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causes of oral malodor
        (intrinsic)
    Amin Abusallamah
Introduction
• Intrinsic causes of bad breath are oral and
  systemic in origin. In general, roughly 10
  percent of these cases are of systemic origin;
  approximately 90 percent of the cases are of
  intraoral origin.
Cont…
• the most important source of oral malodor is
  the microbial deposits on the tongue.
Oral causes
• the dorsal posterior surface of the tongue as
  the primary contributor to bad breath
Cont…
• There is some controversy over the role
  of periodontal diseases in causing bad breath.

• Plaque from the anaerobic
  bacteria growing (subgingival)
  have a foul smell to produce a
  very intense bad breath
Cont…
• Respiratory tract infiction
  that communication with
  oral
  cavity, tonsillitis, post-nasal
  drip (caused by nasal
  infections, sinusitis or nasal
  polyps)
Systemic diseases
• Carcinomas of the upper respiratory
  tract, including the oropharynx, produce
  normal or branched organic acids, while lung
  carcinomas can produce acetone and
  methylethylketone that lead to bad breath.
Cont…
• Liver disease can produce a variety of
  aromatic compounds, such as H2S, aliphatic
  acids, CH3SH, ethanethiol and (CH3)2S.
  Trimethylaminuria is a rare.
Cont…
• metabolic disease with symptoms of
  dysgeusia (perversion of the sense of taste)
  dysosmia (defect or impairment of the sense
  of smell), which are due to excess production
  of trimethylamine (fish odor)
Cont…
• Uremia that is caused by kidney failure also
  produces (CH3)3N along with dimethylamine.
Cont…
• uncontrolled diabetes mellitus can emit
  ketonic breath, which is caused by a metabolic
  disturbance leading to the production of
  acetones and other ketones.
•   Attia EL, Marshall KG. Halitosis. Can Med Assoc J
                1982;126:1281–5.[Abstract]

            •   Rosenberg M. Bad breath: diagnosis and
                treatment. Univ Toronto Dent J 1990;3(2):7–11.

            •   Stamou, E; Kozlovsky, A; Rosenberg, M (2005).
                "Association between oral malodour and
                periodontal disease-related parameters in a
                population of 71 Israelis".

            •   Rosenberg M. Clinical assessment of bad breath:
                current concepts. JADA 1996;127:475 82.
                [Abstract]

            •   Preti G, Lawley HJ, Hormann CA, et al. Non-oral
                and oral aspects of oral malodor. In: Bad breath:
                Research perspectives. Tel Aviv, Israel: Ramot, Tel
                Aviv University; 1995:149–73.

            •   Rosenberg M, Kozlovsky A, Gelernter I, et al.
                Self-estimation of oral malodor. J Dent Res
Reverence       1995;74:1577–82.

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Causes of oral bad odor intrinsic

  • 1. causes of oral malodor (intrinsic) Amin Abusallamah
  • 2. Introduction • Intrinsic causes of bad breath are oral and systemic in origin. In general, roughly 10 percent of these cases are of systemic origin; approximately 90 percent of the cases are of intraoral origin.
  • 3. Cont… • the most important source of oral malodor is the microbial deposits on the tongue.
  • 4. Oral causes • the dorsal posterior surface of the tongue as the primary contributor to bad breath
  • 5. Cont… • There is some controversy over the role of periodontal diseases in causing bad breath. • Plaque from the anaerobic bacteria growing (subgingival) have a foul smell to produce a very intense bad breath
  • 6. Cont… • Respiratory tract infiction that communication with oral cavity, tonsillitis, post-nasal drip (caused by nasal infections, sinusitis or nasal polyps)
  • 7. Systemic diseases • Carcinomas of the upper respiratory tract, including the oropharynx, produce normal or branched organic acids, while lung carcinomas can produce acetone and methylethylketone that lead to bad breath.
  • 8. Cont… • Liver disease can produce a variety of aromatic compounds, such as H2S, aliphatic acids, CH3SH, ethanethiol and (CH3)2S. Trimethylaminuria is a rare.
  • 9. Cont… • metabolic disease with symptoms of dysgeusia (perversion of the sense of taste) dysosmia (defect or impairment of the sense of smell), which are due to excess production of trimethylamine (fish odor)
  • 10. Cont… • Uremia that is caused by kidney failure also produces (CH3)3N along with dimethylamine.
  • 11. Cont… • uncontrolled diabetes mellitus can emit ketonic breath, which is caused by a metabolic disturbance leading to the production of acetones and other ketones.
  • 12. Attia EL, Marshall KG. Halitosis. Can Med Assoc J 1982;126:1281–5.[Abstract] • Rosenberg M. Bad breath: diagnosis and treatment. Univ Toronto Dent J 1990;3(2):7–11. • Stamou, E; Kozlovsky, A; Rosenberg, M (2005). "Association between oral malodour and periodontal disease-related parameters in a population of 71 Israelis". • Rosenberg M. Clinical assessment of bad breath: current concepts. JADA 1996;127:475 82. [Abstract] • Preti G, Lawley HJ, Hormann CA, et al. Non-oral and oral aspects of oral malodor. In: Bad breath: Research perspectives. Tel Aviv, Israel: Ramot, Tel Aviv University; 1995:149–73. • Rosenberg M, Kozlovsky A, Gelernter I, et al. Self-estimation of oral malodor. J Dent Res Reverence 1995;74:1577–82.