A poster presentation by UCSF researcher Mona Luke-Zeitoun and colleagues from Stanford University and University of Pittsburgh.

1. Effec%veness
Of
Individualized
Non-­‐Supervised
Coached
Exercise
Program
In
Children
With
Cys%c
Fibrosis
M
Luke-­‐Zeitoun1,
D
Nielson1,
D
Orenstein3,
J
Desch2,
R
Moss2
University
of
California
San
Francisco1,
Stanford
University2,
University
of
PiPsburgh3
Background
Methods
Results
• The
benefits
of
exercise
in
CF
pa<ents
are
well
• Assessments
included:
maximal
oxygen
uptake
tes<ng
established
(improved
survival,
slower
decline
in
(VO2max),
strength
tes<ng,
ease
of
breathing
pulmonary
func<on,
enhanced
sputum
clearance)
measurements,
skin
fold
measurements
• Supervised,
standardized
exercise
programs
effec<vely
• A
licensed
personal
trainer
coached
the
children
in
the
improve
clinical
status
in
CF
but
show
poor
long-­‐term
exercise
group
to
design
an
individualized
exercise
adherence
program
that
included
weekly
video
conference
sessions
• Individualized
programs,
incorpora<ng
enjoyed
ac<vi<es,
to
assist
in
their
goals,
monitor
progress
and
modify
the
regular
therapist-­‐pa<ent
contact
and
family
support
are
program
as
needed
associated
with
good
long-­‐term
adherence
Objec%ves
• To
examine
the
effects
of
an
individualized
unsupervised
• Exercise
group
showed
over
6
months:
coached
exercise
program
in
children
with
CF
on
lung
• Stabiliza<on
of
lung
func<on
func<on,
aerobic
capacity,
muscle
strength,
ease
of
• Improvement
in
arm/shoulder
strength
(push
ups)
breathing,
long
term
adherence
• Trend
to
improvement
in
leg
and
abdominal
muscle
strength
(wall
sit,
sit
ups)
Methods
Results
• Control
group
showed
over
6
months:
• Decline
in
lung
func<on
• Design
• Trend
to
decline
in
leg
and
abdominal
muscle
• Randomized
controlled
study
strength
• Par<cipants
• Trend
to
improvement
in
arm/shoulder
strength
• 11
children
with
CF
between
9
and
15
years
(6
girls)
• Ease
of
breathing
measurements
remained
unchanged
• 7
pa<ents
in
exercise
group,
4
in
control
group
in
both
groups
• Exercise
group
par<cipated
in
a
6-­‐month
individualized
non-­‐ • 12
month
measurements
are
expected
to
be
supervised
training
exercise
program
completed
in
all
subjects
by
the
end
of
2012
• Control
group
was
asked
not
to
alter
their
ac<vity
levels
• Pa<ents
were
assessed
at
baseline,
a[er
6
months,
and
a[er
12
months
• No
difference
in
baseline
characteris<cs
between
Conclusions
exercise
and
control
group
Testing Testing Testing • Age
• Individualized
non-­‐supervised
coached
exercise
• Lung
func<on
(FEV1)
programs
may
be
effec<ve
in
stabilizing
lung
func<on
• Maximal
oxygen
uptake
(VO2max)
and
improving
physical
fitness
in
children
with
CF
and
0 6 12
mo mo mo • Body
composi<on
(percentage
body
fat)
could
poten<ally
be
used
as
a
method
to
improve
the
Exercise
overall
health
and
well-­‐being
of
these
children
Program
FUNDING:
NIH/NCRR
UCSF-­‐CTSI
Grant
Number
UL1
RR024131
This project was supported by the CTSI- Clinical Research Services -Body Composition/Exercise Core. For more info
visit http://accelerate.ucsf.edu/research/crs