Bacillus anthracis

Bacillus anthracis Dr Kamran Afzal Asst Prof Microbiology

Clinically Important GPRs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Identity of Genus Bacillus ,[object Object],[object Object],[object Object],[object Object]

Species ,[object Object],[object Object],[object Object],[object Object]

Bacillus anthracis ,[object Object],[object Object],[object Object],[object Object],[object Object]

Virulence Factors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Staining ,[object Object],[object Object],[object Object],[object Object]

Culture ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Endospore ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Anthrax ,[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Who gets it? ,[object Object],[object Object],[object Object],[object Object]

Epidemiology ,[object Object],[object Object],[object Object],[object Object]

Pathogenesis ,[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

Lab Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Presumptive Identification Clinical specimen (blood, CSF, etc.) Isolate on BA Colony morphology No hemolysis Non motile Spores Gram stain Malachite green Gram stain Capsule production

Confirmatory Identification Isolate Phage lysis Capsule Bicarbonate media Horse blood (McFadyean Stain) (McFadyean stain India ink stain) DFA Capsule antigen Cell wall

Rapid Detection Methods ,[object Object],[object Object],[object Object]

Radiological Diagnosis ,[object Object],[object Object],[object Object],[object Object]

Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Post-Exposure Prophylaxis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Case Study ,[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object]

As Biological Warfare Agent ,[object Object]

Benefits of Using Anthrax as a BW ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pakistan’s Experience of Bioterrorism ,[object Object],[object Object],[object Object],[object Object],[object Object]

Bacillus anthracis

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