1. Karyotyping

2. What is a Karyotype?
A set of chromosomes.
 46 chromosomes in a human
karyotype (23 pairs).

3. Amniocentesis
 Method for
obtaining fetal
cells.
 Chromosomes
can be obtained
from cells.

4. When Should Amniocentesis
Be Done?
 This is a “risky” procedure.
 Should be performed on women
who:
a) Are in their mid 30’s or older.
b) Have had a previous child with
a chromosomal defect.

5. Chromosome Spread

6. Karyotype

7. Patient Name:

8. What can be determined
from looking at a karyotype?
1. Sex of the individual.
2. Chromosomal mutations (abberations)
a) Monosomy
b) Trisomy
c) Deletions
***Depending which chromosome has the
mutation, this determines the disorder…