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VIRUS MORPHOLOGY & CLASSIFICATION ELIZABETH P. QUILES, M.D., FPASMAP OUR LADY OF FATIMA UNIVERSITY COLLEGE OF MEDICINE
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STRUCTURE  ,[object Object],[object Object],[object Object],[object Object]
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HELICAL SYMMETRY
ICOSAHEDRAL SYMMETRY
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TERMINOLOGIES ,[object Object],[object Object],[object Object],[object Object]
ATYPICAL VIRUS-LIKE AGENTS   ,[object Object],[object Object]
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Yes No Inflammatory Response Yes No Antibody Response Icosahedral or helical  Amyloid-like  Appearance Yes No Heat Inactivation Yes, encoded by viral genes  Yes, encoded by cellular genes  Protein Yes No Nucleic acid CONVENTIONAL VIRUSES PRIONS FEATURE
VIRUS CLASSIFICATION ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Vaccinia, Variola, Molluscum contangiosum DS, linear Complex + Poxviruses HSV, VZV, CMV, EBV, HHV6 DS, linear Icosahedral + Herpesviruses Hepatitis B virus DS, incomplete circular Icosahedral + Hepadnavirus Adenoviruses DS, linear Icosahedral - Adenovirus HPV, Polyoma DS, circular Icosahedral - Papovavirus B19 virus SS, linear Icosahedral - Parvovirus IMPORTANT VIRUSES DNA STRUCTURE SYMMETRY ENVELOPE FAMILY
Orthoviridae, Bunyaviridae Rhabdoviridae, Paramyxoviridae, Filoviridae SS segmented SS  Enveloped Helical Flaviviridae Arenaviridae Coronaviridae Retroviridae SS SS segmented SS SS diploid Enveloped Unknown or complex Togaviridae SS Enveloped Picornaviridae Astroviridae Caliciviridae Reoviridae SS SS SS DS segmented Naked Icosahedral
GENERAL PRINCIPLES ,[object Object],[object Object],[object Object],[object Object],[object Object]
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Virus morphology & classification

  • 1. VIRUS MORPHOLOGY & CLASSIFICATION ELIZABETH P. QUILES, M.D., FPASMAP OUR LADY OF FATIMA UNIVERSITY COLLEGE OF MEDICINE
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  • 18. Yes No Inflammatory Response Yes No Antibody Response Icosahedral or helical Amyloid-like Appearance Yes No Heat Inactivation Yes, encoded by viral genes Yes, encoded by cellular genes Protein Yes No Nucleic acid CONVENTIONAL VIRUSES PRIONS FEATURE
  • 19.
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  • 21. Vaccinia, Variola, Molluscum contangiosum DS, linear Complex + Poxviruses HSV, VZV, CMV, EBV, HHV6 DS, linear Icosahedral + Herpesviruses Hepatitis B virus DS, incomplete circular Icosahedral + Hepadnavirus Adenoviruses DS, linear Icosahedral - Adenovirus HPV, Polyoma DS, circular Icosahedral - Papovavirus B19 virus SS, linear Icosahedral - Parvovirus IMPORTANT VIRUSES DNA STRUCTURE SYMMETRY ENVELOPE FAMILY
  • 22. Orthoviridae, Bunyaviridae Rhabdoviridae, Paramyxoviridae, Filoviridae SS segmented SS Enveloped Helical Flaviviridae Arenaviridae Coronaviridae Retroviridae SS SS segmented SS SS diploid Enveloped Unknown or complex Togaviridae SS Enveloped Picornaviridae Astroviridae Caliciviridae Reoviridae SS SS SS DS segmented Naked Icosahedral
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