Mais conteúdo relacionado Semelhante a Cns infections (20) Mais de Kamran Afzal, PhD. (20) Cns infections13. Post surgical procedures OR Post cranial/spinal trauma Enterobacteriaceae Pseudomonas aeruginosa Staphylococcus aureus Streptococcus pneumoniae Persistant CSF leak Streptococcus pneumoniae 27. CSF Routine Examination GRAM NEGATIVE COCCI GRAM POSITIVE COCCI GRAM NEGATIVE RODS GRAM POSITIVE RODS GRAM STAIN 28. CSF Evaluation Normal Bacterial Viral TB Cells 0-5 >1000 <1000 <500 Polymorphs 0 Predominate Early +/- increased Lymphocytes 5 Low Predominate Increased Glucose 60-80 Decreased ++ Normal Decreased+ CSF : plasma Glucose ratio 66% <40% Normal < 30% Protein 5-40 Increased+++ +/- Increased Increased+ Culture Negative Positive Negative Positive (MTB) 47. Treatment Disease Dose Duration HIV neg. Amphotericin 0.7MKD +flucytosine 100MKD +fluconazole 400mg/d 2 wk 10 wk Amphotericin 0.7MKD +flucytosine 100MKD 10 wk HIV pos. induction Amphotericin 0.7MKD +flucytosine 100MKD +fluconazole 400mg/d 2 wk 10 wk maintanance Fluconazole 400 mg/d 48. Protozoa Protozoan Disease Toxoplasma gondii Associated with congenital defects and AIDS African Trypanosomes African Sleeping Sickness Plasmodium falciparum Cerebral Malaria Entamoeba histolytica Rare invasion of the brain Acanthamoeba Rare cases Notas do Editor RBC – traumatic vs CNS bleeding. After a few hours, CSF will be xanthrochromic; if traumatic it will be clear with centrifugation. Latex agglutination has high false negative rate.