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Denis Bernardi Bichuetti
Professor Adjunto, Disciplina de Neurologia
bichuetti@unifesp.br
PESQUISA CLÍNICA
CONFLITOS DE INTERESSE
• Suporte a atividades individuais ou serviços prestados a:
– Merck Serono
– TEVA Pharmaceuticals
– Biogen Idec
– Bayer Health Care Pharma
– Genzyme - Sanofi Aventis
– Novartis
– Roche
– Consultor e Blogueiro da AME
Esclerose	
Múltipla
Perda	de	força
Dificuldade	de	
se	locomover
Fadiga
Direitos	do	
paciente
Dor
Espasticidade
Dificuldades	
visuais
Alterações	
urinárias
Constipação
Remédios	/	
efeitos	
colaterais
Alteração	de	
sensibilidade
Alteração	na	
memória
Tremor	/	falta	
de	
coordenação
Paciente
Cônjuge
Amigos
Família
LazerTrabalho
Tratamento
Filhos
17 h30   denis bichuetti -fas 2016
INDIVIDUALIZAÇÃO
Clínica Genética
Terapia Imunologia
TMO
Estudos clínicos
Imunossupressão
Alemtuzumabe
Natalizumabe
Fingolimode
Fumarato
Fumarato, Fingolimode
Glatiramer / ßINF / Teriflunomida
ESCALONAMENTO TERAPÊUTICO 2016
Paciente
EDSS
T25FW
9 Hole Peg test
Teste de
Resistência
Ressonância
Neuropsicológic
o
SDMT
Acuidade visual
com contraste
OCT
Qualidade de
vida
Fadiga
Depressão
Outras
especialidades
Custo
Tempo de
consulta
Disponibilidade Viabilidade
OS 4 QUADRANTES
(I)
MÉDICO
Como pessoa
(II)
DOENTE
Como pessoa
(IV)
MEDICINA
Como ciência
(III)
SISTEMA
Como ambiente
Developing the Knowledge Base ofFamily Practtice
Stange KC, 2001
Denis Bernardi Bichuetti
Professor Adjunto, Disciplina de Neurologia
bichuetti@unifesp.br
PESQUISA CLÍNICA

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17 h30 denis bichuetti -fas 2016