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FOOD POISONING




     Dr Hemanth S Naik, BMCRI
Definition

   Illness which results from ingestion of food
    containing non-bacterial and/or bacterial
    products.




                  Dr Hemanth S Naik, BMCRI
causes

   Bacteria and toxins
   Vegetable origin
   Animal origin
   chemicals




                  Dr Hemanth S Naik, BMCRI
Bacteria and toxins
    Infection type
1.   Salmonella group
2.   Proteus
3.   Coli group
4.   Shigella
     salmonella Symptoms appear in 24 to 48 hours
     of eating meal, mainly indicates

                 Dr Hemanth S Naik, BMCRI
Bacteria and toxins
Toxic type
 Due to performed toxins in prepared food
   such as canned and preserved food.
 Eatables affected are meat, fish, egg.
 Symptoms appear within 24 hours
 More common in summer

1. Enterotoxin
2. Botulinum toxin


               Dr Hemanth S Naik, BMCRI
Botulism

   Botulismfrom Latin botulus = "sausage“, as
    bacterium often causes poisoning by growing in
    badly handled or prepared meat products.
   Toxin destroyed at 80 degrees
   Fatal dose is 0.01mg or even less
   Blocks action of acetylcholine specific to
    autonomic nervous system


                  Dr Hemanth S Naik, BMCRI
Botulism

   Incubation period –12-30 hours
   Symptoms include vomiting, constipation,
    ocular paresis, muscular weakness, subnormal
    temperature
   Mortality 25% to 100%
   Treatment – polyvalent serum



                  Dr Hemanth S Naik, BMCRI
.

Bon Vivant incident

 On July 2, 1971 the FDA released a public
 warningafter learning that a New York man had died
 and his wife had become seriously ill due to botulism after
 eating a can of the company’s Bon Vivant vichyssoise
 soup
               The FDA shut down Newark, New Jersey
 plant on July 7, 1971


                   Dr Hemanth S Naik, BMCRI
Vegetable origin

   Lathyrus sativus
   Mushrooms
   Argemona mexicana
   Lolium temulentum




                Dr Hemanth S Naik, BMCRI
Lathyrus sativus

   Grows under extreme
    conditions of famine
   B-(N)oxalyl
    aminoalanine BOAA,
    active principle
   Causes
    neurolathyrism


                 Dr Hemanth S Naik, BMCRI
Neurolathyrism
   Characterized by progressive spastic paraplegia
    with preservation of sphincters, ending in
    irreversible disability
   Back pain>weakness of legs>difficulty in
    sitting>unable to walk>spastic gait>complete
    paralysis
   Steeping the pulse in hot water and parboiling
    removes 90% of toxic amino acid


                  Dr Hemanth S Naik, BMCRI
.




Dr Hemanth S Naik, BMCRI
.




During the Spain War of Independence against Napoleon,
grasspea served as a famine food. This was the subject of one of
Francisco de Goya's famous aquatint prints titled Gracias a la
Almorta ("Thanks to the Grasspea"), depicting poor people
surviving on a porridge made from grasspea flour, one of them lying
on the floor, alreadyDr Hemanth S it. BMCRI
                      crippled by Naik,
Death cap
   Unpleasant taste
   Grows in woody
    places
   Toxins are phalloidin,
    pahllon, 13 amanatin
    which are
    cyclopeptides


                  Dr Hemanth S Naik, BMCRI
Amanita muscaria

   Have bitter taste
   Changes color on cut
    section




                 Dr Hemanth S Naik, BMCRI
Signs and symptoms

   Nausea
   Vomiting
   Diarrhoea
   Convulsions
   Collapse
   Death



                  Dr Hemanth S Naik, BMCRI
Treatment

   Antiphalloidien serum
   Atropine sulphate
   Silibin dihydrogen disaccinate sodium




                  Dr Hemanth S Naik, BMCRI
Argemona mexicana

   Species of poppy
    found mainly in
    Mexico
   Contains berberine,
    protopine,
    sanguinarine and
    dihydrosanguinarine
   seeds resemble
    mustard and used as
    adulterant    Dr Hemanth S Naik, BMCRI
Signs and symptoms

   Loss of appetite – diarrhoea
   Edema of legs – anasarca
   Vascular injuries
   Telangiectasis



            Death due to severe damage to heart

                   Dr Hemanth S Naik, BMCRI
Lolium Temulentum
   Weed grass grown in
    wheat field
   Grains similar to
    wheat
   Grains attacked by
    fungus containing
    Temuline
   Headache, muscular
    weakness, coma
                 Dr Hemanth S Naik, BMCRI
Dr Hemanth S Naik, BMCRI
Signs and symptoms

   Source – Gambierdiscus toxicus
   GI distress, hallucination and reverse of hot-cold
    sensation
   Treatment – mannitol, amitriptylline




                   Dr Hemanth S Naik, BMCRI
Scombroid poisoning

   Associated with sea
    food, stored
    improperly
   Symptoms due to
    histidine converting
    into histamine above
    60 degrees
   Allergic symptoms

                  Dr Hemanth S Naik, BMCRI
Shellfish poisoning
   GI disturbance
   Neurotoxicity
   Mutisim, memory
    loss, coma




                Dr Hemanth S Naik, BMCRI
Dr Hemanth S Naik, BMCRI

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Food poisoning

  • 1. FOOD POISONING Dr Hemanth S Naik, BMCRI
  • 2. Definition  Illness which results from ingestion of food containing non-bacterial and/or bacterial products. Dr Hemanth S Naik, BMCRI
  • 3. causes  Bacteria and toxins  Vegetable origin  Animal origin  chemicals Dr Hemanth S Naik, BMCRI
  • 4. Bacteria and toxins  Infection type 1. Salmonella group 2. Proteus 3. Coli group 4. Shigella salmonella Symptoms appear in 24 to 48 hours of eating meal, mainly indicates Dr Hemanth S Naik, BMCRI
  • 5. Bacteria and toxins Toxic type  Due to performed toxins in prepared food such as canned and preserved food.  Eatables affected are meat, fish, egg.  Symptoms appear within 24 hours  More common in summer 1. Enterotoxin 2. Botulinum toxin Dr Hemanth S Naik, BMCRI
  • 6. Botulism  Botulismfrom Latin botulus = "sausage“, as bacterium often causes poisoning by growing in badly handled or prepared meat products.  Toxin destroyed at 80 degrees  Fatal dose is 0.01mg or even less  Blocks action of acetylcholine specific to autonomic nervous system Dr Hemanth S Naik, BMCRI
  • 7. Botulism  Incubation period –12-30 hours  Symptoms include vomiting, constipation, ocular paresis, muscular weakness, subnormal temperature  Mortality 25% to 100%  Treatment – polyvalent serum Dr Hemanth S Naik, BMCRI
  • 8. . Bon Vivant incident On July 2, 1971 the FDA released a public warningafter learning that a New York man had died and his wife had become seriously ill due to botulism after eating a can of the company’s Bon Vivant vichyssoise soup The FDA shut down Newark, New Jersey plant on July 7, 1971 Dr Hemanth S Naik, BMCRI
  • 9. Vegetable origin  Lathyrus sativus  Mushrooms  Argemona mexicana  Lolium temulentum Dr Hemanth S Naik, BMCRI
  • 10. Lathyrus sativus  Grows under extreme conditions of famine  B-(N)oxalyl aminoalanine BOAA, active principle  Causes neurolathyrism Dr Hemanth S Naik, BMCRI
  • 11. Neurolathyrism  Characterized by progressive spastic paraplegia with preservation of sphincters, ending in irreversible disability  Back pain>weakness of legs>difficulty in sitting>unable to walk>spastic gait>complete paralysis  Steeping the pulse in hot water and parboiling removes 90% of toxic amino acid Dr Hemanth S Naik, BMCRI
  • 12. . Dr Hemanth S Naik, BMCRI
  • 13. . During the Spain War of Independence against Napoleon, grasspea served as a famine food. This was the subject of one of Francisco de Goya's famous aquatint prints titled Gracias a la Almorta ("Thanks to the Grasspea"), depicting poor people surviving on a porridge made from grasspea flour, one of them lying on the floor, alreadyDr Hemanth S it. BMCRI crippled by Naik,
  • 14. Death cap  Unpleasant taste  Grows in woody places  Toxins are phalloidin, pahllon, 13 amanatin which are cyclopeptides Dr Hemanth S Naik, BMCRI
  • 15. Amanita muscaria  Have bitter taste  Changes color on cut section Dr Hemanth S Naik, BMCRI
  • 16. Signs and symptoms  Nausea  Vomiting  Diarrhoea  Convulsions  Collapse  Death Dr Hemanth S Naik, BMCRI
  • 17. Treatment  Antiphalloidien serum  Atropine sulphate  Silibin dihydrogen disaccinate sodium Dr Hemanth S Naik, BMCRI
  • 18. Argemona mexicana  Species of poppy found mainly in Mexico  Contains berberine, protopine, sanguinarine and dihydrosanguinarine  seeds resemble mustard and used as adulterant Dr Hemanth S Naik, BMCRI
  • 19. Signs and symptoms  Loss of appetite – diarrhoea  Edema of legs – anasarca  Vascular injuries  Telangiectasis Death due to severe damage to heart Dr Hemanth S Naik, BMCRI
  • 20. Lolium Temulentum  Weed grass grown in wheat field  Grains similar to wheat  Grains attacked by fungus containing Temuline  Headache, muscular weakness, coma Dr Hemanth S Naik, BMCRI
  • 21. Dr Hemanth S Naik, BMCRI
  • 22. Signs and symptoms  Source – Gambierdiscus toxicus  GI distress, hallucination and reverse of hot-cold sensation  Treatment – mannitol, amitriptylline Dr Hemanth S Naik, BMCRI
  • 23. Scombroid poisoning  Associated with sea food, stored improperly  Symptoms due to histidine converting into histamine above 60 degrees  Allergic symptoms Dr Hemanth S Naik, BMCRI
  • 24. Shellfish poisoning  GI disturbance  Neurotoxicity  Mutisim, memory loss, coma Dr Hemanth S Naik, BMCRI
  • 25. Dr Hemanth S Naik, BMCRI