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Antidepressants, Serotonin, and Depression Symptoms

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i. Most antidepressants act on aspects of serotonergic synapses by affecting serotonin levels in the brain. ii. Drugs that affect serotonergic synapses can have immediate effects on depression symptoms, even though reduced serotonin levels are not always present in individuals with major depression. iii. Statements i and iii regarding the relationship between monoamine neurotransmitters and mood disorders are true.

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Which of the following statements regarding the relationship between monoamine neurotransmitters and mood disorders is/are true? i. Most antidepressants act on aspects of serotonergic synapses ii. Individuals with major depression always have reduced serotonin levels iii. Drugs that affect serotonergic synapses have immediate effects on depression symptoms a. i only b. i and ii only c. i and iii only d. ii and iii only e. i, ii, and iii

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