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Whitney R Harris
   Briefly explain the three types of drugs
    discussed
    ◦ Antibiotics
    ◦ Bronchodilator
    ◦ Corticosteroid
   Identify the common respiratory condition(s)
    the drugs are used to treat
   Knowledge of the common side effects
   Basic understanding of the drug physiology
    (function)
   What it is…                     What it treats…
    ◦ A chemical agent used          ◦ Kills bacteria that
      to disrupt the                   causes respiratory
      metabolic process of             infection
      pathogenic(disease             ◦ Common bacterial
      causing)                         respiratory infections
      microorganisms,                  antibiotics treat
      namely bacteria                  include:
    ◦ Common antibiotics               Tuberculosis-bacterial
      amoxicillin, penicillin          infection of the lungs
                                       Pneumonia-Inflammatory
                                        condition of the lungs
                                        that can caused by
                                        bacteria
   How it works…                        DISRUPTS CELL MEMBRANE
                                          PERMEABILITY-The
    ◦ Antibiotics generally work          antibiotic clings to the
      in 4 ways                           bacterial cell wall causing
      INHIBITS CELL WALL                 the cell’s contents to leak
       SYNTHESIS –Disrupts the            out
       creation of the bacterial cell    STOPS METABOLIC
       wall, causing weakness and         SYNTHESIS-Blocks bacterial
       cell death.                        cell metabolism, so the cell
      INHIBITS PROTEIN                   cannot reproduce
       SYNTHESIS-the antibiotic          Antibiotics are primarily
       deprives protein (RNA/DNA)         administered orally (by
       of an essential enzyme,            mouth)
       causing the bacteria to stop
                                        •Common side effects:
       replicating (multiplying) or
       communicating with other         Nausea, diarrhea, rashes,
       cells.                           joint pain (allergic
                                        reactions)

                                         Antibiotics-click to watch!
                                              ***Definitions: Synthesis- growth; Permeability-
                                              the degree of difficulty or ease something can
                                              be penetrated
   What it is…                     What it treats…
    ◦ A chemical agent used          ◦ Bronchospasm-An
      to relax muscle spasm            increase in tone
      in the bronchial tubes           (spasm) of the smooth
                                       muscle of the bronchi
    ◦ Most common type of              leading to the
      bronchodilator is called         narrowing of the airway
      Sympathomimetic                  Bronchospasms are
                                        primarily caused by
                                        allergies, infection,
    ◦ Common                            exercise or stress.
      Sympathomimetic                ◦ Asthma-Inflammation
      drugs include;                   of the bronchioles
      albuterol and                    leading to a narrowing
      ephedrine                        of the airway
   How it works…
    ◦ Stimulates Beta-2 receptors
      Drug is taken, and it
      Stimulates Beta- 2 receptors in the lungs, which
      Activate an enzyme that increases cAMP ( a chemical in
       the body)
      And finally cAMP relaxes the bronchial smooth muscle
    o Bronchodilators are usually administered by oral inhalation-
      inhaler
    o Common side effects: nervousness, anxiety, dry mouth,
      hypertension, tachycardia (increased HR)
   What it is…                  What it treats…
    ◦ A chemical agent that       ◦ Commonly used to
      reduces inflammation          treat Upper Respiratory
      and swelling in the           Infections (URI) such
      respiratory tract             as:
                                    Laryngitis-inflammation
    ◦ Cortisone is the most          of the larynx
      common type of                Rhinitis-inflammation of
                                     the nasal mucosa
      corticosteroid                 (Flonase –nasal spray)
                                    Asthma
   How it works…                              Common side effects: water
    ◦ Corticosteroids are said to:             retention, delayed wound
       Reduce the inflammation of
        the airway, decreasing                 healing, headache
        sensitivity.
       Reduce the release of body
        chemicals from certain
        inflammatory cells, such as;
        prostaglandins.
            Prostaglandins play a major
             role in regulating
             inflammatory states of the
             body
       Increase the effect of
        bronchodilators
        (corticosteroids and
        bronchodilators are often
        coupled medications in
        inhalers).
       Corticosteroids are usually
                                              Corticosteroid-click to
        taken orally or by inhalation          watch!
Fermgen, B . F . , & F r u c h t , S . S . ( 2 0 0 9 ) Medical terminology :
A living language. New Jersey: Pearson- Prentice Hall .

Prentice, W. E. ( 2 0 0 3 ) Arenheim’s principles of athletic training : A
Compentency based approach. New York: McGraw-Hill.

MacDermott, B.L., & Deglin, J. H. (1994) Understanding Basic
Pharmacology: Practical approaches for effective application.
Philadelphia: F. A. Davis.

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Drug Prescriptions[1]

  • 2. Briefly explain the three types of drugs discussed ◦ Antibiotics ◦ Bronchodilator ◦ Corticosteroid  Identify the common respiratory condition(s) the drugs are used to treat  Knowledge of the common side effects  Basic understanding of the drug physiology (function)
  • 3. What it is…  What it treats… ◦ A chemical agent used ◦ Kills bacteria that to disrupt the causes respiratory metabolic process of infection pathogenic(disease ◦ Common bacterial causing) respiratory infections microorganisms, antibiotics treat namely bacteria include: ◦ Common antibiotics  Tuberculosis-bacterial  amoxicillin, penicillin infection of the lungs  Pneumonia-Inflammatory condition of the lungs that can caused by bacteria
  • 4. How it works…  DISRUPTS CELL MEMBRANE PERMEABILITY-The ◦ Antibiotics generally work antibiotic clings to the in 4 ways bacterial cell wall causing  INHIBITS CELL WALL the cell’s contents to leak SYNTHESIS –Disrupts the out creation of the bacterial cell  STOPS METABOLIC wall, causing weakness and SYNTHESIS-Blocks bacterial cell death. cell metabolism, so the cell  INHIBITS PROTEIN cannot reproduce SYNTHESIS-the antibiotic  Antibiotics are primarily deprives protein (RNA/DNA) administered orally (by of an essential enzyme, mouth) causing the bacteria to stop •Common side effects: replicating (multiplying) or communicating with other Nausea, diarrhea, rashes, cells. joint pain (allergic reactions) Antibiotics-click to watch! ***Definitions: Synthesis- growth; Permeability- the degree of difficulty or ease something can be penetrated
  • 5. What it is…  What it treats… ◦ A chemical agent used ◦ Bronchospasm-An to relax muscle spasm increase in tone in the bronchial tubes (spasm) of the smooth muscle of the bronchi ◦ Most common type of leading to the bronchodilator is called narrowing of the airway Sympathomimetic  Bronchospasms are primarily caused by allergies, infection, ◦ Common exercise or stress. Sympathomimetic ◦ Asthma-Inflammation drugs include; of the bronchioles albuterol and leading to a narrowing ephedrine of the airway
  • 6. How it works… ◦ Stimulates Beta-2 receptors  Drug is taken, and it  Stimulates Beta- 2 receptors in the lungs, which  Activate an enzyme that increases cAMP ( a chemical in the body)  And finally cAMP relaxes the bronchial smooth muscle o Bronchodilators are usually administered by oral inhalation- inhaler o Common side effects: nervousness, anxiety, dry mouth, hypertension, tachycardia (increased HR)
  • 7. What it is…  What it treats… ◦ A chemical agent that ◦ Commonly used to reduces inflammation treat Upper Respiratory and swelling in the Infections (URI) such respiratory tract as:  Laryngitis-inflammation ◦ Cortisone is the most of the larynx common type of  Rhinitis-inflammation of the nasal mucosa corticosteroid (Flonase –nasal spray)  Asthma
  • 8. How it works… Common side effects: water ◦ Corticosteroids are said to: retention, delayed wound  Reduce the inflammation of the airway, decreasing healing, headache sensitivity.  Reduce the release of body chemicals from certain inflammatory cells, such as; prostaglandins.  Prostaglandins play a major role in regulating inflammatory states of the body  Increase the effect of bronchodilators (corticosteroids and bronchodilators are often coupled medications in inhalers).  Corticosteroids are usually  Corticosteroid-click to taken orally or by inhalation watch!
  • 9. Fermgen, B . F . , & F r u c h t , S . S . ( 2 0 0 9 ) Medical terminology : A living language. New Jersey: Pearson- Prentice Hall . Prentice, W. E. ( 2 0 0 3 ) Arenheim’s principles of athletic training : A Compentency based approach. New York: McGraw-Hill. MacDermott, B.L., & Deglin, J. H. (1994) Understanding Basic Pharmacology: Practical approaches for effective application. Philadelphia: F. A. Davis.