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Bioinformatics - Discovering the Bio Logic Of Nature

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Robert Cormia
Robert Cormia

Bioinformatics will help us discover the hidden mathematics and bio-logic of nature.

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Bioinformatics – Discovering the “Bio-Logic” of Nature Robert Cormia Foothill College
Transducing the Genome ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
‘ Energy Systems’ Before ‘Life’ ,[object Object],[object Object],[object Object],[object Object]
Energy Metabolism
“ In the Beginning” ,[object Object],[object Object],[object Object],[object Object],[object Object]
Life on the Sea Floor?
RNA Busy Before Cellular Life
The RNA World ,[object Object],[object Object],[object Object]
RNA Codons and Catalysts
RNA and DNA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Central Dogma of Life
The Genome ,[object Object],[object Object],[object Object],[object Object]
 
DNA at Transcription
The Proteome ,[object Object],[object Object],[object Object],[object Object],[object Object]
Rubisco Protein – Photosynthesis
RAD Protein Complex
Number of Genes vs. Time
What is Bioinformatics? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Internet Technologies CPU Networking Data Storage Data Mining Grid Computing Storage Area Networks
Bioinformatics Technologies Informatics IT / Networking Molecular Biology Data Modeling Computational Biology Genomic Databases
A Tool for Biotechnology ,[object Object],[object Object],[object Object],[object Object]
From Data to Knowledge
DNA Sequencing
DNA Sequencing ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DNA Sequencing http://www.accessexcellence.org
Gel Enhanced Staining
DNA Micro Arrays ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Microarray Output Screen
Microarray Output
Partnering with Pharma ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pharma and Biotech
Drug Discovery ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Drug Development Process
Drug Discovery
“ Pharmaco Genomics” ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pharmaco Genomics
One Genome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Terra Genoma
Molecular Networks ,[object Object],[object Object],[object Object],[object Object],[object Object]
Gene Regulatory Networks
 
Pathway Kinetics
Gene Regulatory Network
Bioinformatics Tools ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NCBI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
NCBI Resources
Retroviruses
BLAST ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Swiss-Prot ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ExPASy ,[object Object],[object Object],[object Object],[object Object]
PROSITE - Database of Protein Families and Domains
Structure Analysis
Protein Data Bank ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
PIR ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Pfam ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
The Grand Challenge
The Technology Roadmap ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Convergence of Biotech & Pharma ,[object Object],[object Object],[object Object],[object Object],[object Object]
Mouse Genome
 
Gene Therapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Labeling Active Genes Along Chromosomes
Transgenic Species
Designer Flies – Is Blue Cool?
Your Own Private Genome
Surfing the Genome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Contact Information ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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