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HERBS AND
SUPPLEMENTS
GROUP 4
Orallo, Romella Sheikah B.
Cuarteros, Glenn
Capilot, Joefel
Lacio, Christine May
Hemoros, Kylah
Objectives:
• To know their families, scientific names, methods,
pharmaceutical use, their drug interactions and side effects of:
 GINKGO
 GARLIC
 COCONUT OIL
 BARLEY
 COD LIVER OIL
GINKGO
SHEIKAH
Scientific Classification
• Kingdom:
Plantae
• Division:
Ginkgophyta
• Class:
Ginkgopsida
• Order:
Ginkgoales
• Family:
Ginkgoacea
• Genus:
Ginkgo
• Species:
Gingko biloba
History of Cultivation
• Gingko has long been cultivated in China; some planted trees at
temples are believed to be over 1,500 years old
• The first record of Europeans encountering it is in 1690 in Japan
temple gardens, where the tree was seen by the German botanist
Engelbert Kaempfer
• Because of its status in Buddhism and Confucianism the gingko is also
widely planted in Korea and parts of Japan; in both areas, some
naturalization has occurred, w/ ginkgo’s seeding into natural forest.
• Ginkgo are Male cultivar (cultivated species)
• The popular cultivar “Autumn Gold” is a clone of male plant
27 Synonym Names of Ginkgo Based
On
NCBI Synonym Names of Ginko
biloba
Habitat
• It is native to China and Japan
• It is also cultivated ornamentally in many Temperate
Regions
• It is found under moist and moderately warm climate
• The earliest fossils were found in the Permian Period of
the Paleozoic era 270 million years ago
• Most diverse during the Jurassic Period
Plant Body
• Stem
• Straight (40m)
• Girth (13ft or 4m
wide)
• Bark is deeply
fissured, grayish to
grayish brown colour
• Woody branched
• Slow growing
Characteristics
• The leaves are Bilobed
• The leaf is glabrous, petiolate
and has entire margin
Male Vs. Female Morphology
Male Ginkgo Trees
• Also known as Dwarf Shoot
or Short Shoot
• Produce pollen in clusters of
pollen sacs that resemble
catkins 3 – 6 cm (abot 1 ¼ - 2
¼ ) long
Female Ginkgo Trees
• Also known as Female
Strobilus or Long Shoot
• Pairs of green ovules are
borne on female trees on
stalk 4 – 5 cm (1 ½ - 2) long
• Usually one ovule develops
in a seed
Male Microsporophyll
Female Microsporophyll
Leaf of Ginkgo
Male Shoot
• The petiole is short and
thicker
• Has strobilus
• Leaf is enfolded at the
base
• Shorter and thicker than
female
Female Shoot
• The petiole is long and thin
• Two ovules (one will be used)
• The leaf is broaden
Phytochemicals
Diterpene Lactones
• Ginkgolides A
• Ginkgolides B
• Ginkgolides C
• Ginkgolides J
• Ginkgolides M
Flavonoids
• About 40 flavonoids have been
isolated from the leaves
including:
1. GLYCOSIDESOF KAEMPFEROL,
2. QUERCETIN
3. ISORHAMNEIN DERIVATIVES
MAJOR CONSTITUENTS
Ginkgolides( A,B,C,J,M)
Kaempferol Quercetin
Clinical Uses
• Antiasthmatic
• Bronchodilator
• Treatment of chilblains
• Dementia and Alzheimer’s Disease
• Vertigo
• Headache
• Anxiety
• Apathy
• It’s leaf extract used as Dietary supplements
• It can enhance Cognitive function
Side Effects
• Blood circulation disorders and those taking anticoagulant such as
aspirin or warfin
• Increase of bleeding, gastrointestinal discomfort, nausea, vomiting,
diarrhoea, headache, dizziness, heart palpitation and restlessness
• Ginkgo should be used with caution when combined w/ other herbs
known to increase bleeding
• The effects of ginkgo on pregnant women may include increased
bleeding time and it should be avoided during lactation because of in
adequate safety evidence
GARLIC
ATE PAW
Scientific Classification
• Botanical Name:
Allium sativum linn.
• Family:
Liliaceae
• English Name:
Garlic
• Urdu Name:
Lassan
• Part Used:
Bulb
• Chemical Class:
Flavonoid
Glycosides
Alkaloids
Chemical Constituents
• Allicin (Yellowish Liquid)
• Aliin
• Mucilage
• Albumin
• Alpha – Glutamyl Pectides
• Volatile Oils
• Amino Acids as: Methionine, Lucine, Cysteine
• Vitamin C
USES
• Anti – cancer
• Flavouring Agent
• Treat Diabetes
• Prevent Atheroseclerosis
• For treating respiratory disease as bronchitis, asthma, tuberculosis
• Expectorant
• Stimulant
• Hypertension
• Skin treatment in fungal infections
Dosage
For B.P extract 600 – 1200mg, 3.5 – 29mg weekly
For cancer prevention, For Fungal infections 0.4%
Toxicolog
yWeight loss, Increase liver spleen ratio, skin burns internal bleeding
Route of Administration
Oral
Topical
Solubility
Allicin is soluble in Alcohol & Ether
Side Effects
• Some people suffer from allergic reactions
• May cause severe burns if topically applied to skin
• FDA Study approves may cause GIT Discomfort, Diarhoeae
• In children cause diaper rashes, blister formation
• Dizziness
• Menstrual Irregularities
Drug Interaction
• Iso – niazids (Nydrazid) garlic reduce their absorption
• Nucleoside Revers Etranscritase Inhibitors (Nits breakdown in body
REIS) as anti aids garlic increase their breakdown in body so will
reduce their effectiveness
• Birth control pills contain estrogen garlic increase its breakdown in
body so reduce their effectiveness
• Cyclosporine action is so reduced if garlic is taken because it increase
its breakdown
Contraindications
• Possibly safe during pregnancy for short term use but can be unsafe
in medicinal amount
• Also unsafe for children in high dosage
BARLEY
joefel
• Botanical Source:
Hordeum vulgare
• Common Name:
Barley (English)
Javi (Punjabi)
Jao (Urdu)
• Family:
Poaceae
Gramineae
Origin & History
• Orginated in Asia or Europe
• Abyssinia and southern Tibet many kinds of barley grow
naturally without cultivation
• Cultivated barley originated from Aberg
Cultivation in Pakistan
• Barley planted on about 227000 ha
• Produced 158000 tons of grains
• Average yield 696 kg/ha
• Producing districts Bir, Bahawalnagar, Khuzdar, Chitral and
Thatta
Climat
e Temperate regions Climate
 Optimum temperature 15 – 20 C
 Low temperature for flowering
Soil
 Clay loam soils
 Less fertile soils
 Marginal lands
Uses
• High cholesterol
• Stomach cancer
• Inflammatory bowel disease (ulcerative colitis)
• Weight loss
• Bronchitis
• Diarrhoea
• Boils
• Increasing strength and energy
Side Effects
•Stomach upset
•Allergic Reaction
•Not barely eaten in high
amount of barley
during pregnancy
Land Preparation & Time of Sowing
Land Preparation
• 2 -3 Ploughing with planking
• To remove the stubbles use
rotavator or disc harrow
Time of Sowing
• Rainfed Areas
15 Oct – 10 Nov
• Irrigated Areas
1st Nove – 25 Nov.
Seed Rate & Method of Sowing
Seed Rate
• Rainfed Areas:
50 – 60 kg/ha
• Irrigated Areas:
70 – 80 kg/ha
Method of Sowing
• Drilled Method
• Broadcast
Irrigation & Fertilizer
Irrigation
• 2 – 4 irrigation
• 1st irrigation is after 12 – 18
days of Germination
• 2nd irrigation at Tillering
stage
• 3rd irrigation at Grain
development stage
Fertilizer
• 1 bag of DAP
• 1 bag of urea
Weeding & Spacing
Weeding
•Weed – free seeds
•Well – prepared seedbed
Spacing
•Rows 20 – 40cm
•Depth 4 – 7 cm
Insect, Pest, Disease & Cultivar
Disease & Insect
• Losoe smut
• Bunt attact
• Powdery mildew
• Army worms
• Aphid
Cultivar
• Tj – 70
• NWFP
• Frontier – 87
• Sindh
• Clipper
• Neelum
Harvesting
• Barley is ready to harvest before wheat
• Harvest at physiological maturity
• Harvest mid of March to end of April
Storage of Barley
Threshing
• Care should be taken during
threshing the grains so that
they do not break because
damaged grains get more
attack of insects during
storage
Moisture Contents
• Should not be more than
10% when storing
COCONUT OIL
GLENN
Thyroid condition
Energy
Boosting the immune system
• Side Effects:
High cholesterol
Increase levels of bad low –
density lipoprotein cholesterol
• Drug Interaction:
There are no known medication
interactions for coconut oil
• Botanical Origin:
Cocos nucifera
• Family:
Arecaceae
• Clinical Use:
Diabetes
Chronic Fatigue
Crohn’s Disease
Irritable Bowel Syndrome (IBS)
Alzheimer’s Disease
Breast cancer
Preparation
• Step 1: Extract the flesh from the coconut. Once you have collected
the flesh from all the coconut, grated it
• Step 2: Extract the coconut milk from the flesh by squeezing it w/
your hands in a muslin cloth. Keep a bowl below the cloth to collect
the liquid.
• Step 3: Once the coconut milk has been extracted, sieve it using a
muslin cloth to remove any impurities
• Step 4: Place the coconut milk in brass vessel (known as Urli in
Malayalam) and put it on fire. Let it cook for 2 to 3 hours, but make
sure the heat is kept low.
• Step 5: Keep stirring it every now and then till the milk becomes
brownish in colour. However, be careful that it doesn’t burn as
coconut milk has a very delicate texture
• Step 6: Once the milk become concentrated, remove it from the fire
and let it cool down. Place the cooled thickened milk in a muslin cloth
and squeeze out the oil. Collect it in a bowl and then store it in a can
or plastic bottle
The homemade coconut oil can last for a year or at least 8 – 10
months. You should place it air right container and don’t leave it out in
the open else it can get contaminated and lost its qualities.
COD LIVER
OIL
KYLA
Cod liver oil is a dietary supplement derived from liver of cod fish
• Synonyms:
Oleum morrhi
• Botanical Source:
Gadus morrhua
• Family:
Gadidae
• Geographical Source:
They are prepared in Scotland, Iceland, Germany, Denmark and
Britain
Preparation
I. Liver are removed from the cod fish.
II. Live is cleaned thoroughly to make it free from fatty substances and
attached tissues like gall – bladder
III. The liver are heated in water at about 80 C
IV. The oil exhudes, floats on the top, and separated, washed and
water is removed
V. The dehydrated oil is cooled to separate stearin
VI. The suspended materials are removed centrifugation
Description
• Colour:
Pale yellow thin liquid
• Taste:
Slightly fishy
• Odor:
Fishy
It is freely soluble in chloroform, ether, carbon disulphide and
petroleum ether and slightly soluble in alcohol.
• Chemical Constituents:
I. It contains of Vit A and Vit D
II. The oil contains glyceryl ester of oleic, linoleic, gadoleic, myristic,
Palmitic and other acids
III. Cod liver oil also contains 7% eicosapaenoic acid and
docosahexanoic acid
• Chemical Test:
I. A solution of cod liver oil chloroform is treated with sulphuric acid.
A violet colour changing to purple or brown is formed due to
presence
II. Cod liver oil (1ml) dissolved in chloroform (10ml). Few drops of
saturated solution of antimony trichloride is added to the solution.
A blue coloration is formed due to presence of Vit A
• Uses:
1. The oil is used as a source of vitamins
2. As a nutritive
3. Treatment of Rickets and Tuberculosis
4. The application of cod liver oil ointment on wounds to speeds up the
healing process
5. Omega – 3 fatty acids in cod liver oil reduces the inflammation of the
cells
6. Cod liver oil cures the gastric ulcers and prevents the development of
duodenal ulcers
7. Reduces cholesterol level
• Storage:
The oil is sensitive to light and air. It should be stored in air tight,
completely filled, coloured containers.
Thank You!!!

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Pharmacognosy: Herbs and supplements

  • 1. HERBS AND SUPPLEMENTS GROUP 4 Orallo, Romella Sheikah B. Cuarteros, Glenn Capilot, Joefel Lacio, Christine May Hemoros, Kylah
  • 2.
  • 3. Objectives: • To know their families, scientific names, methods, pharmaceutical use, their drug interactions and side effects of:  GINKGO  GARLIC  COCONUT OIL  BARLEY  COD LIVER OIL
  • 5. Scientific Classification • Kingdom: Plantae • Division: Ginkgophyta • Class: Ginkgopsida • Order: Ginkgoales • Family: Ginkgoacea • Genus: Ginkgo • Species: Gingko biloba
  • 6. History of Cultivation • Gingko has long been cultivated in China; some planted trees at temples are believed to be over 1,500 years old • The first record of Europeans encountering it is in 1690 in Japan temple gardens, where the tree was seen by the German botanist Engelbert Kaempfer • Because of its status in Buddhism and Confucianism the gingko is also widely planted in Korea and parts of Japan; in both areas, some naturalization has occurred, w/ ginkgo’s seeding into natural forest. • Ginkgo are Male cultivar (cultivated species) • The popular cultivar “Autumn Gold” is a clone of male plant
  • 7. 27 Synonym Names of Ginkgo Based On
  • 8. NCBI Synonym Names of Ginko biloba
  • 9. Habitat • It is native to China and Japan • It is also cultivated ornamentally in many Temperate Regions • It is found under moist and moderately warm climate • The earliest fossils were found in the Permian Period of the Paleozoic era 270 million years ago • Most diverse during the Jurassic Period
  • 10.
  • 11. Plant Body • Stem • Straight (40m) • Girth (13ft or 4m wide) • Bark is deeply fissured, grayish to grayish brown colour • Woody branched • Slow growing
  • 12. Characteristics • The leaves are Bilobed • The leaf is glabrous, petiolate and has entire margin
  • 13. Male Vs. Female Morphology Male Ginkgo Trees • Also known as Dwarf Shoot or Short Shoot • Produce pollen in clusters of pollen sacs that resemble catkins 3 – 6 cm (abot 1 ¼ - 2 ¼ ) long Female Ginkgo Trees • Also known as Female Strobilus or Long Shoot • Pairs of green ovules are borne on female trees on stalk 4 – 5 cm (1 ½ - 2) long • Usually one ovule develops in a seed
  • 16.
  • 17. Leaf of Ginkgo Male Shoot • The petiole is short and thicker • Has strobilus • Leaf is enfolded at the base • Shorter and thicker than female Female Shoot • The petiole is long and thin • Two ovules (one will be used) • The leaf is broaden
  • 18.
  • 19. Phytochemicals Diterpene Lactones • Ginkgolides A • Ginkgolides B • Ginkgolides C • Ginkgolides J • Ginkgolides M Flavonoids • About 40 flavonoids have been isolated from the leaves including: 1. GLYCOSIDESOF KAEMPFEROL, 2. QUERCETIN 3. ISORHAMNEIN DERIVATIVES MAJOR CONSTITUENTS
  • 20.
  • 23. Clinical Uses • Antiasthmatic • Bronchodilator • Treatment of chilblains • Dementia and Alzheimer’s Disease • Vertigo • Headache • Anxiety • Apathy • It’s leaf extract used as Dietary supplements • It can enhance Cognitive function
  • 24.
  • 25. Side Effects • Blood circulation disorders and those taking anticoagulant such as aspirin or warfin • Increase of bleeding, gastrointestinal discomfort, nausea, vomiting, diarrhoea, headache, dizziness, heart palpitation and restlessness • Ginkgo should be used with caution when combined w/ other herbs known to increase bleeding • The effects of ginkgo on pregnant women may include increased bleeding time and it should be avoided during lactation because of in adequate safety evidence
  • 26.
  • 28. Scientific Classification • Botanical Name: Allium sativum linn. • Family: Liliaceae • English Name: Garlic • Urdu Name: Lassan • Part Used: Bulb • Chemical Class: Flavonoid Glycosides Alkaloids
  • 29. Chemical Constituents • Allicin (Yellowish Liquid) • Aliin • Mucilage • Albumin • Alpha – Glutamyl Pectides • Volatile Oils • Amino Acids as: Methionine, Lucine, Cysteine • Vitamin C
  • 30. USES • Anti – cancer • Flavouring Agent • Treat Diabetes • Prevent Atheroseclerosis • For treating respiratory disease as bronchitis, asthma, tuberculosis • Expectorant • Stimulant • Hypertension • Skin treatment in fungal infections
  • 31. Dosage For B.P extract 600 – 1200mg, 3.5 – 29mg weekly For cancer prevention, For Fungal infections 0.4% Toxicolog yWeight loss, Increase liver spleen ratio, skin burns internal bleeding Route of Administration Oral Topical Solubility Allicin is soluble in Alcohol & Ether
  • 32. Side Effects • Some people suffer from allergic reactions • May cause severe burns if topically applied to skin • FDA Study approves may cause GIT Discomfort, Diarhoeae • In children cause diaper rashes, blister formation • Dizziness • Menstrual Irregularities
  • 33. Drug Interaction • Iso – niazids (Nydrazid) garlic reduce their absorption • Nucleoside Revers Etranscritase Inhibitors (Nits breakdown in body REIS) as anti aids garlic increase their breakdown in body so will reduce their effectiveness • Birth control pills contain estrogen garlic increase its breakdown in body so reduce their effectiveness • Cyclosporine action is so reduced if garlic is taken because it increase its breakdown
  • 34. Contraindications • Possibly safe during pregnancy for short term use but can be unsafe in medicinal amount • Also unsafe for children in high dosage
  • 36. • Botanical Source: Hordeum vulgare • Common Name: Barley (English) Javi (Punjabi) Jao (Urdu) • Family: Poaceae Gramineae
  • 37. Origin & History • Orginated in Asia or Europe • Abyssinia and southern Tibet many kinds of barley grow naturally without cultivation • Cultivated barley originated from Aberg
  • 38. Cultivation in Pakistan • Barley planted on about 227000 ha • Produced 158000 tons of grains • Average yield 696 kg/ha • Producing districts Bir, Bahawalnagar, Khuzdar, Chitral and Thatta
  • 39. Climat e Temperate regions Climate  Optimum temperature 15 – 20 C  Low temperature for flowering Soil  Clay loam soils  Less fertile soils  Marginal lands
  • 40. Uses • High cholesterol • Stomach cancer • Inflammatory bowel disease (ulcerative colitis) • Weight loss • Bronchitis • Diarrhoea • Boils • Increasing strength and energy
  • 41. Side Effects •Stomach upset •Allergic Reaction •Not barely eaten in high amount of barley during pregnancy
  • 42. Land Preparation & Time of Sowing Land Preparation • 2 -3 Ploughing with planking • To remove the stubbles use rotavator or disc harrow Time of Sowing • Rainfed Areas 15 Oct – 10 Nov • Irrigated Areas 1st Nove – 25 Nov.
  • 43. Seed Rate & Method of Sowing Seed Rate • Rainfed Areas: 50 – 60 kg/ha • Irrigated Areas: 70 – 80 kg/ha Method of Sowing • Drilled Method • Broadcast
  • 44. Irrigation & Fertilizer Irrigation • 2 – 4 irrigation • 1st irrigation is after 12 – 18 days of Germination • 2nd irrigation at Tillering stage • 3rd irrigation at Grain development stage Fertilizer • 1 bag of DAP • 1 bag of urea
  • 45. Weeding & Spacing Weeding •Weed – free seeds •Well – prepared seedbed Spacing •Rows 20 – 40cm •Depth 4 – 7 cm
  • 46. Insect, Pest, Disease & Cultivar Disease & Insect • Losoe smut • Bunt attact • Powdery mildew • Army worms • Aphid Cultivar • Tj – 70 • NWFP • Frontier – 87 • Sindh • Clipper • Neelum
  • 47. Harvesting • Barley is ready to harvest before wheat • Harvest at physiological maturity • Harvest mid of March to end of April
  • 48. Storage of Barley Threshing • Care should be taken during threshing the grains so that they do not break because damaged grains get more attack of insects during storage Moisture Contents • Should not be more than 10% when storing
  • 50. Thyroid condition Energy Boosting the immune system • Side Effects: High cholesterol Increase levels of bad low – density lipoprotein cholesterol • Drug Interaction: There are no known medication interactions for coconut oil • Botanical Origin: Cocos nucifera • Family: Arecaceae • Clinical Use: Diabetes Chronic Fatigue Crohn’s Disease Irritable Bowel Syndrome (IBS) Alzheimer’s Disease Breast cancer
  • 51. Preparation • Step 1: Extract the flesh from the coconut. Once you have collected the flesh from all the coconut, grated it • Step 2: Extract the coconut milk from the flesh by squeezing it w/ your hands in a muslin cloth. Keep a bowl below the cloth to collect the liquid. • Step 3: Once the coconut milk has been extracted, sieve it using a muslin cloth to remove any impurities
  • 52. • Step 4: Place the coconut milk in brass vessel (known as Urli in Malayalam) and put it on fire. Let it cook for 2 to 3 hours, but make sure the heat is kept low. • Step 5: Keep stirring it every now and then till the milk becomes brownish in colour. However, be careful that it doesn’t burn as coconut milk has a very delicate texture • Step 6: Once the milk become concentrated, remove it from the fire and let it cool down. Place the cooled thickened milk in a muslin cloth and squeeze out the oil. Collect it in a bowl and then store it in a can or plastic bottle The homemade coconut oil can last for a year or at least 8 – 10 months. You should place it air right container and don’t leave it out in the open else it can get contaminated and lost its qualities.
  • 54. Cod liver oil is a dietary supplement derived from liver of cod fish • Synonyms: Oleum morrhi • Botanical Source: Gadus morrhua • Family: Gadidae • Geographical Source: They are prepared in Scotland, Iceland, Germany, Denmark and Britain
  • 55. Preparation I. Liver are removed from the cod fish. II. Live is cleaned thoroughly to make it free from fatty substances and attached tissues like gall – bladder III. The liver are heated in water at about 80 C IV. The oil exhudes, floats on the top, and separated, washed and water is removed V. The dehydrated oil is cooled to separate stearin VI. The suspended materials are removed centrifugation
  • 56.
  • 57. Description • Colour: Pale yellow thin liquid • Taste: Slightly fishy • Odor: Fishy It is freely soluble in chloroform, ether, carbon disulphide and petroleum ether and slightly soluble in alcohol.
  • 58. • Chemical Constituents: I. It contains of Vit A and Vit D II. The oil contains glyceryl ester of oleic, linoleic, gadoleic, myristic, Palmitic and other acids III. Cod liver oil also contains 7% eicosapaenoic acid and docosahexanoic acid • Chemical Test: I. A solution of cod liver oil chloroform is treated with sulphuric acid. A violet colour changing to purple or brown is formed due to presence II. Cod liver oil (1ml) dissolved in chloroform (10ml). Few drops of saturated solution of antimony trichloride is added to the solution. A blue coloration is formed due to presence of Vit A
  • 59. • Uses: 1. The oil is used as a source of vitamins 2. As a nutritive 3. Treatment of Rickets and Tuberculosis 4. The application of cod liver oil ointment on wounds to speeds up the healing process 5. Omega – 3 fatty acids in cod liver oil reduces the inflammation of the cells 6. Cod liver oil cures the gastric ulcers and prevents the development of duodenal ulcers 7. Reduces cholesterol level • Storage: The oil is sensitive to light and air. It should be stored in air tight, completely filled, coloured containers.