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Blood & Blood Products

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The document discusses various blood components and products used in pediatric transfusion medicine. It describes whole blood and derived blood products like red blood cell concentrates, platelet concentrates, granulocyte concentrates and plasma components. It provides guidelines for transfusing these products in neonates and children based on hemoglobin levels and clinical conditions. It also discusses potential adverse effects of transfusions and their management.

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Blood & Blood Products S.Laxiny Medical Student FHCS EUSL
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transfusion practice in Paediatrics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Blood volume ,[object Object],[object Object],[object Object],[object Object],[object Object]
Hemoglobin concentration in children ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Amount to be transfused must br carefully calculated,
 
Whole Blood (WB)
Whole Blood (WB) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Whole Blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Fresh Whole Blood Packed Red Cells Light spin, 22 o C(within 8 hrs) Platelet Rich Plasma Platelet Concentrate Fresh Plasma Store at 22 o C Freeze(FFP) Heavy spin,22 o C
Preparation of blood components from whole Blood
Whole Blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Whole Blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Whole Blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Fresh Blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Blood Products ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Plasma Derivatives Plasma Components Cellular Components Blood
Red Cell Concentrates
Red Cell Concentrates ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Red Cell Concentrates ,[object Object],[object Object],[object Object],[object Object]
Guidelines for Paediatric red cell transfusions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Guidelines for Paediatric red cell transfusions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Red Cell Concentrates ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Red Cell Concentrates ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Red Cell Concentrates ,[object Object],[object Object],[object Object],[object Object],[object Object]
Sickle cell disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Red Cell Concentrates ,[object Object],[object Object],[object Object],[object Object],[object Object]
Leucoreduced Red Blood Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Leucoreduced Red Blood Cells ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Leucodepleted Red Blood Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Washed Red Blood Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Washed Red Blood Cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ABO group selection for RBC Transfusion Recipient ABO Group Component ABO Group 1 st Choice 2 nd Choice 3 rd Choice 4thChoice A A O None None B B O None None AB AB A B O O O None None None Oh (Bombay Group) Oh None None None
 
Platelets Concentrate ,[object Object],[object Object],[object Object]
Platelets Concentrate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Platelets Concentrate ,[object Object],[object Object],[object Object],[object Object],[object Object]
Platelets Concentrate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Platelets Concentrate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Platelets Concentrate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Platelets Concentrate ,[object Object],[object Object],[object Object],[object Object]
ABO group selection for Platelet Transfusion Recipient ABO Component ABO 1 st Choice 2 nd Choice 3 rd Choice 4thChoice A A AB B O B B AB A O AB AB A B O O O A B AB
 
Granulocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Granulocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Granulocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Irradiated blood products ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Blood warming ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Blood Donation Emblem Blood Donation Emblem
Plasma components ,[object Object],[object Object],[object Object],[object Object]
Fresh frozen plasma
Fresh frozen plasma ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
FFP ,[object Object],[object Object],[object Object],[object Object],[object Object]
Thaw at 4 o C & heavy spin Fresh Frozen Plasma Cryoprecipitate -Refrozen within 1 hr -Store at < - 18 o C Cryoremoved Plasma Freeze -80 o C immediately Stored at < -18 o C
Cryoprecipitate (CRYO) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Cryoprecipitate (CRYO) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cryopoor Plasma / Cryosupernatant ,[object Object],[object Object],[object Object],[object Object],[object Object]
Stored plasma ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ABO group selection for Plasma/FFP Transfusion Recipient ABO Component ABO 1 st Choice 2 nd Choice 3 rd Choice 4thChoice A A AB None None B B AB None None AB AB None None None O O AB A B
World Blood Donor Day-June 14th
Plasma derivatives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Plasma derivatives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Plasma derivatives ,[object Object],[object Object],[object Object],[object Object],[object Object]
Plasma derivatives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Plasma derivatives ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Adverse reactions of Blood Transfusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acute Transfusion Reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acute reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Delayed adverse reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Delayed adverse reaction ,[object Object],[object Object],[object Object]
Acute Haemolytic transfusion reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acute Haemolytic transfusion reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acute Haemolytic transfusion reaction ,[object Object],[object Object],[object Object],[object Object],[object Object]
Acute Haemolytic transfusion reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acute Haemolytic transfusion reaction ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Delayed Haemolytic transfusion reaction ,[object Object],[object Object],[object Object],[object Object]
Delayed Haemolytic transfusion reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Delayed Haemolytic transfusion reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Febrile Non Haemolytic Transfusion Reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Febrile Non Haemolytic Transfusion Reaction ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Transfusion tranmissible infections ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transfusion tranmissible infections ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transfusion tranmissible infections ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transfusion tranmissible infections ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transfusion tranmissible infections ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transfusion tranmissible infections ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Transfusion associated graft versus host disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Skin manifestation of GVHD Generalized swelling, erythroderma and bullous formation
Transfuion associated graft versus host disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transfusion-Related Acute Lung Injury (TRALI) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Transfusion-Related Acute Lung Injury (TRALI) ,[object Object],[object Object],a b
TRALI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Post transfusion purpura ,[object Object],[object Object],[object Object],[object Object],[object Object]
Post transfusion purpura ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Allergic urticarial reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Allergic urticarial reaction ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Anaphylactic reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Anaphylactic reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Iron overload ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Guidelines for Clinical transfusion practices ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Guidelines for Clinical transfusion practices ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Guidelines for Clinical transfusion practices ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Don’ts for Blood Transfusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Thank You

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Blood & Blood Products

  • 1. Blood & Blood Products S.Laxiny Medical Student FHCS EUSL
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  • 11. Fresh Whole Blood Packed Red Cells Light spin, 22 o C(within 8 hrs) Platelet Rich Plasma Platelet Concentrate Fresh Plasma Store at 22 o C Freeze(FFP) Heavy spin,22 o C
  • 12. Preparation of blood components from whole Blood
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  • 35. ABO group selection for RBC Transfusion Recipient ABO Group Component ABO Group 1 st Choice 2 nd Choice 3 rd Choice 4thChoice A A O None None B B O None None AB AB A B O O O None None None Oh (Bombay Group) Oh None None None
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  • 44. ABO group selection for Platelet Transfusion Recipient ABO Component ABO 1 st Choice 2 nd Choice 3 rd Choice 4thChoice A A AB B O B B AB A O AB AB A B O O O A B AB
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  • 51. Blood Donation Emblem Blood Donation Emblem
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  • 56. Thaw at 4 o C & heavy spin Fresh Frozen Plasma Cryoprecipitate -Refrozen within 1 hr -Store at < - 18 o C Cryoremoved Plasma Freeze -80 o C immediately Stored at < -18 o C
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  • 61. ABO group selection for Plasma/FFP Transfusion Recipient ABO Component ABO 1 st Choice 2 nd Choice 3 rd Choice 4thChoice A A AB None None B B AB None None AB AB None None None O O AB A B
  • 62. World Blood Donor Day-June 14th
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