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Placental Abnormalities and
Hemorrhagic Complications
1. Antepartum Hemorrhage (APH)
2. Postpartum Hemorrhage (PPH)
3. Ectopic Pregnancy
4. Abortion
2. Postpartum Hemorrhage (PPH)
• Postpartum Hemorrhage (PPH) is a
blood loss after delivery greater than:
- 500 mL for vaginal delivery, and
- 1,000 mL for cesarean delivery,
- with 10% drop in hematocrit
• PPH is responsible for around 25% of
maternal mortality.
PPH Classification
• PPH is classified into:
− Primary (early) occurs
within the first 24 hours
after delivery.
− Secondary (late) occurs
after 24 hours post-birth to 6
weeks after delivery.
PPH Risk factors
• Antepartum hemorrhage in this pregnancy.
• Enlargement Uterus Due to Macrosomia or Multiple fetuses.
• Pre-eclampsia.
• Previous PPH.
• Maternal obesity.
• Uterine abnormalities and Surgery.
• Maternal age (35 years or older).
• Maternal anemia.
• Operative vaginal delivery (Use of forceps or vacuum).
• Induction of labor.
• Prolonged first and second stage of labor (over 12 hours
labor).
• Infections.
• Anemia
Forceps Birth Vacuum Birth
PPH Common Causes
The causes of PPH have been described as the
"four T"
1. Tone: uterine atony (“70%” failure of the uterus
to contract properly after delivery).
2. Trauma: lacerations of the uterus, cervix, or
vagina, and uterus inversion.
3. Tissue: retained placenta.
4. Thrombin: Coagulation abnormalities.
1. Tone:
• Once a baby is delivered, the uterus normally continues to
contract (tightening of uterine muscles) and expels the
placenta.
• After the placenta is delivered, these contractions help
compress the bleeding vessels in the area where the
placenta was attached.
• If the uterus does not contract strongly enough, called
uterine atony, these blood vessels bleed freely and
haemorrhage occurs.
• This is the most common cause of postpartum
haemorrhage.
2. Trauma: Lacerations, hematomas, injury, rupture of
the uterus, cervix, or vagina. And uterus inversion.
3. Tissue: If small pieces of the placenta remain
attached, bleeding is also likely. Or placenta tissues
attack and enter the uterine tissues.
4. Thrombin: Coagulation abnormalities due to many
causes as; HELLP Syndrome, Amniotic fluid
embolism, Vitamin K deficiency.
PPH Prevention
• Detect any abnormality (anemia, diabetes…) before the
delivery and try to control it.
• Ensure that the bladder of the mother is empty since a full
bladder makes it more difficult for the uterus to contract.
• We should know the mother’s blood type.
• IV access should be maintained.
• Slow IV infusion.
• Oxytocin medication (A drug used to stimulate uterine
contractions and control bleeding).
• Oxytocin should be routinely used in the third stage of labor.
• Massage the mother’s uterus to help it contract.
PPH Management
Tone
• Massage
• Drugs (Oxytocin)
Thrombin
• Drugs (according to
the cause)
• Platelet and blood
transfusion
Tissue
• Drugs (Oxytocin)
• Manual removal of retained
placenta
• Uterine curettage
Trauma
• Manual fixation of
uterus inversion
• Repair the rupture
and laceration
Uterine
curettage
Uterus inversion and how to fix it back
Uterine massage
Manual Removal of
the Placenta
PPH Management
• Large-bore intravenous access, and increase
oxytocin.
• Uterus Relaxation Agent
• A blood clotting medication.
• Transfuse blood.
• Bakri Balloon.
• Laparotomy: Surgery to open the abdomen to find
the cause of bleeding.
• If the blood doesn’t stop; Hysterectomy should be
Done (This is always a last resort in all condition).
Bakri
Balloon
3. Ectopic Pregnancy
• An ectopic pregnancy is the implanting
of the zygote somewhere other than the
inner endometrial lining of the uterus
(pregnancy that occurs outside the
uterus).
• It occurs in 1%-2% of all pregnancies.
• It is life-threatening to the mother.
17
3. Ectopic Pregnancy
• The vast majority of ectopic
pregnancies occur in the fallopian
tube “tubal pregnancy’’ (95%), but the
fertilized ovum can also implant in
the ovary, cervix, or abdominal cavity
(5%).
• Doctors usually discover it between
week 5 and week 14 of pregnancy . 18
19
Sites of ectopic pregnancy
20
21
Bleeding due to ectopic pregnancy
Ectopic Pregnancy symptoms
• The first warning sign of an ectopic pregnancy is pelvic
pain.
• Abnormal vaginal bleeding.
• Abdominal pain, typically just in one side, which can
range from mild to severe.
• An absent of menstruation (amenorrhea), and other
symptoms of pregnancy.
• Shoulder pain (unknown why).
• If the fallopian tube ruptures, the pain and bleeding
could be severe enough to cause fainting.
• Rectal pressure.
22
Ectopic Pregnancy Causes
• The most common cause is damaged fallopian tube.
• Zygote abnormality.
• Previous ectopic pregnancy.
• Sexual diseases (typically chlamydia).
• Reproductive organs infections and inflammations.
• Smoking.
• Endometriosis (abnormal uterus lining).
• Using fertility drugs.
• Getting pregnant while having an intrauterine device
(IUD).
23
Intrauterine
device (IUD)
24
Ectopic Pregnancy Complications
• The major health risk of ectopic
pregnancy is rupture leading to
internal bleeding.
• Decreased fertility related to removal
of fallopian tube.
25
Ectopic Pregnancy Management
• In early stage; a medication used to stop
the egg developing. The pregnancy
tissue is then absorbed into the woman’s
body.
• In more advanced stage; a surgery is
required to remove the egg or Embryo.
26
Ectopic Pregnancy Management
• If the fallopian tube has ruptured,
emergency surgery is necessary to
stop the bleeding and fix the tube.
• In some cases, the fallopian tube and
ovary may be damaged and will have
to be removed.
27
Ectopic Pregnancy Management
• The hCG level will need to be rechecked
on a regular basis until it reaches zero if
the entire fallopian tube did not removed.
• An hCG level that remains high could
indicate that the ectopic tissue was not
entirely removed, which would require
another surgery or medical management.
28

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Postpartum Hemorrhage (PPH) and Ectopic Pregnancy

  • 1.
  • 2. Placental Abnormalities and Hemorrhagic Complications 1. Antepartum Hemorrhage (APH) 2. Postpartum Hemorrhage (PPH) 3. Ectopic Pregnancy 4. Abortion
  • 3. 2. Postpartum Hemorrhage (PPH) • Postpartum Hemorrhage (PPH) is a blood loss after delivery greater than: - 500 mL for vaginal delivery, and - 1,000 mL for cesarean delivery, - with 10% drop in hematocrit • PPH is responsible for around 25% of maternal mortality.
  • 4. PPH Classification • PPH is classified into: − Primary (early) occurs within the first 24 hours after delivery. − Secondary (late) occurs after 24 hours post-birth to 6 weeks after delivery.
  • 5. PPH Risk factors • Antepartum hemorrhage in this pregnancy. • Enlargement Uterus Due to Macrosomia or Multiple fetuses. • Pre-eclampsia. • Previous PPH. • Maternal obesity. • Uterine abnormalities and Surgery. • Maternal age (35 years or older). • Maternal anemia. • Operative vaginal delivery (Use of forceps or vacuum). • Induction of labor. • Prolonged first and second stage of labor (over 12 hours labor). • Infections. • Anemia
  • 7. PPH Common Causes The causes of PPH have been described as the "four T" 1. Tone: uterine atony (“70%” failure of the uterus to contract properly after delivery). 2. Trauma: lacerations of the uterus, cervix, or vagina, and uterus inversion. 3. Tissue: retained placenta. 4. Thrombin: Coagulation abnormalities.
  • 8. 1. Tone: • Once a baby is delivered, the uterus normally continues to contract (tightening of uterine muscles) and expels the placenta. • After the placenta is delivered, these contractions help compress the bleeding vessels in the area where the placenta was attached. • If the uterus does not contract strongly enough, called uterine atony, these blood vessels bleed freely and haemorrhage occurs. • This is the most common cause of postpartum haemorrhage.
  • 9. 2. Trauma: Lacerations, hematomas, injury, rupture of the uterus, cervix, or vagina. And uterus inversion. 3. Tissue: If small pieces of the placenta remain attached, bleeding is also likely. Or placenta tissues attack and enter the uterine tissues. 4. Thrombin: Coagulation abnormalities due to many causes as; HELLP Syndrome, Amniotic fluid embolism, Vitamin K deficiency.
  • 10. PPH Prevention • Detect any abnormality (anemia, diabetes…) before the delivery and try to control it. • Ensure that the bladder of the mother is empty since a full bladder makes it more difficult for the uterus to contract. • We should know the mother’s blood type. • IV access should be maintained. • Slow IV infusion. • Oxytocin medication (A drug used to stimulate uterine contractions and control bleeding). • Oxytocin should be routinely used in the third stage of labor. • Massage the mother’s uterus to help it contract.
  • 11. PPH Management Tone • Massage • Drugs (Oxytocin) Thrombin • Drugs (according to the cause) • Platelet and blood transfusion Tissue • Drugs (Oxytocin) • Manual removal of retained placenta • Uterine curettage Trauma • Manual fixation of uterus inversion • Repair the rupture and laceration
  • 13. Uterus inversion and how to fix it back
  • 15. PPH Management • Large-bore intravenous access, and increase oxytocin. • Uterus Relaxation Agent • A blood clotting medication. • Transfuse blood. • Bakri Balloon. • Laparotomy: Surgery to open the abdomen to find the cause of bleeding. • If the blood doesn’t stop; Hysterectomy should be Done (This is always a last resort in all condition).
  • 17. 3. Ectopic Pregnancy • An ectopic pregnancy is the implanting of the zygote somewhere other than the inner endometrial lining of the uterus (pregnancy that occurs outside the uterus). • It occurs in 1%-2% of all pregnancies. • It is life-threatening to the mother. 17
  • 18. 3. Ectopic Pregnancy • The vast majority of ectopic pregnancies occur in the fallopian tube “tubal pregnancy’’ (95%), but the fertilized ovum can also implant in the ovary, cervix, or abdominal cavity (5%). • Doctors usually discover it between week 5 and week 14 of pregnancy . 18
  • 19. 19
  • 20. Sites of ectopic pregnancy 20
  • 21. 21 Bleeding due to ectopic pregnancy
  • 22. Ectopic Pregnancy symptoms • The first warning sign of an ectopic pregnancy is pelvic pain. • Abnormal vaginal bleeding. • Abdominal pain, typically just in one side, which can range from mild to severe. • An absent of menstruation (amenorrhea), and other symptoms of pregnancy. • Shoulder pain (unknown why). • If the fallopian tube ruptures, the pain and bleeding could be severe enough to cause fainting. • Rectal pressure. 22
  • 23. Ectopic Pregnancy Causes • The most common cause is damaged fallopian tube. • Zygote abnormality. • Previous ectopic pregnancy. • Sexual diseases (typically chlamydia). • Reproductive organs infections and inflammations. • Smoking. • Endometriosis (abnormal uterus lining). • Using fertility drugs. • Getting pregnant while having an intrauterine device (IUD). 23
  • 25. Ectopic Pregnancy Complications • The major health risk of ectopic pregnancy is rupture leading to internal bleeding. • Decreased fertility related to removal of fallopian tube. 25
  • 26. Ectopic Pregnancy Management • In early stage; a medication used to stop the egg developing. The pregnancy tissue is then absorbed into the woman’s body. • In more advanced stage; a surgery is required to remove the egg or Embryo. 26
  • 27. Ectopic Pregnancy Management • If the fallopian tube has ruptured, emergency surgery is necessary to stop the bleeding and fix the tube. • In some cases, the fallopian tube and ovary may be damaged and will have to be removed. 27
  • 28. Ectopic Pregnancy Management • The hCG level will need to be rechecked on a regular basis until it reaches zero if the entire fallopian tube did not removed. • An hCG level that remains high could indicate that the ectopic tissue was not entirely removed, which would require another surgery or medical management. 28