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Research & Consulting
    Best Practices, LLC




                          1
Best Practices, LLC: Who We Are
At BPLLC, our strong, specialized industry background combines with broad
operational area experience to provide clients the ideal problem-solving perspective

                     Medical Affairs                    Competitive Intelligence
                    -Thought Leader Services              -Rapid Response Programs
                        -Medical Education
                      -Scientific Publications              -Structure & Alignment
             -Medical Information/Communication                -Strategic Insights
                 -Health Economics/Outcomes          -Maintaining legal & Ethical Standards
                   -Scientific/Medical Liaison         -Contracting Vendor/Outsourcing
               -Data Management & Biostatistics               -Resource & Budget
              -Clinical Operations & Trial Support        -Training & Data Collection


                    Sales Leadership                       Product Leadership
                  -Sales Force Effectiveness          -Brand Team Governance & Structure
                -Sales Manager Productivity               -Product Planning & Forecasting
                        -Sales Training                  -Product Marketing & Innovation
                    -Sales Force Structures                 -Product Staffing & Support
                    -Evolving Sales Models           -Brand Team Leadership & Management
                       -Sales Incentives                -Brand Team Performance Metrics
              -Market Entry & Managed Markets                 -Life Cycle Management



    Medical Device                      Pharmaceutical                         Biotech
                                                                                 2
Best Practices, LLC: Whom We Serve
Our clients include up-and-coming biotechs in addition to all of the top
50 pharma companies, including:




                                                         3
Best Practices, LLC: What We Offer
Our diversity of offerings allows business leaders to select precisely the tools
needed to succeed

                                                              Research and
                                                               Consulting
                                                               Benchmark
                                    Channels
                                                                Reports
  Pharmaceutical,                                             Best Practice
   Biotech, and                                                Database
  Medical Device
     Expertise                                               Best Practices
                                                              Excellence
                                    Services
                                                              Research and
                                                                Advisory

                                                                 4
A Closer Look: Research & Consulting Capabilities
                               Research and
                                Consulting       Best Practices, LLC's Research & Consulting Services
                  Channels   Benchmark Reports   is an innovative research, benchmarking and
Pharmaceutical,
 Biotech, and
                               Best Practice
                                Database
                                                 networking service for business executives.
Medical Device
   Expertise                   Best Practices
                                Excellence
                  Services
                               Research and
                                 Advisory
                                                 For nearly two decades, we have worked within the our
                                                 focus industries to promote top-line revenue growth,
                                                 cost reduction and creative problem-solving.




           We offer unparalleled opportunities to:

           • Collaborate with like-minded business leaders
             within the health sector

           • Target research into vital areas of specific
             industries

           • Participate in and access member-driven, RAS-
             directed primary research



                                                                                      5
Project Overview and Methodology
Best Practices, LLC helps companies accomplish the needs of its research by
benchmarking industry-leading pharma and biotech companies with the following
approach:



                  • Assess resources, processes or deliverables of a given functional area across the
                    industry to help client optimize its organization for efficiency and effectiveness
     Scope


                  • Capture the “What”: Internet survey gathers quantitative data on systems,
                    structure and resources to identify the most effective companies
                  • Understand the “Why”: We discover the practices behind those results through
   Approach         benchmarking interviews with key


               • Benchmarking Report: Detailed and prioritized best practices; focus on
                 implementation and actionable steps
               • Executive Presentation: Most important insights distilled and conveyed in on-
  Deliverables   site discussion of findings.



                                                                                 6
We Start Broad to Find Out How Others Solve Problems
By gathering insights from benchmark partners worldwide, we distill the very best of
the best methods to develop an “Integrated Best Practice System” for our clients




                                                                                Integrated Best Practice
                   Harvest Practices
  Study Relevant
    Companies




                                                                                        System
                                                    Clarify Key
                                       Prioritize



                                                     Findings
                                                                  Best of
                                                                   Best




                                                                            7
Our Service Crafts a Timeline Specific to Your Needs
Our research findings typically depict the 3-5 year future horizon that large
corporations require to implement complex programs with extended learning curves.

                                                     Year 1
                            Q2: Integrate & Absorb
     Q1: Study                                                Q3: Plan                          Q4: Budget
                                    Insights




                                                     Year 2
                  Q5-Q6: Pilot                                             Q7-Q8: Roll out




                                                     Year 3
                 Q9-Q11: Refine                                          Q12: Begin to Master




                                                 Year 4+
           Q13-Q14: Complete Mastery                              Q15 & Beyond: Field Leadership

                                                                                     8
Depth of Access Provides Highest-Quality Data
With deep access into management ranks of leading companies, we rapidly secure
valuable participation and insights from the most qualified leaders.


                  • Our “Secret Weapon”: Contacts information for
   Proprietary
                    more than 250,000 executive contacts among
  CRM Database
                    focus companies.



                  High-Impact     • We leverage technology to identify the
                   Targeting        most accomplished leaders to whom we
                                    should reach out


                                                         • Our compelling research process
                                          Effective        secures the interest and participation
                                         Recruiting        of these individuals



                                                                    Breadth of Results for
                                                                          Analysis


                                                                          9
Our Method and Design Provide Best Results
BPLLC’s survey instrument and expertise allows for rapid capture of accurate, detailed
metrics from the optimal benchmark class.


          Online Survey                                                                                     • Our internet technology simplifies participant
               Tool                                                                                           experience and generates faster results



                                                                                                           Expert
                                                                                                        Questionnaire                                                                                                            • We focus on design to generate
                                                                                                                                                                                                                                   the most accurate metrics
                                                                                                           Design



                                                                                                                                                                                                                                    Probing       • Rigorous, detailed analysis identifies
                                                                                                                                                                                                                                    Analysis        benchmark data and insights.


 Technological Capability: >500 Segment                                                               %Filled   Avg. #
                                                                                                      by date   open/recruiter                                      Perce nt of positions fille d by target date vs.
   More than 70% of respondents in the >500 segment rated their technological                                                                                           Number of ope n reqs per recruite r
   capability as high. Benchmark partners use both in-house and external systems
   to increase process automation. Furthermore, partners credit rob ust and
                                                                                                      75%
                                                                                                      80%
                                                                                                                6
                                                                                                                10                                                100%
                                                                                                                                                                                                        y = -0.0016x + 0.7965
                                                                                                                                                                                                                                                                Compelling
                                                                                                                                 Percent of positions filled by




   integrated technological systems for increased staffing process efficiency,                        84%       12                                                 90%
                                                                                                      90%       20                                                80%                                        R2 = 0.083
   especially through minimization and possible elimination of maintaining paper
                                                                                                      80%       20                                                70%
   records.
                                                                                                                                         target date




                                                                                                                                                                                                                                                           Presentation of Trends
                                                                                                      50%       20                                                60%
                                                                                                      80%       22                                                50%
                                                                                                      70%       22                                                40%
                         What is the level of technology integration/operational                      50%       22                                                30%
                                  capability in your staffing process?                                90%       23                                                20%
                                                                                                      75%       25                                                10%




                                                                                                                                                                                                                                                              and Takeaways
                                             Little or no capability                                  80%       25                                                 0%
                                                                                                      75%       30
                                                     3%                                                                                                                  0   20     40     60      80      100     120     140
                                                                                                      90%       30
                                                                       Some capability                                                                                             Average number of open reqs
                                                                                                      58%       35
                                                                            26%                       75%       35
                                                                                                      85%       35
                                                                                                      85%       40
                 High level of capability                                                             60%       40
                                                                                                      95%       50
                             71%                                                                      65%       50
                                                                                                      60%       75
                                                                                                      60%       120
                                                                                               ®
 Copyright  Best Practices®, LLC
                  Practices®                        20                            B S P A T E , LLC
                                                                                   E T R C IC S




                                                                                                                                                                                                                                                                      10
Additional Client Research Resources
We provide a comprehensive view of structures, staffing and best practices from
competitors and other world-class organizations. In addition to initial research from past
BPLLC work and secondary sources, projects may include:




           Benchmark Interviews follow a client-approved, customized guide through which
           trained researchers collect detailed insights and winning approaches from executives and
           managers at world-class companies




               Benchmark Surveys provide quantitative metrics that identify best-in-class
               companies and allow for performance gap analysis




           Site Visits allow for firsthand observations of practices at world-class companies,
           providing highly-detailed process information




                                                                              11
What Results Can BPLLC Achieve?
Our clients achieve marked results when implementing our recommendations and
research. Here are some examples of how we have helped:



                                              Client reorganized,            Group became
                            Identified         placing function               mainstay in
     Refined               misplaced CI         under Strategic                 strategic
                        function in Top-10       Planning with            discussions, with C-
    Structure           Pharma Company            senior-level                    Suite
                                                   oversight                representation



                                                                            Data bolstered
                                              Established staffing
    Improved             Functional areas
                         deemed too large
                                                 and efficiency
                                                                          defense of staffing
                                                                          levels for targeted
                                               metrics via peer
     Practices          by parent company
                                                benchmarking
                                                                           reduction areas,
                                                                            preserving jobs



                                              Obtained $10M in
                        Efforts to globally
    Increased              launch new
                                                  additional
                                                  resources,
                                                                          Client revenue grew
                                                                          61% in the following
                             products
    Resources             underfunded
                                              identified needed                two years
                                              marketing activities




                                                                     12
Why World-Class Companies Choose Us:
                                  Comprehensive Vision
                                         • “The Best Practices research team was able to conduct this important field
                                           research rapidly and with true global reach. The insights and findings will
                                           help us to focus and accelerate our performance management systems that
                                           are so important to sales excellence.“
                                           – Vice President, Sales & Marketing, AstraZeneca


Fast Turnaround

    • “I thought your material was very thorough and effective. It was very well
      done, especially given the short turnaround time.”
      – Director, Marketing Research, Bayer Pharmaceuticals


                                  Connectivity

                                         • “Best Practices provides access to a network of high-level benchmarking
                                           and performance improvement professionals, representing a virtual Who's
                                           Who of elite Fortune 500 companies.”
                                           – Senior Program Director, SCT


Actionable Insights
    • “The Best Practices team really helped me pioneer this market. The
      benchmarking research you performed for me delivered detailed, actionable
      insights. Your work was stellar!”
      -Manager, Business Development for GlaxoSmithKline Managed Markets
      Division
                                                                                                      13
Contact Us: Research & Consulting Services
  Executives at all of the top 50 global pharmaceutical companies
  and many other industry leaders turn to Best Practices, LLC for
      insightful, actionable solutions based on our analysis.


    Let our researchers uncover the next great insights for you!



                      Marty Daniel
                  Client Services Manager
                    Best Practices, LLC
                          919-767-9223
                    mdaniel@best-in-class.com
                     www.best-in-class.com
                                                    14

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Research and Consulting Offerings

  • 1. Research & Consulting Best Practices, LLC 1
  • 2. Best Practices, LLC: Who We Are At BPLLC, our strong, specialized industry background combines with broad operational area experience to provide clients the ideal problem-solving perspective Medical Affairs Competitive Intelligence -Thought Leader Services -Rapid Response Programs -Medical Education -Scientific Publications -Structure & Alignment -Medical Information/Communication -Strategic Insights -Health Economics/Outcomes -Maintaining legal & Ethical Standards -Scientific/Medical Liaison -Contracting Vendor/Outsourcing -Data Management & Biostatistics -Resource & Budget -Clinical Operations & Trial Support -Training & Data Collection Sales Leadership Product Leadership -Sales Force Effectiveness -Brand Team Governance & Structure -Sales Manager Productivity -Product Planning & Forecasting -Sales Training -Product Marketing & Innovation -Sales Force Structures -Product Staffing & Support -Evolving Sales Models -Brand Team Leadership & Management -Sales Incentives -Brand Team Performance Metrics -Market Entry & Managed Markets -Life Cycle Management Medical Device Pharmaceutical Biotech 2
  • 3. Best Practices, LLC: Whom We Serve Our clients include up-and-coming biotechs in addition to all of the top 50 pharma companies, including: 3
  • 4. Best Practices, LLC: What We Offer Our diversity of offerings allows business leaders to select precisely the tools needed to succeed Research and Consulting Benchmark Channels Reports Pharmaceutical, Best Practice Biotech, and Database Medical Device Expertise Best Practices Excellence Services Research and Advisory 4
  • 5. A Closer Look: Research & Consulting Capabilities Research and Consulting Best Practices, LLC's Research & Consulting Services Channels Benchmark Reports is an innovative research, benchmarking and Pharmaceutical, Biotech, and Best Practice Database networking service for business executives. Medical Device Expertise Best Practices Excellence Services Research and Advisory For nearly two decades, we have worked within the our focus industries to promote top-line revenue growth, cost reduction and creative problem-solving. We offer unparalleled opportunities to: • Collaborate with like-minded business leaders within the health sector • Target research into vital areas of specific industries • Participate in and access member-driven, RAS- directed primary research 5
  • 6. Project Overview and Methodology Best Practices, LLC helps companies accomplish the needs of its research by benchmarking industry-leading pharma and biotech companies with the following approach: • Assess resources, processes or deliverables of a given functional area across the industry to help client optimize its organization for efficiency and effectiveness Scope • Capture the “What”: Internet survey gathers quantitative data on systems, structure and resources to identify the most effective companies • Understand the “Why”: We discover the practices behind those results through Approach benchmarking interviews with key • Benchmarking Report: Detailed and prioritized best practices; focus on implementation and actionable steps • Executive Presentation: Most important insights distilled and conveyed in on- Deliverables site discussion of findings. 6
  • 7. We Start Broad to Find Out How Others Solve Problems By gathering insights from benchmark partners worldwide, we distill the very best of the best methods to develop an “Integrated Best Practice System” for our clients Integrated Best Practice Harvest Practices Study Relevant Companies System Clarify Key Prioritize Findings Best of Best 7
  • 8. Our Service Crafts a Timeline Specific to Your Needs Our research findings typically depict the 3-5 year future horizon that large corporations require to implement complex programs with extended learning curves. Year 1 Q2: Integrate & Absorb Q1: Study Q3: Plan Q4: Budget Insights Year 2 Q5-Q6: Pilot Q7-Q8: Roll out Year 3 Q9-Q11: Refine Q12: Begin to Master Year 4+ Q13-Q14: Complete Mastery Q15 & Beyond: Field Leadership 8
  • 9. Depth of Access Provides Highest-Quality Data With deep access into management ranks of leading companies, we rapidly secure valuable participation and insights from the most qualified leaders. • Our “Secret Weapon”: Contacts information for Proprietary more than 250,000 executive contacts among CRM Database focus companies. High-Impact • We leverage technology to identify the Targeting most accomplished leaders to whom we should reach out • Our compelling research process Effective secures the interest and participation Recruiting of these individuals Breadth of Results for Analysis 9
  • 10. Our Method and Design Provide Best Results BPLLC’s survey instrument and expertise allows for rapid capture of accurate, detailed metrics from the optimal benchmark class. Online Survey • Our internet technology simplifies participant Tool experience and generates faster results Expert Questionnaire • We focus on design to generate the most accurate metrics Design Probing • Rigorous, detailed analysis identifies Analysis benchmark data and insights. Technological Capability: >500 Segment %Filled Avg. # by date open/recruiter Perce nt of positions fille d by target date vs. More than 70% of respondents in the >500 segment rated their technological Number of ope n reqs per recruite r capability as high. Benchmark partners use both in-house and external systems to increase process automation. Furthermore, partners credit rob ust and 75% 80% 6 10 100% y = -0.0016x + 0.7965 Compelling Percent of positions filled by integrated technological systems for increased staffing process efficiency, 84% 12 90% 90% 20 80% R2 = 0.083 especially through minimization and possible elimination of maintaining paper 80% 20 70% records. target date Presentation of Trends 50% 20 60% 80% 22 50% 70% 22 40% What is the level of technology integration/operational 50% 22 30% capability in your staffing process? 90% 23 20% 75% 25 10% and Takeaways Little or no capability 80% 25 0% 75% 30 3% 0 20 40 60 80 100 120 140 90% 30 Some capability Average number of open reqs 58% 35 26% 75% 35 85% 35 85% 40 High level of capability 60% 40 95% 50 71% 65% 50 60% 75 60% 120 ® Copyright  Best Practices®, LLC Practices® 20 B S P A T E , LLC E T R C IC S 10
  • 11. Additional Client Research Resources We provide a comprehensive view of structures, staffing and best practices from competitors and other world-class organizations. In addition to initial research from past BPLLC work and secondary sources, projects may include: Benchmark Interviews follow a client-approved, customized guide through which trained researchers collect detailed insights and winning approaches from executives and managers at world-class companies Benchmark Surveys provide quantitative metrics that identify best-in-class companies and allow for performance gap analysis Site Visits allow for firsthand observations of practices at world-class companies, providing highly-detailed process information 11
  • 12. What Results Can BPLLC Achieve? Our clients achieve marked results when implementing our recommendations and research. Here are some examples of how we have helped: Client reorganized, Group became Identified placing function mainstay in Refined misplaced CI under Strategic strategic function in Top-10 Planning with discussions, with C- Structure Pharma Company senior-level Suite oversight representation Data bolstered Established staffing Improved Functional areas deemed too large and efficiency defense of staffing levels for targeted metrics via peer Practices by parent company benchmarking reduction areas, preserving jobs Obtained $10M in Efforts to globally Increased launch new additional resources, Client revenue grew 61% in the following products Resources underfunded identified needed two years marketing activities 12
  • 13. Why World-Class Companies Choose Us: Comprehensive Vision • “The Best Practices research team was able to conduct this important field research rapidly and with true global reach. The insights and findings will help us to focus and accelerate our performance management systems that are so important to sales excellence.“ – Vice President, Sales & Marketing, AstraZeneca Fast Turnaround • “I thought your material was very thorough and effective. It was very well done, especially given the short turnaround time.” – Director, Marketing Research, Bayer Pharmaceuticals Connectivity • “Best Practices provides access to a network of high-level benchmarking and performance improvement professionals, representing a virtual Who's Who of elite Fortune 500 companies.” – Senior Program Director, SCT Actionable Insights • “The Best Practices team really helped me pioneer this market. The benchmarking research you performed for me delivered detailed, actionable insights. Your work was stellar!” -Manager, Business Development for GlaxoSmithKline Managed Markets Division 13
  • 14. Contact Us: Research & Consulting Services Executives at all of the top 50 global pharmaceutical companies and many other industry leaders turn to Best Practices, LLC for insightful, actionable solutions based on our analysis. Let our researchers uncover the next great insights for you! Marty Daniel Client Services Manager Best Practices, LLC 919-767-9223 mdaniel@best-in-class.com www.best-in-class.com 14