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[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
STAYING HEALTHY  THROUGHOUT THE LIFECYCLES
A Healthy Beginning: Good Nutrition
LIVING in the MODERN WORLD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CHILDREN’S   HEALTH ,[object Object],[object Object]
EPIGENETICS  ,[object Object]
Our Modern Food Culture
MODERN NUTRITIONAL CRISIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Surgeon General’s Fact Sheet, 2010 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Born to be Big ,[object Object],[object Object]
CDC Report 2010 ,[object Object],[object Object],[object Object]
Impact of maternal diet during pregnancy and breastfeeding on infant metabolic programming .   Eur J Clin Nutr. 2010 Oct 13.  ,[object Object]
British Medical Journal, Nov, 2010 Children who have a high body mass index (BMI) between 9 and 12 years of age are more likely to have high blood pressure, cholesterol and blood insulin levels (all risk factors for developing heart disease) by the time they reach adolescence "Our findings highlight the need to shift the whole childhood population distribution of adiposity downwards and to develop interventions that safely and effectively reduce weight and improve cardiovascular risk factors in overweight/obese children."  A high BMI in childhood linked   to greater heart disease risk in adolescence
OBESOGENS ,[object Object]
OBESOGENS DEFINED ,[object Object],[object Object],[object Object],[object Object]
ENVIRONMENTAL OBESOGENS ,[object Object],[object Object]
Environmental Obesogens: Organotins and Endocrine Disruption via Nuclear Receptor Signaling ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
OBESITY  DEFINED ,[object Object],[object Object],[object Object],[object Object]
globalization of culinary culture  OUR MODERN DIET
F.D.A. Panel to Consider Warnings for Artificial Food Colorings  ,[object Object],[object Object],[object Object]
U.S. Centers for Disease Control and Prevention (CDC) surveyed 73,000 children, they found one in 10 has ADHD -2003.   The Lancet  concluded that a variety of common food dyes, and the preservative sodium benzoate -- found in many soft drinks, fruit juices and salad dressings - cause some children to become measurably more  hyperactive and distractible .   Blue #1 and #2 food coloring  Green #3  Orange B  Red #3 and #40  Yellow #5 and #6  Sodium benzoate, a preservative
INHERITING THE FUTURE ,[object Object]
[object Object],[object Object]
DIET and CANCER ,[object Object],[object Object],[object Object]
NUTRIGENOMICS ,[object Object],[object Object],[object Object],[object Object],[object Object]
MAYAN MARKET
FOOD AS MEDICINE
BACK TO OUR ROOTS
OUR FOOD SUPPLY
80,000 Chemicals  + ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ENVIRONMENTAL EXPOSURES in the FOOD CHAIN  Pesticides ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Children and Cancer ,[object Object],[object Object]
Children’s Health ,[object Object],[object Object]
PRESIDENT’S CANCER PANEL REPORT ,[object Object],[object Object]
CDC Report 2010 ,[object Object],[object Object],[object Object]
Combating Environmental Causes of Cancer Harvard School of Public Health David C. Christiani, M.D., M.P.H. N Engl J Med March 3, 2011; 364:791-793 The knowledge that environmental factors play a role in carcinogenesis dates back centuries. Dr. Percival Pott described scrotal tumors in young chimney sweeps of 18th-century London, demonstrating that cancer could be caused by environmental factors. This discovery led to the passage of public health legislation regarding disease prevention. “ We need. . . a new national cancer-prevention strategy emphasizing primary prevention that redirects both research and policy agendas and sets tangible goals for reducing or eliminating environmental exposures implicated in cancer causation.”
Fourth National Report on Human Exposure to Environmental Chemicals   ,[object Object],[object Object],[object Object]
The first WHO international conference on the primary prevention of cancer through environmental and occupational interventions: A Call to Action  17-18 March 2011 Spain ,[object Object],[object Object]
CRITICAL WINDOWS OF DEVELOPMENT
TOXIC EXPOSURES OVER TIME ,[object Object],[object Object],[object Object]
CONCERNS ,[object Object],[object Object],[object Object]
Exposures throughout Life Cycle ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Time Magazine, circa 1947
PRE NATAL PESTICIDE EXPOSURES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Prenatal exposure  ,[object Object]
Household exposure to pesticides and risk of childhood acute leukaemia ,[object Object],[object Object]
Exposure to professional pest control treatments and the risk of childhood acute lymphoblastic leukemia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Impact of low-level exposure to organophosphates on human reproduction and survival ,[object Object],[object Object],[object Object]
Gene expression profiles following exposure to a developmental neurotoxicant, Aroclor 1254: Pathway analysis for possible mode(s) of action Epidemiological studies indicate that low levels of polychlorinated bisphenyl (PCB) exposure can adversely affect neurocognitive development Toxicology and Applied Pharmacology, Volume231,  Issue 2, 1 September 2008,Pages 179-196 Joyce E. Royland and Prasada Rao S. Kodavanti  
AUTISM RATES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cancer Clusters Reported in U S March 28 th , 2011 ,[object Object],[object Object]
Endocrine Disruptors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PERSONAL CARE PRODUCTS DO YOU KNOW WHAT IS IN  THEM?
[object Object],[object Object]
BISPHENOL A (BPA) ,[object Object]
BPA in Canned Foods
Low levels of BPA raise breast cancer risk in rat offspring. ,[object Object],[object Object],[object Object],[object Object]
BPA in Food Packaging Study   What happens when you try to get BPA out of your diet?   ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Phthalates ,[object Object],[object Object]
Baby Care Products: Possible Sources of Infant Phthalate Exposure ,[object Object],[object Object],[object Object],[object Object],[object Object]
Phthalate  Research Influence of environment on Insulin Sensitivity Latini G, Marcovecchio ML, Del Vecchio A, Gallo F, Bertino E, Chiarelli Environ Int. 2009 Aug;35(6):987-93. Epub 2009 Apr 23. Intereference of Pollutants with PPARS:Endocrine Disruption meets Metabolism . Casals-Casas C, Feige JN, Desvergne B. Int J Obes (2008 Dec;32 Suppl 6:S53-61. 19079281  Perturbed nuclear receptor signaling b y environmental obesogens as emerging factors in the obesity crisis Grün F, Blumberg B. Rev Endocr Metab Disord. 2007 Jun;8(2):161-71. Review.PMID: 17657605 
Challenges for Public Health and Safety ,[object Object],[object Object],[object Object]
PRECAUTIONARY PRINCIPLE   Do  NO HARM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ACRI Guidelines ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
KEY TO GOOD CHILD HEALTH ,[object Object],[object Object],[object Object],[object Object],[object Object]
“ WE DO NOT INHERIT THE EARTH FROM OUR ANCESTORS   WE BORROW IT FROM OUR CHILDREN”   Native American Proverb

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Children's Health

  • 1.
  • 2. STAYING HEALTHY THROUGHOUT THE LIFECYCLES
  • 3. A Healthy Beginning: Good Nutrition
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  • 7. Our Modern Food Culture
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  • 13. British Medical Journal, Nov, 2010 Children who have a high body mass index (BMI) between 9 and 12 years of age are more likely to have high blood pressure, cholesterol and blood insulin levels (all risk factors for developing heart disease) by the time they reach adolescence "Our findings highlight the need to shift the whole childhood population distribution of adiposity downwards and to develop interventions that safely and effectively reduce weight and improve cardiovascular risk factors in overweight/obese children." A high BMI in childhood linked to greater heart disease risk in adolescence
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  • 19. globalization of culinary culture OUR MODERN DIET
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  • 21. U.S. Centers for Disease Control and Prevention (CDC) surveyed 73,000 children, they found one in 10 has ADHD -2003. The Lancet concluded that a variety of common food dyes, and the preservative sodium benzoate -- found in many soft drinks, fruit juices and salad dressings - cause some children to become measurably more hyperactive and distractible . Blue #1 and #2 food coloring Green #3 Orange B Red #3 and #40 Yellow #5 and #6 Sodium benzoate, a preservative
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  • 28. BACK TO OUR ROOTS
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  • 36. Combating Environmental Causes of Cancer Harvard School of Public Health David C. Christiani, M.D., M.P.H. N Engl J Med March 3, 2011; 364:791-793 The knowledge that environmental factors play a role in carcinogenesis dates back centuries. Dr. Percival Pott described scrotal tumors in young chimney sweeps of 18th-century London, demonstrating that cancer could be caused by environmental factors. This discovery led to the passage of public health legislation regarding disease prevention. “ We need. . . a new national cancer-prevention strategy emphasizing primary prevention that redirects both research and policy agendas and sets tangible goals for reducing or eliminating environmental exposures implicated in cancer causation.”
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  • 39. CRITICAL WINDOWS OF DEVELOPMENT
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  • 49. Gene expression profiles following exposure to a developmental neurotoxicant, Aroclor 1254: Pathway analysis for possible mode(s) of action Epidemiological studies indicate that low levels of polychlorinated bisphenyl (PCB) exposure can adversely affect neurocognitive development Toxicology and Applied Pharmacology, Volume231, Issue 2, 1 September 2008,Pages 179-196 Joyce E. Royland and Prasada Rao S. Kodavanti  
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  • 53. PERSONAL CARE PRODUCTS DO YOU KNOW WHAT IS IN THEM?
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  • 56. BPA in Canned Foods
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  • 61. Phthalate Research Influence of environment on Insulin Sensitivity Latini G, Marcovecchio ML, Del Vecchio A, Gallo F, Bertino E, Chiarelli Environ Int. 2009 Aug;35(6):987-93. Epub 2009 Apr 23. Intereference of Pollutants with PPARS:Endocrine Disruption meets Metabolism . Casals-Casas C, Feige JN, Desvergne B. Int J Obes (2008 Dec;32 Suppl 6:S53-61. 19079281  Perturbed nuclear receptor signaling b y environmental obesogens as emerging factors in the obesity crisis Grün F, Blumberg B. Rev Endocr Metab Disord. 2007 Jun;8(2):161-71. Review.PMID: 17657605 
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  • 66. “ WE DO NOT INHERIT THE EARTH FROM OUR ANCESTORS WE BORROW IT FROM OUR CHILDREN” Native American Proverb