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UNIVERSITY OF
MAURITIUS
Bachelor of Pharmacy Year 4
Pharmacognosy 4
Monographs of 5 Plants
Presented by: Naraino Majie Nabiilah-1216824
Joorawon Svenia-1217636
Date of Submission: 14th
September 2015
Monographs on: Page
1. Allium sativum 1
2. Apium graveolens 3
3. Citrus limon 5
4. Thymus vulgaris 7
5. Zingiber officinale 9
ALLIUM SATIVUM
1
Allium sativum
MAIN COMPONENTS
• Essential Oil (disulfide
diallyl, allicme)
• Carbohydrates
• Selenium
• Vitamins A, B, C and E
• Sulfur Compounds
MAIN EFFECTS
• Antibiotic
• Expectorant
• Active sweating
• Hypotensor
• Reduces blood clots
• Hypoglycemic
• Anthelmintic
GARLIC is the medicinal plant par
excellence. It is safe for home use
and proves effective to treat multiple
of health problems; it fights against
nose, throat and bronchi infections,
reduced cholesterol levels and
soothes circulatory disorders, such
as hypertension. Hypoglycemic,
garlic is a valuable supplement food
for diabetics. (Ayaz et al, 2007)
Garlic, very appreciated in the kitchen,
is grown for commercial purposes
TAXONOMY
Class: Equisetopsida
Subclass: Magnoliidae
Superorder: Lilianae
Order: Asparagales
Family: Amaryllidaceae
Genus: Allium
Scientific name: Allium sativum L.
Common name: garlic (English);
ajo (Spanish); ail (French); arishtha,
lashuna (Sanskrit); lasan (Hindu
and Gujarat); vellaipundu (Tamil).
Conservation status: Not
considered to be threatened.
Habitat: Rocky valleys, riverbeds,
streambeds and gullies.
Key Uses: Food and drink,
medicine, pest control.
Known hazards: Adverse effects
including a burning sensation in the
mouth and intestine, sickness, and
odour from the breath and the body.
Skin reactions have also been
reported. Garlic may interfere with
some prescribed medicines.
(Anon-2014, Ayaz et al-2007,
Anon-2010)
CURRENT RESEARCH
• A complex solution: The therapeutic effects of
garlic have been mentioned in more than thousand
scientific articles. Garlic lowers lipid levels and
cholesterol in the blood; it prevents the formation
blood clots, reduces blood pressure and also reduces
the blood sugar and exerts antibiotic action.
(Jangam et al, 2014)
• Mechanism of action: Chemical analysis in the
1800s attributed garlic's activity to the sulfur
containing garlic oil. In the mid 1900s an American
chemist named the strong smelling liquid "allicin".
The sulfur compound alliin (S-allyl-l-cysteine
sulfoxide) produces allicin (diallyl thiosulfinate) via
the enzyme allinase when the bulb is crushed or
ground. Other sulfur compounds, peptides, steroids,
terpenoids, flavonoids, and phenols have increasingly
been identified as possible active ingredients as
allicin is metabolized. The exact mechanism of
action underlying garlic's effects remains unknown
and may vary according to the preparation and the
therapeutic effect. (Anon, 2011)
TRADITIONAL & CURRENT USES
A traditional remedy: Before the invention of
antibiotics, garlic was used to treat all kinds of
diseases, from tuberculosis to typhoid fever. It was
also used for dressing wounds during WWI.
Bronchial Diseases: Garlic is great in case of
bronchial infections and treats colds as well as ear
infections.
The digestive tract: Garlic treats diseases of the
digestive system. It rids of the intestinal parasites.
The circulatory system: Garlic prevents circulatory
disorders and prevents their developments
by thinning the blood. It also decreases cholesterol
level.
Other uses: Garlic is used against infections; it
enhances the action of chemical antibiotics and
avoids side effects. It also reduces blood glucose, as
well as helps patients suffering from diabetes
mellitus.
PART USED
Bulbs
Cloves
Fresh
Plant
PREPARATION AND
USAGE
These parts
have been
used since
centuries in
medicine and
cooking for
its tonic
properties.
Garlic Syrup against
cough; take 1 spoon
every 3 hours
Minced cloves to
decrease cholesterol
and strengthen
immune system
These beads
contain garlic oil.
This increases the
resistance of the
body to infection.
ALLIUM SATIVUM
2
REFERENCES
Web links
ANON, 2010. Garlic (Allium sativum). Sigma-Aldrich [online]. Available from:
http://www.sigmaaldrich.com/life-science/nutrition-research/learning-center/plant-profiler/allium-
sativum.html [Accessed September 2015].
ANON, 2011. Garlic. Mr Ginseng [online]. Available from: http://en.mr-ginseng.com/garlic/
[Accessed September 2015].
ANON, 2014. Garlic (Allium Sativum L.). MedicineNet.com [online].Available from:
http://www.medicinenet.com/garlic_allium_sativum_l-oral/article.htm [Accessed September 2015].
ANON, 2015. Allium sativum (garlic). Kew Royal Botanic Gardens [online]. Available from:
http://www.kew.org/science-conservation/plants-fungi/allium-sativum-garlic [Accessed September
2015].
Journals
AYAZ, E. and ALPSOY, H.C., 2007. Garlic (Allium sativum) and traditional medicine. PubMed.gov;
31(2), 145-149. http://www.ncbi.nlm.nih.gov/pubmed/17594659
JANGAM, G.B. and BADOLE, S.L., 2014. Garlic (Allium sativum): Role in metabolic disorder.
Polyphenols in human health and disease; 1(46), 611-614.
http://www.sciencedirect.com/science/article/pii/B9780123984562000463
SULERIA, H.A.R., et al., 2015. Garlic (Allium sativum) : diet based therapy of 21st
century – a review.
Asian Pacific Journal of tropical disease; 5(4), 271-278.
http://www.sciencedirect.com/science/article/pii/S2222180814607829
SUNG, S., et al., 2014. Effects of Allium sativum essence oil as antimicrobial agent for food
packaging plastic film. Innovative Food Science & Emerging Technologies; 26, 406-414.
http://www.sciencedirect.com/science/article/pii/S1466856414000800
APIUM GRAVEOLENS
3
Apium graveolens var. graveolens
Celery is a plant used in both
medicine and cooking.
TAXONOMY
MAIN COMPONENTS
•Essential Oil (1.5 to 3%)
•Coumarins
•Furanocoumarins
(bergapten)
•Flavonoids (apune)
MAIN EFFECTS
•Antirheumatic
•Antispasmodic
•Diuretics
•Hypotensive
•Antiseptic
•Anti-
inflammatory
Kingdom: Plantae
(unranked): Angiosperms
Order: Apiales
Family: Apiaceae
Genus: Apium
Species: A. graveolens
MOST COMMONLY USED as a
vegetable than as medicaments, the
branches and seeds of celery treat
disorders such as rheumatism or
arthritis, celery helps cleanse the
body by removing toxins. Its seeds
effectively eliminate intestinal gas
and they relieve bloating related
abdominal pain. (Tobyn et al, 2011)
Scientific name: Apium graveolens L.
Common name: celery (English); apio
(Spanish); céleri (French); shalari
(Hindu and Gujarat); sedano (Italian).
Conservation status: Not considered to
be threatened except in Sweden.
Habitat: Marshy areas, terrestrial,
fresh water.
Key Uses: Vegetable, medicine,
dietary herb (China).
Known hazards: Adverse effects
include skin inflammation and
sensitivity to the sun. Unsafe for
pregnant women, people with bleeding
disorder, kidney problems and low BP.
(Anon- 2005, 2014, 2015)
CURRENT RESEARCH
• A complex solution: The essential oil
provides a calming effect on the nervous
system. Seed extracts may lower blood lipid
levels. Chinese Studies indicate that the oil is
effective against hypertension. Celery is a rich
source of phenolic phytonutrients that have
antioxidant and anti-inflammatory properties.
(Fuchs et al, 2012)
• Mechanism of action: Celery contains
phenols and furocoumarins (psoralens). Celery
seed oil contains the natural phthalide
sedanolide which showed protective effects
against hydrogen peroxide H2O2 and tert-butyl
hydroperoxide (tBOOH)-induced toxicity in
HepG2 and CaCo-2 cells. Celery tuber also
contains methoxsalen (8-methoxypsoralen)
and 5-methoxypsoralen and the allergen
profilin (Api g 1), which shows high homology
to birch pollen profilin. (Madhavi et al, 2013)
TRADITIONAL AND CURRENT USES
• An antique use: The use celery is cultivated
for at least 3000 years, particularly in Egypt. In
the fifth century BC, the Chinese already knew
about this plant. During history, celery has
always been consumed as food and at various
times, the whole plant and seeds were used for
medicinal purpose.
• The purifying properties: Today, the seeds
are used to treat gout and certain rheumatism.
They get the kidneys rid of their waste and
reduce the acidity of organ. Seeds treat arthritis
by detoxifying the body and improving blood
flow to the muscles and joints.
• A diuretic agent: Celery seeds have a mild
diuretic action and great antiseptic effect. They
are effective against cystitis since they
disinfect bladder.
PART USED
PREPARATION AND
USAGE
Leaves
All parts have
high nutritive
values but the
seeds are mostly
used in medicine.
Detoxifying drink; take one
cup of celery juice and
carrot juice once per day.
Seed infusion to treat gout
and arthritis; take one cup
with 1.5g of seed every day.
Powdered seeds to treat
arthritis; take one teaspoon
each day.
APIUM GRAVEOLENS
4
REFERENCES
Web links
ANON, 2005. Celery. WebMD [online]. Available from: http://www.webmd.com/vitamins-
supplements/ingredientmono-882-celery.aspx?activeingredientid=882&activeingredientname=celery
[Accessed September 2015].
ANON, 2015. Apium graveolens. Red List of Threatened Species [online]. Available from:
http://www.iucnredlist.org/details/164203/0 [Accessed September 2015].
ANON, 2015. Celery (Apium graveolens). Sigma-Aldrich [online]. Available from:
http://www.sigmaaldrich.com/life-science/nutrition-research/learning-center/plant-profiler/apium-
graveolens.html [Accessed September 2015].
EHRLICH, S.D., 2015. Celery seed. Milton S. Hershey Medicinal Center [online]. Available from:
http://pennstatehershey.adam.com/content.aspx?productId=107&pid=33&gid=000231 [Accessed
September 2015].
MURRAY, M.T., 2014. Celery and Celery seed extract are powerful, Proven healers.
DoctorMurray.com [online]. Available from: http://doctormurray.com/celery-and-celery-seed-extract-
are-powerful-proven-healers/ [Accessed September 2015].
Journals
FUCHS, M., et al., 2012. Development and validation of a novel real-time PCR method for the
detection of celery (Apium graveolens) in food. Food Chemistry; 130(1), 189-195.
http://www.sciencedirect.com/science/article/pii/S0308814611009526
MADHAVI, D, et al., 2013. A pilot study to evaluate the antihypertensive effect of a celery extract in
mild to moderate hypertensive patients. Natural Medicine Journal; 5(4).
http://naturalmedicinejournal.com/journal/2013-04/pilot-study-evaluate-antihypertensive-effect-
celery-extract-mild-moderate
MODARESI, M., et al., 2012. The effects of celery (Apium graveolens) extract on the reproductive
hormones in male mice. APCBEE Procedia; 4(2012), 99-104.
http://www.sciencedirect.com/science/article/pii/S221267081200187X
TOBYN, G, DENHAM, A. and WHITELEGG, M., 2011. Apium graveolens, wild celery. Medical
Herbs; 9, 79-89. http://www.sciencedirect.com/science/article/pii/B9780443103445000148
CITRUS LIMON
5
Citrus limon
MAIN COMPONENTS
• Essential Oil (2 – 5% in
fruit peel), sesquiterpenes,
terpenoids, aldehydes, esters
• Coumarins
• Flavonoids
• Vitamins
MAIN EFFECTS
• Antibacterial
• Antioxidant
• Anti-rheumatic
• Antiseptic
• Reduces fever
LEMON is a major natural remedy.
Common food with numerous
medicinal virtues, it is rich in
vitamin C and favours resistance
against infections which helps to
treat influenza and colds. It is
consumed in preventive way in case
of gastritis, circulatory problems and
atherosclerosis. (Anon, 2006)
Lemon treats scurvy (lack of
vitamin C).
TAXONOMY
Class: Magnoliophyta
Subclass: Dilleniidae
Superorder: Violanae
Order: Sapindales
Family: Rutaceae
Genus: Citrus
Scientific name: Citrus limon L.
Common name: lemon (English);
citron (French); limone (Italian);
limon (Creole); līmūn (Arabic);
nimbū (Sanskrit).
Conservation status: Least concern.
Habitat: Mediterranean region and
subtropical parts of the world.
Key Uses: Food and drink,
medicine, cosmetics.
Known hazards: Sore throat,
nausea, it may taste bitter after a
while.
(Anon- 2006, 2011,2012)
CURRENT RESEARCH
• A complex solution: Its most prominent
component, limonene, is likely the key to its
potency, found in many citrus oils but none so
strongly as lemon. Its cancer-fighting antioxidant
power is impressive, as well. (G. M. Et al, 2010)
• Mechanism of action: Its mode of action is not
clear. It acts in one or more different way to
exert its pharmacologic effect. (Bailey, 1976)
TRADITIONAL & CURRENT USES
Famous medication: Spanish folk medicine
attributes so much therapeutic values to lemon
that entire books have been devoted to it.
Established properties: Once digested, lemon
has an antacid effect which makes it effective in
case of rheumatoid arthritis which favours
acidity. The essential oil is antiseptic and
antibacterial. The flavonoids present strengthen
the inner wall of blood vessels and favour the
disappearance of varicose veins and reduction of
bruises.
Preventive action: Lemon is a distinguished
preventive remedy. Its antiseptic and detoxifying
properties make it an important ally for persons
prone to atherosclerosis, fever and infectious
diseases of the stomach, liver and intestine. Its
action on the wall of blood vessels helps to
prevent circulatory problems and bleeding gums.
It is also an excellent and effective tonic against
certain chronic diseases.
Stimulate veins’ walls: The fruit and white peel
prevent atherosclerosis and weakness of
capillaries.
Juice: Lemon juice fights colds, flu and
infections. It stimulates liver detoxification and
improves appetite. It is a tonic of the liver and
the pancreas and it fights against ulcers and
rheumatoid arthritis. As gargle, it treats sore
throat, gum disease and mouth ulcer. For
external use, it is applied on acne, athlete’s foot,
bites, sunburn and warts.
(Lopes et al-2011, Freitas et al-2014, Nakajima
et al-2014)
PART USED
Fruit and peel improve
circulation and strengthen
resistance against infections.
White peel and zest contain
essential oil and most
flavonoids.
PREPARATION AND USAGE
Lemon
contains
twice as
much as
vitamin
C as
orange.
Lemon essential
Oil.
Dilute 5 drops
in 1 teaspoon of
neutral oil and
apply on mouth
ulcers.
Remedy against colds; mix
20ml of lemon juice with
50ml of hot water and add 1
crushed clove of garlic
together with 1 pinch of
cinnamon. Drink the
mixture 3 times per day.
Lemon juice for
throat irritation.
Mix 20ml of
lemon juice
with 20ml of
hot water and
use as gargle.
CITRUS LIMON
6
REFERENCES
Web links
ANON, 2006. Citrus limon. Learn 2 grow [online]. Available from:
http://www.learn2grow.com/plants/citrus-limon/ [Accessed September 2015].
ANON, 2011. Citrus limon L. Taxonomy for plants [online]. Available from: http://www.ars-
grin.gov/cgi-bin/npgs/html/taxon.pl?10732 [Accessed September 2015].
ANON, 2012. Citrus limon – L. Plants for a future [online]. Available from:
http://www.pfaf.org/user/Plant.aspx?LatinName=Citrus+limon [Accessed September 2015].
BAILEY, et al., 1976. Lemon. Encyclopedia of Life [online]. Available from:
http://eol.org/pages/582200/overview [Accessed September 2015].
KASRAOUI, F., 2006. Le citronnier. Kasroui.com Le site officiel [online]. Available from:
http://www.kasraoui.com/Secteur-Agricole/Agrumes-Citronnier.html [Accessed 10 September
2015].
Journals
GONZALEZ-MOLINA, E. et al., 2010. Natural bioactive compounds of Citrus limon for food and
health. Journal of Pharmaceutical and biomedicinal analysis. 51(2), 327-345.
LOPES CAMPÊLO, L.M. et al., 2011. Antioxidant and Antinociceptive effects of Citrus limon
essential oil in mice. Journal of Biomedicine and Biotechnology. 2011(2011), 1-8.
Freitas, E. S., Viana, M. D. M., Silva-Neto, G. J., Oliveira, L. M. S., Duzzioni, M., Castro, O. W.,
Ferro, J. M. S., Barreto, E., Campesatto, E. A. and Alexandre-Moreira, M. S. (2014) ‘026 —
(FRE0127) Motor performance evaluation of mice treated with essential oil’, Epilepsy & Behavior,
38, pp. 192–193. doi: 10.1016/j.yebeh.2014.08.059.
Nakajima, V. M., Macedo, G. A. and Macedo, J. A. (1205) ‘Citrus bioactive phenolics: Role in the
obesity treatment’, LWT - Food Science and Technology, 59(2), pp. 1205–1212. doi:
10.1016/j.lwt.2014.02.060.
THYMUS VULGARIS
7
Thymus vulgaris
MAIN COMPONENTS
• Essential Oil (thymol,
carvacrol, linalol)
• Flavonoids
• Phenolics
MAIN EFFECTS
• Antiseptics
• Tonic
• Muscle relaxant
• Expectorant
• Vermifuge
• Antioxidant
Thyme is characteristic to the
Mediterranean flora; it is also known as
"farigoule" in southern France. Known for
its aromatic qualities, it also has many
medicinal properties. Fortifying and
antiseptic, thyme still relieves multiple
disorders, particularly breathing disorders.
(Hossain,2013)
Thyme has pink flowers that attract
bees and confer their honey a special
flavor.
TAXONOMY
Domain: Eukarya
Kingdom: Plantae
Class: Magnoliopsida
Order: Lamiales
Family: Lamiaceae
Genus: Thymus L.
Scientific name: Thymus vulgaris L.
Common names: Thym (French), Garden
thyme (English), Thymian (German),
Timo (Italian), Zatr (Arabic)
Conservation status: There are no
conservation measures.
Habitat: Dry slopes, rocks and maquis.
Always found on clay or limestone soils.
Key Uses: Thyme is used for cough and
bronchitis as it produces expectoration and
reduces bronchial spasm. It also makes a
good use in indigestion, gastritis, and
diarrhea.
Known hazards: Avoid in inflammatory
disease of the gastrointestinal tract.
Internal use contraindicated especially in
pregnancy. Caution if sensitive to grasses.
(Anon-2010, 2012, 2014, 2015, katzer-
2003, Khela-2014)
CURRENT RESEARCH
• A complex solution: Thyme is another
aromatic member of the mint family. In
this case, its oils, when ingested, help to
relieve congestion and infection in the
respiratory tract. The herb factors into
many a good recipe for cough syrup.
(Nezhadali et al, 2013)
• Mechanism of action: It is thought that
the phenolic compounds of thyme exert
antibacterial activity by complexing with
the bacterial membrane proteins.
Bronchospasmolysis is attributed to the
flavonoids thymonin, cirsilineol and 8-
methoxycirsilineol. Antioxidative effects
of thyme oil have been attributed mainly
to its phenolic constituents (thymol and
carvacrol). (Hossain et al, 2013)
TRADITIONAL & CURRENT USES
Infections: Thyme is good against
bronchitis, pertussis, and pleurisy. The
infusion treats benign infections of the
throat and bronchi
Asthma and hay fever: Thyme is
prescribed to asthmatic children. It is
effective in case hay fever.
Anthelmintic: Thyme is prescribed to
children as an anthelmintic.
Stomach ulcer: Thyme extracts have a
powerful antibacterial effect against
H. pylori, a bacterium often linked to
stomach ulcers.
Other uses: It soothes insect’s bites
when applied on the skin. It is used
in sciatic pain or rheumatoid arthritis. It
also treats herpes, athlete's foot, mouth
ulcers, fungal infections, scabies and lice.
(Anon-2014, 2015, Komaki-2015)
PART USED
Fresh aerial
parts
Fresh leaves
The aerial parts harvested
in summer contain
essential oil with
antiseptic properties.
Dried aerial parts
PREPARATION AND
USAGE
Infusion:
During
cold, take
50 ml 3
times per
day.
Essential Oil:
Against scabies,
should dilute and
then stamp the
infected area.
Syrup:
Against cough;
take 20ml thrice
per day
THYMUS VULGARIS
8
REFERENCES
Web links
ANON, 2010. Thyme. Doctor Schar [online]. Available from: http://doctorschar.com/archives/thyme-
thymus-vulgare/ [Accessed September 2015].
ANON, 2012. Thymus vulgaris L. Plants for a future [online]. Available from:
http://www.pfaf.org/user/plant.aspx?LatinName=Thymus+vulgaris [Accessed September 2015].
ANON, 2012. Thymus vulgaris. Southern Cross University [online]. Available from:
http://scu.edu.au/scps/index.php/128/ [Accessed September 2015].
ANON, 2014. Thyme, Garden. Botanical.com [online]. Available from:
https://www.botanical.com/botanical/mgmh/t/thygar16.html [Accessed September 2015].
ANON, 2015. Thyme. Ayurvedic Herbs [online]. Available from:
http://www.indianmirror.com/ayurveda/thyme.html [Accessed September 2015].
KATZER, G., 2003. Thyme (Thymus vulgaris L.). Spice Pages [online]. Available from:
http://gernot-katzers-spice-pages.com/engl/Thym_vul.html [Accessed September 2015].
KHELA, S. 2014. Thymus vulgaris. Red List of Threatened Species [online]. Available from:
http://www.iucnredlist.org/details/203348/0 [Accessed 11 September 2015].
Journals
HOSSAIN, M.A., et al., 2013. Study of total phenol, flavonoids contents and phytochemical
screening of various leaves crude extracts of locally grown Thymus vulgaris. Asian Pacific Journal of
tropical biomedicine; 3(9), 705-710.
http://www.sciencedirect.com/science/article/pii/S2221169113601422
KOMAKI, A., et al., 2015. Study of the effect of extract of Thymus vulgaris on anxiety in male rats.
Journal of Traditional and Complementary Medicine.
http://www.sciencedirect.com/science/article/pii/S2225411015000188
NEZHADALI, A., et al., 2014. Chemical variation of leaf essential oil at different stages of plant
growth and in vitro antibacterial activity of Thymus vulgaris Lamiaceae, from Iran. Beni-Suef
University Journal of Basic and Applied Sciences; 3(2), 87-92.
http://www.sciencedirect.com/science/article/pii/S2314853514000304
ZINGIBER OFFICINALE
9
Zingiber officinale
MAIN COMPONENTS
• Essential Oil (1 – 2%) and
derived sesquiterpenes
• Phenols (glycerol, gingerol)
• Cinnamic acid
• Oleoresin (mixture of
essential oil and resin)
MAIN EFFECTS
• Anti-
inflammatory
• Antiemetic
• Stimulant
• Antiseptic
• Soothes cough
• Promotes
elimination of
intestinal gases
Widespread spice and condiment,
GINGER is the one of the most
employed remedy worldwide. Since
ancient time, it was very popular in
Asia and at Middle Age, Europeans
believed that it came from the
Garden of Eden. Ginger relieves
morning and travel sickness and
cures circulatory problems. Fresh, it
has a spicy and slightly acidic taste.
(Gupta et al, 2014).
Ginger is effective in case of
gastrointestinal disturbances.
TAXONOMY
Class: Equisetopsida
Subclass: Magnoliidae
Superorder: Lilianae
Order: Zingiberales
Family: Zingiberaceae
Genus: Zingiber
Scientific name: Zingiber officinale
R.
Common name: ginger (English);
gingembre (French); singabera
(Sanskrit); zenzero (Italian);
gingiber (Latin); zingiberi (Greek).
Conservation status: Least concern.
Habitat: Humid, partly-shaded
habitats in the tropics and
subtropics.
Key Uses: Food and drink,
medicine, cosmetics.
Known hazards: Ginger may cause
allergic reactions when applied to
the skin. Pregnant women should
use it with caution as its safety is
not yet confirmed.
(Anon-2011, 2014, 2015)
CURRENT RESEARCH
• Therapeutic effects: According to various
studies, the therapeutic actions of ginger are
greatly due to the oleoresin and essential oil
that it contains. The sharp taste and stimulant
properties of the plant come from gingerol, a
bitter component that forms when the root is
dried, which is more irritating and bitter than
components from fresh rhizome. (Imtiyaz et al,
2013)
• Antiemetic: Ginger is very effective against
travel sickness. Experimental tests performed in
1990 have established that it treats
postoperative nausea better than conventional
medicine.
• Antiseptic: In China, 70% of patients affected
by dysentery would have been cured by ginger.
TRADITIONAL & CURRENT USES
Digestive disturbances: Ginger is very effective
in case of indigestions, nausea (usually morning
sickness), flatulence, colitis, travel sickness and
also against gastrointestinal infections (due to
certain food poisoning) due to its antiseptic
properties.
Circulatory problems: Ginger is an effective
remedy against degeneration of organs and
when the body’s extremities are poorly irrigated
since it improves blood circulation in
capillaries. Ginger also increases arterial
pressure, stimulate sweating and reduces fever.
Respiratory problems: Ginger alleviates cough
and treats flu and other respiratory diseases.
“Sheng join”: In China, fresh ginger is
prescribed in case of chills, fever, headache and
muscular pain while dried ginger is given
against cold.
(Chang et al-2013, Baliga et al-2015, Anon-
2015)
PART USED
Dried Rhizome
Fresh
Rhizome
PREPARATION AND
USAGE
Rhizome
contains a
high amount
of essential
oil with
stimulant
effects.
Ginger essential
Oil against
arthritis. Apply 5
diluted drops in
20 drops of sweet
almond oil on
painful zones.
In case of morning sickness, 1
Ginger Capsule of 75mg is taken
every hour and to facilitate
digestion, 30 drops of Ginger
Tincture are taken in water twice
per day.
Ginger
Infusion for
nausea. Drink
1 cup 3 times
per day.
ZINGIBER OFFICINALE
10
REFERENCES
Web links
ANON, 2011. Ginger (Zingiber officinale). Chamberlin’s [online]. Available from:
http://www.chamberlins.com/ns/DisplayMonograph.asp?storeID=2cb86c7b36be4cfd914079104818c
49b&DocID=bottomline-ginger [Accessed September 2015].
ANON, 2014. Ginger (Zingiber officinale). MedicineNet.com [online]. Available from:
http://www.medicinenet.com/ginger_zingiber_officinale-oral/article.htm [Accessed September
2015].
ANON, 2015. Ginger. Mr Ginseng [online]. Available from: http://en.mr-ginseng.com/ginger/
[Accessed September 2015].
ANON, 2015. Zingiber officinale (ginger). Kew Royal Botanical gardens [online]. Available from:
http://www.kew.org/science-conservation/plants-fungi/zingiber-officinale-ginger [Accessed 6
September 2015].
ANON, 2015. Zingiber officinale. National Tropical Botanical Garden [online]. Available from:
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Journals
GUPTA, S.K. and SHARMA, A., 2014. Medicinal properties of Zingiber officinale Roscoe – A
Review. Journal of Pharmacy and Biological Sciences; 9(5), 124-129.
IMTIYAZ, S. et al., 2013. Zingiber officinale Rosc.: A traditional herb with medicinal properties.
Humanitas Traditional Medicine; 3(4), 1-7.
Atashak, S., Peeri, M., Azarbayjani, M. A. and Stannard, S. R. (2014) ‘Effects of ginger ()
supplementation and resistance training on some blood oxidative stress markers in obese men’,
Journal of Exercise Science & Fitness, 12(1), pp. 26–30. doi: 10.1016/j.jesf.2014.01.002.
Baliga, M. S., Latheef, L., Haniadka, R., Fazal, F., Mane, P. P., Kalekhan, F. and Chacko, J. (2015)
‘Chapter 12 – Ginger ( Roscoe) in the Treatment of Osteoarthritis’, Foods and Dietary Supplements in
the Prevention and Treatment of Disease in Older Adults, , pp. 111–117. doi: 10.1016/B978-0-12-
418680-4.00012-9.
Chang, J. S., Wang, K. C., Yeh, C. F., Shieh, D. E. and Chiang, L. C. (2013) ‘Fresh ginger () has anti-
viral activity against human respiratory syncytial virus in human respiratory tract cell lines’, Journal
of Ethnopharmacology, 145(1), pp. 146–151. doi: 10.1016/j.jep.2012.10.043.

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Monographs of Allium sativum, Apium graveolens, Citrus limon, Thymus vulgaris, Zingiber officinale

  • 1. UNIVERSITY OF MAURITIUS Bachelor of Pharmacy Year 4 Pharmacognosy 4 Monographs of 5 Plants Presented by: Naraino Majie Nabiilah-1216824 Joorawon Svenia-1217636 Date of Submission: 14th September 2015
  • 2. Monographs on: Page 1. Allium sativum 1 2. Apium graveolens 3 3. Citrus limon 5 4. Thymus vulgaris 7 5. Zingiber officinale 9
  • 3.
  • 4. ALLIUM SATIVUM 1 Allium sativum MAIN COMPONENTS • Essential Oil (disulfide diallyl, allicme) • Carbohydrates • Selenium • Vitamins A, B, C and E • Sulfur Compounds MAIN EFFECTS • Antibiotic • Expectorant • Active sweating • Hypotensor • Reduces blood clots • Hypoglycemic • Anthelmintic GARLIC is the medicinal plant par excellence. It is safe for home use and proves effective to treat multiple of health problems; it fights against nose, throat and bronchi infections, reduced cholesterol levels and soothes circulatory disorders, such as hypertension. Hypoglycemic, garlic is a valuable supplement food for diabetics. (Ayaz et al, 2007) Garlic, very appreciated in the kitchen, is grown for commercial purposes TAXONOMY Class: Equisetopsida Subclass: Magnoliidae Superorder: Lilianae Order: Asparagales Family: Amaryllidaceae Genus: Allium Scientific name: Allium sativum L. Common name: garlic (English); ajo (Spanish); ail (French); arishtha, lashuna (Sanskrit); lasan (Hindu and Gujarat); vellaipundu (Tamil). Conservation status: Not considered to be threatened. Habitat: Rocky valleys, riverbeds, streambeds and gullies. Key Uses: Food and drink, medicine, pest control. Known hazards: Adverse effects including a burning sensation in the mouth and intestine, sickness, and odour from the breath and the body. Skin reactions have also been reported. Garlic may interfere with some prescribed medicines. (Anon-2014, Ayaz et al-2007, Anon-2010) CURRENT RESEARCH • A complex solution: The therapeutic effects of garlic have been mentioned in more than thousand scientific articles. Garlic lowers lipid levels and cholesterol in the blood; it prevents the formation blood clots, reduces blood pressure and also reduces the blood sugar and exerts antibiotic action. (Jangam et al, 2014) • Mechanism of action: Chemical analysis in the 1800s attributed garlic's activity to the sulfur containing garlic oil. In the mid 1900s an American chemist named the strong smelling liquid "allicin". The sulfur compound alliin (S-allyl-l-cysteine sulfoxide) produces allicin (diallyl thiosulfinate) via the enzyme allinase when the bulb is crushed or ground. Other sulfur compounds, peptides, steroids, terpenoids, flavonoids, and phenols have increasingly been identified as possible active ingredients as allicin is metabolized. The exact mechanism of action underlying garlic's effects remains unknown and may vary according to the preparation and the therapeutic effect. (Anon, 2011) TRADITIONAL & CURRENT USES A traditional remedy: Before the invention of antibiotics, garlic was used to treat all kinds of diseases, from tuberculosis to typhoid fever. It was also used for dressing wounds during WWI. Bronchial Diseases: Garlic is great in case of bronchial infections and treats colds as well as ear infections. The digestive tract: Garlic treats diseases of the digestive system. It rids of the intestinal parasites. The circulatory system: Garlic prevents circulatory disorders and prevents their developments by thinning the blood. It also decreases cholesterol level. Other uses: Garlic is used against infections; it enhances the action of chemical antibiotics and avoids side effects. It also reduces blood glucose, as well as helps patients suffering from diabetes mellitus. PART USED Bulbs Cloves Fresh Plant PREPARATION AND USAGE These parts have been used since centuries in medicine and cooking for its tonic properties. Garlic Syrup against cough; take 1 spoon every 3 hours Minced cloves to decrease cholesterol and strengthen immune system These beads contain garlic oil. This increases the resistance of the body to infection.
  • 5. ALLIUM SATIVUM 2 REFERENCES Web links ANON, 2010. Garlic (Allium sativum). Sigma-Aldrich [online]. Available from: http://www.sigmaaldrich.com/life-science/nutrition-research/learning-center/plant-profiler/allium- sativum.html [Accessed September 2015]. ANON, 2011. Garlic. Mr Ginseng [online]. Available from: http://en.mr-ginseng.com/garlic/ [Accessed September 2015]. ANON, 2014. Garlic (Allium Sativum L.). MedicineNet.com [online].Available from: http://www.medicinenet.com/garlic_allium_sativum_l-oral/article.htm [Accessed September 2015]. ANON, 2015. Allium sativum (garlic). Kew Royal Botanic Gardens [online]. Available from: http://www.kew.org/science-conservation/plants-fungi/allium-sativum-garlic [Accessed September 2015]. Journals AYAZ, E. and ALPSOY, H.C., 2007. Garlic (Allium sativum) and traditional medicine. PubMed.gov; 31(2), 145-149. http://www.ncbi.nlm.nih.gov/pubmed/17594659 JANGAM, G.B. and BADOLE, S.L., 2014. Garlic (Allium sativum): Role in metabolic disorder. Polyphenols in human health and disease; 1(46), 611-614. http://www.sciencedirect.com/science/article/pii/B9780123984562000463 SULERIA, H.A.R., et al., 2015. Garlic (Allium sativum) : diet based therapy of 21st century – a review. Asian Pacific Journal of tropical disease; 5(4), 271-278. http://www.sciencedirect.com/science/article/pii/S2222180814607829 SUNG, S., et al., 2014. Effects of Allium sativum essence oil as antimicrobial agent for food packaging plastic film. Innovative Food Science & Emerging Technologies; 26, 406-414. http://www.sciencedirect.com/science/article/pii/S1466856414000800
  • 6.
  • 7. APIUM GRAVEOLENS 3 Apium graveolens var. graveolens Celery is a plant used in both medicine and cooking. TAXONOMY MAIN COMPONENTS •Essential Oil (1.5 to 3%) •Coumarins •Furanocoumarins (bergapten) •Flavonoids (apune) MAIN EFFECTS •Antirheumatic •Antispasmodic •Diuretics •Hypotensive •Antiseptic •Anti- inflammatory Kingdom: Plantae (unranked): Angiosperms Order: Apiales Family: Apiaceae Genus: Apium Species: A. graveolens MOST COMMONLY USED as a vegetable than as medicaments, the branches and seeds of celery treat disorders such as rheumatism or arthritis, celery helps cleanse the body by removing toxins. Its seeds effectively eliminate intestinal gas and they relieve bloating related abdominal pain. (Tobyn et al, 2011) Scientific name: Apium graveolens L. Common name: celery (English); apio (Spanish); céleri (French); shalari (Hindu and Gujarat); sedano (Italian). Conservation status: Not considered to be threatened except in Sweden. Habitat: Marshy areas, terrestrial, fresh water. Key Uses: Vegetable, medicine, dietary herb (China). Known hazards: Adverse effects include skin inflammation and sensitivity to the sun. Unsafe for pregnant women, people with bleeding disorder, kidney problems and low BP. (Anon- 2005, 2014, 2015) CURRENT RESEARCH • A complex solution: The essential oil provides a calming effect on the nervous system. Seed extracts may lower blood lipid levels. Chinese Studies indicate that the oil is effective against hypertension. Celery is a rich source of phenolic phytonutrients that have antioxidant and anti-inflammatory properties. (Fuchs et al, 2012) • Mechanism of action: Celery contains phenols and furocoumarins (psoralens). Celery seed oil contains the natural phthalide sedanolide which showed protective effects against hydrogen peroxide H2O2 and tert-butyl hydroperoxide (tBOOH)-induced toxicity in HepG2 and CaCo-2 cells. Celery tuber also contains methoxsalen (8-methoxypsoralen) and 5-methoxypsoralen and the allergen profilin (Api g 1), which shows high homology to birch pollen profilin. (Madhavi et al, 2013) TRADITIONAL AND CURRENT USES • An antique use: The use celery is cultivated for at least 3000 years, particularly in Egypt. In the fifth century BC, the Chinese already knew about this plant. During history, celery has always been consumed as food and at various times, the whole plant and seeds were used for medicinal purpose. • The purifying properties: Today, the seeds are used to treat gout and certain rheumatism. They get the kidneys rid of their waste and reduce the acidity of organ. Seeds treat arthritis by detoxifying the body and improving blood flow to the muscles and joints. • A diuretic agent: Celery seeds have a mild diuretic action and great antiseptic effect. They are effective against cystitis since they disinfect bladder. PART USED PREPARATION AND USAGE Leaves All parts have high nutritive values but the seeds are mostly used in medicine. Detoxifying drink; take one cup of celery juice and carrot juice once per day. Seed infusion to treat gout and arthritis; take one cup with 1.5g of seed every day. Powdered seeds to treat arthritis; take one teaspoon each day.
  • 8. APIUM GRAVEOLENS 4 REFERENCES Web links ANON, 2005. Celery. WebMD [online]. Available from: http://www.webmd.com/vitamins- supplements/ingredientmono-882-celery.aspx?activeingredientid=882&activeingredientname=celery [Accessed September 2015]. ANON, 2015. Apium graveolens. Red List of Threatened Species [online]. Available from: http://www.iucnredlist.org/details/164203/0 [Accessed September 2015]. ANON, 2015. Celery (Apium graveolens). Sigma-Aldrich [online]. Available from: http://www.sigmaaldrich.com/life-science/nutrition-research/learning-center/plant-profiler/apium- graveolens.html [Accessed September 2015]. EHRLICH, S.D., 2015. Celery seed. Milton S. Hershey Medicinal Center [online]. Available from: http://pennstatehershey.adam.com/content.aspx?productId=107&pid=33&gid=000231 [Accessed September 2015]. MURRAY, M.T., 2014. Celery and Celery seed extract are powerful, Proven healers. DoctorMurray.com [online]. Available from: http://doctormurray.com/celery-and-celery-seed-extract- are-powerful-proven-healers/ [Accessed September 2015]. Journals FUCHS, M., et al., 2012. Development and validation of a novel real-time PCR method for the detection of celery (Apium graveolens) in food. Food Chemistry; 130(1), 189-195. http://www.sciencedirect.com/science/article/pii/S0308814611009526 MADHAVI, D, et al., 2013. A pilot study to evaluate the antihypertensive effect of a celery extract in mild to moderate hypertensive patients. Natural Medicine Journal; 5(4). http://naturalmedicinejournal.com/journal/2013-04/pilot-study-evaluate-antihypertensive-effect- celery-extract-mild-moderate MODARESI, M., et al., 2012. The effects of celery (Apium graveolens) extract on the reproductive hormones in male mice. APCBEE Procedia; 4(2012), 99-104. http://www.sciencedirect.com/science/article/pii/S221267081200187X TOBYN, G, DENHAM, A. and WHITELEGG, M., 2011. Apium graveolens, wild celery. Medical Herbs; 9, 79-89. http://www.sciencedirect.com/science/article/pii/B9780443103445000148
  • 9.
  • 10. CITRUS LIMON 5 Citrus limon MAIN COMPONENTS • Essential Oil (2 – 5% in fruit peel), sesquiterpenes, terpenoids, aldehydes, esters • Coumarins • Flavonoids • Vitamins MAIN EFFECTS • Antibacterial • Antioxidant • Anti-rheumatic • Antiseptic • Reduces fever LEMON is a major natural remedy. Common food with numerous medicinal virtues, it is rich in vitamin C and favours resistance against infections which helps to treat influenza and colds. It is consumed in preventive way in case of gastritis, circulatory problems and atherosclerosis. (Anon, 2006) Lemon treats scurvy (lack of vitamin C). TAXONOMY Class: Magnoliophyta Subclass: Dilleniidae Superorder: Violanae Order: Sapindales Family: Rutaceae Genus: Citrus Scientific name: Citrus limon L. Common name: lemon (English); citron (French); limone (Italian); limon (Creole); līmūn (Arabic); nimbū (Sanskrit). Conservation status: Least concern. Habitat: Mediterranean region and subtropical parts of the world. Key Uses: Food and drink, medicine, cosmetics. Known hazards: Sore throat, nausea, it may taste bitter after a while. (Anon- 2006, 2011,2012) CURRENT RESEARCH • A complex solution: Its most prominent component, limonene, is likely the key to its potency, found in many citrus oils but none so strongly as lemon. Its cancer-fighting antioxidant power is impressive, as well. (G. M. Et al, 2010) • Mechanism of action: Its mode of action is not clear. It acts in one or more different way to exert its pharmacologic effect. (Bailey, 1976) TRADITIONAL & CURRENT USES Famous medication: Spanish folk medicine attributes so much therapeutic values to lemon that entire books have been devoted to it. Established properties: Once digested, lemon has an antacid effect which makes it effective in case of rheumatoid arthritis which favours acidity. The essential oil is antiseptic and antibacterial. The flavonoids present strengthen the inner wall of blood vessels and favour the disappearance of varicose veins and reduction of bruises. Preventive action: Lemon is a distinguished preventive remedy. Its antiseptic and detoxifying properties make it an important ally for persons prone to atherosclerosis, fever and infectious diseases of the stomach, liver and intestine. Its action on the wall of blood vessels helps to prevent circulatory problems and bleeding gums. It is also an excellent and effective tonic against certain chronic diseases. Stimulate veins’ walls: The fruit and white peel prevent atherosclerosis and weakness of capillaries. Juice: Lemon juice fights colds, flu and infections. It stimulates liver detoxification and improves appetite. It is a tonic of the liver and the pancreas and it fights against ulcers and rheumatoid arthritis. As gargle, it treats sore throat, gum disease and mouth ulcer. For external use, it is applied on acne, athlete’s foot, bites, sunburn and warts. (Lopes et al-2011, Freitas et al-2014, Nakajima et al-2014) PART USED Fruit and peel improve circulation and strengthen resistance against infections. White peel and zest contain essential oil and most flavonoids. PREPARATION AND USAGE Lemon contains twice as much as vitamin C as orange. Lemon essential Oil. Dilute 5 drops in 1 teaspoon of neutral oil and apply on mouth ulcers. Remedy against colds; mix 20ml of lemon juice with 50ml of hot water and add 1 crushed clove of garlic together with 1 pinch of cinnamon. Drink the mixture 3 times per day. Lemon juice for throat irritation. Mix 20ml of lemon juice with 20ml of hot water and use as gargle.
  • 11. CITRUS LIMON 6 REFERENCES Web links ANON, 2006. Citrus limon. Learn 2 grow [online]. Available from: http://www.learn2grow.com/plants/citrus-limon/ [Accessed September 2015]. ANON, 2011. Citrus limon L. Taxonomy for plants [online]. Available from: http://www.ars- grin.gov/cgi-bin/npgs/html/taxon.pl?10732 [Accessed September 2015]. ANON, 2012. Citrus limon – L. Plants for a future [online]. Available from: http://www.pfaf.org/user/Plant.aspx?LatinName=Citrus+limon [Accessed September 2015]. BAILEY, et al., 1976. Lemon. Encyclopedia of Life [online]. Available from: http://eol.org/pages/582200/overview [Accessed September 2015]. KASRAOUI, F., 2006. Le citronnier. Kasroui.com Le site officiel [online]. Available from: http://www.kasraoui.com/Secteur-Agricole/Agrumes-Citronnier.html [Accessed 10 September 2015]. Journals GONZALEZ-MOLINA, E. et al., 2010. Natural bioactive compounds of Citrus limon for food and health. Journal of Pharmaceutical and biomedicinal analysis. 51(2), 327-345. LOPES CAMPÊLO, L.M. et al., 2011. Antioxidant and Antinociceptive effects of Citrus limon essential oil in mice. Journal of Biomedicine and Biotechnology. 2011(2011), 1-8. Freitas, E. S., Viana, M. D. M., Silva-Neto, G. J., Oliveira, L. M. S., Duzzioni, M., Castro, O. W., Ferro, J. M. S., Barreto, E., Campesatto, E. A. and Alexandre-Moreira, M. S. (2014) ‘026 — (FRE0127) Motor performance evaluation of mice treated with essential oil’, Epilepsy & Behavior, 38, pp. 192–193. doi: 10.1016/j.yebeh.2014.08.059. Nakajima, V. M., Macedo, G. A. and Macedo, J. A. (1205) ‘Citrus bioactive phenolics: Role in the obesity treatment’, LWT - Food Science and Technology, 59(2), pp. 1205–1212. doi: 10.1016/j.lwt.2014.02.060.
  • 12.
  • 13. THYMUS VULGARIS 7 Thymus vulgaris MAIN COMPONENTS • Essential Oil (thymol, carvacrol, linalol) • Flavonoids • Phenolics MAIN EFFECTS • Antiseptics • Tonic • Muscle relaxant • Expectorant • Vermifuge • Antioxidant Thyme is characteristic to the Mediterranean flora; it is also known as "farigoule" in southern France. Known for its aromatic qualities, it also has many medicinal properties. Fortifying and antiseptic, thyme still relieves multiple disorders, particularly breathing disorders. (Hossain,2013) Thyme has pink flowers that attract bees and confer their honey a special flavor. TAXONOMY Domain: Eukarya Kingdom: Plantae Class: Magnoliopsida Order: Lamiales Family: Lamiaceae Genus: Thymus L. Scientific name: Thymus vulgaris L. Common names: Thym (French), Garden thyme (English), Thymian (German), Timo (Italian), Zatr (Arabic) Conservation status: There are no conservation measures. Habitat: Dry slopes, rocks and maquis. Always found on clay or limestone soils. Key Uses: Thyme is used for cough and bronchitis as it produces expectoration and reduces bronchial spasm. It also makes a good use in indigestion, gastritis, and diarrhea. Known hazards: Avoid in inflammatory disease of the gastrointestinal tract. Internal use contraindicated especially in pregnancy. Caution if sensitive to grasses. (Anon-2010, 2012, 2014, 2015, katzer- 2003, Khela-2014) CURRENT RESEARCH • A complex solution: Thyme is another aromatic member of the mint family. In this case, its oils, when ingested, help to relieve congestion and infection in the respiratory tract. The herb factors into many a good recipe for cough syrup. (Nezhadali et al, 2013) • Mechanism of action: It is thought that the phenolic compounds of thyme exert antibacterial activity by complexing with the bacterial membrane proteins. Bronchospasmolysis is attributed to the flavonoids thymonin, cirsilineol and 8- methoxycirsilineol. Antioxidative effects of thyme oil have been attributed mainly to its phenolic constituents (thymol and carvacrol). (Hossain et al, 2013) TRADITIONAL & CURRENT USES Infections: Thyme is good against bronchitis, pertussis, and pleurisy. The infusion treats benign infections of the throat and bronchi Asthma and hay fever: Thyme is prescribed to asthmatic children. It is effective in case hay fever. Anthelmintic: Thyme is prescribed to children as an anthelmintic. Stomach ulcer: Thyme extracts have a powerful antibacterial effect against H. pylori, a bacterium often linked to stomach ulcers. Other uses: It soothes insect’s bites when applied on the skin. It is used in sciatic pain or rheumatoid arthritis. It also treats herpes, athlete's foot, mouth ulcers, fungal infections, scabies and lice. (Anon-2014, 2015, Komaki-2015) PART USED Fresh aerial parts Fresh leaves The aerial parts harvested in summer contain essential oil with antiseptic properties. Dried aerial parts PREPARATION AND USAGE Infusion: During cold, take 50 ml 3 times per day. Essential Oil: Against scabies, should dilute and then stamp the infected area. Syrup: Against cough; take 20ml thrice per day
  • 14. THYMUS VULGARIS 8 REFERENCES Web links ANON, 2010. Thyme. Doctor Schar [online]. Available from: http://doctorschar.com/archives/thyme- thymus-vulgare/ [Accessed September 2015]. ANON, 2012. Thymus vulgaris L. Plants for a future [online]. Available from: http://www.pfaf.org/user/plant.aspx?LatinName=Thymus+vulgaris [Accessed September 2015]. ANON, 2012. Thymus vulgaris. Southern Cross University [online]. Available from: http://scu.edu.au/scps/index.php/128/ [Accessed September 2015]. ANON, 2014. Thyme, Garden. Botanical.com [online]. Available from: https://www.botanical.com/botanical/mgmh/t/thygar16.html [Accessed September 2015]. ANON, 2015. Thyme. Ayurvedic Herbs [online]. Available from: http://www.indianmirror.com/ayurveda/thyme.html [Accessed September 2015]. KATZER, G., 2003. Thyme (Thymus vulgaris L.). Spice Pages [online]. Available from: http://gernot-katzers-spice-pages.com/engl/Thym_vul.html [Accessed September 2015]. KHELA, S. 2014. Thymus vulgaris. Red List of Threatened Species [online]. Available from: http://www.iucnredlist.org/details/203348/0 [Accessed 11 September 2015]. Journals HOSSAIN, M.A., et al., 2013. Study of total phenol, flavonoids contents and phytochemical screening of various leaves crude extracts of locally grown Thymus vulgaris. Asian Pacific Journal of tropical biomedicine; 3(9), 705-710. http://www.sciencedirect.com/science/article/pii/S2221169113601422 KOMAKI, A., et al., 2015. Study of the effect of extract of Thymus vulgaris on anxiety in male rats. Journal of Traditional and Complementary Medicine. http://www.sciencedirect.com/science/article/pii/S2225411015000188 NEZHADALI, A., et al., 2014. Chemical variation of leaf essential oil at different stages of plant growth and in vitro antibacterial activity of Thymus vulgaris Lamiaceae, from Iran. Beni-Suef University Journal of Basic and Applied Sciences; 3(2), 87-92. http://www.sciencedirect.com/science/article/pii/S2314853514000304
  • 15.
  • 16. ZINGIBER OFFICINALE 9 Zingiber officinale MAIN COMPONENTS • Essential Oil (1 – 2%) and derived sesquiterpenes • Phenols (glycerol, gingerol) • Cinnamic acid • Oleoresin (mixture of essential oil and resin) MAIN EFFECTS • Anti- inflammatory • Antiemetic • Stimulant • Antiseptic • Soothes cough • Promotes elimination of intestinal gases Widespread spice and condiment, GINGER is the one of the most employed remedy worldwide. Since ancient time, it was very popular in Asia and at Middle Age, Europeans believed that it came from the Garden of Eden. Ginger relieves morning and travel sickness and cures circulatory problems. Fresh, it has a spicy and slightly acidic taste. (Gupta et al, 2014). Ginger is effective in case of gastrointestinal disturbances. TAXONOMY Class: Equisetopsida Subclass: Magnoliidae Superorder: Lilianae Order: Zingiberales Family: Zingiberaceae Genus: Zingiber Scientific name: Zingiber officinale R. Common name: ginger (English); gingembre (French); singabera (Sanskrit); zenzero (Italian); gingiber (Latin); zingiberi (Greek). Conservation status: Least concern. Habitat: Humid, partly-shaded habitats in the tropics and subtropics. Key Uses: Food and drink, medicine, cosmetics. Known hazards: Ginger may cause allergic reactions when applied to the skin. Pregnant women should use it with caution as its safety is not yet confirmed. (Anon-2011, 2014, 2015) CURRENT RESEARCH • Therapeutic effects: According to various studies, the therapeutic actions of ginger are greatly due to the oleoresin and essential oil that it contains. The sharp taste and stimulant properties of the plant come from gingerol, a bitter component that forms when the root is dried, which is more irritating and bitter than components from fresh rhizome. (Imtiyaz et al, 2013) • Antiemetic: Ginger is very effective against travel sickness. Experimental tests performed in 1990 have established that it treats postoperative nausea better than conventional medicine. • Antiseptic: In China, 70% of patients affected by dysentery would have been cured by ginger. TRADITIONAL & CURRENT USES Digestive disturbances: Ginger is very effective in case of indigestions, nausea (usually morning sickness), flatulence, colitis, travel sickness and also against gastrointestinal infections (due to certain food poisoning) due to its antiseptic properties. Circulatory problems: Ginger is an effective remedy against degeneration of organs and when the body’s extremities are poorly irrigated since it improves blood circulation in capillaries. Ginger also increases arterial pressure, stimulate sweating and reduces fever. Respiratory problems: Ginger alleviates cough and treats flu and other respiratory diseases. “Sheng join”: In China, fresh ginger is prescribed in case of chills, fever, headache and muscular pain while dried ginger is given against cold. (Chang et al-2013, Baliga et al-2015, Anon- 2015) PART USED Dried Rhizome Fresh Rhizome PREPARATION AND USAGE Rhizome contains a high amount of essential oil with stimulant effects. Ginger essential Oil against arthritis. Apply 5 diluted drops in 20 drops of sweet almond oil on painful zones. In case of morning sickness, 1 Ginger Capsule of 75mg is taken every hour and to facilitate digestion, 30 drops of Ginger Tincture are taken in water twice per day. Ginger Infusion for nausea. Drink 1 cup 3 times per day.
  • 17. ZINGIBER OFFICINALE 10 REFERENCES Web links ANON, 2011. Ginger (Zingiber officinale). Chamberlin’s [online]. Available from: http://www.chamberlins.com/ns/DisplayMonograph.asp?storeID=2cb86c7b36be4cfd914079104818c 49b&DocID=bottomline-ginger [Accessed September 2015]. ANON, 2014. Ginger (Zingiber officinale). MedicineNet.com [online]. Available from: http://www.medicinenet.com/ginger_zingiber_officinale-oral/article.htm [Accessed September 2015]. ANON, 2015. Ginger. Mr Ginseng [online]. Available from: http://en.mr-ginseng.com/ginger/ [Accessed September 2015]. ANON, 2015. Zingiber officinale (ginger). Kew Royal Botanical gardens [online]. Available from: http://www.kew.org/science-conservation/plants-fungi/zingiber-officinale-ginger [Accessed 6 September 2015]. ANON, 2015. Zingiber officinale. National Tropical Botanical Garden [online]. Available from: http://ntbg.org/plants/plant_details.php?plantid=11651 [Accessed September 2015]. Journals GUPTA, S.K. and SHARMA, A., 2014. Medicinal properties of Zingiber officinale Roscoe – A Review. Journal of Pharmacy and Biological Sciences; 9(5), 124-129. IMTIYAZ, S. et al., 2013. Zingiber officinale Rosc.: A traditional herb with medicinal properties. Humanitas Traditional Medicine; 3(4), 1-7. Atashak, S., Peeri, M., Azarbayjani, M. A. and Stannard, S. R. (2014) ‘Effects of ginger () supplementation and resistance training on some blood oxidative stress markers in obese men’, Journal of Exercise Science & Fitness, 12(1), pp. 26–30. doi: 10.1016/j.jesf.2014.01.002. Baliga, M. S., Latheef, L., Haniadka, R., Fazal, F., Mane, P. P., Kalekhan, F. and Chacko, J. (2015) ‘Chapter 12 – Ginger ( Roscoe) in the Treatment of Osteoarthritis’, Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults, , pp. 111–117. doi: 10.1016/B978-0-12- 418680-4.00012-9. Chang, J. S., Wang, K. C., Yeh, C. F., Shieh, D. E. and Chiang, L. C. (2013) ‘Fresh ginger () has anti- viral activity against human respiratory syncytial virus in human respiratory tract cell lines’, Journal of Ethnopharmacology, 145(1), pp. 146–151. doi: 10.1016/j.jep.2012.10.043.