toward the pleura, in the outer third of the lungs
  • 41. Larry Elliots grading of Pulmonary Venous Hypertension
  • 42. Grade-1 pulmonary venous hypertension- The upper lobe veins becomes more prominent than the lower lobe veins- cephalisation
  • 43. Grade-2 pulmonary venous hypertension-  Kerleys lines are due to interlobular septal thickening due to lymphatic and venous drainage.  Kerleys A lines-Horizontal linear shadows towards the hilum.  Kerleys B lines-Horizontal and linear shadows towards the costophrenic angle.  Kerleys C lines-Crisscross between A and B.
  • 44. Chest X-ray PA view of 40 year old male with grade-II pulmonary venous hypertension- Top panel shows typical features of pulmonary venous hypertension with Kerley's lines and interstitial oedema. Bottom panel shows X- rays of the same patient 4 hours after treatment with diuretics.
  • 45. Grade –III pulmonary venous hypertension Alveolar edema, manifesting as bilateral diffuse patchy cotton wool opacities in the lung parenchyma.
  • 46. Grade IV pulmonary venous hypertension -results in bilateral miliary mottling -hemosiderosis -calcification -irreversible
  • 48. Right Atrium  Right atrial enlargement is essentially never isolated except in the presence of congenital tricuspid atresia or Ebstein anomaly. Both are rarely encountered, even in the pediatric age group.  The right atrium may dilate in the presence of pulmonary hypertension or tricuspid regurgitation, but right ventricular dilation usually predominates and prevents definition of the atrium.  The right atrial contour blends with that of the SVC, right main pulmonary artery, and right ventricle.
  • 49. Radiological features S/O Right atrial enlargement in PA view  Right cardiac border becomes more convex and elongated. It forms more then 50% of right cardiac border.  Distance from mid-vertical line to the maximum convexity in the right border is more then 5cm in adults and more then 4cm in children which results in cardiomegaly.  Right atrial border extends beyond three intercostal spaces.  Dilation of superior vena cava.
  • 50. Right atrial enlargement in LAO view  Normally in LAO view, upper half of anterior cardiac border is formed by right atrium and lower half by right ventricle.  When right atrium enlarges the upper anterior cardiac border becomes squared giving a box like appearance.  LAO is the best view to visualise right atrial enlargement.
  • 51.
  • 52. Right atrial enlargement in a patient with rheumatic mitral stenosis. There is left atrial enlargement and mitralisation too, of heart.
  • 53. Right Ventricle  The classic signs of right ventricular enlargement are a boot-shaped heart and filling in of the retrosternal air space.The former is caused by transverse displacement of the apex of the right ventricle as it dilates. In adults, it is rare for the right ventricle to dilate without left ventricular dilation, so this boot shape is not often obvious. It is most commonly seen as an isolated finding in congenital heart disease, typically in tetralogy of Fallot. As the right ventricle dilates, it expands superiorly as well as laterally and posteriorly, explaining the well-marginated increase in density in the retrosternal airspace.  The classic teaching is that in a lateral chest radiograph in normal patients, the soft tissue density is confined to less than one third of the distance from the suprasternal notch to the tip of the xephoid. If the soft tissue fills in by more than one third, in the absence of other explanations, it is a reliable indication of right ventricular enlargement.
  • 54. Right ventricular enlargement PA view-Rounded and elevated apex from the left dome of the diaphragm Right lateral view- Obliteration of retrosternal space
  • 55. Chest radiographs of a 59-year-old woman with a history of rheumatic heart disease and mitral stenosis. a, PA view demonstrates enlarged cardiac silhouette, with suggestion of a double density seen through the heart (left atrial enlargement), prominent convexity of the left atrial appendage (small arrow), and slightly elevated cardiac apex (large arrow), suggestive of right ventricular (rather than left ventricular) enlargement. there is significant elevation of the pulmonary venous pressures. B, The lateral view confirms marked right ventricular (arrow) and left atrial (small arrows) enlargement. note filling in of the retrosternal airspace. la = left atrium; lv = left ventricle.
  • 56. Left Atrium  Several classic signs define left atrial enlargement-  The first is dilation of the left atrial appendage, seen as a focal convexity where there is normally a concavity between the left main pulmonary artery and left border of the left ventricle on the frontal view .  Second, because of its location, as the left atrium enlarges, it elevates the left main stem bronchus. In so doing, it widens the angle of the carina,normal being 45-75 degrees.  Third, with marked left atrial enlargement, a double density can be seen on the frontal view because the left atrium projects laterally toward the right and posteriorly, and the discrete outline of the blood-filled left atrium is surrounded by air-filled lung .  Finally, on the lateral film, left atrial enlargement appears as a focal, posteriorly directed bulge .
  • 57.
  • 58. Chest X-ray PA view of two patients with varying degree of left atrial enlargement in rheumatic mitral stenosis
  • 59. Left Ventricle  Left ventricular enlargement is characterized by a prominent, downwardly directed contour of the apex, as distinguished from the transverse displacement seen with right ventricular enlargement.  On the PA film, the overall cardiac contour is also usually enlarged, although this is a nonspecific finding.  It may also be seen inferiorly, pushing the gastric bubble . Such left ventricular enlargement is an illustration of findings that lie outside the usual confines of the chest and another example of the value of looking at the entire chest radiograph. Focal left ventricular enlargement in adults is most commonly seen in the presence of aortic insufficiency (with aortic root dilation; or mitral regurgitation (with left atrial dilation.  In contrast, because aortic stenosis is characterized by left ventricular hypertrophy rather than dilation, the left ventricle is dilated on the chest film only when aortic stenosis is accompanied by left ventricular failure.
  • 60.
  • 61. Chest radiographs of a 63-year-old man with chronic aortic regurgitation. A, PA view shows downward displacement of the apex (arrow), suggestive of left ventricular enlargement. There is prominence and enlargement of the ascending aorta, creating a convex right border of the mediastinum. B, Lateral view shows prominent left ventricular enlargement (arrowheads). The aortic root is markedly enlarged in the retrosternal airspace but is separate from the sternum (in contrast to findings in right ventricular enlargement).
  • 63. Pulmonary Arteries  The main pulmonary artery can appear abnormal in many clinical settings. In the presence of pulmonic stenosis, the main pulmonary artery and left pulmonary artery dilate . This dilation is thought to be caused by the jet effect on the vessel wall of the blood flow through the stenotic valve, coupled with the anatomy. That is, the main pulmonary artery continues straight into the left main pulmonary artery but the right comes off at a fairly sharp angle and is not generally affected by the jet from the stenotic valve. This enlargement can be seen with a prominent left hilum on the frontal view and a prominent pulmonary outflow tract on the lateral view.  It is important to remember that the pulmonic valve lies more superiorly in the outflow tract and more anteriorly than the aortic valve .
  • 64. Chest radiographs of a 56-year-old asymptomatic woman with incidentally discovered pulmonic stenosis. A, PA view shows marked enlargement of the main pulmonary trunk extending into the left main pulmonary artery (arrow). B, Lateral view confirms prominence of the pulmonary outflow tract and main and left pulmonary arteries (arrows).
  • 65. Aorta  The most commonly seen abnormality of the aorta is dilation, and the way the aorta dilates is a function of the underlying pathology . It is often possible to define the pathology by a combination of the pattern of dilation and associated cardiac abnormalities.  On the frontal chest radiograph, aortic dilation appears as a prominence to the right of the middle mediastinum . There is also a prominence in the anterior mediastinum on the lateral view, behind and superior to the pulmonary outflow tract.  Dilation of the aortic root is seen in the presence of aortic valve disease (both stenosis and regurgitation) but more frequently has other causes, such as long-term, poorly controlled systemic hypertension or generalized atherosclerosis with ectasia.
  • 66. Chest radiographs of a 65-year-old woman with severe aortic stenosis. A, Frontal view shows a prominent aortic root, to the right of the midline (arrowheads). Note absence of cardiomegaly and presence of normal pulmonary vascular pattern. B, Lateral view demonstrates calcification of the aortic valve leaflets (arrows), suggestive of a bicuspid valve. There is a prominent, mildly dilated aortic root (arrowheads).
  • 67. Pleura and Pericardium  The pleura and pericardium also require systematic evaluation. The pericardium is rarely distinctly definable on plain films of the chest.There are two situations, however, in which it can be seen; in the presence of a large pericardial effusion, the visceral and parietal pericardium separate. Because there is a fat pad associated with each, it is sometimes possible to make out two parallel lucent lines (i.e., fat) on the lateral film, usually in the area of the cardiac apex, with density (fluid) between them. CMRI, echocardiography, and CT, however, are all far more reliable for defining a pericardial effusion  Nonetheless, if the cardiac silhouette is enlarged on the chest radiograph, it is important to look for specific explanations. Although cardiac dilation and valvular disease are more common causes, the presence of an unsuspected effusion is worth considering. Typically, the cardiac silhouette has a water bottle shape in the presence of a pericardial effusion, but this shape is not in itself diagnostic.
  • 68. Pericardial effusion  Cardiomegaly  Cardio phrenic angles become more and more acute.  Narrow vascular pedicle  Marked change in cardiac silhouette in decubitus position is very diagnostic.
  • 69. Pleural and pericardial calcification  Pleural and pericardial calcification can occur, but are often not obvious . Pericardial calcification is associated with a history of pericarditis. Although there are multiple causes, tuberculosis and various viruses are the most common. Such calcification is usually thin and linear and follows the contour of the pericardium. Because the calcification is thin, it is often seen only on one view.  Myocardial calcification secondary to a large myocardial infarction with transmural necrosis is rare but can generally be distinguished from pericardial calcification. It tends to appear thicker, more focal, and less consistent with the outer contour of the heart.  Pleural calcification is easily distinguishable from pericardial calcification and is essentially pathognomonic for asbestos exposure. It is associated with a high risk of malignant mesothelioma but is not diagnostic of this type of tumor.
  • 70. Chest radiographs of a 45-year-old man with calcific pericarditis. A, PA view is essentially normal. B, Lateral view demonstrates thin, irregular calcification of pericardium around the left ventricular contour.
  • 71. Chest radiograph showing marked pericardial calcification in a patient with constrictive pericarditis.
  • 72. Cardiac valves calcification Calcified cardiac valves Chest PA view Aortic valve will be at the level of T6-T7 overlying the midline area. Mitral valve will be at T8 level away from the midline in the paravertebral region. Lateral view Aortic calcification is above an imaginary line from left bronchus to RV apex and mitral calcification is below the line.
  • 74. Rheumatic valvular heart diseases  Rheumatic Mitral Stenosis  X-ray chest PA view  The typical mitralisation.  Less prominent aortic knuckle.  Obliteration of pulmonary bay due to prominent main and left pulmonary arteries.  Prominent left atrial appendage.  Straightening of convex contour of left ventricular border due to hypoplasia and hypovolumia.
  • 75. Top panel shows mitralisation. Bottom panel shows gross enlargement of main pulmonary artery, left atria and left atrial appendage dilation and right ventricular enlargement.
  • 77. Mitral regurgitation  Left atrial enlargement  Left ventricular enlargement  Right atrial enlargement
  • 78. MS+MR
  • 82. Congenital heart diseases-Acyanotic  Without a shunt  Pulmonary valvular stenosis  The radiological features are-  Pulmonary oligaemia  Post-stenotic dilatation of main pulmonary artery  Right ventricular enlargement  Right atrial enlargrment
  • 84. Primary pulmonary hypertension  X-ray chest PA view  Moderate to marked enlargement of main pulmonary artery and its proximal branches.  Peripheral pulmonary arteries are diminished and pruned resulting in clear peripheral lung fields.  Absence of pulmonary venous hypertension.  Small and inconspicuous ascending aorta  Right ventricular and right atrial enlargement  Absent left atrial enlargement
  • 86. Congenital heart diseases-Acyanotic  With a shunt  Shunt at atrial level  Shunt at ventricular level  Shunt at aorto pulmonary level  Pulmonary plethora is common in all left to right shunts.
  • 87. Atrial septal defect  Ostium secundum ASD  Enlargement of RV,RA and LA.  Left ventricle is hypovolaemic and hypoplastic.  Right pulmonary artery is more prominent than left pulmonary artery giving the radiological sign of jug-handle appearance.  Ostium primum ASD Left ventricular enlargement in addition to the radiological features of OS –ASD.
  • 90. VSD  All four chambers are involved.  The ascending aorta is inconspicuous.  Both pulmonary arteries are equally prominent.
  • 91. Patent Ductus Arteriosus  All the four chambers are involved.  Prominent ascending aorta.  There may be speck of calcium when PDA is calcified.It is comma shaped between aortic knuckle and main pulmonary artery and is known as Cap of Zin.  Both pulmonary arteries are equally dilated.
  • 92. Congenital cyanotic heart diseases  Increased pulmonary arterial blood flow  Complete transposition of great arteries(d-TGA)  Absent thymic shadow  Narrow vascular pedicle  Increased CT ratio with egg lying on its side appearance  Pulmonary plethora
  • 93. Truncus Arteriosus  All four chambers are dilated with pulmonary plethora.  In one – third of cases right aortic arch is present.
  • 94. TAPVC  Supracardiac type is the commonest and will have a distinctive figure of 8 or snowman silhouette or cottage loaf.The upper portion of figure of 8 is formed by the dilated left vertical vein and right superior vena cava.The lower portion consists of dilated right atrium and right ventricle.
  • 95. Decreased pulmonary arterial blood flow  Tetralogy of Fallot  No cardiomegaly  Uplifted apex-boot shaped or coeur en sabot appearance  Pulmonary oligaemia  Dilated ascending aorta with right aortic arch in 25% of cases  Bilateral reticular formation due to bronchopulmonary collaterals  Unilateral rib notching after BT shunt
  • 96. Ebstein anomaly of the tricuspid valve  Cardiomegaly with dilated right atrium and right ventricular infundibulum accounts for the box like silhouette with normal or decreased pulmonary blood flow,resembling pericardial effusion.
  • 97. Coarction of aorta  Three sign on chest X-ray  E sign or reverse 3 sign in barium swallow  Rib notching of 3rd to 8th posterior ribs along its lower border usually after the age of 9 years
  • 98. Cardiac malposition Situs solitus Situs inversus totalis
  • 99. Implantable Devices and Other Postsurgical Findings  A final important and broad area concerns the chest radiograph following surgery or other procedures. In these situations, it is crucial to recognize devices that have been implanted and changes that may occur. Among the most common are various valve prostheses, pacemakers and ICDs, intra- aortic counterpulsation balloons , and ventricular assist devices . There are also clear changes that occur after surgery, such as the presence of clips on the side branches of saphenous veins used for coronary artery bypass grafting and retrosternal blurring and effusions  Some of these findings may be temporary, such as lines and tubes associated with surgery and effusions. Pacemakers and ICDs present specific questions . The first is whether the leads are intact and the second is the position of the tips. Although course and tip position are generally confirmed fluoroscopically at the time of placement, malposition can occur. If there are two leads, the tips should generally be in the anterolateral wall of the right atrium and apex of the right ventricle.
  • 100. If the leads are not positioned in this way, the reasons should be carefully determined. That is, are they positioned because of error or anatomic variants (e.g., a persistent left SVC that empties into the coronary sinus and then the right atrium or because the lead belongs in the coronary sinus. Additionally, the position of the wires and of valve prostheses can help in the definition of specific chamber enlargement
  • 101. AV sequential pacemaker in right infra clavicular subcutaneous pocket. J shaped atrial lead is seen in right atrial appendage.Tip of ventricular lead is in right ventricular apex.
  • 102. Biventricular pacing. Atrial lead is in right atrium; right ventricular lead is in RV apex, left ventricular lead is introduced through coronary sinus to pace left ventricular epicardium.
  • 103. Conclusion  Chest radiographs provide a wealth of physiologic and anatomic information. As such, they play a central role in the evaluation and management of patients with a wide variety of cardiovascular and other disorders.  The radiation dose inherent in obtaining x-rays should always be considered.  Portable chest films should be used as infrequently as possible because the information they provide is limited and may even be misleading (e.g., in defining cardiomegaly or in ruling out a pneumothorax or effusion).  Standard 6-foot frontal and lateral chest x-rays, on the other hand, are almost always of value. Whether recorded conventionally or digitally, if they are evaluated carefully using a systematic approach and, whenever possible, compared with prior chest radiographs, it is hard to overstate their importance.