An analysis of polls on weight gain after smoking cessation. Explanation based on recent scientific studies of the effects of pharmacology of nicotine and its withdrawal on neurotransmitters, sympathetic nervous system and thermogenesis of white adipose tissue.

1. ANALYSIS OF POLL RESULT
ON
WEIGHT GAIN
AFTER
SMOKING CESSATION
By
Kevin KF Ng, MD, PhD.
Former Associate Professor of Medicine
Division of Clinical Pharmacology
University of Miami, Miami, FL., USA.
Email: kevinng68@gmail.com
A Slide Presentation for HealthCare Providers May 2022

2. Relative change in weight (%) in one year after
smoking cessation (2018)
https://bmjopen.bmj.com/content/8/12/e023987
4.10

3. Ten-year weight gain in smokers who quit, smokers who continued smoking
and never smokers in the United States, NHANES 2003–2012 (2015)
https://www.nature.com/articles/ijo2015127
never smokers quitters

5. Why do cigarette smokers gain weight when they quit smoking?
Results of 76 votes in LinkedIn post

6. Analysis of some 2,435 viewers on the post

7. Comment
▪ Weight gain on quitting cigarette is due to nicotine withdrawal.
▪ Nicotine withdrawal results in:
▪ Imbalance of neurotransmitters in the brain
▪ Dysregulation of the sympathetic nervous system
▪ Dysregulation of thermogenesis in white adipose tissue.
▪ Nicotine withdrawal is manifested in:
▪ Food indulgence
▪ Depression
▪ Weight gain

8. Pharmacology of Nicotine
Brain
Sympathetic
Nervous
system
White adipose tissue
©DRKEVINNG

9. Effects of nicotine withdrawal
©DRKEVINNG
CAUSE OF WEIGHT GAIN

10. ANY QUESTION?
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