Feature-aligned N-BEATS with Sinkhorn divergence (ICLR '24)
Presentation on Mitochondria
1. GUIDED BY: PRESENTED BY:
DR. K. K. PANIGRAHI SMRUTI RANJAN DANDPAT
ASST. PROF. PBG Admmission.No:10c/15
2. MITOCHONDRIA:
It is a rod shaped cytoplasmic organelle, also called
as “power house of cell”.
Mitochondria means: mitos = thread + chondrion =
granule
Discovered by Kolliker in 1880.
Altmann called them "bioblasts“in 1890.
The term "mitochondria" was coined by Carl Benda
3. The length of mitochondria is 3-10 micrometre and
diameter is 0.5-1.0 micrometre.
Under light microscope, it appear as rod shaped
,filamentous or granular structure in majority of cell.
The average number of mitochondria in a cell varies
from 200-800.
In case of some protozoa the number may vary upto
4. STRUCTURE OF MITOCHONDRIA:
• It contain about-
Protein = 65-70%
lipid = 25-30%
RNA = 1%
DNA = Less than 1%
There are 3 distinct parts to a mitochondrion. They are:
Membrane
Cristae
matrix
5. (A) MEMBRANE:
It consist of-
1. Outer mitochondrial membrane: encloses the entire
organelle.
60 to 75 angstroms (Å) thick.
It contains large numbers of integral membrane protein called
Porins.
2.Intermembrane space: It is the space between the outer
membrane and the inner membrane.
This space is about 40-47 Å.
It is also known as perimitochondrial space.
6. 3.Inner mitochondrial membrane:
The inner membrane is around 1/5 of the total protein in a
mitochondrion.
The inner membrane has 75% protein and 25% lipid.
7.
8. (B) CRISTAE:
The inner mitochondrial membrane has a series of inside
folding which are known as cristae.
It expand the surface area of the inner mitochondrial
membrane, enhancing its ability to produce ATP.
One recent mathematical modeling study has suggested that
the optical properties of the cristae in filamentous
mitochondria may affect propagation of light within the tissue
9. Cross-sectional image of cristae in
rat liver mitochondrion to
demonstrate the likely 3D structure
and relationship to the inner
membrane
10. (C) MATRIX:
The matrix is the space enclosed by the inner membrane.
It is important in the production of ATP.
It contains a highly concentrated mixture of hundreds of
enzymes.
Each mitochondria has the several number of circular DNA
which are present in the matrix or attached to the surface of
the Inner membrane of the mitochondria.
The enzyme associated with Kreb’s cycle are present in
11. ORIGIN OF MITOCHONDRIA:
There are 2 main views about the origin:
1st one is mitochondria has the self replicating property i.e.
the new mitochondria are formed from the fission of the pre-
existing mitochondria.
2nd view is, they originate from the nuclear envelope.
12. FUNCTIONS OF MITOCHONDRIA:
It is the site of cell respiration.
The oxidation of carbohydrate, lipid and protein occurs in
mitochondria.
It supply energy for various process of cell in the form of ATP.
It contain some amount of DNA , so is associated with the
cytoplasmic inheritance.
13. REFERENCE:
Dr. Kaushik Kumar Panigrahi (Asst. Professor Plant Breeding
And Genetics)
Fundamentals of genetics: By B.D. Singh
Wikipedia(https://en.wikipedia.org/wiki/mitochondrion)