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Dr. Wondwossen M.
WOUNDS
Objectives
 Classification
 Wound healing
o Types
o Phases
o Delayed healing
o Abnormal healing
 Wound care
Introduction
Disruption of tissue integrity,
leading to division of blood
vessels
It is caused by a transfer of any
form of energy into the body.
Classification
1- Closed Vs Open
Closed wounds
Skin Intact / Underlying tissue damaged
e.gs contusion, bruise, hematoma.
Open wounds
-Complete break of the epithelial protective
surface.
e.gs abrasion, laceration, puncture, degloved
wound , bites.
2- Tidy Vs Untidy
Tidy Untidy
- Incised - Crushed
- Clean - Contaminated
- Healthy tissue - Devitalized tissue
- Seldom tissue loss - Often tissue loss
3- Acute Vs Chronic
 Acute wounds
 Wounds that heal in expected period of time
 Eg. Lacerations
 Chronic wounds
- Wound that fails to heal over an extended period of
time
- Caused by inadequate circulation or in which
healing is delayed as a result of vascular compromise
- eg. Ulcers
3- Tetanus Prone Vs Tetanus Non-prone
Tetanus Prone
 wound age >6hrs
 wound depth > 1cm
 presence of devitalized tissue
 contaminated wounds
 Animal bites
Tetanus Non-prone
 wound age <6hrs
 wound depth <1cm
 absence of devitalized tissue
 non contaminated wounds
Classification of Surgical Wounds
 Based on the risk of infection & degree of
contamination
- Clean (Class-I)
- Clean-contaminated (Class-II)
- Contaminated (Class-III)
- Dirty (Class-IV)
1- Clean wounds
 No inflammation
 No break in sterile technique
 Wound primarily closed/Not
drained
 Aero- digestive, genitourinary &
Biliary tract not entered
 Potential infection rate 1%-5%
 Examples
 Thyroidectomy
 Mastectomy
 Lipoma excision
2- Clean-contaminated Wound
 No inflammation/Infection present
 Minor break in sterile technique
 Aerodigestive or genitourinary
tract entered without spillage
 Potential infection rate 8% - 10%
 Examples
 Simple appendectomy
 Prostatectomy
 Cholecystectomy
3- Contaminated Wound
 Traumatic wounds
 Acute inflammation present
 Major break in sterile technique
 Gross spillage/contamination
from respiratory,
gastrointestinal, biliary, or
genitourinary tracts
 Potential infection rate 15% -
20%
 Example
 Traumatic wounds
4- Dirty/Infected Wound
 Organisms present at surgical site
prior to procedure/Existing
infection
 Presence of pus
 Perforation (Gastrointestinal,
biliary, respiratory, genitourinary
tract)
 Potential infection rate 27% - 40%
 Example
 Appendiceal abcess
 Peritonitis
Wound Healing
 A complex mechanism involving cellular & chemical
activity
 Healing Vs Regeneration
• Wound repair is the effort of injured tissues to
restore their normal function and structural integrity
after injury.
• Regeneration is perfect restoration of the
preexisting tissue architecture in the absence of
scar formation.
• In adult humans the accuracy of regeneration is
sacrified for the speed of repair
Types of Clinical Wound Healing
oPrimary Intention
oSecondary Intention
oTertiary Intention (Delayed Primary Closure)
Primary Intention
 For clean wounds
 Wound is sutured/closed
 Healing occurs from side-to-
side
 Healing occurs rapidly with little
inflammation and minimal
scarring
Secondary Intention
 For contaminated/dirty wounds
 Wound is intentionally left open
 Healing occurs from the bottom–
up
 Granulation tissue containing
myofibroblasts forms wound
contraction
 Scar formation is extensive
Tertiary Intention (Delayed Primary Closure)
 For contaminated/dirty
 Wound is left open until
clean for 4-6 days
 Then, wound is closed
 Suturing
 Skin grafting
 Flap
Phases of Wound Healing
Hemostasis & Inflammation
phase
Proliferative phase
Maturation & Remodeling phase
Hemostasis & Inflammation phase
 Begins within minutes of the injury and lasts 3
days
 Hemostasis
 Vasoconstriction
 Fibrin clot formation
 Inflammation manifested by heat, redness,
swelling, pain, loss of function
 Platelets, Neutrophils & Monocytes
 Goals of this phase are
 Arrest bleeding
 Remove dead tissue & foreign bodies
 Stimulate next phase of wound healing
Proliferative phase
 Begins about the 3rd post injury day & continues up to
3wks
 Fibroblasts & Endothelial cells
 Collagen(type-3) & new blood vessels
formation(angiogenesis)
Maturation & Remodeling phase
 Lasts until the wound is completely healed, (may take
up to 1-2 yr)
 Tensile strength increased by interweaving of collagen
fibers
 Conversion of type-3 collagen to Type-1 collagen
 Collagen density increases & formation of new blood
vessels decreases
 Mature scar is formed
Factors affecting wound healing
Local
 Ischemia
 Infection
 Foreign body
 Edema
Systemic
 Age
 Stress
 Ischemia
 Diabetes
 Steroids
 Smoking
 Immunocompromise
 Malnutrition
Abnormal wound healing
 Hypertrophic scar

 Keloid
Wound Management
1- Assessment of wounds
- duration since injury
- identification of possible contamination & Fb.
- extent of wound
- associated neurovascular or tendon injury
- need of tetanus prophylaxis
- identification of risk factors that might affect
healing.
2- Wound preparation
- irrigation helps in:
- to visualize areas of the wound.
- to remove Fb
- foreign body removal
- necrotic tissue debridement
- evacuation of hematoma
- haemostasis
3-Wound Closure
Timing
The choices are:
(1) close at the time of initial
presentation
(2) delay closure until after a period of
healing or wound care, and
(3) to allow the wound to heal on its own.
Methods
The closure methods available include:
(1) primary closure by direct
approximation (2) delayed primary closure,
(3) secondary closure-left to heal on its
own.
(4) skin grafting; and
4- Dressing
maintain a moist clean environment
prevent pressure and mechanical trauma
reduce edema
stimulates repair
comfort and aesthetic appearance
Other adjuncts
 Antibiotics
o Prophylactic
o Therapeutic
 Tetanus Prophylaxis
Special wounds
 Human bites
 Management
o Thorough irrigation with saline or plain water
o Adequate debridement
o Leave wound open
o Broad-spectrum antibiotics
o Tetanus Prophylaxis
o Wound observation
 Dog bites
 Management
o Vigorous irrigation
o Leave wound open
o Tetanus prophylaxis
o Antibiotics
o Post exposure anti rabies prophylaxis (1ml, IM)
on the 1st, 3rd, 7th, 14th and 28th day of bite.
Thank You

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Wound for c i

  • 2. Objectives  Classification  Wound healing o Types o Phases o Delayed healing o Abnormal healing  Wound care
  • 3. Introduction Disruption of tissue integrity, leading to division of blood vessels It is caused by a transfer of any form of energy into the body.
  • 4. Classification 1- Closed Vs Open Closed wounds Skin Intact / Underlying tissue damaged e.gs contusion, bruise, hematoma. Open wounds -Complete break of the epithelial protective surface. e.gs abrasion, laceration, puncture, degloved wound , bites.
  • 5. 2- Tidy Vs Untidy Tidy Untidy - Incised - Crushed - Clean - Contaminated - Healthy tissue - Devitalized tissue - Seldom tissue loss - Often tissue loss
  • 6. 3- Acute Vs Chronic  Acute wounds  Wounds that heal in expected period of time  Eg. Lacerations  Chronic wounds - Wound that fails to heal over an extended period of time - Caused by inadequate circulation or in which healing is delayed as a result of vascular compromise - eg. Ulcers
  • 7. 3- Tetanus Prone Vs Tetanus Non-prone Tetanus Prone  wound age >6hrs  wound depth > 1cm  presence of devitalized tissue  contaminated wounds  Animal bites Tetanus Non-prone  wound age <6hrs  wound depth <1cm  absence of devitalized tissue  non contaminated wounds
  • 8. Classification of Surgical Wounds  Based on the risk of infection & degree of contamination - Clean (Class-I) - Clean-contaminated (Class-II) - Contaminated (Class-III) - Dirty (Class-IV)
  • 9. 1- Clean wounds  No inflammation  No break in sterile technique  Wound primarily closed/Not drained  Aero- digestive, genitourinary & Biliary tract not entered  Potential infection rate 1%-5%  Examples  Thyroidectomy  Mastectomy  Lipoma excision
  • 10. 2- Clean-contaminated Wound  No inflammation/Infection present  Minor break in sterile technique  Aerodigestive or genitourinary tract entered without spillage  Potential infection rate 8% - 10%  Examples  Simple appendectomy  Prostatectomy  Cholecystectomy
  • 11. 3- Contaminated Wound  Traumatic wounds  Acute inflammation present  Major break in sterile technique  Gross spillage/contamination from respiratory, gastrointestinal, biliary, or genitourinary tracts  Potential infection rate 15% - 20%  Example  Traumatic wounds
  • 12. 4- Dirty/Infected Wound  Organisms present at surgical site prior to procedure/Existing infection  Presence of pus  Perforation (Gastrointestinal, biliary, respiratory, genitourinary tract)  Potential infection rate 27% - 40%  Example  Appendiceal abcess  Peritonitis
  • 13. Wound Healing  A complex mechanism involving cellular & chemical activity  Healing Vs Regeneration • Wound repair is the effort of injured tissues to restore their normal function and structural integrity after injury. • Regeneration is perfect restoration of the preexisting tissue architecture in the absence of scar formation. • In adult humans the accuracy of regeneration is sacrified for the speed of repair
  • 14. Types of Clinical Wound Healing oPrimary Intention oSecondary Intention oTertiary Intention (Delayed Primary Closure)
  • 15. Primary Intention  For clean wounds  Wound is sutured/closed  Healing occurs from side-to- side  Healing occurs rapidly with little inflammation and minimal scarring
  • 16. Secondary Intention  For contaminated/dirty wounds  Wound is intentionally left open  Healing occurs from the bottom– up  Granulation tissue containing myofibroblasts forms wound contraction  Scar formation is extensive
  • 17. Tertiary Intention (Delayed Primary Closure)  For contaminated/dirty  Wound is left open until clean for 4-6 days  Then, wound is closed  Suturing  Skin grafting  Flap
  • 18. Phases of Wound Healing Hemostasis & Inflammation phase Proliferative phase Maturation & Remodeling phase
  • 19. Hemostasis & Inflammation phase  Begins within minutes of the injury and lasts 3 days  Hemostasis  Vasoconstriction  Fibrin clot formation  Inflammation manifested by heat, redness, swelling, pain, loss of function  Platelets, Neutrophils & Monocytes  Goals of this phase are  Arrest bleeding  Remove dead tissue & foreign bodies  Stimulate next phase of wound healing
  • 20. Proliferative phase  Begins about the 3rd post injury day & continues up to 3wks  Fibroblasts & Endothelial cells  Collagen(type-3) & new blood vessels formation(angiogenesis)
  • 21. Maturation & Remodeling phase  Lasts until the wound is completely healed, (may take up to 1-2 yr)  Tensile strength increased by interweaving of collagen fibers  Conversion of type-3 collagen to Type-1 collagen  Collagen density increases & formation of new blood vessels decreases  Mature scar is formed
  • 22. Factors affecting wound healing Local  Ischemia  Infection  Foreign body  Edema Systemic  Age  Stress  Ischemia  Diabetes  Steroids  Smoking  Immunocompromise  Malnutrition
  • 23. Abnormal wound healing  Hypertrophic scar   Keloid
  • 24. Wound Management 1- Assessment of wounds - duration since injury - identification of possible contamination & Fb. - extent of wound - associated neurovascular or tendon injury - need of tetanus prophylaxis - identification of risk factors that might affect healing.
  • 25. 2- Wound preparation - irrigation helps in: - to visualize areas of the wound. - to remove Fb - foreign body removal - necrotic tissue debridement - evacuation of hematoma - haemostasis
  • 26. 3-Wound Closure Timing The choices are: (1) close at the time of initial presentation (2) delay closure until after a period of healing or wound care, and (3) to allow the wound to heal on its own. Methods The closure methods available include: (1) primary closure by direct approximation (2) delayed primary closure, (3) secondary closure-left to heal on its own. (4) skin grafting; and
  • 27. 4- Dressing maintain a moist clean environment prevent pressure and mechanical trauma reduce edema stimulates repair comfort and aesthetic appearance
  • 28. Other adjuncts  Antibiotics o Prophylactic o Therapeutic  Tetanus Prophylaxis
  • 29. Special wounds  Human bites  Management o Thorough irrigation with saline or plain water o Adequate debridement o Leave wound open o Broad-spectrum antibiotics o Tetanus Prophylaxis o Wound observation  Dog bites  Management o Vigorous irrigation o Leave wound open o Tetanus prophylaxis o Antibiotics o Post exposure anti rabies prophylaxis (1ml, IM) on the 1st, 3rd, 7th, 14th and 28th day of bite.