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STEM CELL
CONTENTS







Definition
Properties
Types of stem cell:1.Embryonic stem cell
2.Adult stem cell
Application of stem cell
Future of stem cell
DEFINITION


Stem cells of a particular
tissue are defined as undifferentiated cells,are
capable of proliferation &
are able to self maintain
the population .
GENERAL PROPERTIES
1.Capable of dividing &
renewing themselves.
2.Unspecialized cells.
3.Give rise to specialized cells.
TYPES


1.Embryonic stem cell-

 MULTIPOTENT :

- cell can give rise to multiple
cell type.
 PLURIPOTENT :
-able to give rise to derivatives
of 3 germ layer.
 TOTIPOTENT :
-able to give rise to entire
organism.



2.Adult stem cell-

 UNIPOTENT :

-can produce only one type
Microscopic view of colonies
(rounded, dense masses of
cells) of human embryonic stem
cells in biologist James
Thomson's research lab
.

Embryonic stem cells can be
grown in culture dishes. A
pinkish solution provides the
sugars and other compounds
the cells need to grow.
TYPES-(Base upon the source
of the origin)


1.Haematopoietic stem cellsBone marrow



2.Mesenchymal/Marrow stromal cellsBone marrow , Culture into Osteoblasts



3.Neural stem cells-

Neurons ,Astrocytes ,Oligodendrocytes
THERAPEUTIC APPLICATION OF
STEM CELLS


Cell replacement therapy.
- Myocardial infarction, Parkinson’s disease



Production of heart muscle cells.
- Heart attack



Treatment of diabetes.
- Type-1 Diabetes



Skin replacement therapy.
- During injury



Tissue engineering application.

- Injured organs like liver, kidney, eyes, heart & parts
of the brain .
FUTURE PERSPECTIVES
 Skin replacement therapy are need further

exploration and extensive investigation,
experimental confirmation and clinical trials.

 Before they will be made available as an ideal cell
substitute for the treatment of a number of
degenerative disorder.

 ES based cell replacement therapy will

revolutionize medicine in the near future.
Stem Cells
Stem Cells

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Stem Cells

  • 2. CONTENTS      Definition Properties Types of stem cell:1.Embryonic stem cell 2.Adult stem cell Application of stem cell Future of stem cell
  • 3. DEFINITION  Stem cells of a particular tissue are defined as undifferentiated cells,are capable of proliferation & are able to self maintain the population .
  • 4. GENERAL PROPERTIES 1.Capable of dividing & renewing themselves. 2.Unspecialized cells. 3.Give rise to specialized cells.
  • 5. TYPES  1.Embryonic stem cell-  MULTIPOTENT : - cell can give rise to multiple cell type.  PLURIPOTENT : -able to give rise to derivatives of 3 germ layer.  TOTIPOTENT : -able to give rise to entire organism.  2.Adult stem cell-  UNIPOTENT : -can produce only one type
  • 6. Microscopic view of colonies (rounded, dense masses of cells) of human embryonic stem cells in biologist James Thomson's research lab . Embryonic stem cells can be grown in culture dishes. A pinkish solution provides the sugars and other compounds the cells need to grow.
  • 7. TYPES-(Base upon the source of the origin)  1.Haematopoietic stem cellsBone marrow  2.Mesenchymal/Marrow stromal cellsBone marrow , Culture into Osteoblasts  3.Neural stem cells- Neurons ,Astrocytes ,Oligodendrocytes
  • 8. THERAPEUTIC APPLICATION OF STEM CELLS  Cell replacement therapy. - Myocardial infarction, Parkinson’s disease  Production of heart muscle cells. - Heart attack  Treatment of diabetes. - Type-1 Diabetes  Skin replacement therapy. - During injury  Tissue engineering application. - Injured organs like liver, kidney, eyes, heart & parts of the brain .
  • 9.
  • 10. FUTURE PERSPECTIVES  Skin replacement therapy are need further exploration and extensive investigation, experimental confirmation and clinical trials.  Before they will be made available as an ideal cell substitute for the treatment of a number of degenerative disorder.  ES based cell replacement therapy will revolutionize medicine in the near future.