Honored to be invited to talk about our role in enabling innovation in digital healthcare at recently held CRC Penang Research Day 2018, a program under Ministry of Health, Malaysia on sharing findings of research in public healthcare.

1. Spearheading Health Innovation with
Internet of Things and Big Data
“Artificial Intelligence in Medical Care”
Penang CRC Research Day
13th Sep, 2018

2. Collaboration
Talent
R&D
Incorporated in 2011,
an Industry-led catalyst for the growth of Malaysia’s
Electrical & Electronic industry.
CREST accelerates economic growth by driving collaboration
between the Industry, Academia and Government.
CREST sparks a vibrant
R&D ecosystem by spearheading activities
in 3 key areas;
R&D, Talent Development and Commercialization.
Our Founding & Core Members, Govt. Ex-Officio

3. CREST Board – Balance between Industry, Academia and Government
Industry
Govt. Inst.
Academia
Director
Dr David Lacey
(OSRAM)
Director
En. Farid Wajidi
Northern Corridor
Implementation
Authority (NCIA)
Chairman
Dato’ Azman Mahmud
Chief Executive Officer
Malaysia Investment
Development Authority
(MIDA)
Director
Hamdan Abdul Majeed
(Khazanah)
Director
Tan Teong Khin
(Clarion)
Director
Eric Chan
(INTEL)
Director
Firdaus Abdullah
(Silterra)
Director
Professor
Datuk
Dr. Asma
Ismail (USM)
Dato’ Dr. Mohd Sofi Bin Osman
(previously with AMD, Altera,
Intel)
Dato’ Ooi Boon Chye
(Broadcomm)
Dr Hari Narayanan
A/L P Ondiveeran
(previously Motorola Solutions)
BoardMembers
Advisors

4. Enable Growth in Emerging Markets
Leveraging Our Capabilities in E&E
LED & Solid
State Lighting
Embedded
System & IoT
Adv. Materials
& Packaging
Industry
4.0
Drones &
Autonomous
Vehicle
IC Design, Test
& Validation
Commercialisation
Talent Development
Collaborative R&D
Our Core Areas:
Our Current Focus Areas
* Not limited to areas shown; revisit and redefine every 2-3 years based on market needs and trends
Connected Healthcare
Precision Farming
Future Transportation
Digital Manufacturing
Smart
Sustainable Living
Since 2015

5. Our Internet of Things (IoTs) journey starts with Industry-
Academia-Government Forum
22nd Apr 2014
CREST-Gartner IoT Workshop
•IoT business insights sharing by
Gartner
•Captains of Industry from E&E
•Healthcare Cluster formed with
Kontron as industry lead
28th Apr
Technical exchange
between Cambridge
University & Healthcare
Cluster members
8th May
Connected Healthcare
Cluster Vision, Strategic
Thrusts formulated
•Division of cluster into 3 major
sub-groups
•Insights
•Technology
•Regulatory/Policy
14-15th May
National IoT Blue-Print
TWG workshop
•National Healthcare IoT TWG
formed
•Expanded cluster members to
> 36 organisations
•CREST helps define the
National IoT Blueprint for
Healthcare vertical
Sep 2014
• iTransport cluster,
kicked-off 9 September
2014
• Motorola Solutions as
industry lead
Connected Healthcare
• Selected as 1 of 4 iconic
projects for the National
Internet of Things (IoTs)
Strategic Roadmap Initiatives
29 Jan 2015
ICDC Research Lab

6. Which Markets do we put our focus on?
5 Prioritized Market Verticals; voted by the industry, academia and government collaborators
² Drive technology development to innovate novel solutions for prioritized markets
² Develop solutions for digital mobile healthcare
² Create opportunities for SMEs and Start-Ups to
IoTs
Connected
Healthcare
iTransport
(Automotive /
Transportation)
Smart Cities
Retail
Manufacturing

7. 4th Industrial Revolution and Emerging
Markets to be impacted by Digitalization
Connected Healthcare
Precision Farming
Future Transportation
Digital Manufacturing
Smart Sustainable Living
FinTech

8. With Digitalization Comes the Disruption !!!
Biggest supplier of books, e-books does not publish any book
Biggest taxi company does not own any car
Largest hotel chain does not own any hotel
Largest education provider
does not have its own teachers,
content nor campusMOOC

9. What do these companies, their products and/or
services have in common?
Connecting MANY buyers/users to MANYsellers/providers
Lowering the COST, TIME for buyers/users
to SELECT, PURCHASE products/services
Delivering to people BEST VALUE for buyers’/users’ MONEY
DEMOCRATIZED, DISTRIBUTED, DECENTRALIZED

10. Why the Focus on Healthcare?
Let’s validate our findings with the relevant authority

11. The Case for Healthcare (in Malaysia context)
http://kpkesihatan.com/2015/08/06/full-text-of-dg-of-healths-opening-address-at-the-1st-malaysian-telemedicine-conference-2015/
The current (healthcare) system may not be sustainable in the
long term, with an ageing population, increase in chronic diseases
and rapid rise in health expenditure and high out-of-pocket (OOP)
spending. The total health expenditure as a percentage of GDP has
increased from RM8,303 million (2.95%) in 1997 to reach
RM44,748 million (4.53%) in 2013. In comparing public to private
financing for health, the ratio has been constant at 52+% for public to
47+% over the period of 1997 to 2013. In 2013, of the total private
health expenditure, 81.13% was out-of-pocket spending increasing the
risk of catastrophic health expenditure… Dato Dr Noor Hisham Abdullah,
Director General of Health Malaysia
Same Challenges in US, Europe, Japan etc.

12. Where do we focus in driving Digital Healthcare?
Disease-centric Use Cases
Devices
University+IndustryPartnershipsNCD-CVS
University+IndustryPartnershipsNCD-Diabetic
University+IndustryPartnershipsGrowth&Dev.
University+IndustryPartnershipsRemoteElderlyCare
University+IndustryPartnershipsRehabilitation
University+IndustryPartnershipsCD-Dengue
University+IndustryPartnershipsWellness
University+IndustryPartnershipsCD-Malaria
horizontal middleware & vertical business application
Sensors
Energy Management/Embedded Sys
Adv Wireless Communication
Common Library
Reference Model
Common Architecture
Patient Healthcare Record Database
Data Analytics
Aligned with MoH pain points as
communicated by DG of Health
in May 2014

13. Director General of Health’s View on Future of Public Health
The future of healthcare is
Digitized, Decentralized and Distributed
3rd April,
2018:
Refined Our
Strategy on
Better
Healthcare
to All

14. * not limited to devices shown here
HIS-KKM
Driving Digital
Healthcare via
Digitised
Decentralised
Distributed
Services
3D Healthcare

15. Healthcare to U Disruption is happening Now!
15

16. Mooted and
Designed in
Australia
Developed and
Manufactured in
Malaysia
Clinically
Researched and
FDA Approved in
US
The world first
AI enabled stethoscope
Dr Nayyar Hussain MD, Inventor of
Stethee and CREST Collaborator
Realizing 3D Healthcare Services
M3DICINE Pty Ltd.
MIT
Mayo Clinic
CREST & Industry Partner
MoH, CRC, MIDA

17. Sensionics Long-Lasting Glucose Monitoring Sensor
Encased in a biocompatible
material, the sensor utilizes a
patented fluorescent, glucose
indicating polymer technology to
measure glucose in the
interstitial fluid
The measurement and display of
glucose values is done
automatically, without the need
for user intervention.
“No more prick your finger twice a day”

18. Manish Jain, SlideShare Presentation
Why Big Data and AI/Analytics ?

19. Manish Jain, SlideShare Presentation

20. Manish Jain, SlideShare Presentation

21. The global Internet of Things (IoT) healthcare market is estimated
to grow from USD 32.4 Billion in 2015 to USD 163.2 Billion by 2020,
at a CAGR of 38.1 % during the forecast period (2015 to 2020).
Source: marketsandmarkets.com, October 2015, Report Code: TC 3847
Key market players in healthcare analytics include IBM Corporation (U.S.), SAS Institute, Inc. (U.S.), Optum, Inc. (U.S.), Truven Health Analytics Inc. (U.S.),
Cerner Corporation (U.S.), McKesson Corporation (U.S.), Verisk Analytics, Inc. (U.S.), Oracle Corporation (U.S.), Allscripts Health Solutions (U.S.),
MedeAnalytics (U.S.), Inovalon, Inc. (U.S.) and Health Catalyst (U.S.).
Internet
1. “The Intelligent Devices / Things”
2. Data Analytics & Artificial Intelligence
3.End-to-EndDigitalHealthSolutions
“The Healthcare Analytics Market is
expected to reach $18.7 Billion by 2020
from $5.8 Billion in 2015”,
Source:: marketsandmarkets.com, July 2015 Report Code: HIT
2180.
v Signal processing
v Data Cleansing & semantic Interoperability
v Data analysis algorithms & modelling
v Cognitive computing- pattern recognition, AI and deep
learning
v Automated robots for patient monitoring & diagnosis
v Secure cloud based medical data storage & management
best practices
Medical Data &
Artificial Intelligence
(MDAI)

22. How do we trigger hospital, doctors and caretakers
when someone we love is at the brink of potential heart
attack? And save lives?
Key Focus
Wearable Printed ECG Patch
Printing
nano-material
on Flexible
material
Electrical
Properties
Optimization
Wireless
transmission
characteristic
Wearable IOT
system
Clinical
testing
Background
• Body sensor networks is key to wireless health revolution.
• EEG and ECG limited by wet contact electrodes.
Scope
• Technologies, material, wireless connectivity, IOT, human,
clinical factor in a medical wearable.
Explored Solution
• Printed Area Electronics flexible ‘patch’ with the wireless
sensor towards medical monitoring application
Collaborators:A collaboration between local digital
healthcare startup, local manufacturer,
Institut Jantung Negara and UTM
Cardiovascular Eng. Centre;
targeting user trial by end 2018 !!!

23. How do we provide real time, in the field
detection of food pathogens like e-coli and
salmonella in chicken sold at “pasar malam”
etc, so we can prevent outbreak of various
diseases? Can we reduce test time from 3
weeks to 3 minutes?

24. 24
How can we better predict and trigger potential dengue alert
based on actual mosquito population data combined with
personal health record and weather patterns ?

25. How do we customize rehabilitation regime using Robotic
Assessment and Gamification for Stroke Patients?
• Stroke rehabilitations rely mainly on
manual labour and lack objective
assessment
Background
• Assessment device with rehabilitation
capability for upper limbs
• Tele-monitoring platform to allow remote
monitoring of patients progress
Scope
• CR2-Haptic Robot: Immersive
Technologies for Rehabilitation Training
Solution

26. Driving Innovation in Healthcare at the Intersection of
Biochemistry, Electronic and ICT
Bio-Sensors
Inviting Researchers
and Industry in
Biotechnology to better
serve the medical and
healthcare sector

27. Introducing a Quintuple Helix Model
in Driving Digital Healthcare Innovation
IndustryAcademia
Government
Civil Society
(Patients)
Society
Healthcare
Challenges
Triple Helix
Quadruple Helix
Quintuple Helix
* Carayannis et al. Journal of Innovation and Entrepreneurship 2012, 1:2
http://www.innovation-entrepreneurship.com/content/1/1/2
”The Quintuple Helix innovation model: global warming as a challenge
and driver for innovation”

28. Want to Help Solve Digital
Healthcare Challenges?

29. Open and Targeted R&D
New Product Innovation
(Including bringing VCs, other Investors)
Prototype, MVP, Validation Ecosystem & biz enhancement
Compact
Rehab
Robot
Atrial
Fibrillation
Detection
Algorithm
Printable
ECG
Patch
Early
Breast
Cancer
Detection
Salmonell,
E-Coli,
Listeria
PoC
System
Wide
Body
Antenna
Patient
Health
Record
Wearable
Power
Mgmt
Wireless
energy &
data
transfer
Stretchable
Polymer &
Ink
Aedes
Detection
System
Kinetic
energy
harvester
MyCapsule
Hypoband
CR-2
Onitor
MiniHeartCatcher
12 R&D projects
3 MNCs, 5 SMEs, 2 Start-ups,
12 Universities, Public & Private Hospitals
Join CREST Digital Healthcare Cluster and Collaborate to Innovate
Technology Readiness Level
1-3
4-6 7-9 Commercialization Scaling and beyond

30. Who to contact?
Aida Basri
Program Director, Digital Healthcare
Collaborative Research in Engineering, Science & Technology (CREST)
Aida@crest.my
013-920-2011

31. Collaborative Research in Engineering Science & Technology (CREST) Center
www.crest.my
norazmialias@crest.my