CHARACTERIZATION OF GRANULES.

CHARACTERIZATION OF GRANULES & COMPACTS ,[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

CONTENTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

CONTENTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

WHAT ARE GRANULES? ,[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

HOW GRANULES ARE PREPARED? ,[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

NEED FOR GRANULATION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

CHARACTERIZATION OF GRANULES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

2. SURFACE AREA ,[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

Continued….. ,[object Object],[object Object],SVERI's COP,PANDHARPUR.

3. DENSITY ,[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

Continued….. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

GRANULE STRENGTH & FRIABILITY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

FLOW PROPERTIES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

Continued….. ,[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

SVERI's COP,PANDHARPUR. Continued… Fig(1) Fixed height Fig(2) fixed base cone Fig (3) Tilting angle Fig (4) Rotating cylinder

Continued… ,[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

continued… ,[object Object],SVERI's COP,PANDHARPUR.

HOPPER FLOW RATE ,[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

MOISTURE CONTENT ,[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

SAROTORIOUS MA-100 MOISTURE ANALYZER VARIOUS INSTRUMENTS OF IR BALANCES SVERI's COP,PANDHARPUR.

continued… ,[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

PERCENTAGE FINES ( % FINES ) ,[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

EVALUATION OF TABLETS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

GENERAL APPEARANCE ,[object Object],[object Object],SVERI's COP,PANDHARPUR.

WEIGHT VARIATION ,[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

WEIGHT VARIATION TOLERANCES FOR UNCOATED TABLETS USP XX NF- STANDARDS ,[object Object],[object Object],SVERI's COP,PANDHARPUR. Sr. No Average wt. of tablet(mg) Max. % difference allowed 1 130 or Less 10% 2 130-324 7.5% 3 More than 324 5%

DISINTEGRATION TEST ,[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

VARIOUS INSTRUMENTS OF DISINTEGRATION TEST APPARATUS SVERI's COP,PANDHARPUR.

DISSOLUTION TEST ,[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

The rate of drug absorption Acidic drug moiety absorbed high in GI tract Determined by rate of drug dissolution from the tablet. SVERI's COP,PANDHARPUR.

Various instruments of Dissolution test apparatus SVERI's COP,PANDHARPUR.

FRIABILITY ,[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

Various instruments of Roche’s friabilator SVERI's COP,PANDHARPUR.

HARDNESS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

TYPES OF HARDNESS TESTER ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

Monsanto hardness tester Pfizer hardness tester SVERI's COP,PANDHARPUR.

THICKNESS ,[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

VARIOUS INSTRUMENTS OF VERNIER CALIPER SVERI's COP,PANDHARPUR.

REFERENCE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

QUESTIONS ASKED IN PREVIOUS EXAMS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],SVERI's COP,PANDHARPUR.

THANK YOU SVERI's COP,PANDHARPUR.

CHARACTERIZATION OF GRANULES.

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CHARACTERIZATION OF GRANULES.