Trends And Funding In Deep Tech
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Talk given in Dec 2019 - mixing content from our Deep Tech Trends + Funding Deep Tech Startups talk. Includes our new fund info ($277M raised!).
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Trends And Funding In Deep Tech
- 1. 776.65.8 576.65 776.65.8 576.65 776.65.8 576.65 776.65.8 576.65 776.65.8 576.65 776.65.8 576.65 776.65.8 576.65 776.65.8 576.65 776.65.8 576.65 776.65.8 576.65 776.65.8 576.65 776.65.8 576.65 1 Trends & Funding in Deep Tech www.sosv.com Benjamin Joffe Partner @benjaminjoffe
- 2. Agenda 1. SOSV Intro 2. Investment Landscape 3. Consumer 4. Enterprise 5. Frontier Tech 6. Health 7. Biology 8. Investing in Deep Tech
- 3. About SOSV Deep Tech & Hands-on Early Stage Deep Tech $277m Fund size 150 Startups/year
- 4. Our Programs Hands-on support Over 100 staff dedicated to support Electronics and wet labs Outstanding mentors, peers & alumni
- 5. HARDWARE LIFE SCIENCES FOOD ASIA CROSS-BORDER INTERNET & MOBILE HAX (Shenzhen, SF) IndieBio (SF) RebelBio (London) Food-X (NYC) Chinaccelerator (Shanghai) MOX (Taipei) Our Programs Hands-on support Robotics Cellular agriculture Functional food e-Commerce Industry 4.0 Gene therapy Food distribution Fintech Digital Health Consumer biology Food waste management Edutech Consumer devices Computational biology Adtech Neurotech SaaS $100k-$250k in cash & services Duration: 3-6 months Follow-on: Up to series B
- 7. Portfolio Highlights Unicorns & Rising Stars
- 8. Agenda 1. SOSV Intro 2. Investment Landscape 3. Consumer 4. Enterprise 5. Frontier Tech 6. Health 7. Biology 8. Investing in Deep Tech
- 9. Deep Tech by any Other Name⊠Deep Tech Science Tech Hard Tech Tough Tech Physical Tech DeepTech Trends2019 Emerging Tech Future Tech Frontier Tech Extreme Tech Dirty Tech
- 10. Defining Deep Tech Science & Engineering âAnything thatâs not an appâ
- 13. 1 in 5 Unicorns is in Deep Tech LIFE SCIENCES â 17 Henlius Novogene Sinocelltech WuXi NextCODE CureVac IronSource Nanopore Roivant 10X Genomics 23andMe Ginkgo BioWorks Grail Human Longevity Indigo Ag NantOmics Samumed Tempus Envision Prologium Northvolt Ovo Energy ReNew Power ChargePoint Microvast Rubicon Sila Nanotech View NEW ENERGY â 10 Aiways BAIC* Bordrin Byton Chehejia Enovate Hozon Leapmotor Nio* Singulato Skywell WeltMeister Yinglong Youxia Xpeng Motors Aurora Cruise** Faraday Future Nikola Motor Otto** Rivian TuSimple Zoox AV/EV â 23 Hellobike Mobike** Bolt Ola Electric Bird Rides Lime Uber ATG MOBILITY â 7 Ankon iCarbonX United Imaging Alphaeon Auris** Butterfly Network HeartFlow MindMaze Proteus Health SmileDirectClub HEALTH TECH â 10 DJI Geek+ Ninebot Ubtech Nuro Zipline Zume Carbon Desktop Metal Formlabs Magic Leap MindMaze ROBOTICS â 7 3D PRINTING â 3 AR/VR â 2 SPACE TECH â 4 OneWeb Rocket Lab SpaceX Virgin Galactic* US China RoW 14 35 46 Cambricon Horizon Robotics Graphcore OrCam Bitmain Canaan Ebang BitFury IC & SEMI â 4 CRYPTO MINING â 4 IOT â 2 Nest** Infinidat * IPO ** M&A 95 Deep Tech Unicorns Sources: Crunchbase, Hurun Report, SOSV Analysis Beyond Meat* Impossible Foods NEW FOOD â 2 DeepTech Trends2019 www.sosv.com â www.slideshare.com/sosv
- 14. EUROPE Oxford Sciences Innovation (UK) ÂŁ450m High-Tech GrĂŒnderfonds (Ger/EU) âŹ316.5m IQ Capital (UK) $300m Ahren Innovation Capital (UK) $250m Inventure (Nordics) âŹ110m USA btov (EU) âŹ100m Lux Capital $1.1b NordicNinja (Nordics & Baltics) âŹ100m Data Collective $725m Karma Ventures (EU) âŹ70m Eclipse Ventures $500m Elaia (EU) âŹ65m OS Fund $250m Adara Ventures (EU) âŹ65m The Engine $205m Future Positive Capital (EU) âŹ51m Future Ventures $200m Voima Ventures (Nordics & Baltics) âŹ50m Anzu Partners $150m Vito Ventures (EU) âŹ30m Bolt $80m Apex Ventures (EU) âŹ10m Root Ventures $76.7269m Runa Capital $70m OTHER Main Sequence Ventures (Australia) $240m GLOBAL Abies Ventures (Japan) $100m SOSV $250m Beyond Next Ventures (Japan) $50m Entrepreneurs First $115m Real Tech Fund (Japan) $18m Hardware Club $50m Pi Ventures (India) $31m Some Deep Tech VCs >$5b to invest DeepTech Trends2019Note: Chinese funds are mostly generalists.
- 15. Some Specialists DeepTech Trends2019 Many active generalists Some specialist funds
- 16. Notes: most are B2B * includes co-investors SoftBank Vision Fund DeepTech Trends2019 Company Type Sector Funding* GM Cruise B2B AV tech $2.25B View B2B Smart glass $1.8B Nuro HAAS Delivery AV $1B Zume HAAS Pizza robot $423M Plenty B2B AgTech $226M Light Consumer Cameras $186M Nauto B2B Driving Coach $174M Brain Corp B2B AV Tech $125M TOTAL $6.1B*
- 17. Agenda 1. SOSV Intro 2. Investment Landscape 3. Consumer 4. Enterprise 5. Frontier Tech 6. Health 7. Biology 8. Investing in Deep Tech
- 18. 3D Printing The hype is long gone Stratasys Val: $1.24b Consumer 3D Printers From $500 to $5,000 DeepTech Trends2019
- 19. 3D Printing B2B2C is real SmileDirectClub Tele-dentistry Val: $7b DeepTech Trends2019 Chanel Mascara
- 20. Smart Speakers 200m+ units A.I.-enabled IoT boom Amazon 60% Google 25% Apple 5% DeepTech Trends2019 Other 10% Plug Light Nest Ring Sonos Roomba Bose Garmin Lexus Voice at the center of the Smart Home
- 21. Xiaomization Amazonization Commoditization at breakneck speed DeepTech Trends2019 Amazon: Oven, Buds, Frames, Loop, Glow, Flex, Sidewalk, Samuel L. Jackson
- 22. Consumer Drones DJI Dominates The Market DeepTech Trends2019 DJI Consumer & B2B drones Raised $105m Skydio Self-flying drone Raised $70m DJI is estimaated to control over 70% of the market. Several competitors like 3DR and Parrot exited the consumer segment.
- 23. iRobot (USA) >25mln units Val: $1.85b P/E ratio: 22 Ecovacs (China) >15mln units Val: $2b P/E ratio: 28 Consumer Robotics Crawlers 1 Androids 0 DeepTech Trends2019
- 24. Jibo $72.7m Anki $182m Makeblock (China) STEM robots Raised $80m Other Consumer Robots Voice assistants roadkill companion robots STEM still growing DeepTech Trends2019 UBTech (China) STEM & toy robots Raised $940m
- 25. China's A.I. Push China is the world's largest experiment in A.I. education Chinaâs new âA-B-C-D' Artificial intelligence Blockchain Cloud computing Data technology DeepTech Trends2019 A smart headband to track focus in a school near Shanghai Source: WSJ, Aug 2019
- 26. VR (Consumer) Sandbox VR (HK) VR arcade Raised $71m Sony, HTC, Oculus⊠6M devices in 2019? Hits: Netflix? Chat? Adult? Black Box VR VR gym Raised $2.5m DeepTech Trends2019 Still slow despite 2nd generation devices Some B2B2C VR for arcades, gym
- 27. Varjo (High-res VR) Raised $45.9m VR (B2B) Virtual Reality Therapy Physio, phobias, pain + Outpatient tracking Real Estate Tours Matterport (cam + soft) Raised $114M DeepTech Trends2019 Training Maintenance, surgery, language, active shooter simulations Training, Touring, Therapy Applications make sense & multiply
- 28. AR: B2C new gen >$500 B2B spreads slowly Magic Leap ($2,295) Raised $2.6b Hololens ($3,500) Glass Enterprise Edition 2 Training, industry, health $999+ Focals by North Raised $199.6M $600+ DeepTech Trends2019
- 29. Holograms OOH ads & desktop solutions Not Star Wars quite yet Looking Glass Raised $13.8m (On market, $600+) Light Field Lab Raised $35m (Prototype) HYPERVSN by Kino-Mo (On market) DeepTech Trends2019
- 30. DeepTech Trends2019 Kegg Kegel fertility sensor Lilu Pumping bra RayBaby Radar breathing monitor Raised $1.4m BabyTech & FemTech Towards more science
- 31. Peloton $58/month, 0% APR Snoo Buy or rent Grover Monthly rentals for electronics Raised âŹ60M DeepTech Trends2019 Rent vs. Buy Keeps up-to-date & updated Nura Personalized sound with OTA updates Raised $21.9m
- 32. Mobility AV, EV, Sharing DeepTech Trends2019 $7.4B $9B $12.4B $13.5B $14.3B $19B $20.8B $29.9B $38.1B $56.2BE-hailing Semiconductors AV sensors and ADAS components Connectivity/ infotainment Electric vehicles and charging Batteries Telematics and intelligent traffic Back end/ cybersecurity HMI and voice recognition AV software and mapping Investment since 2010 Source: McKinsey Analysis, CapitalIQ, Pitchbook Need for new Technologies, Infrastructures, Operations Policies DeepTech Trends2019
- 33. Youibot Vehicle inspection robots New infrastructure needed to extend uptime and compete DeepTech Trends2019 PushMe Battery tech & network Raised $1.3m Gogoro e-Scooters & charging stations Raised $480m Charge Point #1 EV charging network Raised $532.2m Charging, maintenance, and more
- 34. 0 00 00 00 00 China USA Norway Germany France 31,00035,00046,000 209,000 769,000 Source: CarSalesBase, 2018 Electric Vehicles boom in China Top EV Brands in 2018 EV sales in 2018 DeepTech Trends2019 486 EV makers in China 9 unicorns $18B invested since 2011 0 00 00 00 00 Tesla BAIC BYD Zotye 64,000 105,000 150,000165,000 245,000 Renault Nissan
- 35. Agenda 1. SOSV Intro 2. Investment Landscape 3. Consumer 4. Enterprise 5. Frontier Tech 6. Health 7. Biology 8. Investing in Deep Tech
- 36. 04/ Enterprise & Industry Trends Labor crisis in numerous sectors Agriculture, Manufacturing, Construction, Mining are next Boom in Transportation, Logistics and Retail China innovates on all fronts DeepTech Trends2019
- 37. Amazon Kiva (acq) >200,000 units Last-mile delivery Pilots Prime Air Filed with FAA Blimp Mothership Fake! Balyo (IPO) Partnership Canvas (acq) Autonomous carts Automates everything. âDark warehousesâsoon? DeepTech Trends2019
- 38. Fear of Amazon 6 River Systems Acquired by Shopify for $450m Raised $46m Exotec High density warehousing solution Raised $21.2m Fetch Robotics Raised $94m Pushes competitors toward turn-key and flexible solutions DeepTech Trends2019
- 39. Construction Multi-trillion-dollar markets From design to demolition
- 40. Mechasys Floor plan projection Rebartek Automated rebar cage prefabrication COBOD âBuilding on demandâ, Raised $2.5m Smart tools & automation for custom construction
- 41. Operations Restoration Demolition Wastack Landfill operations Bird control, 3d mapping fire, methane leaks Craft Robotics Mortar-raking robot
- 42. Cleaning Avidbots Floor cleaning Raised $26.6m Plecobot High-rise windows ViaBot Pavement Somatic Toilets DeepTech Trends2019 Clean Robotics Trash-sorting robot
- 43. Zume Robotic pizzerias on wheels Raised $423m Spyce Robot cooks & restaurants Raised $25.9m Cafe X Robotic coffee vending machine Raised $14.5m DeepTech Trends2019 Robots Cooks
- 44. Vending Robots SOSV Investments Oasis BowlPresso Paper recycling stations Dry cleaning in a box Fresh salads DeepTech Trends2019
- 45. Unmanned Retail China leads with micro-retail CVS, gyms, karaoke, nail salons & more BingoBox Automated CVS Raised $94.7m DeepTech Trends2019 SuperMonkey Gyms in containers $53m series D M-Bar Karaoke cabins Competitors abound Oâ2Nails Nail art printers 16y of nail tech
- 46. Industry 2.5 million robots 0 40 80 120 160 China Japan US Korea Germany 273840 55 154 China Japan US Korea Germany 0 200 400 600 800 328 774 217 327 140 Robots Installed in 2018 (â000 units) Source : International Federation of Robotics DeepTech Trends2019 2x in 3 years 154 40 Robot Density in 2018 (per 10,000 workers) +422,000 in 2018 1/3 in China
- 47. Demand for flexible solutions Development speed Integration time Ease of use Safety DeepTech Trends2019 Elephant Robotics Collaborative robots with visual interface Veo Robotics Vision, 3D sensing & AI Raised $28m Youibot Mobile applications in industrial settings
- 48. Augmenting workers Japet Soft exoskeleton for back pain prevention Raised $1.7m Nuada Power glove for tireless grip ProGlove Wearable barcode scanner Raised $49.1m DeepTech Trends2019
- 49. SmarTex Fabric fault detection Zero downtime Zero waste "5 steps of machine epiphany" Reactive Preventive Predictive Optimized Health Optimized Performance Source: https://www.augury.com/ AiSight Machine sensors Unspun 3D-woven custom-fit jeans DeepTech Trends2019
- 50. Drones go B2B Dedrone Drone detection technology Raised $43.2m Zipline Long-range drones (100 miles) high-value deliveries Raised $233m For deliveries or surveying Longer range, heavier cargo Agriculture, Oil & Gas, Mining, Surveying, Defense, etc. Delair (France) Industry solutions Acquired Airware Raised $14.5m DeepTech Trends2019
- 51. Biocarbon Engineering Tree-planting drone 300 pods = 1ha in 18min Raised $2.5m Dropcopter Pollination drones DeepTech Trends2019 Drones Novel applications
- 52. Bloom Energy Solid oxide fuel cells⚠Val: $386m Raised $825.7m VoltStorage Vanadium redox flow Residential fuel cells & micro-grid Energy Vault Gravity storage Raised $110m Energy Storage & management DeepTech Trends2019
- 53. Geo Enginering Novo Nutrients Fish feed from CO2-capturing bacteria Carbon Capture Technologies Greenhouse Gas Removal (GGR) Biochar (charcoal from biomass) Cool Planet Energy Systems Biochar-based agricultural products Raised $235.7m Carbon Engineering CO2-capture & synthetic fuel tech Raised $107.4m DeepTech Trends2019
- 54. AgTech Soil sensors Automation for - irrigation - weeding - harvesting Post-harvest Food safety harvest Source: AgTech Landscape 2019 by Seana Day , BetterFoodVentures.com DeepTech Trends2019
- 55. Indoor Farming Plenty (vertical urban farm) â $266m Ikea Indoor growing cultivator - $60 DeepTech Trends2019 FarmShelf Raised $6.4m
- 56. Precision agriculture Forward Robotics Long-range VTOL drones Blue River Technology A.I.-based precision weeding Acq. by John Deere ($305m) Tensorfield A.I.-based precision weeding robots Sensors & robots for better outputs DeepTech Trends2019 Nordetect Portable NPK soil testing
- 57. Apix Automated beehive maintenance EIO Diagnostics Inflammation diagnostic Internet of ⊠Smart Shepherd Pedigree tracker Bees, cows, sheep & more DeepTech Trends2019
- 58. High-Tech Breeding Experiment with face recognition to track: âą behavior âą eating patterns âą overall health DeepTech Trends2019
- 59. China AgTech Breeding half the worldâs 1 billion pigs with A.I. Face recognition Chinaâs Tech Giants Into Breeding Netease, Alibaba, JD⊠Challenges (1) Siblings (2) Fast change DeepTech Trends2019 RFID Tattoo scan IR & motion Animal tracking goes high-tech (3) Facing camera (4) Dirt Geese have small faces and eyes on the side
- 60. Agenda 1. SOSV Intro 2. Investment Landscape 3. Consumer 4. Enterprise 5. Frontier Tech 6. Health 7. Biology 8. Investing in Deep Tech
- 61. Lilium (Germany) Raised $101.4m Ehang (China) Raised $52m Flying Cars Volocopter (Germany) Raised $89.7m Dubai, Singapore, Germany AeroMobil (Slovakia) Raised âŹ9m BoeingStartups & corporates race for safety, autonomy, launchpads, recharge and ⊠permits. Airbus targets Paris in 2024 Uber Air targets Melbourne in 2023 DeepTech Trends2019
- 62. Space Tech Rocket Lab Small sats launchers Raised $215m Viable: launch, sensing, telecom Not quite: mining, debris, tourism⊠< 5,000 satellites orbit the Earth today ~ 35 companies work on launchers SpaceX Starlink 60 in LEO (target: 12,000) Estimated cost: $10b OneWeb 6 in LEO (target: 2,000) Raised $3b DeepTech Trends2019
- 63. Hyperloops Hyperloop Transportation Technologies 10km pilot plant in Guizhou, China Raised $108m (unconfirmed) The Boring Company Raised $233m Virgin Hyperloop One Pune-Mumbai 120km loop by 2021? Raised $295m 25 projects 10+ test tracks Costs & safety concerns remain DeepTech Trends2019
- 64. 'Out There' Commonwealth Fusion Systems MIT startup Raised $115m Boom Supersonic Raised $141m Commercially viable within 10 years? Quantum Computers IBM, Google, etc. Up to 160-qubit D-Wave Raised $204.7m DeepTech Trends2019
- 65. SpaceX (+ Starlink) Tesla SolarCity (acq. by Tesla) The Boring Company Neuralink Future of Life Institute (non-profit) OpenAI (non-profit) Elon Musk Elon Musk projects target either established or new markets. Several leverage public funding and subsidies. $33.3b val. $46.7b cap. $2.6b $920m val. $158m funding Think Tank $1b funding DeepTech Trends2019
- 66. Neural Interfaces Tracking, Stimulating, Connecting Neuralink (Elon Musk) Brain-machine interfaces Raised $158m CTRL-Labs Neural monitoring Acquired by Facebook for $500m+ DeepTech Trends2019
- 67. Agenda 1. SOSV Intro 2. Investment Landscape 3. Consumer 4. Enterprise 5. Frontier Tech 6. Health 7. Biology 8. Investing in Deep Tech
- 68. 06/ Health Tech Trends Regulation Include Remote Monitoring Reimbursement Digital Diagnostic devices multiply Digital Therapeutics DeepTech Trends2019 Behavior changes remain challenging
- 69. Successful companies improve the following areas Access Cost Outcomes Now must-have for successful fundraising and go-to-market.
- 70. Bisu Urine test For health & fitness Bitome Nuclear spectroscopy for molecular analysis Criam Blood test Blood type & diseases Blood & Beyond Microfluidics, point-of-care solutions Elapta Various fluids Molecular testing BBB Blood test Glucose, ketones, cholesterol Raised $21.5m Biopsin Microbial detection F&B, water, pharma DeepTech Trends2019
- 71. Zennea Snoring Sleep Tech Track, Trigger, Treat DeepTech Trends2019 Moona âNest for your head' Kokoon EEG headphones Withings Sleep tracking mat Bands, watches Apple, Fitbit, etc. Eight Raised $30m Bravrr Bruxism (teeth clinching & grinding) TRACK TRIGGER TREAT
- 72. Sana Health Chronic pain relief Caura Lactate & glucose tracking Aire by FoodMarble Digestive health Digital Therapeutics Replacing pills and lab tests? DeepTech Trends2019
- 73. Lief Therapeutics ECG smart patch for stress management $99/month Flow Neuroscience Depression treatment FDA approved tDCS stimulation & virtual therapy app ÂŁ399 Mental Health HabitAware Hair pulling, nail biting, etc. Top 10 in TIME 2018 MSRP: $149 Feel by Sentio Emotions sensor for anxiety, depression, etc. Raised $6.3m (Clinical trials) DeepTech Trends2019 Digital Therapies machine learning and biofeedback
- 74. Labrador Systems Assistive robot for independent living Raised $2m MindMaze (Switzerland) VR treatment for neurorehabilitation Raised $110.6m Rehab & x-Diversity DeepTech Trends2019 Wandercraft Exoskeleton wheelchair for the disabled Raised $23.4m For independent living and supporting physical and mental diversity
- 75. An Important Challenge for Health is Behavior Understanding impact of food, sleep, environment⊠Avoiding mental triggers, building new habits. DeepTech Trends2019
- 76. Agenda 1. SOSV Intro 2. Investment Landscape 3. Consumer 4. Enterprise 5. Frontier Tech 6. Health 7. Biology 8. Investing in Deep Tech
- 78. Cost per raw megabase of DNA sequence Cost of DNA sequencing fell DeepTech Trends2019
- 79. Building Blocks 20,000 known genes scientists can look up 350,000 proteins âon-the-shelf' 250,000 antibodies ready to order Low-cost lab robots & outsourced lab work DeepTech Trends2019 DeepTech Trends2019
- 80. Gingko Bioworks Custom organisms Raised $719m OpenTrons Lab automation Raised $10m Picks & Shovels DeepTech Trends2019 Digi.Bio Programmable micro-fluidics platform StÀmm Bioreactor for continuous large-scale production
- 81. Impossible Foods raised $687.5m for plant-based meat
- 82. Land use per gram of protein in m2 0.01 0.01 0.02 0.04 0.04 0.05 0.08 0.1 0.13 1.02Beef/mutton Pork Fresh Produce Poultry Eggs Dairy Rice Maize Pulses Wheat Source: Clark & Tilman, 2017 Looking for Sustainable Proteins Animal Protein Issues Cost Taste Texture Culture medium (FBSâŠ) Acceptance Land Water Suffering Antibiotics Antibiotic resistance Alternative Protein Issues DeepTech Trends2019
- 84. Stem Cells Yeast Bacteria
- 85. Heme Soy Legume hemoglobin from GMO Yeast Fermentation
- 88. Insulin Production From Animal Liver to Fermentation
- 89. Food Plants Algae Fungi Cell-Ag Sustainable Functional Curative DeepTech Trends2019 Source: Purple Orange Ventures, 2019
- 90. 2nd Domestication of Plants & Animals From Macro-organisms To Micro-organisms Source: Rethinking Food and Agriculture 2020-2030 RethinkX Sector Disruption Report, September 2019 by Catherine Tubb & Tony Seba
- 91. Inspiration: Rethinking Food and Agriculture 2020-2030, RethinkX Sector Disruption Report, September 2019 by Catherine Tubb & Tony Seba The Twilight of the Cow
- 92. Perfect Day (milk whey & casein) â $61.5m
- 93. Memphis Meats Beef and chicken Raised $20.1m New Age Meats âHybrid' sausages Plant-based protein + Lab-grown pork fat Raised $3.5m Food Meat from: Plants Stem cells Integriculture (Japan) Cultured foie gras Raised $2.75m Beyond Meat Plant-based meat IPO, $7.6b market cap DeepTech Trends2019 DeepTech Trends2019
- 94. Good Catch Plant/algae-based tuna & more Raised $18.7m Wild Type Cultured seafood Raised $16m Finless Foods Fish from stem cells Raised $3.5m New Wave Foods Plant/algae based shrimp Raised funding from Tyson Food Seafood from: Plants Algaes Stem cells DeepTech Trends2019
- 95. Perfect Day Dairy (on market) Raised $201.5m Clara Foods Egg whites Raised $16.8m Food CellAg âSweets' DeepTech Trends2019
- 96. Perfect Day Dairy (on market) Raised $61.5m Clara Foods Egg whites Raised $16.8m Food Other Products NotCo Plant-based mayo Raised $30m Glyph by Endless West Molecular Whiskey Raised $12.7m New Culture Plant-based cheese with cultured casein Raised $3.5m DeepTech Trends2019
- 97. Food For Animals Because Animals Cultured meat and supplements for pets Ynsect (France) Insect-based feed for aquaculture and pet nutrition Raised $172.3m DeepTech Trends2019
- 98. Livin Farms (edible insects farm)
- 99. Prejudice against new food is not new⊠âCockroach of the oceanââDevilâs fruitâ
- 100. Just donât look at them up close ;)
- 101. Food Waste Avoiding & Upcycling Waste Cambridge Crops (edible) Food coating (MIT) Raised $4m After 10 days Hexafly Insect farming & upcycle of food waste into Aqua feed, Chitin & Plant Nutrition. Raised $4m DeepTech Trends2019 Uncoated Coated Wasteless Dynamic pricing RFID Raised $4.2m Electro-Active Technologies Upcycling food waste info hydrogen using microbes & electro-chemistry
- 102. Ag Biotech Soil health, Plant health Pollination BeeFlow Precision bee nutrition for enhanced pollination Raised $3.5m DeepTech Trends2019 Indigo Plant microbiome solutions for crop nutrition Raised $609m Biome Makers Designer microbes using DNA sequencing & A.I. Raised $6.4m
- 103. Human Microbiome âThe Second Brainâ 2 kg of bacterias 1,000+ species 3 million genes (150x humans)
- 104. Microbiome & Gut Health Kaleido BioSciences Microbiome solutions Raised $165.5m Eligio Biosciences Targeted bio-therapeutic Raised $22.2m DeepTech Trends2019 BiomeSense Microbiome testing & storage Raised $2m Sun Genomics Personalized probiotics Raised $3m Gut-brain connection Emerging therapies e.g. allergies, autism)
- 105. Bio- materials Bolt Threads Spider silk & more Raised $213m AlgiKnit Seaweed yarn Raised $2.2m MycoWorks Mushroom leather Raised series A Tinctorium Non-chemical indigo dye Modern meadow Biomaterials & ingredients Raised $53.5m ZOAâą Cultured Leather DeepTech Trends2019
- 106. Geltor Synthetic human collagen For eye cream, etc. Raised $23m Lingrove âWood without treesââ Moldable, CO2-negative composite of flax fiber & resins Bio- materials
- 107. Deep Tech For Health
- 108. Color Genomics Genome testing for clinical-grade hereditary cancer, hearth health, medication response genes ($250) Raised $112m 23andMe Genome research for ancestry, genealogy, and inherited traits. Raised $786m Personal Genetics From ancestry to clinical grade DeepTech Trends2019 Chronomics Epigenetic testing. Biological age, smoke exposure, metabolic state. Raised $1.4m
- 109. Biomarkers For pre-symptom diagnostic and predictive drug design sRNAlytics A.I.-based sequencing for small RNA markers Raised $2.5m Grail (Illumina spin-off) Liquid biopsy for early stage cancer testing Raised $1.6b Jungla (acquired for by Invitae for $65m) A.I.-based clinical interpretation tool of genetic variant. Raised $2.8m DeepTech Trends2019
- 110. New Pharma COMPANY FOCUS COST ADVANTAGE Convalesce Stem cell therapy for Parkinson's disease & more Low-cost material and fast-track designation. Gavilan Biodesign Resistance-resilient (â4Dâ) drug design Computational biology with âwetware-in-the-loopâ. Lupa Bio Anti-inflammatory therapeutics Leveraging existing data for fast-track FDA process. Recursion Pharmaceuticals Treatments discovery Combining automation & A.I. with experimental biology, Serenity Bioworks Immune-tolerant gene therapy platform Improves gene therapies by dampening immune reactions. Startups Challenge Traditional Pharma Economics DeepTech Trends2019 Easier due diligence Faster time-to-market Lower capital needs Lower downstream dilution
- 111. Cell & Gene Therapy Kytopen Non-viral delivery of molecules into hard-to- transfect immune cells Raised $3.6m Serenity Bioworks Immune-tolerant gene therapy platform DNA Lite Gastrointestinal gene therapy Raised $1.5m Getting past, modulating or harnessing the immune system
- 112. Other Biotech SyntheX Gene therapy enabler. Screening tech for protein- protein interaction, including cancer pathways. Raised $6.4m Diadem Biotherapeutics Regenerative biologics, offering easier manufacturing and longer shelf life. Gavilan Biodesign Resistance-resilient (â4Dâ) drug design using computational biology w/ âwetware-in-the-loopâ. The platform can search through 100,000 trillion molecular compound structures per day Targeting the âundruggableâ, and other technologies
- 113. Frontier Biotech Prellis Biologics 3D-printing of vascularized organoids Raised $10.6m Catalog DNA-based data storage Raised $9.3m Storing data in DNA Bio-printing organoids Neurons grown on vascular scaffolds DeepTech Trends2019
- 114. Other Exciting Domains Longevity Therapies Inflammation, Cells, Metabolism, Mitochondria Pre-symptom disease detection Live cell therapies e.g. precision cancer targeting Organoids from research to implants DeepTech Trends2019
- 115. Aubrey de Grey (56) Biomedical gerontologist CSO, SENS Research Foundation VP, AgeX Therapeutics, Inc Author, Ending Aging âPeople in Middle Age Now Have a Fair Chance.â
- 116. Agenda 1. SOSV Intro 2. Investment Landscape 3. Consumer 4. Enterprise 5. Frontier Tech 6. Health 7. Biology 8. Investing in Deep Tech
- 119. New Models Supporting Science Startups To go from Lab to Market i-Corps (~100 locations in US) 7-weeks coaching program Created by Steve Blank Focus on customer development Entrepreneur First (7 countries) âTalent investorâ 14 weeks program Team formation + idea validation Deeptech Founders (France) 6 months part-time program Focus on customer development SOSV (global) âHands-on VCâ with experts & labs 3+ months programs Product & business development Non-investing Investing
- 120. Minimum Fundable Milestone Not always product! Specific: - Customer? - Team Member? - Certification?
- 121. Questions Do you need a PhD in everything?
- 122. Questions Do you need a PhD in everything? How to avoid the next Theranos?
- 124. Founders Risk Give up early Low social skills Canât execute âArtistâ Silicon Valley Burn Rate Caught Up In âStartup Theatreâ Canât get along âMakerâ Addiction DeathHarassment 1 2 3 4 5 6 7 8 9 10 At early stage the biggest risk is Founders Risk
- 126. âRight Brainâ Intuitive âLeft Brainâ Rational HBDI Herrmann Brain Dominance Instrument
- 127. Spock Rational & logical Kirk âThe ïŹnal frontierâ Scotty Processes Bones People
- 128. Biases 1. Star Wars bias 2. Ugly Duckling bias 3. Make-up bias 4. Darwin bias
- 129. Biases 1. Star Wars bias 2. Ugly Duckling bias 3. Make-up bias 4. Darwin bias
- 130. Star Wars bias
- 131. Fabric Printer
- 133. Unspun Bespoke jeans
- 134. Boring & Viable Those robots target clear markets
- 135. Rebartek
- 136. Wow & Profit are often Orthogonal Lower tech, but much more viable
- 137. Biases 1. Star Wars bias 2. Ugly Duckling bias 3. Make-up bias 4. Darwin bias
- 138. Ugly Duckling But sometimes the value is already there
- 139. Nura
- 140. Nura
- 141. Nura
- 142. Nura Nura raised a $21m series A. Stevie Wonder bought 3 pairs
- 144. Biases 1. Star Wars bias 2. Ugly Duckling bias 3. Make-up bias 4. Darwin bias
- 146. Nura
- 149. Biases 1. Star Wars bias 2. Ugly Duckling bias 3. Make-up bias 4. Darwin bias
- 150. âThe year has not been productive in contributions of interest and valueâ Thomas Bell (1858) President, Linnean Societ
- 152. Holograms IceCream