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Also known as: Tricarboxylic acid cycle TCA cycle Kreb’s Cycle
 
 
The  Krebs Cycle  is the  Third Stage  of Aerobic Respiration
The  Krebs Cycle  is the  Third Stage  of Aerobic Respiration
The  Krebs Cycle  is the  Third Stage  of Aerobic Respiration Takes place in the  matrix  of the mitochondria.
The  Krebs Cycle  is the  Third Stage  of Aerobic Respiration Takes place in the  matrix  of the mitochondria. It happens once for every pyruvate molecule in glycolysis….
The  Krebs Cycle  is the  Third Stage  of Aerobic Respiration Takes place in the  matrix  of the mitochondria. It happens once for every pyruvate molecule in glycolysis…. ..and so it goes round twice for every glucose molecule that enters the respiration pathway.
Sir Hans Krebs – on his bike!
 
AcetylCoA  (2C) from the link reaction combines with  oxaloacetate (4C) to form citrate (6C).  CoA  is released back to the  link reaction  to be reused
The  6-carbon citrate  is  decarboxylated  – loses  CO 2  – to give a  5-carbon molecule
Both the citrate and the 5-carbon molecule formed from it are  dehydrogenated  (lose  hydrogen ) in the cycle to reduce the  coenzymes NAD  and  FAD
Overall, 3  reduced NAD +   and 1  reduced FAD  are produced. These coenzymes not carry the  hydrogen  to the  electron transport chain  (etc)
The  5-carbon compound  is  decarboxylated  bringing you back to  4-carbon oxaloacetate .  ATP  and  CO 2  are released.
 
 
Products  of the  Krebs Cycle  enter the  Final Stage  of  Aerobic Respiration
Products  of the  Krebs Cycle  enter the  Final Stage  of  Aerobic Respiration Some products are  reused,
Products  of the  Krebs Cycle  enter the  Final Stage  of  Aerobic Respiration Some products are  reused,  some are  released
Products  of the  Krebs Cycle  enter the  Final Stage  of  Aerobic Respiration Some products are  reused,  some are  released  and others are used   in the  final  stage,  oxidative phosphorylation
This is the one to blame!
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Oxidative Phosphorylation  happens via the  Electron Transport Chain.
 

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Krebs Cycle

  • 1. Also known as: Tricarboxylic acid cycle TCA cycle Kreb’s Cycle
  • 2.  
  • 3.  
  • 4. The Krebs Cycle is the Third Stage of Aerobic Respiration
  • 5. The Krebs Cycle is the Third Stage of Aerobic Respiration
  • 6. The Krebs Cycle is the Third Stage of Aerobic Respiration Takes place in the matrix of the mitochondria.
  • 7. The Krebs Cycle is the Third Stage of Aerobic Respiration Takes place in the matrix of the mitochondria. It happens once for every pyruvate molecule in glycolysis….
  • 8. The Krebs Cycle is the Third Stage of Aerobic Respiration Takes place in the matrix of the mitochondria. It happens once for every pyruvate molecule in glycolysis…. ..and so it goes round twice for every glucose molecule that enters the respiration pathway.
  • 9. Sir Hans Krebs – on his bike!
  • 10.  
  • 11. AcetylCoA (2C) from the link reaction combines with oxaloacetate (4C) to form citrate (6C). CoA is released back to the link reaction to be reused
  • 12. The 6-carbon citrate is decarboxylated – loses CO 2 – to give a 5-carbon molecule
  • 13. Both the citrate and the 5-carbon molecule formed from it are dehydrogenated (lose hydrogen ) in the cycle to reduce the coenzymes NAD and FAD
  • 14. Overall, 3 reduced NAD + and 1 reduced FAD are produced. These coenzymes not carry the hydrogen to the electron transport chain (etc)
  • 15. The 5-carbon compound is decarboxylated bringing you back to 4-carbon oxaloacetate . ATP and CO 2 are released.
  • 16.  
  • 17.  
  • 18. Products of the Krebs Cycle enter the Final Stage of Aerobic Respiration
  • 19. Products of the Krebs Cycle enter the Final Stage of Aerobic Respiration Some products are reused,
  • 20. Products of the Krebs Cycle enter the Final Stage of Aerobic Respiration Some products are reused, some are released
  • 21. Products of the Krebs Cycle enter the Final Stage of Aerobic Respiration Some products are reused, some are released and others are used in the final stage, oxidative phosphorylation
  • 22. This is the one to blame!
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28. Oxidative Phosphorylation happens via the Electron Transport Chain.
  • 29.