Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Diarrhoea prevention and control
1.
2. CONTENTS
INTRODUCTION
PROBLEM - WORLD
- INDIA
CLASSIFICATION
CAUSES
DEHYDRATION
CLASSIFICATION OF DEHYDRATION
PRINCIPLES OF MANAGEMENT
4. INTRODUCTION
Diarrhoea is defined as passage of unusually loose or
watery stools usually at least three times in a 24 hour
period. (WHO)
However it is the consistency of the stools rather than
the number that is more important.
Passage of even one large watery stool in young child is
diarrhoea.
Frequent passage of normal stool is no diarrhoea.
5. 6-12 months of age are affected severely & account for
high mortality.
Dehydration occurs when water & salts are not replaced
adequately -may lead to shock & death.
Diarrhoea also produces under nutrition and growth
failure.
Diarrhoeal disease constitute one of the important
“nutritional leak” in young children.
Even a brief episode of diarrhoea leads to the loss of 1-2
% of body weight in children.
INTRODUCTION
6. MAGNITUDE OF THE PROBLEM: WORLD
Diarrhoeal disease is the 2nd leading cause of death in
children under 5 yrs of age.
Globally, there are about 2 Bn cases of diarrhoeal disease
every yr.
Diarrhoeal disease kills 1.5 Mn children every yr.
African and South-East Asian regions together account
for nearly 78% of them.
India alone contributes about 20% of all global under-5
diarrhoeal deaths.
It is both preventable and treatable.
7. In developing countries, children under three years old
experience on an average three episodes of diarrhoea
every year
Each episode deprives the child of the nutrition
necessary for growth
As a result, diarrhoea is a major cause of malnutrition,
and malnourished children are more likely to fall ill
from diarrhoea. It makes a vicious cycle
MAGNITUDE OF THE PROBLEM: WORLD
8. ARIs*
19%
Diarrhoea*
19%
Measles*
Malaria*
5%
Other
32%
Perinatal
18%
Malnutrition*
54%
* Based on data taken from The Global Burden of Disease 1996, edited by Murray CJL and
Lopez AD, and Epidemiologic evidence for a potentiating effect of malnutrition on child
mortality, Pelletier DL, Frongillo EA and Habicht JP, AmJ Public Health 1993;83:1130-1133
7%
Leading causes of deaths in children under 5 yrs
9. CAUSES OF DEATH IN CHILDREN IN
DEVELOPING COUNTRIES, 2002* (in thousands)
Rank Cause Numbers deaths %
1. Perinatal conditions 2375 23.1
2. Lower resp. inf. 1856 18.1
3. Diarrhoeal Diseases 1566 15.2
4. malaria 1098 10.7
5. Measles 511 5.4
6. Congenital anomalies 386 3.8
7. HIV/AIDS 370 3.6
8. Pertussis 301 2.9
9 Tetanus 185 1.8
10. PEM 13 1.3
11. TOTAL 10263 100
* Source: World Health Report 2003
10. MAGNITUDE OF THE PROBLEM: INDIA
NFHS-3 data projected morbidity profile of
children <3yr:-
Fever - 27%
Acute respiratory infections -17%
Diarrhoea -13%
Underweight - 43%
11. Classification of Diarrhoea
Based on clinical syndromes
Acute watery diarrhoea
Dysentery
Persistent diarrhoea
12. Acute watery diarrhoea
Start suddenly
Most episodes recover or self limiting within 3-7 days.
These may last up to 14 days
>75% of all episodes are of acute watery diarrhoea.
Dysentery
Diarrhoea with visible blood & mucus in the faeces.
Also abdominal cramps, fever, anorexia and rapid weight
loss.
13. Persistent Diarrhoea
Diarrhoea which lasts for > 14 days
Incidence is around 5% i.e. 5% of acute diarrhoea
may persist beyond 2 weeks
14. ORGANISMS PRODUCES ACUTE WATERY DIARRHOEA
Bacteria- Account 1/3rd of total causes
E. Coli
V. Cholera
V. Parahaemolyticus
Shigella- bloody diarrhoea or dysentery
S. Typhi
Staph. Aureus
Clostridium perfringens
E. coli
15. Viruses- 1/3rd of total causes
Rotavirus
Astroviruses
Calciviruses
Coronaviruses
Norwalk group viruses
Enteroviruses
Rotavirus causes 15-25% diarrhoea cases in developing
countries
Rotavirus
17. RISK FACTORS OF DIARRHOEA
Bottle fed babies have more chances to develop
diarrhoea because of unclean bottles
Flies can also bring germs to uncovered food
Drinking contaminated water
Unclean food, milk, unclean hands & unclean utensils
19. SIGNS OF DEHYDRATION & TREATMENT PLAN
Reflected by the following signs in addition to above
signs
Lethargic or unconscious , difficult to wake
Floppy
Refusal for feed/breastfeed in young infant and
Unable to drink.
Signs Classification of
dehydration
Treatment
No signs of
dehydration
No dehydration Follow Plan A
Two of the
following signs
Some dehydration Follow plan B
•Restless, irritable
•Sunken eyes
•Tear absent
•Dry mouth &tongue
•Skin goes slowly
•Thirst, drinks
eagerly
20. SIGNS OF DEHYDRATION & TREATMENT PLAN
Reflected by the following signs in addition to above
signs
Lethargic or unconscious , difficult to wake
Floppy
Refusal for feed/breastfeed in young infant and
Unable to drink.
Signs Classification of
dehydration
Treatment
Two of the
following signs
Severe
dehydration
Follow plan C
•Unconcious
•Floppy
•Refusal to feed
•Unable to drink
•Very sunken eyes
•Skin goes back
very slowly
21. PRINCIPLES OF MANAGEMENT OF
ACUTE DIARRHOEA
In early stages of diarrhoea when ORS packets are not
immediately available, HAF is given and continue
feeding
CONTINUE BREAST FEEDING
BUT
-Soft drinks
-Sweetened fruit juices
-Sweetened tea should not be used.
These have high osmolarity and can lead to worsening of
diarrhoea and further leading to dehydration.
22.
23. PRINCIPLES OF MANAGEMENT OF
ACUTE DIARRHOEA
Rationale use of drugs
ORS is the drug of choice for all cases of
diarrhoea
It is life saving when used timely, in adequate
quantities
Only a small proportion of cases of diarrhoea
(dysentery, cholera and associated illnesses) need
specific antimicrobials
24. PRINCIPLES OF MANAGEMENT OF
ACUTE DIARRHOEA
Drugs Like
- Anti-motility drugs
- Stimulants
- Steroids
MUST NOT BE USED
as they provide pseudo sense of protection among
mothers and distract their attention from correct
treatment
Their marketing has been banned in India
25. ORAL REHYDRATION SALT(ORS)
It is a balanced mixture of glucose and electrolytes
Almost all deaths from diarrhoea can be prevented by
ORS
MECHANISM OF ACTION
Sodium promotes absorption of water from the
intestine
Glucose promotes the absorption of sodium and water
from the intestine
26. Cases with No Signs of Dehydration
Plan A
In early stages, when fluid loss is <5% of the body
weight, children may not show any clinical signs of
dehydration
Give HAF or ORS
Plan A involves counselling the child's mother about
the 3 Rules of Home treatment.
GIVE EXTRA FLUID (as much as the child will take)
CONTINUE FEEDING
WHEN TO RETURN
27. Cases with signs of Some Dehydration
Children who have dehydration should be kept under
observation in the hospital/ health center for a few
hours and given prepared ORS solution during the
period
Purpose:
Correct fluid deficit and ongoing fluid losses
28. Cases with signs of Some Dehydration
Plan-B
REHYDRATION THERAPY
Amount of ORS to be given in first 4 hrs
Age < 4
months
4 -12
months
12m- 2 yrs 2-6 yrs
Wt (kg) < 6 6 - < 10 10 - <12 12 - 19
ORS(ml) 200-400 400-700 700-900 900-1400
Glass(No.) 1 - 2 2 - 3 3 – 4 4 - 7
29. Use the child’s age only when we do not know the
weight.
The approximate amount of ORS required (in ml) can
also be calculated by multiplying the child’s weight (in
kg) × 75
For infants who are not breastfed, also give 100-200 ml
of clean water during this period. The breastmilk and
water will help prevent hypernatraemia in infants.
Show the mother how to give ORS solution
After 4 hours
Reassess and classify the child for dehydration
Select the appropriate plan to continue treatment
Begin feeding the child in clinic
Cases with signs of Some Dehydration
30. Cases with signs of severe dehydration
Plan-C
1% diarrhoea may develop severe dehydration.
Children with severe dehydration must be admitted.
Child is rehydrated quickly by using I/V infusion.
I/V infusions recommended :
R/L solution
N/S when R/L is not available
1/2 N/S with 5% dextrose is acceptable
Plain glucose is unsuitable solution
31. Plan-C
Rate & Quantities of I/V infusion for severe dehydration
Age 30 ml/kg 70 ml/kg 100 ml/kg
Infant First hour Next 5 hrs 6 hrs
Older
children
First 30
mins
Next 2.5 hrs 3 hrs
Cases with signs of severe dehydration
32. Plan-C
Reassess the infant every 15-30 min. until a strong radial
pulse is present.
Thereafter, reassess the infant by skin pinch and level of
consciousness at least every 1-hour
Also give ORS (about 5 ml/kg/hour) as soon as the
infant can drink: usually after 3-4 hours
Reassess the infant after 6 hours & classify dehydration
then choose the appropriate plan (A,B, or C) to continue
treatment
Cases with signs of severe dehydration
33. After signs of severe dehydration disappear & child is
able to drink, further therapy should be continued with
ORS as per plan A or B
Before the mother leaves the hospital two packets of
ORS must be given.
Cases with signs of severe dehydration
34. 20 mg per day of Zn supplementation for 14
days starting as early as possible after onset of
diarrhoea
10 mg per day for infants 2-6 months
WHO/UNICEF Joint statement (2001),
IAP 2003, GOI 2007
Recommendations for use of zinc in
clinical management of acute diarrhoea :
35. Factors Suggesting
Zinc Deficiency in a Population
High phytate staple foods
Low intake of “flesh” food
High prevalence of stunting
High rate of diarrhoea
Nutritional iron deficiency
37. Probiotics:
- means "for life" and is currently used
to name bacteria associated with
beneficial effects for humans and
animals.
Coined in 1960 to name substances
which promoted the growth of other
organisms.
38. Effect of probiotics in diarrhoea-
The strongest evidence of a beneficial
effect has been for the following
probiotics - Lactobacillus rhamnosus
GG and Bifidobacterium lactis BB-12
These probiotics are effective for both
treatment and prevention of acute
diarrhoea caused mainly by rotavirus
in children
Antibiotic associated diarrhoea has
also been found to respond when
probiotics have been used as
prophylaxis and also for therapy
39. Probiotic strains
- Can inhibit the growth and adhesion of a
range of entero-pathogens
- Animal studies have indicated beneficial
effect in Salmonella.
Traveler's diarrhoea due to bacterial
infection has been benefited
The most highlighted beneficial effect of
probiotics has been on acute diarrhoea
caused by rotavirus in children.
41. FEEDING IN DIARRHOEA
Children should continue to be fed during diarrhoea.
Milk should not be diluted with water during any phase
of acute diarrhoea.
Milk can also be given as milk cereal mixture e.g. dalia,
milk-rice mixture.
This technique reduces the lactose load & preserving
energy density.
42. To make foods-energy dense some of preparation are:-
- Khichri with oil
- Rice with curd & sugar
- Mashed banana with milk or curd
- Mashed potatoes with oil.
Breast feeding should be continued uninterrupted even
during rehydration with ORS.
FEEDING IN DIARRHOEA
43. Dysentery
Requires antibiotic therapy
However if there is only mucus, child should be treated
as for acute diarrhoea without antibiotics
Shigellae responds to cotrimoxazole
1 Tab BD x 5 days for < 2 months.
2 Tab BD x 5 days for 2-12 months.
3 Tab BD x 5 days for 1-5 years of age.
OR
Nalidixic acid 55 mg/kg/day in 4 doses x 5 days.
44. Cholera:-
Antibiotics used are:
Doxycycline- 6 mg/kg/day a single dose x 3 days
or
Tetracyline - 50 mg/kg/day 4 doses x 3 days
or
Erythromycin -30 mg/kg/day 3 doses x 3 days.
Acute Amoebiasis:
Metronidazole -30 mg./kg/ day 3 doses x 5-10 days.
Acute Giardiasis:
Metronidozole -15 mg/kg/day 3 doses x 5days.
45. The treatment for persistent diarrhoea requires special
feeding and giving vitamin A and zinc
The mother of a child with persistent diarrhoea will be
advised on feeding her child
Diet: - Cereals + legumes
- Cereal+ milk or curd or some oil are
considered good foods.
- Eggs (boiled & mashed added to the basic
cereals).
In case, if diarrhoea persists after 6 days of treatment,
these children should be admitted for further treatment.
Persistent diarrhoea:-
46. Exclusive Breast Feeding
Bottle feeding should be avoided
Wash Hand
Eat clean Food
Drink clean water
Immunization e.g. Measles, Rota virus
Vit. A - Prophylactic doses
Nutrition
Prevention of Diarrhoea:
47. Rota virus vaccination
Rotashield vaccine -1999
Withdrawn because of its association with
intussuscption
Two new oral, live attenuated rotavirus vaccines were
licensed in 2006 with very good safety and efficacy
The first dose administered between ages 6-10 weeks .
subsequent doses at intervals 4-10 weeks.
Vaccination should not be initiated before 6weeks and
after 12 weeks of age.
All doses should be administered before 32 weeks.
48. Rota Rix vaccine Rota Teq vaccine
Oral, live attenuated
Oral, live attenuated,
pentavalent vaccine. Contains 5
live reassortant rotaviruses
2 dose schedule
3 dose schedule
1st dose - 2 month of age at 2 month of age
2nd dose- 4 month 4 month of age
…………………………. 6 month of age
50. WHO Recommendation for Rota virus vaccination
Geneva and Seattle, June 5, 2009 — WHO has
recommended that rotavirus vaccination be included in
all national immunization programmes
The new recommendation by the WHO's Strategic
Advisory Group of Experts (SAGE),extends an earlier
recommendation made in 2005 on vaccination in the
America and Europe, where clinical trials had
demonstrated safety and efficacy in low and
intermediate mortality populations.
51. Challenges for ORT
ORT reduces mortality but does not decrease episode
duration or their consequences, such as malnutrition
Adherence to ORT is poor because caregivers want to
reduce illness duration
This leads to use of antibiotics or other treatment of no
proven value
Unfortunately, knowledge and use of appropriate home
therapies, including ORT, may be declining in some
countries
52. SEARCH FOR ADJUNCT THERAPIES
12-59 months old Indian children with zinc deficiency
had 1.5 times more diarrhoea and 3.5 times more ALRI
than non zinc deficient children.
53. NATIONAL DIARRHOEAL DISEASE CONTROL
PROGRAMME
NDDCP was launched in 1981
Main objective were reduction of mortality through
introduction of ORT.
Goals were:
Reduce diarrhoeal associated mortality in children <5
years by 30% by 1995 and by 70% by 2000 A.D.
Reducing CFR to less than 1%.
Improvement in water and sanitation facilities was the
long term goal of NDDCP
54. National ORT Programme was incepted in 1985- 86
From 1992-93 the programme has become a part of
CSSM Programme.
CSSM programme become a part of RCH programme in
1997
In RCH Programme, policy of IMCI was adopted
Strategy of IMCI was to address all children and not only
sick children
IMCI focused on life threatening illnesses-diarrhoea,
Pneumonia, Measles, Malaria etc.
NATIONAL DIARRHOEAL DISEASE CONTROL
PROGRAMME
55. Contd.
Indian version of IMCI guidelines renamed as IMNCI.
Since 2003 - DDCP included in IMNCI which includes
- Neonates of 0-7 days
- Incorporating national guidelines on
diarrhoea, ARI ,Malaria, Anaemia, Vit. A
supplementation & Immunizations.
56. STRATEGIES OF IMNCI
Ensure standard case management of diarrhoea by
training of medical and other health personnel.
Promote standard case management practices among
private practitioners through IMA and IAP.
Improve maternal knowledge on home management
and recognition of danger signs of diarrhoea for
immediate medical care.
57. Increase availability of ORS by providing free ORS
packets at health facilities and outreach depots.
Increase accessibility by marketing ORS through the
PDS and commercial outlets.
Monitor hospital based data on ORS use rate, CFR &
other parameters.
Promote exclusive breast feeding for the first 6 months,
proper weaning, infant immunization including measles
immunization and Vit A prophylaxis.
58. Case management strategy
CLASSIFICATION:
PINK :
Child needs referral ( Inpatient care)
YELLOW :
Child needs specific treatment, provide it at
home (e.g. Antibiotics, ORS)
GREEN :
Child needs no medicine, give home care
59. Limitations of IMNCI
Outpatient Facility Based
Community activities not given adequate focus
Vertical initiatives in Non IMNCI districts sorely
lacking
60. F-IMNCI
From November 2009 - IMNCI has been re -
baptized as F-IMNCI, (F -Facility) with added
component of:
Asphyxia Management and
Care of Sick new born at facility level, besides
all other components included under IMNCI
61. DIARRHOEA CAN BE PREVENTED
Promote exclusive breastfeeding
Immunization against measles
Using sanitary latrines
Keeping food and water clean
Washing hands before eating & after defecation.
62. MESSAGES:
ORS is best drink.
A child with diarrhoea needs more food and
frequent breast feeding.
A child who is recovering from diarrhoea needs an
extra meal every day for at least 2 weeks.
Medicine other than ORS should not be used
except on medical advice.
63. REFERENCES
MODULES of IMNCI 2003
K.PARK , TEXTBOOK OF COMMUNITY MEDICINE
SUNDER LAL, TEXTBOOK OF COMMUNITY
MADICINE.
HARRISONS PRINCIPLES OF INTERNAL MEDICINE
17th edition
IAP GUIDELINES FOR MANAGEMENT OF
DIARRHEA
WORLD HEALTH ORGANIZATION (WHO)
GUIDELINES ON TREATMENT OF DIARRHEA (2005