ReaMetrix Overview

ReaMetrix at a glance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SAN CARLOS (HEAD OFFICE) BANGALORE (MANUFACTURING & R&D FACILITY) SINGAPORE (REPRESENTATIVE OFFICE)

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Assay Development Stable Cell Lines Custom Conjugations Instrumentation ReaMetrix Competencies Core competencies drive Diagnostics & Research businesses

State of the art Indian Facility

Driving Value Through Innovation The ReaMetrix Experience PE TR Cy5 Cy5.5 Cy7

Immunofluorescent Conjugates ,[object Object],[object Object],Innovation in design and process

Identifying Alternate Dyes – Developing a Palette ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],PE TR Cy5 Cy5.5 Cy7 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],APC Cy5.5 A700 Cy7 Licor800 High Quality Fluorescent Dyes at Affordable Cost

Developing Immunofluorescent Conjugates ,[object Object],Incoming Quality Control Acquire unlabeled antibodies & other reagents from third parties Component purification Functional validation Unitizing and packaging Deliver finished product to customer Specification/ Quality Assurance Purification Process quality control testing Conjugation Process is our Product

Key features of ReaMetrix conjugates ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Development conjugates for Leukemia-Lymphoma ,[object Object],[object Object],[object Object],[object Object]

Products Developed at ReaMetrix ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Value addition through Innovation

Typical Characteristics of ReaMetrix Products ,[object Object],[object Object],[object Object],[object Object],[object Object]

Reagent for monitoring HIV progression through the Enumeration of CD3+CD4+ Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],CD4 0 300 600 900 1200 1500 0 300 600 900 1200 1500 Rmx Dry T-STAT Coulter TetraChrome r = 0.994

ReaTcount – Affordable Alternative to FACScount ™ ,[object Object],[object Object],[object Object],[object Object],Excellent Correlation

ReaPan B27 – For typing HLA B27 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ReaPan S34 – For Enumerating CD34 cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

New Product Ideas Under development in our labs

ReaPanMicro – Presence/Absence Test for Bacteria in Urine ,[object Object],[object Object],[object Object],[object Object],[object Object],Culture Negative Culture Positive 146 Samples By Culture 67 22 TN 100.0% NPV 72.2% PPV 0 Negative by Flow 57 Positive by Flow TP Overall

Bacteria Speciation Using Fluorescent Tags ,[object Object],[object Object],[object Object],[object Object],[object Object],A B C D

Products under development - Controls ,[object Object],[object Object],[object Object],[object Object],[object Object],http://www.finddiagnostics.org/news/newsletters/issue_10-jun_08/page03.shtml Dot plots of 20 day stabilized blood samples

Products under development ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Leukocytes Beads

Products under development ,[object Object],[object Object],[object Object]

ReaDev Extending Innovations to Partners

Stable Cell Line Development ,[object Object],Stable CHOKI cells expressing IL8RB stained with fluorescently labeled chemokine IL8

Bead Based Assay Development for US biotechnology Company ,[object Object],[object Object],[object Object],[object Object],Antibody Screening ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Bead Based Assay Format Antibody Pair Selection Assay Development R E A M E T R I X P R O C E S S Project Deliverables

Expression of cardiovascular protein for MAb development for US Healthcare Company ,[object Object],[object Object],[object Object],[object Object],Expression ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Transfection Protein Purification & Characterization R E A M E T R I X P R O C E S S Project Deliverables ,[object Object],[object Object],[object Object],[object Object],[object Object],Lipids DNA Lipid complex Cloned DNA Secreted Protein

Towards Affordable Diagnostics ReaMetrix Approach

Clinical Information Generation – Current Scenario Sample journey and cost accumulation Acquire Process Run Provide Results Transport Collection centre Path Lab Doctor Hospital Centralized Path Lab Syringe/Vacutainer/Overheads Cold chain/Courier Tech Labor + Reagent Capital Equipment Amortization Lab Infrastructure Overheads ,[object Object],[object Object],[object Object],Layers of margin at every step

Issues with the current scenario ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Local economic activity needs to be promoted for enhanced reach of diagnostics

What is the ReaMetrix Solution? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],The ReaScan System – A Total Systems Offering

Summary ,[object Object],[object Object]

Manufactured by ReaMetrix India Pvt. Ltd. 50-B, II Phase, Peenya Industrial Area Peenya, Bangalore 560058, India Ph: +91-80-28378693/5, Fax: +91-80-41172451 E-mail: info@reametrix.com www.reametrix.com Further details:

ReaMetrix Overview

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ReaMetrix Overview