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Dissertation Topics Covered in the Molecular and Cellular Basics of Cancer
and Development of Target-Specific Therapeutics- Cancer/Oncology
Dr. Nancy Agens, Head,
Technical Operations, Pubrica
sales@pubrica.com
In Brief
Researching cancer and its therapeutics is
an important tool for cancer studies and
medical writing services. The important
topics to be covered while writing a thesis
for cancer and its therapeutics are
discussed in scientific medical writing.
Pubrica is here to help with the easy
scientific medical writing about cancer
research and its therapeutics.
Keywords: Medical writing services,
Scientific Medical writing, services,
Scientific Medical writing companies,
medical writing solutions, regulatory
medical writing, scientific medical writing,
medical writing help, plagiarism
correction,
I. INTRODUCTION
Cancer is one of the life-threatening
diseases, responsible for the mortality rate of
0.13% of the world's population. It is
essential to perform research in the field of
cancer to overcome the emergency demand
to control the death rate of cancer. The
cancer research mainly has done to analyze
the risk, to know the type of cancer, to study
about the therapeutics etc with the help of
medical writing solutions. The first and
foremost essential knowledge to perform
cancer research for a scientist is to know
about the cellular basics of cancer
development. Once after attaining
knowledge, the researcher should submit a
thesis about his work. Here are a few
molecular and cellular basics about
cancer/oncology.
II. TOPICS COVERED IN MOLECULAR
BASICS OF CANCER
 Stability of a cell
 Instable gene
 Oncogenesis
 Suppressor genes for tumour
 The growth phase of tumour
 Angiogenesis
 Metastasis and model systems
 Therapeutics
Stability of a cell
The most common cause of cancer is an
undefined mass of cell growth. It is essential

2. Copyright © 2020 pubrica. All rights reserved 2
to check the stability of a DNA inside the
cell during the replication, transcription and
translation. Also, the DNA polymerase
enzyme is the reason for the correct
nucleotide activity. The above-mentioned
are the basics of cell functioning. Whenever
there is a problem in cell functioning, it may
lead to cell damage.
Instable gene
The cell damage can lead to genetic
instability. This process will change the
structure of DNA and causes mutations and
cancer. It will lead to the carcinogens to
easily rupture the cellular metabolic process.
This unstable gene leads to oncogenesis.
Oncogenesis
Oncogenesis is the process of transformation
of normal cells to cancer cells.
 Activation of oncogene
 Cell division takes place in an
unmanageable manner
Tumour suppressor genes
The tumour suppressor genes stop
functioning with inactivation of two alleles
during oncogenesis. It will mislead the cell
signalling pathways. For a non-cancerous
cell, a TSG inhibit the growth of cancer.
Hence it is called as the caretakers of the
body.
The growth phase of tumour
The forementioned oncogene and TSG
function will lead to decisive variations in
cellular growth. This tumour cells will
develop into cancer cells by shifting the
equilibrium between apoptosis and
proliferation of excessive cell growth. There
will be a disturbance in the cell cycle
pathways during this growth phase.
Angiogenesis
The tumour cells need oxygen and nutrients
supply from the blood. It will be obtained by
passing the chemical signals to the blood
vessels. However, there are several anti-
angiogenesis drugs to inhibit this process.
Metastasis and model systems
Metastasis is the process, where cancer cells
explore into foreign sites, leaving their
prime site. In the next stage of metastasis,
the cancer cells enter into the lymphatic
organs and bloodstream, that leads to cancer
death.
There are certain model systems to study the
characterization of a phenotype and
genotype. All the models should explain
using medical writing help.
Therapeutics
The need for cancer studies is mainly to
access treatment. Scientists have developed
many therapeutic agents for cancer studies
but it is still in vain to cure a certain type of
cancer especially blood cancer. The cancer
treatment will have both the advantages and
disadvantages depending upon the body
condition of a patient. There is no particular
treatment available for cancer. Out of all
chemotherapy and drug treatment is the
most common therapeutics for cancer
treatment. Drug treatment is less toxic
comparatively.
The above-mentioned passages are the
topics to be discussed while doing a
dissertation in cancer studies. It will ample
information about the entry of cancer cells
and the phases of cancer at a molecular level
in our body. Medical writing solutions are
there to complete the dissertation of topics
of basic cellular level of cancer.

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III. CONCLUSION
Pubrica has given the details for the basic
level cancer study research works. It will be
helpful for the researchers to develop a
vaccine or medicine that inhibits cancer. The
cancer study dissertation can be done with
the help of medical writing solutions and
services.These basics will also help to do
evaluations in future cancer studies. This
article is fully checked with plagiarism
correction and will be analysed by scientific
writing companies.
REFERENCES
1. Knisely, A., Wu, J., Kaplan, S. J., Zhou, Z. N.,
Melamed, A., Tergas, A. I., ... &Hershman, D. L.
(2020). Coronavirus Spectrum Infections (COVID-19,
MERS, SARS) in Cancer Patients: A Systematic
Review of the Literature. Cancer Investigation, (just-
accepted), 1-23.
2. Wang, L. H., Wu, C. F., Rajasekaran, N., & Shin, Y.
K. (2018). Loss of tumour suppressor gene function in
human cancer: An overview. Cellular Physiology and
Biochemistry, 51(6), 2647-2693.
3. Yin, H., Qu, J., Peng, Q., &Gan, R. (2019). Molecular
mechanisms of EBV-driven cell cycle progression and
oncogenesis. Medical microbiology and
immunology, 208(5), 573-583.
4. Zearmal, S., & Allen, K. (2019). 117 Qualitative
study: exploring the views of cancer researchers
surrounding Brexit and its impact on their work.