5. Evolution of damage control in
surgical patients
1908 Pringle: Compression and hepatic packing for
portal venous hemorrhage. Ann Surg 1908;48:541
6. Evolution of damage control in
surgical patients
1983 Stone et al. : Coagulopathy contributed to poor
outcomes. Proposed truncation of laparotomy, reversal of
coagulopathy and then return to OR for definite surgical
repair. Ann Surg : 1983 May; 1979(5) : 532
8. Evolution of damage control in
surgical patients
Burch, et al 1992 Ann Surg : 1992 May;
215 (5) :476
9. Evolution of damage control in
surgical patients
1993 Rotondo et al coined “ Damage Control
Laparotomy “
20 year review : 52% mortality – 40% morbidity
12. Effects of hypothermia
100% mortality if core temp < 32C
Diminished cardiac function
Coagulopathy: clotting cascade is a temp.
dependent reaction, fibrinolysis, platelet
dysfunction/sequestration
13. Acidosis
Lactate production from anaerobic
metabolism
Failure to normalize lactate concentration
by 48 hours, mortality between 86 to 100%
Systemic effects: decreased contractility,
impaired response to catecholamines and
ventricular arrhythmias
Coagulopathy worsened
15. Control or not?
Damage control surgery: an alternative approach
for the management of critically injured patients
Kouraklis G, Spirakos S, Glinavou A Surg Today.
2002;32(3):195-202
…These observations have led to the development
of a new surgical strategy that sacrifices the
completeness of immediate repair in order to
adequately address the combined physiological
impact of trauma and surgery
16. Control or not?
Coagulopathy, hypothermia and acidosis in trauma
patients: the rationale for damage control surgery
De Waele JJ, Vermassen FE. Acta Chir Belg.
2002 Oct;102(5):313-6.
Over the past 20 years, it has gradually become
apparent that the results of prolonged and
extensive surgical procedures performed on
critically injured patients are often poor, even in
experienced hands…
17. Damage control
Definite surgery is time-consuming and may be
not executed
Surgical insult may waste functional reserve
Aims:
– Damage control operation
– Resuscitation in SICU
– Planned reoperation in 24-48 hours
18. Damage control in surgical
patients : Who needs it ?
Bleeding caused by coagulopathy
Severe metabolic acidosis (pH <7.3)
Hypothermia during operation (T° <34°)
Shock
Massive transfusion : >10 units PRBCs
19. Damage control in surgical
patients : Who needs it ?
Surgeon gestalt : --High energy blunt torso trauma
–Multiple visceral injuries – Multiple torso
penetrating injuries – Multi regonal injuries
Inability to control the haemorrhage (hepatic,
retroperitoneal, pelvic, thoracic or cervical)
Inability to formally close the abdomen because of
intestinal edema
24. Technique of damage control :Components
A- Abbreviated surgery for rapid control of
hemorrhage and contamination
B- Resuscitation in ICU with correction of
physiological abnormalities
C- Subsequent definitive repair and
abdominal wall closure
25. Damage Control Surgery
Phase I
– Rapid termination of operative procedure
– Arrest of bleeding
– Removal of contamination
Phase II
– Correction of physiologic abnormalities
– Acidosis, hypothermia, coagulopathy
Phase III
– Definitive surgery
26. What is different?
Surgical dogma: complete the operation
– 1908: Pringle packing of liver injury
– Fell out of favour, not used in Vietnam war
– 1981: Feliciano 90% survival by packing in severe liver
injury
– 1983: Stone abbreviated laparotomy, 11/17 survivors
Rotundo: damage control surgery, 1990s
27. Damage control : Technique
A-Abbreviated resuscitative surgery :
-- Do only necessary procedures
1-- Control bleeding :
0- Ligation
0- Shunting
0- Packing
2--Excision/Stapling of bowel to prevent further
contamination
3-- Temporary closure of abdominal wall defect
--Limit heat loss
28. Abdomen
Liver packing
Ligation of blood vessels
Placement of intraluminal shunts
Chest tubes in to aorta or IVC
Inflatable balloon catheters
29. Abdomen II
Resect hollow viscus with a stapler
Biliopancreatic injuries by closed suction drainage
Ligation of ureter or tube ureterostomy
Formal closure
– Abdominal compartment syndrome
– ARDS
– MOF
Closure of skin, mesh
30. Damage Control Surgery
•Prep surgical field from neck to knees and from flank to
flank
•Longitudinal incision form xiphoid to pubis
•Cell saver to reinfuse autologous blood if possible
•Urgent exploration with packing of all four quadrants of
abdomen
•Serial controlled examination of each quadrant and organ
•Pack liver injuries and splenic injuries
•Control vascular injuries
•Close off perforated gastrointestinal tract
•Examine retroperitoneal structures
31. DAMAGE CONTROL SURGERY
•Avoid hypotension, hypothermia, acidosis
leading to coagulopathy
•Repair or ligate vascular injuries
•Splenectomy if injured
•Repair or resect intestines
•Pack liver hemorrhage
•Pack and leave open abdomen if necessary
32.
33.
34.
35. Damage control in surgical
patients
1- Control of bleeding :
* Temporary stenting
* Packing/ Tamponade
* Angio-embolization
* Recombinant FactorVIIa
* Ligation of vessels rather than repair
45. Damage control: Control of bleeding
Recombinant Factor VIIa :
--Dilutional coagulopathy
--Stored blood product
--Clot promotion; activates factor Xa
--Throbo-embolic risk ?
46. Damage control : Contamination control
2- Contamination control
– Hollow viscus ligation instead of repair
– External tube drainage of biliary and pancreatic
injury instead of pancreatoduodenectomy
– ERCP for diagnosis and treatment
– Avoidance of formal colostomy
58. Resuscitation
End points of resuscitation
Adequate urinary output
Haematocrit >20%
Restoration of vital signs
- Normal mixed venous O2
- Normal or high cardiac output
Clearance of lactic acidosis/base deficit
Normalize pH preferably without NaHCO3
59. Resuscitation
IV volume restoration best accomplished
using FFP in 1:1 ratio with PRBCs
Crystalloid use is more limited
60. Metabolic acidosis
Usually correct on its own once the patient
is warm and volume resuscitated
O2 debt repaid
Anaerobic Aerobic metabolism
Need for NaHCO3 is rare – but
If cadiotonic agents are needed, keep pH>7.2
61. Pitfalls
Continued hemorrhage:
Especially in a warm non-coagulopathic patient
Vessels that were constricted and NOT ligated at the time of
operation may begin bleeding as the patient is warmed and
resuscitated
Return to the OR
63. C- Definitive repair
When to return to the OR ?
-- When patient is warm and acidosis and
coagulopathy has been corrected
-- 36-72 hours had reduced risk of
rebleeding for patients with perihepatic
packing
64. C- Definitive repair
Bowel injuries
-- Colostomy or anastomosis ?
* Delayed anastomosis as safe as colostomy
-- Stapled or hand sewn anastomosis
* Controversial
* Surgeon comfort with the technique
* Presence of bowel oedema
Oedematous bowel is more prone to anastomotic leak
Wait for oedema to resolve to do anastomosis
66. C- Definitive repair : Closure
Vaccuom closure
92% of patients closed in 9.9 _+ 1.9 days
Garner et al, Am J Surg 2001; 132 : 630
67. Closure
When the abdomen can not be closed
Bowel becomes “stuck”
Multiple solutions :
* Permanent mesh
* Absorbable mesh
* Prosthetic patches
* Bioprosthetic patches
* STSG directly on granulated bowel
* Component separation
68. Summary
Organ injury patterns and survival from
penetrating abdominal injury have remained
similar over the last decade
Death from refractory hemorrhage in the
first 24 hours remain the common cause of
mortality.
69. Summary
DCS and use of open abdomen are being
used more frequently with imporved
survival, but result in more morbidity.
Evidence-based analysis will be the ultimate
guideline to determine the optimal
management.