Theralase Technologies Inc. (TSXV: TLT) announced that its proprietary Photo Dynamic Compound (PDC) technology has been approved for use in a live animal bladder cancer model by the University Health Network (UHN) Research Ethics Board. This approval expedites the Company’s progress towards commercializing its advanced bladder cancer therapy.

1. Press Release
Theralase Achieves Commercialization Milestone For Its Bladder Cancer Therapy
Toronto, ON -- March 14, 2013 -- Theralase Technologies Inc. (TSXV: TLT) announced that its proprietary
Photo Dynamic Compound (PDC) technology has been approved for use in a live animal bladder cancer
model by the University Health Network (UHN) Research Ethics Board. This approval expedites the
Company’s progress towards commercializing its advanced bladder cancer therapy.
Theralase’s leading proprietary oncology PDC has repeatedly demonstrated that it is:
• toxic to bladder cancer cells when light activated (100% kill rate)
• exceeds potency of FDA approved PDCs
• highly stable ensuring optimal tumour destruction
Theralase will validate its PDC technology in this animal cancer model to support an Investigational New
Drug (IND) application to be filed with the FDA later this year. This IND application will allow Theralase to
commence a Phase 1/2a human clinical trial to prove the safety and efficacy of its PDC technology on a
30 subject population with scheduled completion in 2014. Based on recent pharmaceutical acquisitions
for oncology drugs and market statistics, the estimated value of the PDC upon successful completion of a
FDA Phase 1/2a clinical trial ranges from $84 million to $360 million in upfront payments followed by a
double digit revenue royalty stream. (Source: BIO statistics)
Arkady Mandel MD, PhD, DSc, Chief Scientific Officer of Theralase Technologies Inc. stated, “Protocols
and standard operating procedures are in place to ensure adherence to the highest scientific and ethical
standards. In addition, the program has been fully accredited by the Canadian Council for Animal Care.
This critical research is a vital progressive step that will greatly advance our innovative bladder cancer
therapy.”
Michael Jewett, FRCSC, MD, an eminent urologist and a member of the Department of Surgical Oncology
at UHN’s Princess Margaret Cancer Centre, as well as a member of Theralase’s Medical and Scientific
Advisory Board said, “The elements of Theralase’s PDC development plan are in place and I believe they
will lead to a successful FDA Phase 1/2a human clinical bladder cancer trial to commence early next
year. With a recurrence rate of nearly 80%, bladder cancer is the most expensive cancer to treat on a per
patient basis and raises many issues affecting the quality of life because of its persistence.”
Roger Dumoulin-White, President and CEO of Theralase Inc. stated, “Our leading PDC drug candidate has
been proven to be superior to any currently approved FDA PDC on the market. As we continue to
achieve our critical research milestones, Theralase’s leading PDC provides indisputable proof of its
efficacy in the destruction of cancer in live animal models. Subject to a successful FDA Phase 1/2a
human clinical bladder cancer trial of the PDC technology, Theralase will apply for “breakthrough status”
with the FDA, which if granted, would allow Theralase the unique opportunity of commercializing its
technology without the need for further FDA clinical trials, thus allowing the bladder cancer technology
the most direct route to fulfill an unmet medical need and aid in the destruction of a deadly disease.”

2. Press Release
About Theralase Technologies Inc.:
Theralase Technologies Inc., founded in 1995, designs, develops, manufactures and markets patented,
superpulsed laser technology utilized in biostimulation and biodestruction applications. Theralase
technology is safe and effective in treating pain, inflammation and for tissue regeneration of neural
muscular skeletal conditions and wound healing. Theralase is currently developing patented Photo
Dynamic Compounds (PDCs) that are able to target and destroy cancers, bacteria and viruses when light
activated by Theralase’s proprietary and patented laser technology.
For further information please visit www.theralase.com , regulatory filings may be viewed by visiting
www.sedar.com.
This press release contains forward-looking statements, which reflect the Company's current expectations regarding future events. The forward-looking
statements involve risks and uncertainties. Actual results could differ materially from those projected herein. The Company disclaims any obligation to update
these forward-looking statements.
Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchanges) accepts responsibility
for the adequacy or accuracy of this release.
For More Information:
Roger Dumoulin-White
President & CEO
416-699-5273 ext. 225
rwhite@theralase.com
Kristina Hachey
Chief Financial Officer
416-699-5273 ext. 224
khachey@theralase.com
Arkady Mandel
Chief Scientific Officer
416-699-5273 ext. 242
amandel@theralase.com
Greg Bewsh
Director of Investor Relations
416-699-5273 ext. 258
gbewsh@theralase.com