Brief presentation of how protein is transported across the mitochondrial membraane and through nuclear pore complex

1. The Transport of Proteins into Mitochondria Rohit Bhardwaj B.E. 2 nd year Biotechnology Delhi Technological University, Shahbad Daulatpur, New Delhi, INDIA.

4. Mitochondrial Precursor Proteins Are Imported into the Matrix at Contact Sites That Join the Inner and Outer Membranes Proteins transiently spanning the inner and outer mitochondrial membranes during their translocation into the matrix

9. Protein import from the cytosol into the inner mitochondrial membrane or intermembrane space

10. The nuclear envelope

11. Nuclear Pores Perforate the Nuclear Envelope

12. Nuclear Import Receptors Bind Nuclear Localization Signals and Nucleoporins Possible paths for free diffusion through the nuclear pore complex.

13. Nuclear Import Receptors Bind Nuclear Localization Signals and Nucleoporins

15. The Ran GTPase Drives Directional Transport Through Nuclear Pore Complexes The compartmentalization of Ran-GDP and Ran-GTP.

16. A model for how GTP hydrolysis by Ran provides directionality for nuclear transport

17. A model for how the binding of Ran-GTP might cause nuclear import receptors to release their cargo