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Carpal Tunnel Syndrome


Gershon Zinger MD MS
Hadassah Medical Organization
Jerusalem, Israel
Gershon Zinger MD MS

   Grad School      MIT – mechanical eng
   Medical School   UCLA

   Residency        USC – orthopedic surgery
   Fellowship       UCLA – hand & micro
   Work             Private practice Denver, Colorado

   Current          Hadassah Medical Organization
                     Jerusalem, Israel
Definition
   Carpal comes from the Greek word Karpos –
    means wrist !

   Carpal tunnel syndrome means wrist tunnel
    syndrome

   Syndrome – “A set of symptoms which occur
    together” (from Dorland’s Medical Dictionary)
    (AKA – we don’t really understand it !)
Anatomy
   Wrist tunnel formed by
    bone on bottom and
    ligament on top
   There are 9 tendons
    and one nerve in the
    tunnel
   Analogous to 4 lanes
    of traffic going to 2
    lanes then back to 4 !
Who Gets CTS
   Women more often affected (ratio 3:1)
   Historically more common in retired people
   Associated with repetitive activity
   Can be associated with medical diseases
       Diabetes
       Rheumatoid Arthritis
       Thyroid Disease
Diagnosis of CTS
   History
   Physical Exam
   Nerve Conduction
    Study/EMG
Nerve Exam
   Sensory
   Motor
   Irritability
Nerve Exam - Sensory
    Pattern peripheral or radicular
   Check for altered
    sensation, numbness on
    palmar and dorsal sides
   Middle finger is median n.
   Small finger is ulnar n.
   First dorsal webspace is
    radial nerve innervated
Median Nerve
   The median nerve
    provides feeling to the
    thumb, index, middle
    and part of the ring
    fingers
   Sometimes people
    complain of numbness
    in the little finger that
    may or may not be
    CTS
Nerve Exam
    Sensory
   Numbness over first
    dorsal web space may
    indicate cervical origin
   Numbness glove-
    stocking may indicate
    general neuropathy
   Numbness in non
    anatomic distribution
    may indicate trigger
    points
Nerve Exam
    Sensory
   2 point discrimination
    is an objective test of
    sensibility
       Use large, not small
        paper clip
       As points get closer
        together, it feels like
        one instead of two
       6 mm or less is normal
Nerve Exam
    Motor – Carpal Tunnel
   Look for atrophy of
    thenar muscles
       May be secondary to
        thumb arthritis
   Test strength for
    opposition (median)
Nerve Exam
    Irritability - Carpal Tunnel
                                 Local Compression
Phalen Test (up to 60 seconds)




                                   Tinel’s Sign
Other sources of nerve irritation
    Cervical
   Cervical testing
       Reproduction of
        symptoms with
        extension+rotation
   Numbness that
    extends to shoulder
    level very suspicious
    for proximal origin
Double-Crush Phenomenon
   A compression point
    at one location may
    lower the threshold at
    another location
Other sources of nerve irritation
Thoracic Outlet Syndrome
                   90 degree abduction-external
                   rotation test (AER) – neither
                   too far forward nor too far back
Other sources of nerve irritation
    Thoracic Outlet Syndrome
   Examiner’s thumb
    over anterior scalene
    muscle
Other sources of nerve irritation
    Trigger Points
   Palpation of
    parascapular trigger
    points may cause local
    pain but also reproduce
    tingling and numbness
    distal into hand
       Trapezius
       Rhomboid
       Latissimus
       Posterior arm
Nerve Conduction + EMG
   Nerve Conduction              EMG
    Study                             Needles into muscles
       Test speed of signal           looking for defibrillation
        down the nerve
Nerve anatomy
   A nerve carries
    electricity in two
    directions
   Axons in bundles or
    fascicles
   Micro-circulation
    affected by
    pressure
Saltatory Conduction
Node of Ranvier
Seddon Classification
   Neuropraxia
       Interruption in
        conduction
       Nerve elements normal
       Recovery full
       Recovery can take 6-8
        weeks
   Axontmesis
   Neurotmesis
Seddon Classification
   Neuropraxia
   Axontmesis
       Loss of axon continuity
       EMG 2-3 weeks later may
        show denervation and
        fibrillation potentials
       Epineurium preserved
       Axon may regenerate at
        rate of 1mm/day
       Incomplete recovery
       Final result at one year
   Neurotmesis
Seddon Classification
   Neuropraxia
   Axontmesis
   Neurotmesis
       neurotmesis (neuro as in
        never as in fahgedaboutit)
       Complete loss of nerve
        function
       May include loss or
        scarring of all neural
        elements
       Surgery can still help
        w/pain
Remember:
   Nerve is brain tissue – limited ability to
    recover
   Numbness may go away after 1 day,
    months, a year or never !
   Numbness may be permanent if nerve
    already damaged beyond recovery
Treatment of CTS
   JBJS 1980 – Steroid Injection + splint
       Prospective, one year, 50 hands
       Overall, only 22% of hands were sx-free
       In mild category, 40% hand were sx-free
   J of Hand Surg 1994 – Steroid injection + splint
       Prospective, 76 hands, f/up 1 yr, avg age 38 yo, excluded
        DM, thyroid dz, RA, preg and “severe dz”
       Overall only 13% of hands were sx-free
   JAMA 2002 – surgery vs splint
       Prospective, 147 patients, excluded DM
       At 18 months, 90% success surgery group vs 37% for splint
        group
Surgery - CTR
   Under the skin lies
    palmar fascia
   There are muscles on
    both sides – thenar
    and hypothenar
    consisting of 3
    muscles each
Surgery - CTR
   Under fascia lies
    the transverse
    carpal ligament
   This ligament is cut
    and springs apart
   Ligament later
    heals leaving the
    tunnel larger
Open versus endoscopic
   Open theoretically
    safer
   Endoscopic
    theoretically has faster
    recovery
Injuries
   J of Hand Surgery* – May 1999
       Survey of members of ASSH
       Endoscopic – 455 major injuries
       Open – 283 major injuries




    * Palmer & Toivonen
Postoperative
   Nurse visit at about 10
    days for suture
    removal and nerve
    gliding exercise
   Need to avoid heavy
    or repetitive for one
    month then gradual
    return to activities
   Palm may be sore 2-4
    months
Thank You !

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Carpal Tunnel Syndrome

  • 1. Carpal Tunnel Syndrome Gershon Zinger MD MS Hadassah Medical Organization Jerusalem, Israel
  • 2. Gershon Zinger MD MS  Grad School MIT – mechanical eng  Medical School UCLA  Residency USC – orthopedic surgery  Fellowship UCLA – hand & micro  Work Private practice Denver, Colorado  Current Hadassah Medical Organization Jerusalem, Israel
  • 3. Definition  Carpal comes from the Greek word Karpos – means wrist !  Carpal tunnel syndrome means wrist tunnel syndrome  Syndrome – “A set of symptoms which occur together” (from Dorland’s Medical Dictionary) (AKA – we don’t really understand it !)
  • 4. Anatomy  Wrist tunnel formed by bone on bottom and ligament on top  There are 9 tendons and one nerve in the tunnel  Analogous to 4 lanes of traffic going to 2 lanes then back to 4 !
  • 5. Who Gets CTS  Women more often affected (ratio 3:1)  Historically more common in retired people  Associated with repetitive activity  Can be associated with medical diseases  Diabetes  Rheumatoid Arthritis  Thyroid Disease
  • 6. Diagnosis of CTS  History  Physical Exam  Nerve Conduction Study/EMG
  • 7. Nerve Exam  Sensory  Motor  Irritability
  • 8. Nerve Exam - Sensory Pattern peripheral or radicular  Check for altered sensation, numbness on palmar and dorsal sides  Middle finger is median n.  Small finger is ulnar n.  First dorsal webspace is radial nerve innervated
  • 9. Median Nerve  The median nerve provides feeling to the thumb, index, middle and part of the ring fingers  Sometimes people complain of numbness in the little finger that may or may not be CTS
  • 10. Nerve Exam Sensory  Numbness over first dorsal web space may indicate cervical origin  Numbness glove- stocking may indicate general neuropathy  Numbness in non anatomic distribution may indicate trigger points
  • 11. Nerve Exam Sensory  2 point discrimination is an objective test of sensibility  Use large, not small paper clip  As points get closer together, it feels like one instead of two  6 mm or less is normal
  • 12. Nerve Exam Motor – Carpal Tunnel  Look for atrophy of thenar muscles  May be secondary to thumb arthritis  Test strength for opposition (median)
  • 13. Nerve Exam Irritability - Carpal Tunnel Local Compression Phalen Test (up to 60 seconds) Tinel’s Sign
  • 14. Other sources of nerve irritation Cervical  Cervical testing  Reproduction of symptoms with extension+rotation  Numbness that extends to shoulder level very suspicious for proximal origin
  • 15. Double-Crush Phenomenon  A compression point at one location may lower the threshold at another location
  • 16. Other sources of nerve irritation Thoracic Outlet Syndrome 90 degree abduction-external rotation test (AER) – neither too far forward nor too far back
  • 17. Other sources of nerve irritation Thoracic Outlet Syndrome  Examiner’s thumb over anterior scalene muscle
  • 18. Other sources of nerve irritation Trigger Points  Palpation of parascapular trigger points may cause local pain but also reproduce tingling and numbness distal into hand  Trapezius  Rhomboid  Latissimus  Posterior arm
  • 19. Nerve Conduction + EMG  Nerve Conduction  EMG Study  Needles into muscles  Test speed of signal looking for defibrillation down the nerve
  • 20. Nerve anatomy  A nerve carries electricity in two directions  Axons in bundles or fascicles  Micro-circulation affected by pressure
  • 22. Seddon Classification  Neuropraxia  Interruption in conduction  Nerve elements normal  Recovery full  Recovery can take 6-8 weeks  Axontmesis  Neurotmesis
  • 23. Seddon Classification  Neuropraxia  Axontmesis  Loss of axon continuity  EMG 2-3 weeks later may show denervation and fibrillation potentials  Epineurium preserved  Axon may regenerate at rate of 1mm/day  Incomplete recovery  Final result at one year  Neurotmesis
  • 24. Seddon Classification  Neuropraxia  Axontmesis  Neurotmesis  neurotmesis (neuro as in never as in fahgedaboutit)  Complete loss of nerve function  May include loss or scarring of all neural elements  Surgery can still help w/pain
  • 25. Remember:  Nerve is brain tissue – limited ability to recover  Numbness may go away after 1 day, months, a year or never !  Numbness may be permanent if nerve already damaged beyond recovery
  • 26. Treatment of CTS  JBJS 1980 – Steroid Injection + splint  Prospective, one year, 50 hands  Overall, only 22% of hands were sx-free  In mild category, 40% hand were sx-free  J of Hand Surg 1994 – Steroid injection + splint  Prospective, 76 hands, f/up 1 yr, avg age 38 yo, excluded DM, thyroid dz, RA, preg and “severe dz”  Overall only 13% of hands were sx-free  JAMA 2002 – surgery vs splint  Prospective, 147 patients, excluded DM  At 18 months, 90% success surgery group vs 37% for splint group
  • 27. Surgery - CTR  Under the skin lies palmar fascia  There are muscles on both sides – thenar and hypothenar consisting of 3 muscles each
  • 28. Surgery - CTR  Under fascia lies the transverse carpal ligament  This ligament is cut and springs apart  Ligament later heals leaving the tunnel larger
  • 29. Open versus endoscopic  Open theoretically safer  Endoscopic theoretically has faster recovery
  • 30. Injuries  J of Hand Surgery* – May 1999  Survey of members of ASSH  Endoscopic – 455 major injuries  Open – 283 major injuries * Palmer & Toivonen
  • 31. Postoperative  Nurse visit at about 10 days for suture removal and nerve gliding exercise  Need to avoid heavy or repetitive for one month then gradual return to activities  Palm may be sore 2-4 months