2. Briefly explain the three types of drugs
discussed
◦ Antibiotics
◦ Bronchodilator
◦ Corticosteroid
Identify the common respiratory condition(s)
the drugs are used to treat
Knowledge of the common side effects
Basic understanding of the drug physiology
(function)
3. What it is… What it treats…
◦ A chemical agent used ◦ Kills bacteria that
to disrupt the causes respiratory
metabolic process of infection
pathogenic(disease ◦ Common bacterial
causing) respiratory infections
microorganisms, antibiotics treat
namely bacteria include:
◦ Common antibiotics Tuberculosis-bacterial
amoxicillin, penicillin infection of the lungs
Pneumonia-Inflammatory
condition of the lungs
that can caused by
bacteria
4. How it works… DISRUPTS CELL MEMBRANE
PERMEABILITY-The
◦ Antibiotics generally work antibiotic clings to the
in 4 ways bacterial cell wall causing
INHIBITS CELL WALL the cell’s contents to leak
SYNTHESIS –Disrupts the out
creation of the bacterial cell STOPS METABOLIC
wall, causing weakness and SYNTHESIS-Blocks bacterial
cell death. cell metabolism, so the cell
INHIBITS PROTEIN cannot reproduce
SYNTHESIS-the antibiotic Antibiotics are primarily
deprives protein (RNA/DNA) administered orally (by
of an essential enzyme, mouth)
causing the bacteria to stop
•Common side effects:
replicating (multiplying) or
communicating with other Nausea, diarrhea, rashes,
cells. joint pain (allergic
reactions)
Antibiotics-click to watch!
***Definitions: Synthesis- growth; Permeability-
the degree of difficulty or ease something can
be penetrated
5. What it is… What it treats…
◦ A chemical agent used ◦ Bronchospasm-An
to relax muscle spasm increase in tone
in the bronchial tubes (spasm) of the smooth
muscle of the bronchi
◦ Most common type of leading to the
bronchodilator is called narrowing of the airway
Sympathomimetic Bronchospasms are
primarily caused by
allergies, infection,
◦ Common exercise or stress.
Sympathomimetic ◦ Asthma-Inflammation
drugs include; of the bronchioles
albuterol and leading to a narrowing
ephedrine of the airway
6. How it works…
◦ Stimulates Beta-2 receptors
Drug is taken, and it
Stimulates Beta- 2 receptors in the lungs, which
Activate an enzyme that increases cAMP ( a chemical in
the body)
And finally cAMP relaxes the bronchial smooth muscle
o Bronchodilators are usually administered by oral inhalation-
inhaler
o Common side effects: nervousness, anxiety, dry mouth,
hypertension, tachycardia (increased HR)
7. What it is… What it treats…
◦ A chemical agent that ◦ Commonly used to
reduces inflammation treat Upper Respiratory
and swelling in the Infections (URI) such
respiratory tract as:
Laryngitis-inflammation
◦ Cortisone is the most of the larynx
common type of Rhinitis-inflammation of
the nasal mucosa
corticosteroid (Flonase –nasal spray)
Asthma
8. How it works… Common side effects: water
◦ Corticosteroids are said to: retention, delayed wound
Reduce the inflammation of
the airway, decreasing healing, headache
sensitivity.
Reduce the release of body
chemicals from certain
inflammatory cells, such as;
prostaglandins.
Prostaglandins play a major
role in regulating
inflammatory states of the
body
Increase the effect of
bronchodilators
(corticosteroids and
bronchodilators are often
coupled medications in
inhalers).
Corticosteroids are usually
Corticosteroid-click to
taken orally or by inhalation watch!
9. Fermgen, B . F . , & F r u c h t , S . S . ( 2 0 0 9 ) Medical terminology :
A living language. New Jersey: Pearson- Prentice Hall .
Prentice, W. E. ( 2 0 0 3 ) Arenheim’s principles of athletic training : A
Compentency based approach. New York: McGraw-Hill.
MacDermott, B.L., & Deglin, J. H. (1994) Understanding Basic
Pharmacology: Practical approaches for effective application.
Philadelphia: F. A. Davis.