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Vascular Access for
Haemodialysis
Ahmed Halawa
Sheffield Kidney Institute
In Egypt
• Poorly planned
• Done by a junior surgeon, not usually
specialized
• At the end of the list
Renal replacement therapy
– Haemodialysis
– Peritoneal dialysis
– Transplantation
Haemodialysis
• Need a conduit that can be needled/used
frequently
– Autogenous arteriovenous fistula
– PTFE graft
– Tunnelled line
Formation of Fistula
• Multiple options
– Radial artery to
cephalic vein
– Brachial artery to
cephalic vein
– Basilic vein to brachial
artery (transposition)
– Long Saphenous vein
to superficial femoral
artery (transposition)
Formation of Fistula
What makes a good fistula?
A good fistula has:-
• Good long term patency
• Size >5mm
• Adequate blood flow >350ml/min
• Low revision/intervention rate
• Low infection rate
• Low thrombosis rate
Fistula Maturation
• An AVF forms a low resistance pathway
• Volume flow through fistula increases due
to low resistance
• Distal extremity perfusion is maintained by
increase in cardiac output
• Flow in proximal artery needs to increase
to meet demands of the AVF
• Normal brachial artery flow 50ml/min
Factors that lead to good fistula
• Arterial
• Size >1.6 mm
• Lack of calcification
• Flow pattern
Factors that lead to good fistula
• Venous
• >2.2 mm without
tourniquet
• No evidence of
stenosis/thrombosis
• Depth
• Central venous patency
PTFE Graft
PTFE Graft
Brachiobasilic Vein Transposition
Brachiobasilic Vein Transposition
Complications
Steal Syndrome
• Severe ischaemia 1-8% of access
procedures
• Chronic pain
• Tissue loss
• Non functioning extremity
• Graded 0 (no steal) to 3 (severe)
• Secondary to
• High fistula flow
• Poor collateral perfusion (particularly diabetics)
• Rarely inflow stenosis
Steal Syndrome
Steal Syndrome
Duplex Doppler ultrasound of the left antecubital fossa demonstrating
a significant steal syndrome. Blood enters the proximal brachial artery
(1) and >70% is shunted through the PTFE graft (3) with <30% flow
through the native distal artery (2).
Steal Syndrome
Management of Steal Syndrome
Management of Steal Syndrome
Management of Steal Syndrome
• Distal reconstruction
and interval ligation
(DRIL)
• Preferable to use vein
• Increased risk
thrombosis PTFE
• 9 case series
• Symptoms resolved 33
to 100%
• Improved 17 to 66%
• No change 1 series 11%
• DRIL patency 86 to
100%
Aneurysm
Pseudoaneurysm
Aneurysm and Pseudoaneurysm
Indications for revision/repair of AV fistula aneurysm:
• The skin overlying the fistula is (ischemic) compromised
• There is a risk of fistula rupture
• Available puncture sites are limited
indications for revision/repair of pseudoaneurysm formation :
• Symptomatic or threatens the viability of the overlying skin
• Evidence of infection
• Pseudoaneurysm that is enlarging in size or that exceeds twice the
diameter of the graft
• Limited number of cannulation sites
Cannulation through a pseudoaneurysm must be avoided
Venous Hypertension
Sign and symptoms:
severe upper limb edema
skin discoloration
access dysfunction
peripheral ischaemia with resultant fingertip ulceration.
In most cases, the underlying venous pathology follows
ipsilateral central venous catheter placement with
consequent venous stenosis.
Venous Hypertension
Venous Hypertension
Treatment
•Angioplasty of the stenosis
•Bypass
•Disconnection of the fistula
Infection
The second most common cause of AV access
failure (0-3% in AVF and 6%-25%in AV grafts)
Treatment:
AVFs: Local drainage and antibiotic therapy for
6 weeks
AV grafts: Antibiotic therapy and surgical
treatment (in most cases complete excision of
prosthetic graft)
Haematoma
Haematoma
• Small and not expanding Conserve
• Large or expanding Drainage
Buttonhole Technique
for
Cannulation of AV Fistulae
Buttonhole Structure
Needles – sharp and blunt
Buttonhole Technique
• Reuse same sites
each treatment with
blunt needles
• Must follow the
track/tunnel of the
original cannulation
Doppler Ultrasound Of The
Tunnel
Benefits for the patient
• Less painful – elimination of anesthetic
• Fewer infections
• Fewer missed needle sticks
• Fewer haematomas
• Cannulation of access takes less time
Why to offer the Buttonhole Technique?
• Prolong AV fistula life
• Decrease hospitalizations related to access
infections and complications
• Promote patient self-cannulation
• Decrease pain associated with needle
cannulation
Rope-Ladder Technique
for
Cannulation of AV Fistulae
Rope Ladder
Buttonhole vs Rope-Ladder
Am J Kidney Dis.
2014;64(6):918-936
References
• Atlas of Dialysis Vascular Access
http://c.ymcdn.com/sites/www.asdin.org/resource/resmgr/imported/atlas%20of%20dialysis
%20access.pdf
• Field A,Backwell J,Jaipersad A; et al,. Distal Revascularisation with Interval Ligation (DRIL): An
Experience. Ann R Coll Surg Engl. 2009 Jul; 91(5): 394–398
• Treatment of vascular steal syndrome Date written: August 2011: Christine Russel. Available
from: http://www.cari.org.au/Dialysis/dialysis%20vascular
%20access/Treatment_of_steal_syndrome.pdf
• van Hoek F, Scheltinga MR, Kouwenberg I et al. Steal in hemodialysis patients depends on type
of vascular access. European Journal of Vascular & Endovascular Surgery. 2006; 32: 710-7.
• Clinical Practice Recommendations for Use of Buttonhole Technique for Cannulation of
Arteriovenous Fistulae. Available from;
http://www.britishrenal.org/BritishRenalSociety/files/64/64c14da8-6738-4828-a326-
526c731ff565.pdf
• Ben Wong et al,. Buttonhole Versus Rope-Ladder Cannulation of Arteriovenous
Fistulas for Hemodialysis: A Systematic Review. Am J Kidney Dis. 2014;64(6):918-936
http://www.wanfang.gov.tw/Upload/WebDownLoadFile1201505141512177.pdf
Thank You

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Vascular access for haemodialysis prof. ahmed halawa

  • 1. Vascular Access for Haemodialysis Ahmed Halawa Sheffield Kidney Institute
  • 2. In Egypt • Poorly planned • Done by a junior surgeon, not usually specialized • At the end of the list
  • 3. Renal replacement therapy – Haemodialysis – Peritoneal dialysis – Transplantation
  • 4. Haemodialysis • Need a conduit that can be needled/used frequently – Autogenous arteriovenous fistula – PTFE graft – Tunnelled line
  • 5. Formation of Fistula • Multiple options – Radial artery to cephalic vein – Brachial artery to cephalic vein – Basilic vein to brachial artery (transposition) – Long Saphenous vein to superficial femoral artery (transposition)
  • 7. What makes a good fistula? A good fistula has:- • Good long term patency • Size >5mm • Adequate blood flow >350ml/min • Low revision/intervention rate • Low infection rate • Low thrombosis rate
  • 8. Fistula Maturation • An AVF forms a low resistance pathway • Volume flow through fistula increases due to low resistance • Distal extremity perfusion is maintained by increase in cardiac output • Flow in proximal artery needs to increase to meet demands of the AVF • Normal brachial artery flow 50ml/min
  • 9. Factors that lead to good fistula • Arterial • Size >1.6 mm • Lack of calcification • Flow pattern
  • 10. Factors that lead to good fistula • Venous • >2.2 mm without tourniquet • No evidence of stenosis/thrombosis • Depth • Central venous patency
  • 16. Steal Syndrome • Severe ischaemia 1-8% of access procedures • Chronic pain • Tissue loss • Non functioning extremity • Graded 0 (no steal) to 3 (severe) • Secondary to • High fistula flow • Poor collateral perfusion (particularly diabetics) • Rarely inflow stenosis
  • 18. Steal Syndrome Duplex Doppler ultrasound of the left antecubital fossa demonstrating a significant steal syndrome. Blood enters the proximal brachial artery (1) and >70% is shunted through the PTFE graft (3) with <30% flow through the native distal artery (2).
  • 22. Management of Steal Syndrome • Distal reconstruction and interval ligation (DRIL) • Preferable to use vein • Increased risk thrombosis PTFE • 9 case series • Symptoms resolved 33 to 100% • Improved 17 to 66% • No change 1 series 11% • DRIL patency 86 to 100%
  • 25. Aneurysm and Pseudoaneurysm Indications for revision/repair of AV fistula aneurysm: • The skin overlying the fistula is (ischemic) compromised • There is a risk of fistula rupture • Available puncture sites are limited indications for revision/repair of pseudoaneurysm formation : • Symptomatic or threatens the viability of the overlying skin • Evidence of infection • Pseudoaneurysm that is enlarging in size or that exceeds twice the diameter of the graft • Limited number of cannulation sites Cannulation through a pseudoaneurysm must be avoided
  • 26. Venous Hypertension Sign and symptoms: severe upper limb edema skin discoloration access dysfunction peripheral ischaemia with resultant fingertip ulceration. In most cases, the underlying venous pathology follows ipsilateral central venous catheter placement with consequent venous stenosis.
  • 28. Venous Hypertension Treatment •Angioplasty of the stenosis •Bypass •Disconnection of the fistula
  • 29. Infection The second most common cause of AV access failure (0-3% in AVF and 6%-25%in AV grafts) Treatment: AVFs: Local drainage and antibiotic therapy for 6 weeks AV grafts: Antibiotic therapy and surgical treatment (in most cases complete excision of prosthetic graft)
  • 31. Haematoma • Small and not expanding Conserve • Large or expanding Drainage
  • 34. Needles – sharp and blunt
  • 35. Buttonhole Technique • Reuse same sites each treatment with blunt needles • Must follow the track/tunnel of the original cannulation
  • 36. Doppler Ultrasound Of The Tunnel
  • 37. Benefits for the patient • Less painful – elimination of anesthetic • Fewer infections • Fewer missed needle sticks • Fewer haematomas • Cannulation of access takes less time
  • 38. Why to offer the Buttonhole Technique? • Prolong AV fistula life • Decrease hospitalizations related to access infections and complications • Promote patient self-cannulation • Decrease pain associated with needle cannulation
  • 41. Buttonhole vs Rope-Ladder Am J Kidney Dis. 2014;64(6):918-936
  • 42. References • Atlas of Dialysis Vascular Access http://c.ymcdn.com/sites/www.asdin.org/resource/resmgr/imported/atlas%20of%20dialysis %20access.pdf • Field A,Backwell J,Jaipersad A; et al,. Distal Revascularisation with Interval Ligation (DRIL): An Experience. Ann R Coll Surg Engl. 2009 Jul; 91(5): 394–398 • Treatment of vascular steal syndrome Date written: August 2011: Christine Russel. Available from: http://www.cari.org.au/Dialysis/dialysis%20vascular %20access/Treatment_of_steal_syndrome.pdf • van Hoek F, Scheltinga MR, Kouwenberg I et al. Steal in hemodialysis patients depends on type of vascular access. European Journal of Vascular & Endovascular Surgery. 2006; 32: 710-7. • Clinical Practice Recommendations for Use of Buttonhole Technique for Cannulation of Arteriovenous Fistulae. Available from; http://www.britishrenal.org/BritishRenalSociety/files/64/64c14da8-6738-4828-a326- 526c731ff565.pdf • Ben Wong et al,. Buttonhole Versus Rope-Ladder Cannulation of Arteriovenous Fistulas for Hemodialysis: A Systematic Review. Am J Kidney Dis. 2014;64(6):918-936 http://www.wanfang.gov.tw/Upload/WebDownLoadFile1201505141512177.pdf