This document discusses the three main types of skeletal muscle fibers: 1) Slow oxidative fibers (SO) are dark red, contain many mitochondria and blood vessels, generate ATP through aerobic respiration, and contract slowly but resist fatigue well. They are suited for endurance activities like marathon running. 2) Fast oxidative-glycolytic fibers (FOG) are also dark red but generate ATP through both aerobic respiration and anaerobic glycolysis. They contract faster than SO fibers but more slowly than FG fibers. They are suited for activities like walking and sprinting. 3) Fast glycolytic fibers (FG) are white, rely primarily on anaerobic glycolysis to generate

1. Types of
Skeletal
Muscle
Fibers
Andrea Audine Padernal Jandongan
Ma. Windee Nonesco Ireneo

2.  Skeletal muscle fibers are not all alike in
composition and function. For example, muscle
fibers vary in their content of myoglobin.
Myoglobin - the red-colored protein
that binds oxygen in musclefibers.

3.  Skeletal muscle fibers that have a high
myoglobin content are termed red muscle fibers
and appear darker (the dark meat in chicken legs
and thighs); those that have a low content of
myoglobin are called white muscle fibers and
appear lighter (the white meat in chicken breasts).

4. Red muscle fibers
also contain more mitochondria and are
supplied by more blood capillaries.

5.  Skeletal muscle fibers also contract and relax
at different speeds, and vary in which metabolic
reactions they use to generate ATP and in how
quickly they fatigue. For example, a fiber is
categorized as either slow or fast depending on
how rapidly the ATPase in its myosin heads
hydrolyzes ATP.

6.  Based on all these structural and
functional characteristics, skeletal muscle
fibers are classified into three main types:
(1) slow oxidative fibers (SO), (2) fast
oxidative–glycolytic fibers (FOG), and (3)
fast glycolytic fibers (FG).

8. Slow Oxidative Fibers
(Type I Fibers) (Slow-Twitch
Fibers)
 Slow oxidative (SO) fibers appear dark red
because they contain large amounts of myoglobin
and many blood capillaries. Because they have
many large mitochondria, SO fibers generate ATP
mainly by aerobic respiration, which is why they
are called oxidative fibers.

9. Aerobic Respiration is the process of
producing cellular energy involving
oxygen. Cells break down food in the
mitochondria in a long, multi-step
process that produces ATP.

10.  These fibers are said to be “slow” because the
ATPase in the myosin heads hydrolyzes ATP
relatively slowly and the contraction cycle proceeds
at a slower pace than in “fast” fibers. As a result, SO
fibers have a slow speed of contraction. Their twitch
contractions last from 100 to 200 msec, and they
take longer to reach peak tension.

11.  However, slow fibers are very resistant to
fatigue and are capable of prolonged, sustained
contractions for many hours. These slow-twitch,
fatigue-resistant fibers are adapted for maintaining
posture and for aerobic, endurance-type activities
such as running a marathon.

13. Fast Oxidative - Glycolytic Fibers
(Type IIa Fibers)
 Fast oxidative - glycolytic (FOG) fibers are
typically the largest fibers. Like slow oxidative fibers,
they contain large amounts of myoglobin and many
blood capillaries. Thus, they also have a dark red
appearance. FOG fibers can generate considerable
ATP by aerobic respiration, which gives them a
moderately high resistance to fatigue.

14.  Because their intracellular glycogen level is high,
they also generate ATP by anaerobic glycolysis.
FOG fibers are “fast” because the ATPase in their
myosin heads hydrolyzes ATP three to five times
faster than the myosin ATPase in SO fibers, which
makes their speed of contraction faster.

15.  Thus, twitches of FOG fibers reach
peak tension more quickly than those of
SO fibers but are briefer in duration-less
than 100 msec. FOG fibers contribute to
activities such as walking and sprinting.

17. Sprinter vs. Marathoner