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Acute Renal Failure
Dr. Muhib Sharifi, MD, PhD
ARF
 sudden deterioration in renal function
 Inability of the kidneys to maintain fluid and electrolyte homeostasis
CRITERIA ESTIMATED CCl URINE OUTPUT
Risk eCCl decrease by 25% <0.5 mL/kg/hr for 8 hr
Injury eCCl decrease by 50% <0.5 mL/kg/hr for 16 hr
Failure
eCCl decrease by 75% or eCCl
<35 ml/min/1.73 m2
<0.3 mL/kg/hr for 24 hr or anuric
for 12 hr
Loss Persistent failure >4 wk
End-stage
End-stage renal disease
(persistent failure >3 mo)
Table 529-1 -- PEDIATRIC-MODIFIED RIFLE (PRIFLE) CRITERIA
Acute Renal Failure.pptx

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Acute Renal Failure.pptx

  • 1. Acute Renal Failure Dr. Muhib Sharifi, MD, PhD
  • 2. ARF  sudden deterioration in renal function  Inability of the kidneys to maintain fluid and electrolyte homeostasis CRITERIA ESTIMATED CCl URINE OUTPUT Risk eCCl decrease by 25% <0.5 mL/kg/hr for 8 hr Injury eCCl decrease by 50% <0.5 mL/kg/hr for 16 hr Failure eCCl decrease by 75% or eCCl <35 ml/min/1.73 m2 <0.3 mL/kg/hr for 24 hr or anuric for 12 hr Loss Persistent failure >4 wk End-stage End-stage renal disease (persistent failure >3 mo) Table 529-1 -- PEDIATRIC-MODIFIED RIFLE (PRIFLE) CRITERIA