3. DEFINITION
Stem cells of a particular
tissue are defined as undifferentiated cells,are
capable of proliferation &
are able to self maintain
the population .
5. TYPES
1.Embryonic stem cell-
MULTIPOTENT :
- cell can give rise to multiple
cell type.
PLURIPOTENT :
-able to give rise to derivatives
of 3 germ layer.
TOTIPOTENT :
-able to give rise to entire
organism.
2.Adult stem cell-
UNIPOTENT :
-can produce only one type
6. Microscopic view of colonies
(rounded, dense masses of
cells) of human embryonic stem
cells in biologist James
Thomson's research lab
.
Embryonic stem cells can be
grown in culture dishes. A
pinkish solution provides the
sugars and other compounds
the cells need to grow.
7. TYPES-(Base upon the source
of the origin)
1.Haematopoietic stem cellsBone marrow
2.Mesenchymal/Marrow stromal cellsBone marrow , Culture into Osteoblasts
3.Neural stem cells-
Neurons ,Astrocytes ,Oligodendrocytes
8. THERAPEUTIC APPLICATION OF
STEM CELLS
Cell replacement therapy.
- Myocardial infarction, Parkinson’s disease
Production of heart muscle cells.
- Heart attack
Treatment of diabetes.
- Type-1 Diabetes
Skin replacement therapy.
- During injury
Tissue engineering application.
- Injured organs like liver, kidney, eyes, heart & parts
of the brain .
9.
10. FUTURE PERSPECTIVES
Skin replacement therapy are need further
exploration and extensive investigation,
experimental confirmation and clinical trials.
Before they will be made available as an ideal cell
substitute for the treatment of a number of
degenerative disorder.
ES based cell replacement therapy will
revolutionize medicine in the near future.