High frequency oscillatory ventilation (HFOV) is a type of mechanical ventilation that uses a constant distending pressure (mean airway pressure [MAP]) with pressure variations oscillating around the MAP at very high rates (up to 900 cycles per minute). This creates small tidal volumes, often less than the dead space.

1. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

2. •
•
o
o
o
o
o
•
o
o
o
o
o
o
o
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

3. •
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

4. BAROTRAUMA
High peak airway
pressures
Transfer of air
from airway to
interstitial space
Pneumothorax,
pneumomediastinum,
pneumopericardium,
subcutaneous
emphysema
VOLUTRAUMA
Lung over
distension
Diffuse alveolar
damage, damage
to pulmonary
capillary
membrane
Increased permeability
leading to pulmonary
edema
ATELECTRAUMA
Low end-
expiratory
volumes,
qualitative &
quantitative loss
of surfactant
Under recruited
alveoli
Repetitive opening and
collapse of such alveoli
lead to shear stress &
damage
BIOTRAUMA
PPV activates
inflammatory
cascade
Inflammatory
mediators
Local and systemic
effects
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

5. •
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

6. •
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

7. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

8. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

9. 

Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

10. •
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

11. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

12. INJURY
INJURY
CMV
HFOV
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

13. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

14. •
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

15. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

16. •
•
•
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

17. •
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

18. •
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

19. •
•
–
–
–
–
–
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

20. •
•
•
•
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

21. •
•
•
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

22. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

23. •
•
•
•
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

24. •
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

25. •
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

26. •
•
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

27. Δ
•
•
•
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

28. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

29. Δ
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

30. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

31. •
•
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

32. •
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

33. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

34. •
•



Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

35. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

36. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

37. Time X
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

38. Time X
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

39. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

40. •
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

41. •
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

42. •
•
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

43. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

44. •
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

45. •
•
•
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

46. •
•
•
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

47. •
•
•
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

48. •
•
Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

49. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

50. 1. Goldsmith & Karotkin - Assisted Ventilation of Neonate
2. Pediatric & Neonatal Mechanical Ventilation – Praveen Khilnani -
2nd Ed
3. High Frequency Oscillatory Ventilation – Kathleen Ventre & John
Arnold in Pediatric and Neonatal Respiratory Diseases – Springer
Publications
4. High Frequency Oscillatory Ventilation - Presentation by Vinod
Kumar Gupta & Ira Chiefetz, Duke Childrens Hospital, North
Carolina
5. HFOV – Anesthesia Tutorial of The Week 261 by Sarah Jarvis et al.
6. Sensormedics 3100A Operator Manual – Viasys Health Care
7. HFOV Basics & Practial Applications - Drager Babylog 8000
Manual – Rainer Stachow
8. HFOV – Presentation by Dr Nalinikanth Panigrahy, Rainbow
Hospitals Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati

51. Dr Naveen Kumar Cheri
S.V. Medical College, Tirupati