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BREAST RECONSTRUCTION WITH DIEP
  FLAP-SPECIAL CONSIDERATIONS

  Stamatis Sapountzis M.D

  Division of Plastic Surgery
  China Medical University Hospital
Goals of Breast Reconstruction
 Provide permanent breast contour


 Make the breasts look balanced


 Avoid the need for external prosthesis


 Re-establish normalcy and confidence
Breast Reconstruction

 Implant Based
 Autologous Tissue
 Implant + Autologous Tissue
Breast Reconstruction

 Implant Based
 Autologous Tissue
 Implant + Autologous Tissue
History
   Vincenz Czerny
Oncology, gynecology

                       In 1895 he published the first account of a
                       breast implant which he had carried out, by
                       transferring a benign lipoma to "avoid
                       asymmetry" after removing a tumor in a
                       patient's breast.
                       1879 performed the first total hysterectomy
                       via the vagina
Why Breast Reconstruction
with abdominal tissue became
          popular?
June 2010




87 tissue expander/implant

116 latissimus Dorsi

119 pedicle TRAM

117 DIEP flap
Free DIEP > Free TRAM



                           (Plast. Reconstr. Surg. 124: 752, 2009


  Donor Site Morbidity

              DIEP patients has one-half the risk
                of abdominal bulge or hernia
Plast. Reconstr. Surg. 125: 772, 2010.)



                                          Each perforators was
                                          injected with contrast and
                                          the flaps were subjected to
                                          dynamic computed
                                          tomography scanning.




Three-dimensional and four-dimensional computed tomographic
angiography was utilized to reappraise the zones of vascularity.
Hartrampf   Holm
Three-dimensional computed tomography
                      angiogram




Perfusion tends to stay in one hemi-   The injected medial perforator was connected
abdomen.                               to the contralateral medial row perforator
                                       through indirect linking vessels via the
                                       subdermal plexus.
(Above) Lateral row perforator is injected. At least two sets of linking vessels need
to be crossed to reach the midline

(Below) Medial row perforator is injected. Fewer linking vessels are required to cross
the midline,thus contrast flows into zone II more easily, hence a more centralized
perfusion..
Illustration of a medial perforator DIEP
flap, in which perfusion is more
centralized and has a bigger vascular
territory.
These are useful for large breast
reconstructions.




Medial perforator DIEP flaps follow
Hartrampf zones of perfusion. Zone II is
on the contralateral hemi-abdomen.
Illustration of a lateral perforator DIEP
flap, in which perfusion is more
lateralized. These are useful for small to
moderate sized and bilateral breast
reconstructions.




 Lateral perforator DIEP flaps follow Holm’s
 zones of perfusion.
 Zone II is on the ipsilateral hemi-abdomen.
Intraoperatively angiography following administration of 5 mg of
    indocyanine green in aperipheral intravenous catheter
Results
Comparison of perfusion: DIEP – MS TRAM –Pedicle TRAM




                       not a significant difference between
                                   zones 2 and 3
(Plast. Reconstr. Surg. 128: 581e, 2011




 There were 228 patients, with 120 medial (52.6
percent) and 108 lateral (47.4 percent) branch flaps
Regardless of whether the dominant perforator is laterally
   or medially located, as long as it is included, a safe flap can be
harvested and the perfusion related complications can be reduced to
                      an absolute minimum.
3 Key Points

1. Vessel diameter is important and
   Poiseuille’s law is determining.

   The flow through a tube is related to the
   fourth power of the radius of a vessel


   The flow in a vessel with a 2-mm
   diameter is approximately 16 times
   higher than in a vessel with a diameter of
   1 mm
3 Key Points

1. Vessel diameter is important and Poiseuille’s law is determining




2. The central positioning of the perforator in the flap is essential



3. The number and three-dimensional structure of the branches of the
   perforator, once it has pierced the deep fascia, will determine which
   areas of the flap will be vascularized
Computed tomographic scan of a perforator originating from the lateral
branch of the right deep inferior epigastric artery with a perforator that
bends off laterally and vascularizes only the most lateral and ipsilateral
part of the flap.



 The Perfusion of the conventionally designed flap will be extremely poor
Multi-detector CT angiography scan

 Info on perforator location, diameter (>0.3mm, >1mm
   included), intramuscular course, high spatial resolution
   allows multi-planar evaluation (3D view), less habitus
   dependent, predictive value on outcome (DIEP Vs MS
   free TRAM), can evaluate SIEA system

 Reduced operative time. Sensitivity 99.6% (Rozen et al.)
 Op time reduction average 100min (Casey et al, Smit et al, Masia et al)

 Expensive
 Radiation dose
 Contrast
(Plast. Reconstr. Surg. 119: 18, 2007
Subfascial DIEP Flap
Dissection of the lower abdomen skin       Longitudinal incision to the anterior rectus
and fat flap from the underlying           sheath approximately 0.5 cm medial to the
aponeurosis terminates when the            lateral border
lateral border of anterior rectus sheath
is reached
The semilunar incision line (dotted line) through the
anterior rectus sheath that is lateral to the lateral row
of perforators
Identification of the lateral row of   Transverse incision of the aponeurosis
perforators of the deep inferior       toward the perforator
epigastric artery (DIEA) in the
subaponeurotic layer.
Subaponeurotic blunt dissection of the        The anterior rectus sheath has been
deep inferior epigastric artery perforators   incised and raised exposing the
is performed                                  perforators piercing the posterior surface
                                              of the fascia
Advantages
 Save time: easy plane between fascia and
  muscle

 Safe dissection: blunt dissection


 Easy to define the largest perforator
Raising a flap with a skin paddle with less vertical height reduces the donor
site morbidity, especially in terms of reducing the risk of wound dehiscence,
as tight abdominal closure is avoided (e.g in thin patients)


The technique we describe offers the patient a naturally shaped breast that
can be achieved without the need to raise a very large abdominal flap
Projection the mastectomy scar onto the contralateral breast and measurement of
the dimensions of skin in the area of the breast inferior to this imaginary scar line
An inverted V-shaped flap is designed on the inferior mastectomy skin flap and a
template of this also made

This triangular template is then superimposed on the inferior aspect of the template
and excised because this part of the skin in the new breast will be created by the
mastectomy skin flap
When the breast template is opened and flattened the shape of the required
flap is almost rectangular.

The V shaped scar is on the underside of the breast occupying a natural
aesthetic subunit of the breast, thus making it inconspicuous.

A fatty layer is also included from the upper abdominoplasty flap to
partially fill the upper poles of the new breast.
What is the best way to
    inset the flap?
Two-esthetic unit breast reconstruction. (A)         Single-esthetic unit breast reconstruction.
The mastectomy scar is excised. (B) The DIEAP        (A) The skin in between the mastectomy scar
flap is inset in the center of the breast mound      and the new inframammary fold is de-
creating a breast consisting of two-esthetic         epithelialized. (B) The DIEAP flap extends to
units: the native skin and the flap’s skin paddle.   the inframammary fold, reconstructing the
                                                     entire breast
A skin envelope is created with tissue expander and then the expander is
replaced with a de-epithelialised flap, leaves a breast with the original
mastectomy scar and no skin island
Can we perform abdominal
flaps after liposuction or
  with the existence of
vertical laparotomy scars?
8 cases (7 autologous breast reconstruction, 1
thigh reconstruction.
All patients had a vertical abdominal midline
scar as a result of a previous surgical
intervention.
•In the past was contraindication

•Preoperative colour duplex or CT angiography is mandatory

•The dissection of the perforator flaps was sometimes more
difficult due to increased fibrosis and scar formation of the
subcutaneous tissue.
(Ann Plast Surg 2011;67: 251–254)

11 DIEPS contained a midline scar




           In flaps with a midline scar approximately 70%
           of the entire flap volume appeared to be well
           vascularized (pink area) after harvest
Plastic and Reconstructive Surgery • May 2012
Thank you

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DIEP Flap - For Breast Reconstruction

  • 1. BREAST RECONSTRUCTION WITH DIEP FLAP-SPECIAL CONSIDERATIONS Stamatis Sapountzis M.D Division of Plastic Surgery China Medical University Hospital
  • 2. Goals of Breast Reconstruction  Provide permanent breast contour  Make the breasts look balanced  Avoid the need for external prosthesis  Re-establish normalcy and confidence
  • 3. Breast Reconstruction  Implant Based  Autologous Tissue  Implant + Autologous Tissue
  • 4. Breast Reconstruction  Implant Based  Autologous Tissue  Implant + Autologous Tissue
  • 5. History Vincenz Czerny Oncology, gynecology In 1895 he published the first account of a breast implant which he had carried out, by transferring a benign lipoma to "avoid asymmetry" after removing a tumor in a patient's breast. 1879 performed the first total hysterectomy via the vagina
  • 6. Why Breast Reconstruction with abdominal tissue became popular?
  • 7. June 2010 87 tissue expander/implant 116 latissimus Dorsi 119 pedicle TRAM 117 DIEP flap
  • 8. Free DIEP > Free TRAM (Plast. Reconstr. Surg. 124: 752, 2009 Donor Site Morbidity DIEP patients has one-half the risk of abdominal bulge or hernia
  • 9.
  • 10.
  • 11. Plast. Reconstr. Surg. 125: 772, 2010.) Each perforators was injected with contrast and the flaps were subjected to dynamic computed tomography scanning. Three-dimensional and four-dimensional computed tomographic angiography was utilized to reappraise the zones of vascularity.
  • 12. Hartrampf Holm
  • 13. Three-dimensional computed tomography angiogram Perfusion tends to stay in one hemi- The injected medial perforator was connected abdomen. to the contralateral medial row perforator through indirect linking vessels via the subdermal plexus.
  • 14. (Above) Lateral row perforator is injected. At least two sets of linking vessels need to be crossed to reach the midline (Below) Medial row perforator is injected. Fewer linking vessels are required to cross the midline,thus contrast flows into zone II more easily, hence a more centralized perfusion..
  • 15.
  • 16. Illustration of a medial perforator DIEP flap, in which perfusion is more centralized and has a bigger vascular territory. These are useful for large breast reconstructions. Medial perforator DIEP flaps follow Hartrampf zones of perfusion. Zone II is on the contralateral hemi-abdomen.
  • 17. Illustration of a lateral perforator DIEP flap, in which perfusion is more lateralized. These are useful for small to moderate sized and bilateral breast reconstructions. Lateral perforator DIEP flaps follow Holm’s zones of perfusion. Zone II is on the ipsilateral hemi-abdomen.
  • 18. Intraoperatively angiography following administration of 5 mg of indocyanine green in aperipheral intravenous catheter
  • 19. Results Comparison of perfusion: DIEP – MS TRAM –Pedicle TRAM not a significant difference between zones 2 and 3
  • 20. (Plast. Reconstr. Surg. 128: 581e, 2011 There were 228 patients, with 120 medial (52.6 percent) and 108 lateral (47.4 percent) branch flaps
  • 21.
  • 22. Regardless of whether the dominant perforator is laterally or medially located, as long as it is included, a safe flap can be harvested and the perfusion related complications can be reduced to an absolute minimum.
  • 23. 3 Key Points 1. Vessel diameter is important and Poiseuille’s law is determining. The flow through a tube is related to the fourth power of the radius of a vessel The flow in a vessel with a 2-mm diameter is approximately 16 times higher than in a vessel with a diameter of 1 mm
  • 24. 3 Key Points 1. Vessel diameter is important and Poiseuille’s law is determining 2. The central positioning of the perforator in the flap is essential 3. The number and three-dimensional structure of the branches of the perforator, once it has pierced the deep fascia, will determine which areas of the flap will be vascularized
  • 25. Computed tomographic scan of a perforator originating from the lateral branch of the right deep inferior epigastric artery with a perforator that bends off laterally and vascularizes only the most lateral and ipsilateral part of the flap. The Perfusion of the conventionally designed flap will be extremely poor
  • 26. Multi-detector CT angiography scan  Info on perforator location, diameter (>0.3mm, >1mm included), intramuscular course, high spatial resolution allows multi-planar evaluation (3D view), less habitus dependent, predictive value on outcome (DIEP Vs MS free TRAM), can evaluate SIEA system  Reduced operative time. Sensitivity 99.6% (Rozen et al.)  Op time reduction average 100min (Casey et al, Smit et al, Masia et al)  Expensive  Radiation dose  Contrast
  • 27. (Plast. Reconstr. Surg. 119: 18, 2007
  • 28.
  • 30. Dissection of the lower abdomen skin Longitudinal incision to the anterior rectus and fat flap from the underlying sheath approximately 0.5 cm medial to the aponeurosis terminates when the lateral border lateral border of anterior rectus sheath is reached
  • 31. The semilunar incision line (dotted line) through the anterior rectus sheath that is lateral to the lateral row of perforators
  • 32. Identification of the lateral row of Transverse incision of the aponeurosis perforators of the deep inferior toward the perforator epigastric artery (DIEA) in the subaponeurotic layer.
  • 33. Subaponeurotic blunt dissection of the The anterior rectus sheath has been deep inferior epigastric artery perforators incised and raised exposing the is performed perforators piercing the posterior surface of the fascia
  • 34.
  • 35. Advantages  Save time: easy plane between fascia and muscle  Safe dissection: blunt dissection  Easy to define the largest perforator
  • 36.
  • 37. Raising a flap with a skin paddle with less vertical height reduces the donor site morbidity, especially in terms of reducing the risk of wound dehiscence, as tight abdominal closure is avoided (e.g in thin patients) The technique we describe offers the patient a naturally shaped breast that can be achieved without the need to raise a very large abdominal flap
  • 38. Projection the mastectomy scar onto the contralateral breast and measurement of the dimensions of skin in the area of the breast inferior to this imaginary scar line
  • 39. An inverted V-shaped flap is designed on the inferior mastectomy skin flap and a template of this also made This triangular template is then superimposed on the inferior aspect of the template and excised because this part of the skin in the new breast will be created by the mastectomy skin flap
  • 40. When the breast template is opened and flattened the shape of the required flap is almost rectangular. The V shaped scar is on the underside of the breast occupying a natural aesthetic subunit of the breast, thus making it inconspicuous. A fatty layer is also included from the upper abdominoplasty flap to partially fill the upper poles of the new breast.
  • 41.
  • 42. What is the best way to inset the flap?
  • 43. Two-esthetic unit breast reconstruction. (A) Single-esthetic unit breast reconstruction. The mastectomy scar is excised. (B) The DIEAP (A) The skin in between the mastectomy scar flap is inset in the center of the breast mound and the new inframammary fold is de- creating a breast consisting of two-esthetic epithelialized. (B) The DIEAP flap extends to units: the native skin and the flap’s skin paddle. the inframammary fold, reconstructing the entire breast
  • 44.
  • 45. A skin envelope is created with tissue expander and then the expander is replaced with a de-epithelialised flap, leaves a breast with the original mastectomy scar and no skin island
  • 46.
  • 47. Can we perform abdominal flaps after liposuction or with the existence of vertical laparotomy scars?
  • 48. 8 cases (7 autologous breast reconstruction, 1 thigh reconstruction. All patients had a vertical abdominal midline scar as a result of a previous surgical intervention.
  • 49. •In the past was contraindication •Preoperative colour duplex or CT angiography is mandatory •The dissection of the perforator flaps was sometimes more difficult due to increased fibrosis and scar formation of the subcutaneous tissue.
  • 50. (Ann Plast Surg 2011;67: 251–254) 11 DIEPS contained a midline scar In flaps with a midline scar approximately 70% of the entire flap volume appeared to be well vascularized (pink area) after harvest
  • 51.
  • 52. Plastic and Reconstructive Surgery • May 2012

Notas do Editor

  1. Note the evident patchworkeffect of the flap 11 months postoperatively