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THE HUMAN NUTRITION
RETHABILE CHABELI
• DISCUSS, IDENTIFY AND INTERPRET THE
PATHWAY OF FOOD THROUGH THE BODY AND
PROCESSES THROUGH WHICH FOOD IS BROKEN DOWN
AND USED BY THE BODY.
• MAKE INFERENCES FROM DIAGRAMS AND
GRAPHS.
• DRAW VARIOUS PARTS AND ORGANS OF THE
HUMAN DIGESTIVE TRACT.
• IDENTIFY AND DISCUSS THE HUMAN DIGESTIVE
TRACT BY EXPLAINING THE FUNCTIONS, LOCATION AND
AND STRUCTURE OF THE VARIOUS ORGANS OF THE
HUMAN DIGESTIVE TRACT.
• DISTINGUISH BETWEEN CHEMICAL AND
MECHANICAL DIGESTION.
• EXPLAIN THE ADAPTATION OF THE VILLI TO ITS
FUNCTION.
• DISCUSS THE DIFFERENT PROCESSES ASSOCIATED
WITH NUTRITION.
STRUCTURE OF HUMAN DIGESTIVE
TRACT
• Humans have a complete digestive tract
 begins with mouth & ends with anus.
• The major structures of human digestive
tract:
• mouth,
• pharynx,
• esophagus,
• stomach,
• small intestine,
• large intestine,
• rectum and
• anus.
THE ACCESSORY ORGANS OF
DIGESTION ARE THE
•Liver
•Salivary glands
•gall bladder
•pancreas
WHY IS DIGESTION IMPORTANT?
To convert large
(insoluble molecules)
of food  smaller
soluble molecules
absorbed into the
blood or lymph
capillaries &
used for various
metabolic processes.
DIGESTIVE PROCESS
•INGESTION
•DIGESTION – MECHANICAL
AND CHEMICAL
•ABSORPTION
•ASSIMILATION
•EXCRETION
PATHWAY OF FOOD AND
RELATED PROCESSES IN
THE BODY
MOUTH
•Ingestion:
•Teeth:
- Mechanical digestion
STRUCTURE OF A MOLAR
SALIVA
 Secreted by the salivary
glands (parotid gland,
sublingual gland & sub-
maxillary gland)
bolus.
• Saliva contains enzyme
(amylase)
• Chemical digestion.
TONGUE
• Mixes food with saliva & pushes food
between teeth.
• Makes swallowing easier.
ESOPHAGUS
•Bolus  forced down  esophagus
•NB!!! Peristalsis
•No absorption takes place
• epiglottis
EPIGLOTTIS
PROCESS OF PERISTALSIS
PERISTALSIS
STOMACH (ISISU)
• Food enters the stomach
• Remains 30 min  (peristalsis).
• Food move with circular movements through
stomach
• Mechanical digestion
• Gastric juices  gastrin
• Gastric juices consist of:
• 1.HCl
• 2.digestive enzymes
• 3.mucus
• 4.water.
•Gastric juices  chemical digestion 
chym.
• Some absorption occurs in stomach:
• water, glucose, salt and certain drugs and
alcohol
SMALL INTESTINE
• Chym enters duodenum (
• Mix with bile &
• pancreatic juices.
CHEMICAL DIGESTION
• Secretin  pancreatic juice
• Pancreatic juice contain:
• sodium bicarbonate
• digestive enzymes
• Bile
FUNCTIONS OF BILE
•Neutralizes acid
•Emulsifies fats
•absorption of fats.
•Reduce fluidity
•Antiseptic
•absorption of fat-soluble
vitamins.
•Chym moves through jejunum
•Mixes with intestinal juice (succus
entericus)
• Peptidase, lipase, lactase, maltase, sucrase
•Succus entericus
• Crypt of Lieberkuhn & glands
of Brunner
MECHANICAL DIGESTION
• The 2 muscle layer of the small intestine helps
with the process of peristalsis.
Cross section through the small intestine
FUNCTIONS OF THE LIVER - ISIBINDI
•Produces & secretes bile.
•Stores glucose glycogen & controlled
by hormone insulin.
•Convert excess carbohydrates into
(fatty acids + glycerol) = fats.
•Stores blood temporarily
•Manufactures plasma proteins
Forms heparin
•Detoxifies
• Liver breaks down surplus amino acids
through process of deamination:
• Change amino acid  ammonia.
• 2 x ammonia molecules combine with
1 molecule of CO2  urea & water.
• Urea conveyed to kidneys for
excretion.
• Deaminated amino acids converted into
glucose (glucose converted to glycogen
& stored in liver)
BLOOD SUPPLY OF THE LIVER
• Hepatic portal vein  digested food
from small intestine to liver
• Hepatic artery  transports O2 &
nutrients to the liver (enter the liver).
• Inside liver blood of these 2 blood vessels
mix
• Waste moves out of liver cells &
transported hepatic vein  inferior
vena cava.
BLOOD SUPPLY TO THE
LIVER CELLS
ABSORPTION FROM THE SMALL
INTESTINE
• Food mainly absorbed from small
intestine  where all final digestive
processes take place & end-products
of digestion is formed.
• The final products of digestion:
glucose, amino acids, fatty acids and
glycerol formed in small intestine.
ADAPTATIONS OF THE SMALL
INTESTINE FOR THE ABSORPTION
OF FOOD.
• The absorptive surface area is increased by:
• The great length of the small intestine (6-
7m)
• The circular folds of the mucosa lining of
the small intestine.
• The millions of villi lining the folds.
• The chym is pushed along very slowly
through the small intestine, allowing time
for absorption to take place.
STRUCTURE OF THE VILLUS
• Villus consist of several capillary arteries
supply villus with O2 &
• capillary veins  carry food away from the
villus.
• Lacteals (lymph vessels)  found in center of
each villus  used for the absorption of fats.
• Vessels surrounded by connective tissue & a
layer of columnar epithelial cells with goblet
cells
STRUCTURE OF THE VILLUS
THE PROCESS OF ABSORPTION IN
THE SMALL INTESTINE
•The columnar epithelial cells play
active part in absorption & able to
allow substances to enter villi
•Amino acids, glucose, mineral salts,
water & vitamins absorbed directly into
the blood.
FAT ABSORPTION FROM SMALL
INTESTINE
• Fatty acids (insoluble) combine with bile salts
• To form fatty acid-bile salt complex which is
(soluble) in water.
• This complex plus glycerol component of fat 
absorbed by columnar epithelial cells of villi.
• Inside villus  fatty acids freed from the bile
salts & recombine with glycerol to form tiny fat
globules.
FAT ABSORPTION FROM SMALL
INTESTINE
• Some of the fat globules are absorbed
directly into the blood capillaries.
• Most fat globules are absorbed by the
lacteals.
• The lacteals unite to form small lymph
vessels which enter main lymphatic system.
• Fat in lacteal now known as chyle, & it
reaches bloodstream in the end.
LARGE INTESTINE
•No digestion takes place in the
colon.
•Undigested food particles from
small intestine enter the caecum
through ileocaecal valve.
•In colon  water is absorbed 
chym becomes semi-solid.
LARGE INTESTINE
• Symbiotic bacteria present in colon act
upon food rests  decomposing them &
turning them into faeces.
• Bacteria synthesize vitamins Bgroups and K 
essential for blood clotting process.
• Peristalsis in colon  facilitated by mucus
produced by numerous mucous glands.
• Mucus assists the movement of feces &
protects the wall of the colon.
HUMAN COLON
RECTUM
•By the time feces reach the
rectum  consist of
approximately 70% water.
•Bacteria account for about
30% of dry mass of feces
•Remainder made up of food
residue (mainly cellulose).
FAECES STORED IN RECTUM
ANUS
•Defecation (excretion)  brought
about by
•contraction of the circular muscles
of rectum &
•relaxation of the muscles which
make up the anal sphincter.
REFERNCES
• Singh P, 2018. Human Digestive system. Available at:
https://www.slideshare.net/poojasingh676/plant-kingdom-112561675?next_slideshow=1
• Cena, S., 2009. Human digestive system. Available at:
https://www.slideshare.net/sjcena/human-digestive-system?qid=945724ff-61bc-468d-
8dd5-a20b0331e6f9&v=&b=&from_search=2
• Jose, A., S. 2017. Human digestive system: Grade 8. Available at:
https://www.slideshare.net/AaronJose1/the-human-digestive-system-
72847607?qid=28d94033-774a-4172-b4eb-b4f188fc1bf7&v=&b=&from_search=7
• Bhatia S., K. 2018. Physiology of human digestive system. Available at:
https://www.slideshare.net/sanjayqau47/physiology-of-human-digestive-
system?qid=38f8aa67-4bd3-441a-958e-8c09eae8da14&v=&b=&from_search=8
• Nori H, 2015. Digestive system structure and functions. Available at:
https://www.slideshare.net/khushbo0/human-digestive-system-49903659?qid=6cc6dcf7-
90ce-476f-8462-341796a9e12a&v=&b=&from_search=11
• Bhatti S,. S. 2018. Digestive system. Available at:
https://www.slideshare.net/ShaharyarShoukatShou/human-digestive-system-
94253896?qid=24f0b02f-6dc9-41c9-b124-
07c9727afcca&v=&b=&from_search=12

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GBSN - Biochemistry (Unit 1)
GBSN - Biochemistry (Unit 1)GBSN - Biochemistry (Unit 1)
GBSN - Biochemistry (Unit 1)
 

Unit 1 human nutrition

  • 2. • DISCUSS, IDENTIFY AND INTERPRET THE PATHWAY OF FOOD THROUGH THE BODY AND PROCESSES THROUGH WHICH FOOD IS BROKEN DOWN AND USED BY THE BODY. • MAKE INFERENCES FROM DIAGRAMS AND GRAPHS. • DRAW VARIOUS PARTS AND ORGANS OF THE HUMAN DIGESTIVE TRACT. • IDENTIFY AND DISCUSS THE HUMAN DIGESTIVE TRACT BY EXPLAINING THE FUNCTIONS, LOCATION AND AND STRUCTURE OF THE VARIOUS ORGANS OF THE HUMAN DIGESTIVE TRACT. • DISTINGUISH BETWEEN CHEMICAL AND MECHANICAL DIGESTION. • EXPLAIN THE ADAPTATION OF THE VILLI TO ITS FUNCTION. • DISCUSS THE DIFFERENT PROCESSES ASSOCIATED WITH NUTRITION.
  • 3. STRUCTURE OF HUMAN DIGESTIVE TRACT • Humans have a complete digestive tract  begins with mouth & ends with anus. • The major structures of human digestive tract: • mouth, • pharynx, • esophagus, • stomach, • small intestine, • large intestine, • rectum and • anus.
  • 4. THE ACCESSORY ORGANS OF DIGESTION ARE THE •Liver •Salivary glands •gall bladder •pancreas
  • 5.
  • 6. WHY IS DIGESTION IMPORTANT? To convert large (insoluble molecules) of food  smaller soluble molecules absorbed into the blood or lymph capillaries & used for various metabolic processes.
  • 7. DIGESTIVE PROCESS •INGESTION •DIGESTION – MECHANICAL AND CHEMICAL •ABSORPTION •ASSIMILATION •EXCRETION
  • 8. PATHWAY OF FOOD AND RELATED PROCESSES IN THE BODY
  • 10. STRUCTURE OF A MOLAR
  • 11. SALIVA  Secreted by the salivary glands (parotid gland, sublingual gland & sub- maxillary gland) bolus. • Saliva contains enzyme (amylase) • Chemical digestion.
  • 12. TONGUE • Mixes food with saliva & pushes food between teeth. • Makes swallowing easier.
  • 13. ESOPHAGUS •Bolus  forced down  esophagus •NB!!! Peristalsis •No absorption takes place • epiglottis
  • 17. STOMACH (ISISU) • Food enters the stomach • Remains 30 min  (peristalsis). • Food move with circular movements through stomach • Mechanical digestion
  • 18. • Gastric juices  gastrin • Gastric juices consist of: • 1.HCl • 2.digestive enzymes • 3.mucus • 4.water.
  • 19. •Gastric juices  chemical digestion  chym. • Some absorption occurs in stomach: • water, glucose, salt and certain drugs and alcohol
  • 20.
  • 21. SMALL INTESTINE • Chym enters duodenum ( • Mix with bile & • pancreatic juices.
  • 22. CHEMICAL DIGESTION • Secretin  pancreatic juice • Pancreatic juice contain: • sodium bicarbonate • digestive enzymes • Bile
  • 23.
  • 24. FUNCTIONS OF BILE •Neutralizes acid •Emulsifies fats •absorption of fats. •Reduce fluidity •Antiseptic •absorption of fat-soluble vitamins.
  • 25. •Chym moves through jejunum •Mixes with intestinal juice (succus entericus) • Peptidase, lipase, lactase, maltase, sucrase •Succus entericus • Crypt of Lieberkuhn & glands of Brunner
  • 26. MECHANICAL DIGESTION • The 2 muscle layer of the small intestine helps with the process of peristalsis. Cross section through the small intestine
  • 27. FUNCTIONS OF THE LIVER - ISIBINDI •Produces & secretes bile. •Stores glucose glycogen & controlled by hormone insulin. •Convert excess carbohydrates into (fatty acids + glycerol) = fats.
  • 28. •Stores blood temporarily •Manufactures plasma proteins Forms heparin •Detoxifies
  • 29. • Liver breaks down surplus amino acids through process of deamination: • Change amino acid  ammonia. • 2 x ammonia molecules combine with 1 molecule of CO2  urea & water. • Urea conveyed to kidneys for excretion. • Deaminated amino acids converted into glucose (glucose converted to glycogen & stored in liver)
  • 30. BLOOD SUPPLY OF THE LIVER • Hepatic portal vein  digested food from small intestine to liver • Hepatic artery  transports O2 & nutrients to the liver (enter the liver). • Inside liver blood of these 2 blood vessels mix • Waste moves out of liver cells & transported hepatic vein  inferior vena cava.
  • 31. BLOOD SUPPLY TO THE LIVER CELLS
  • 32. ABSORPTION FROM THE SMALL INTESTINE • Food mainly absorbed from small intestine  where all final digestive processes take place & end-products of digestion is formed. • The final products of digestion: glucose, amino acids, fatty acids and glycerol formed in small intestine.
  • 33. ADAPTATIONS OF THE SMALL INTESTINE FOR THE ABSORPTION OF FOOD. • The absorptive surface area is increased by: • The great length of the small intestine (6- 7m) • The circular folds of the mucosa lining of the small intestine. • The millions of villi lining the folds. • The chym is pushed along very slowly through the small intestine, allowing time for absorption to take place.
  • 34.
  • 35. STRUCTURE OF THE VILLUS • Villus consist of several capillary arteries supply villus with O2 & • capillary veins  carry food away from the villus. • Lacteals (lymph vessels)  found in center of each villus  used for the absorption of fats. • Vessels surrounded by connective tissue & a layer of columnar epithelial cells with goblet cells
  • 37. THE PROCESS OF ABSORPTION IN THE SMALL INTESTINE •The columnar epithelial cells play active part in absorption & able to allow substances to enter villi •Amino acids, glucose, mineral salts, water & vitamins absorbed directly into the blood.
  • 38. FAT ABSORPTION FROM SMALL INTESTINE • Fatty acids (insoluble) combine with bile salts • To form fatty acid-bile salt complex which is (soluble) in water. • This complex plus glycerol component of fat  absorbed by columnar epithelial cells of villi. • Inside villus  fatty acids freed from the bile salts & recombine with glycerol to form tiny fat globules.
  • 39. FAT ABSORPTION FROM SMALL INTESTINE • Some of the fat globules are absorbed directly into the blood capillaries. • Most fat globules are absorbed by the lacteals. • The lacteals unite to form small lymph vessels which enter main lymphatic system. • Fat in lacteal now known as chyle, & it reaches bloodstream in the end.
  • 40. LARGE INTESTINE •No digestion takes place in the colon. •Undigested food particles from small intestine enter the caecum through ileocaecal valve. •In colon  water is absorbed  chym becomes semi-solid.
  • 41. LARGE INTESTINE • Symbiotic bacteria present in colon act upon food rests  decomposing them & turning them into faeces. • Bacteria synthesize vitamins Bgroups and K  essential for blood clotting process. • Peristalsis in colon  facilitated by mucus produced by numerous mucous glands. • Mucus assists the movement of feces & protects the wall of the colon.
  • 43. RECTUM •By the time feces reach the rectum  consist of approximately 70% water. •Bacteria account for about 30% of dry mass of feces •Remainder made up of food residue (mainly cellulose).
  • 45. ANUS •Defecation (excretion)  brought about by •contraction of the circular muscles of rectum & •relaxation of the muscles which make up the anal sphincter.
  • 46. REFERNCES • Singh P, 2018. Human Digestive system. Available at: https://www.slideshare.net/poojasingh676/plant-kingdom-112561675?next_slideshow=1 • Cena, S., 2009. Human digestive system. Available at: https://www.slideshare.net/sjcena/human-digestive-system?qid=945724ff-61bc-468d- 8dd5-a20b0331e6f9&v=&b=&from_search=2 • Jose, A., S. 2017. Human digestive system: Grade 8. Available at: https://www.slideshare.net/AaronJose1/the-human-digestive-system- 72847607?qid=28d94033-774a-4172-b4eb-b4f188fc1bf7&v=&b=&from_search=7 • Bhatia S., K. 2018. Physiology of human digestive system. Available at: https://www.slideshare.net/sanjayqau47/physiology-of-human-digestive- system?qid=38f8aa67-4bd3-441a-958e-8c09eae8da14&v=&b=&from_search=8 • Nori H, 2015. Digestive system structure and functions. Available at: https://www.slideshare.net/khushbo0/human-digestive-system-49903659?qid=6cc6dcf7- 90ce-476f-8462-341796a9e12a&v=&b=&from_search=11 • Bhatti S,. S. 2018. Digestive system. Available at: https://www.slideshare.net/ShaharyarShoukatShou/human-digestive-system- 94253896?qid=24f0b02f-6dc9-41c9-b124- 07c9727afcca&v=&b=&from_search=12