2. Function of Lower Urinary
Tract
STORAGE of adequate volumes of urine at low
pressure & with no leakage
EMPTYING that is
Voluntary
Efficient
Complete
Low pressure
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3. Anatomy of the Lower Urinary
Tract
Bladder (detrusor)
Stores urine at low pressure
Compresses urine for voiding
Urethra
Conveys urine from bladder to outside world
Sphincter(s) internal & external
Controls urine flow & maintain continence
between voidings
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9. 2.URINARY RETENTION
Urinary retention is inability to empty the
bladder completely during attempts to
void.
CAUSES:-
Prostatic enlargement
Pregnancy
Infection
Neurologic disorders
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10. 3.NEUROGENIC BLADDER
Neurologic bladder is a dysfunction that
results from a lesion of the nervous
system.
CAUSES
Spinal injury
Multiple sclerosis
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Benign Prostatic Hyperplasia
Generalised disease of the
prostate due to hormonal
derangement which leads
to enlargement of the
gland .
12. INCIDENCES
Occurs in 50% of men over 50 and in 80% of
men over 80 have BPH.
Many men with BPH may have mild
symptoms and may never need treatment.
In India total no patients 1,696,347.
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13. BPH Etiologies
Cause not completely understood
Change in hormonal with alterations in the
testosterone/estrogen balance
Induction of prostatic growth factors
Increased stem cells
Accumulation of dihydroxytestosterone.
16. BPH
Pathophysiology
Slow and insidious changes over time
Complex interactions between prostatic urethral
resistance, intravesical pressure, detrussor
functionality, neurologic integrity, and general
physical health.
Initial hypertrophydetrussor decompensation
poor tonediverticula formationincreasing urine
volumehydronephrosisupper tract dysfunction
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Clinical manifestations
Voiding symptoms
decrease in the urinary stream
Dribbling at the end of urination
Hesitancy
Pain or burning during urination
Feeling of incomplete bladder emptying
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Clinical manifestations
Irritative symptoms
urinary frequency
dysuria
bladder pain
nocturia
incontinence
symptoms associated with infection
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Diagnostic Tests
History & Examination
Digital rectal exam (DRE)
Urinalysis
Urine culture
BUN
Prostate specific
antigen (PSA)
Transrectal
ultrasound – biopsy
Uroflometry
24. Watchful Waiting and Behavioral
Modification
“is the preferred management technique in
patients with mild symptoms.
AUA score < 7,
25. Watchful Waiting and Behavioral
Modification
Decrease caffeine, alcohol )diuretic effect(
Avoid taking large amounts of fluid over a short
period of time
Void whenever the urge is present, every 2-3 hours
Maintain normal fluid intake, do not restrict fluid
Avoid bladder irritants to include dairy products,
artificial sweeteners, carbonated beverages
Limit nighttime fluid consumption
BPH symptoms can be variable, intermittent
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Medical Management
Alpha adrenergic receptor blockers
promote smooth muscle relaxation in the prostate
Relaxation of the muscles facilitates urinary flow
Doxazosin (Cardura), Terazosin (Hytrin),
Tamsulosin (Flomax), Alfuzosin (Uroxatral)
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Medical Management
5 alpha reductase inhibitor )finasteride :
Proscar(
Reduce size of prostate gland by up to 30 %
Blocks the enzyme of 5 alpha reductase
which is necessary to stop the conversion of
testosterone to dihydroxytestostersone
28. Combination Therapy
Concomitant use of alpha blockers and
5-alpha reductase inhibitors
Should be reserved for patients who
are at significant risk of progression
and adverse outcome
Poor surgical candidate
Patient wants to avoid surgery
Significant cost associated with dual
medications
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Medical Management
Herbal therapy –
saw palmetto fruit –
use to improve
urinary symptoms
and urinary flow
Problem with herbal
therapy – long term
effectiveness
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Preoperative care
Antibiotics
Allow pt to discuss concerns about
surgery on sexual functioning
Prostatic surgery may result in
retrograde ejaculation
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Postoperative Care
Monitoring
Continuous irrigation & maintain catheter
patency
Blood clots and hematuria are expected for
the first 24-36 hours
After catheter is removed – check for urinary
retention and urinary stream
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Discharge planning
Catheter care
Managing urinary incontinence
Oral fluid intake – 2,000-3,000 cc per day
Observe for s/s of urinary tract infection
Prevent constipation
Avoid lifting
No driving or intercourse after surgery