This document provides recommendations for evidence-based resources to research the disease targeted by a drug. It suggests exploring UpToDate and DynaMed, which consolidate the latest research, evidence, guidelines, and expert opinions. UpToDate provides disease topic pages covering epidemiology, risk factors, and treatments. DynaMed allows keyword searching across medical journals and ebooks. The document advises beginning with a disease overview in these sources, noting related drugs sections. It also recommends limiting searches to focus on specific evidence types like systematic reviews or treatment guidelines relevant to understanding the disease the drug Peramivir targets, which is Influenza.

1. Evidence Based
Guidelines
Need to find out more
about the disease
pathobiology your
drug is targeting?
Consider using
Evidence Based Guidelines,
Summaries and Support Systems
See our ACQ Subject Guide
Focus:

2. Evidence Based Resources
The second tab of the ACQ Guide suggests some good evidence based resources to try

3. Let’s explore two of these for reviewing the disease the drug
Peramivir targets - Influenza
Designed and built as a decision-
support tool at the point of care.
Latest research, evidence, guidelines
and expert opinion combined in a
single source.
Covering prevention, diagnosis,
treatment and prognosis.
Look to the overview monograph for
condition background,
pathophysiology, history and
evaluation.
Provides disease topic pages with
information about epidemiology, risk
factors and treatments.
Also a source for a large collection of
medical ebooks and journals with links
to Medline.
Easy key word searching with capacity
to sort results by source, study type or
treatment specialisation.

4. Begin typing your disease focus to view a range of
recommended terms used within this database

5. Notice results identify source type – look for results that provide a consolidation
of evidence – that is sources higher up the hierarchy of evidence

6. Exploring an available “Disease Overview” can be a good starting point.
Note the focus on “Related Drugs”

7. Use the available limits to focus on specific types of evidence on your disease
Such as a highly relevant
systematic review
Or focus on
Treatment Guidelines

8. Try a search for your disease AND drug for specific references