Psychiatric Manifestations In Dementia

PSYCHIATRIC MANIFESTATIONS IN DEMENTIA

Introduction ,[object Object],[object Object],[object Object],[object Object],[object Object]

Definitions ,[object Object],[object Object],[object Object],[object Object]

Mild Cognitive Impairment ,[object Object],[object Object],[object Object],[object Object],[object Object]

Mild Cognitive Impairment ,[object Object],[object Object],[object Object],[object Object]

Alzheimer's Disease- Apathy ,[object Object],[object Object],[object Object],[object Object],[object Object]

Alzheimer's Disease- Apathy ,[object Object],[object Object],[object Object],[object Object]

Alzheimer's Disease- Anxiety ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Alzheimer's Disease- Agitation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Alzheimer's Disease- Depression ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Alzheimer's Disease- Depression ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Alzheimer's Disease- Psychosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Prevalence of neuropsychiatric symptoms in MCI and AD 4 15 3 15 <1 10 20 11 1 3 MCI (n=320) Community Study % Tertiary Care Centre study % 27 14 16 Aberrant motor behaviour 38 29 27 Irritability 21 18 13 Disinhibition 51 39 27 Apathy 8 11 3 Euphoria 35 25 22 Anxiety 50 39 32 Dysphoria 34 18 30 Agitation 6 0 11 Hallucination 26 4 18 Delusion AD (n=124) MCI (n=28) AD (n=362) Symptom

Alzheimer's Disease Variants ,[object Object],[object Object],[object Object]

Dementia With Lewy Bodies ,[object Object],[object Object],[object Object]

Dementia With Lewy Bodies ,[object Object],[object Object],[object Object],[object Object]

Delusional misidentification syndromes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Frontotemporal Dementia ,[object Object],[object Object],[object Object],[object Object],[object Object]

Vascular Dementia ,[object Object],[object Object],[object Object],[object Object]

Evaluation Of Neuropsychiatric Symptoms In Demented Patients ,[object Object],[object Object],[object Object]

Evaluation Of Neuropsychiatric Symptoms In Demented Patients ,[object Object],[object Object],[object Object],[object Object],[object Object]

Behavioral Interventions ,[object Object],[object Object],[object Object],[object Object],[object Object]

Pharmacologic Interventions: Cholinesterase inhibitors ,[object Object],[object Object],[object Object],[object Object],[object Object]

Memantine ,[object Object],[object Object],[object Object],[object Object]

Antipsychotics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Antipsychotics ,[object Object],[object Object],[object Object],[object Object],[object Object]

Mood Stabilizers ,[object Object],[object Object],[object Object],Antidepressants ,[object Object],[object Object]

Pharmacotherapy of neuropsychiatric symptoms Risperidone + SSRIs/SNRIs Trazodone AChEIs SSRIs, SNRIs, BZDs SSRIs Risperidone, Quetiapine SSRIs Quetiapine, Risperidone First line Olanzepine+SSRIs/SNRIs Psychotic depression Zolpidem Insomnia/ sundowning Apathy Atypical antipsychotics Anxiety SNRIs Depression Olanzapine, Aripiprazole Aggression Quetiapine, Risperidone Agitation Olanzapine, Aripiprazole Psychosis Second line Symptom

Conclusion ,[object Object],[object Object],[object Object],[object Object]

Key Points ,[object Object],[object Object],[object Object],[object Object]

Key Points ,[object Object],[object Object],[object Object],[object Object],[object Object]

Psychiatric Manifestations In Dementia

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Psychiatric Manifestations In Dementia