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Hadoop for Genomics ,[object Object],Spiral Genetics, Inc.
[object Object],[object Object],[object Object],Session Agenda
[object Object],[object Object],[object Object],[object Object],Genomics Source: Nature Publishing Group
[object Object],[object Object],[object Object],[object Object],Full Human Genome DNA Sequencing ,[object Object],[object Object],[object Object],[object Object],Source: AAAS
[object Object],[object Object],[object Object],DNA 101 Source: BBC Science & Technology
[object Object],[object Object],[object Object],DNA 101, continued Computer Analogy: 46 files, chr1-a.dna, chr1-b.dna … chr22-a.dna, chr22-b.dna Diff of chr1-a.dna and chr1-b.dna shows only minor changes Source: NIH Genetics Home Reference
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],DNA 101, continued
[object Object],[object Object],[object Object],[object Object],[object Object],Whole Genome Sequencing ,[object Object],[object Object],Source: Illumina, Inc.
Dropping costs - a problem! ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],The problem, continued
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],The solution, a genomics platform
[object Object],[object Object],[object Object],[object Object],[object Object],Why Hadoop
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Algorithms - Mapping to MapReduce
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Existing use of Hadoop in Genomics
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Alignment to reference based assembly
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Step 1, Alignment (seed based)
[object Object],[object Object],[object Object],[object Object],Step 2, Consensus Calling
Questions? ,[object Object],[object Object]

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