2. Distribution of body fluids
Intra cellular
Extra cellular O
out of total body water two third (40% of bodyweight)
is intracellular fluid & one third (20% of weight) is
intracellular fluid & one third (20% of body weight) is
extracellular fluid.
5. Movements of body fluids
Osmosis
Diffusion
Filtration
Active transport
6.
7. osmosis
Diffusion of fluid through a semi permeable
membrane from a solution with a low solute
concentration to a solution with a higher solute
concentration until there is an equal concentration of
fluid on both sides of the membrane
8. diffusion
The process by which solutes move from an area of
higher concentration to one of the lower
concentration, without any expending extra energy
9. Active transport
The physiologic pump that moves fluid from an area of
lower concentration to one of higher concentration;
active transport requires ATP (adenosine
triphosphate) for energy
10. filtration
: Passage through a filter or through a material that
prevents passage of certain molecules, e.g. capillary
wall, blood–brain barrier, radiographic grid.
15. Lymphatic system
It plays an important role in returning excess fluid and
protein from the interstitial spaces to the blood
Kidneys
Maintain fluid volume and the concentration of
urine by filtering the ecf
16. Nervous system
When ecf increases mechanoreceptors in the wall of
the left atrium respond to atria distension by
increasing cardiac stroke volume and triggering a
sympathetic responses to kidney
17. Fluid imbalances
Extra cellular fluid volume deficit
Decrease in the interstitial and extra cellular fluid.
Risk factors
Clinical manifestation
management
19. extra cellular fluid volume shift
Basically a change in the location of extra cellular fluid
between intra vascular and interstitial fluid
20. Intra cellular fluid volume excess
Water intoxication hypo osmolar disorders result from
either water excess or solute deficit and are mainly due
to sodium loss
26. Laboratory findings
:
Increased Osmolality.
Increased or normal serum sodium level.
BUN (> 25 mg/d1)
Hyperglycaemia (> 120 mg / dl)
Elevated hematocrit (>55%), Increased Specific gravity.
27. Medical Management:
Pharmacologic Management
:
An intravenous solution of 5% Dextrose in water (D5W)
or 5% Dextrose in 0.2% saline (D5/0.2% Nacl) may be
prescribed.
If haemorrhage is the cause of ECFVD blood
replacement may be necessary if blood losses greater
than 1L.
In situation in which the blood losses are less than
1L, normal saline & lactated Ringers solution may be
used to restore fluid volume.