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Coronary artery disease among asymptomatic diabetic and non-diabetic patients undergoing coronary CT angiography
1. CORONARY ARTERY DISEASE AMONG ASYMPTOMATIC DIABETIC AND NONDIABETIC PATIENTS UNDERGOING CORONARY CT ANGIOGRAPHY Zeina AR, Blinder J, Rosenschein U, Zaid G , Barmeir E _______________________________________________________________________________ Zeina et al, Coronary Artery Disease 2008, 19:37–41
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4. The aim of this study was to determine the prevalence and severity of CAD and the plaque composition in asymptomatic diabetic patients undergoing coronary CT angiography (CCTA) _______________________________________________________________________________ Purpose Zeina et al, Coronary Artery Disease 2008, 19:37–41
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6. Table 1. Baseline characteristics of diabetic and non-diabetic patients. _______________________________________________________________________________ Zeina et al, Coronary Artery Disease 2008, 19:37–41 0.96 101 (35) 15 (36) Smoking, n (%) 0.34 152 (53) 19 (45) Hyperlipidemia, n (%) 0.17 138 (48) 25 (59) Hypertension, n (%) 0.19 126 (44) 14 (33) Family history, n (%) 0.17 213 (74) 38 (90) Male gender, n (%) 0.10 56 ± 9 58 ± 8 Age (years ± SD) (N= 286) (N= 42) P value Non-diabetic patients Diabetic patients
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9. Table 2. CCTA characteristics of the study population and comparison between diabetic and non-diabetic patients. * P value < 0.05 is considered significant. CCTA= coronary CT angiography _______________________________________________________________________________ Results Zeina et al, Coronary Artery Disease 2008, 19:37–41 0.1 1 (0.3%) 1 (2%) Three-vessel disease 0.3 2 (0.7%) 1 (2%) Two-vessel disease < 0.0001 16 (5.6%) 10 (24%) One-vessel disease < 0.0001 2.8 5.5 Segments with plaques/patient 0.07 141 (49%) 27 (64%) Non-obstructive CAD < 0.0001 19 (6.6%) 12 (29%) Obstructive CAD 0.006 211 (74%) 39 (93%) Coronary plaques < 0.0001 79.9 ± 16 370 ± 96 Total Agatston score (n= 286) (n= 42) P value * Non-diabetic patients Diabetic patients