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Management of
Anterior urethral strictures
AUA update series 2014
Summarized By
Mohammed T. Doukhi
MD,
TechnologyJordan university of Science &
outlines
◦ Introdution
◦ Epidemiology and etiology
◦ Diagnosis
◦ Treatment
◦ Complication
◦ Conclusion
introduction
Definition :
It is narrowing of the anterior urethral that
impedes flow and implies some degree of
spongiofibrosis is called stricture
Epidemilogy and etiology
Common in men
Older than 65 years old
Most common is idiopathic
2nd most common is iatrogenic
Ex. Cath,cystoscopy,TURP.
lichen sclerosus (PXO)
Diagnosis
 Urethral stricture typically present with
obstructive voiding symptoms
Such as
 Weak stream
 Incomplete voiding
 Cystitis
 Bladder stone
Hydronephrosis and renal failure (rare)
 Inability to pass catheter in a patient
otherwise asymptomatic
Investigation
 RUG
 MCUG
 U/S
 MRI
Treatment
:Urethral dilation
Using balloon dilator after placement of guidewire
under direct visualization to minimize the risk of
creating a false passage or rectal injury
Internal urethrotomy:
Using a cold-knife incision at 12 o’clock position
Foley catheter is left in place for 3 to 5 days
Cont, Treatment
Many believe that urethrotomy is more effective than
dilator,
randomized clinical trial of dilation vs. urethrotomy
revealed NO long-term difference in outcome.
Alternative technique such as resection the scar or
use of laser have not provide increase efficacy
Disadvantage of dilator and urethrotomy :
No benefit if
Stricture larger than 1 cm
Stricture in penile urethra
Intraurethral stents :
Intraurethral stents :
Cont, Treatment
Intraurethral stents :
Have been used to treat strictures.
Designed for incorporation into urethral mucosa
which appear to work best for short bulbar stricture.
Stent migration and re-stricture were reported
following insertion leading to more difficult
urethroplasty
is no longer available in the U.S.A®The Urolume
Cont, Treatmet
:Urothroplasty
Based in the location and caliber of the stricture,
urethroplasty can be performed either by excision of
the stricure with reanastomosis, or with graft or flap
Stricture within the penile urethra are rarely excised
because shortening the urethra may lead to penile
curvature.
Complications
Urethral dilation may lead to hematuria, false
passage and, rarely bladder perforation and rectal
injury
Urethrotomy may result in hematuria and false
passage. Epididymitis, prostatitis, penile curvature
and glans necrosis have also been reported
Immediate complication after
urethroplasty are uncommon but include
infection bleeding and thromboembolism
Cont, Complications
If urethroplasty is performed with the patient in high
lithotomy position, surgery for longer than 5 hours
has been associated with complications such as
neuropraxia, compartment syndrome and
rhabdomyolysis
Long-term:
Restricture rate after excision and primary
anastomosis is 10% at 10 years
Recurrence rate after graft or flap reconstrution are
approximately 20%
Cont, Complications
it is not uncommon for patient to report erectile
dysfunction after urethroplasty but recovery generally
occure by 6 month
Conclusion
Stricture of anterior urethra is typically present with
obstructive voiding symptoms
And more frequently associated with iatrogenic
trauma. Retrograde urethrography is the most useful
technique for diagnosis the location of the stricture.
Minimally invasive option such as dilation or
urethrotomy should be limited to short strictures
within bulbar urethra. Urethroplasty with excision and
primary anastomosis has the best success rates and
should be performed when possible. For strictures
that are too long for primary anastomosis
urethroplasty may be performed using grafts or flaps.

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Management of anterior urethral stricture by AUA 2014

  • 1. Management of Anterior urethral strictures AUA update series 2014 Summarized By Mohammed T. Doukhi MD, TechnologyJordan university of Science &
  • 2. outlines ◦ Introdution ◦ Epidemiology and etiology ◦ Diagnosis ◦ Treatment ◦ Complication ◦ Conclusion
  • 3. introduction Definition : It is narrowing of the anterior urethral that impedes flow and implies some degree of spongiofibrosis is called stricture
  • 4. Epidemilogy and etiology Common in men Older than 65 years old Most common is idiopathic 2nd most common is iatrogenic Ex. Cath,cystoscopy,TURP. lichen sclerosus (PXO)
  • 5. Diagnosis  Urethral stricture typically present with obstructive voiding symptoms Such as  Weak stream  Incomplete voiding  Cystitis  Bladder stone Hydronephrosis and renal failure (rare)  Inability to pass catheter in a patient otherwise asymptomatic
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12. Treatment :Urethral dilation Using balloon dilator after placement of guidewire under direct visualization to minimize the risk of creating a false passage or rectal injury Internal urethrotomy: Using a cold-knife incision at 12 o’clock position Foley catheter is left in place for 3 to 5 days
  • 13. Cont, Treatment Many believe that urethrotomy is more effective than dilator, randomized clinical trial of dilation vs. urethrotomy revealed NO long-term difference in outcome. Alternative technique such as resection the scar or use of laser have not provide increase efficacy Disadvantage of dilator and urethrotomy : No benefit if Stricture larger than 1 cm Stricture in penile urethra
  • 16. Cont, Treatment Intraurethral stents : Have been used to treat strictures. Designed for incorporation into urethral mucosa which appear to work best for short bulbar stricture. Stent migration and re-stricture were reported following insertion leading to more difficult urethroplasty is no longer available in the U.S.A®The Urolume
  • 17.
  • 18.
  • 19. Cont, Treatmet :Urothroplasty Based in the location and caliber of the stricture, urethroplasty can be performed either by excision of the stricure with reanastomosis, or with graft or flap Stricture within the penile urethra are rarely excised because shortening the urethra may lead to penile curvature.
  • 20.
  • 21. Complications Urethral dilation may lead to hematuria, false passage and, rarely bladder perforation and rectal injury Urethrotomy may result in hematuria and false passage. Epididymitis, prostatitis, penile curvature and glans necrosis have also been reported Immediate complication after urethroplasty are uncommon but include infection bleeding and thromboembolism
  • 22. Cont, Complications If urethroplasty is performed with the patient in high lithotomy position, surgery for longer than 5 hours has been associated with complications such as neuropraxia, compartment syndrome and rhabdomyolysis Long-term: Restricture rate after excision and primary anastomosis is 10% at 10 years Recurrence rate after graft or flap reconstrution are approximately 20%
  • 23. Cont, Complications it is not uncommon for patient to report erectile dysfunction after urethroplasty but recovery generally occure by 6 month
  • 24. Conclusion Stricture of anterior urethra is typically present with obstructive voiding symptoms And more frequently associated with iatrogenic trauma. Retrograde urethrography is the most useful technique for diagnosis the location of the stricture. Minimally invasive option such as dilation or urethrotomy should be limited to short strictures within bulbar urethra. Urethroplasty with excision and primary anastomosis has the best success rates and should be performed when possible. For strictures that are too long for primary anastomosis urethroplasty may be performed using grafts or flaps.