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
2 of 26
 Blood loss of:
 > 500 mL during vaginal delivery
 > 1,000 mL following cesarean delivery
 Measurements are subjective and likely inaccurate
 Primary (early): within 24 hrs of delivery
 Secondary (late): from 24 hrs – 12 wks post-
delivery
Definition

3 of 26
 Defined clinically as excessive bleeding that makes the patient
symptomatic
 10% drop in hematocrit
 Signs/symptoms of blood loss
Objective Criteria

4 of 26
 One of the most common obstetrical emergencies
 Major cause of maternal morbidity
 One of the top 3 causes of direct maternal death in
both developing and developed countries
 Leading cause of admission to the ICU
 Incidence
 4% after vaginal delivery
 6.5% after C/S delivery
Why is it important?

5 of 26
Causes of PPH can be remembered as the 4 ‘Ts’
Tone Uterine atony
Trauma Injury to cervix, vagina, perineum
Tissue Retained placenta &/or membranes
Thrombin Clotting disorders
Etiology

6 of 26
 Call for help, ABCs
 O2 by mask initially
 2 x 14-gauge IV lines
 FBC & clotting studies
 Test for renal function & liver function tests
 Cross-match at least 6 units of blood
 IV fluid resuscitation
 Notify blood bank & consult hematologist
 Foley catheter into the bladder & fluid balance chart
 Blood transfusion asap, O- if not available
 Central venous pressure & arterial lines
 May need FFP, platelets & cryoprecipitate (consult hematologist)
 Eliminate the cause
Initial Management

7 of 26
 Most common cause of excessive PPH
 Risk Factors:
 Overworked: Rapid or prolonged labor (most common)
 Infected: Chorioamnionitis
 Relaxed: MgSO4, β-agonists, halothane
 Overdistended: Multiple pregnancies, macrosomia,
polyhydramnios
Uterine Atony (80%)

8 of 26
 Clinical Findings:
 A soft uterus (feels like dough) palpable above the
umbilicus.
 Management:
 Uterine massage
 Uterotonics (oxytocin, ergonovine, misoprostol, carboprost)
 Surgical: Uterine packing or compression balloon,
B-Lynch suture, sequential arterial ligation, selective arterial
embolization, hysterectomy
Uterine Atony (80%)
9 of 26
Bimanual Uterine Massage
10 of 26
Compression
Balloons
11 of 26B-Lynch Suture

12 of 26
 Risk Factors:
 Difficult delivery (shoulder dystocia, macrosomia)
 Instrumental delivery (forceps, vacuum extractor)
 Clinical Findings:
 Identifiable lacerations (cervix, vagina, perineum) in
the presence of a contracted uterus.
 Management:
 Surgical repair.
Genital Lacerations (15%)
13 of 26
Cervical Laceration Repair

14 of 26
 Risk Factors:
 Accessory placental lobe (most common)
 Abnormal trophoblastic uterine invasion
 Clinical Findings:
 Missing placental cotyledons in the presence of a
contracted uterus.
 Management:
 Manual removal or uterine curettage under US guidance.
Retained Placenta (5%)
15 of 26
Placenta
Fetal side
16 of 26
Placenta
Maternal side
17 of 26
Succenturiate Placental Lobe

18 of 26
Manual removal of placenta

19 of 26
Uterine curettage

20 of 26
 Risk Factors:
 Abruptio placenta (most common)
 Severe preeclampsia
 Amniotic fluid embolism
 Prolonged retention of a dead fetus
 Clinical Findings:
 Generalized oozing
 Bleeding from IV sites or lacerations in the presence of a
contracted uterus.
 Management:
 Removal of pregnancy tissues from the uterus
 Intensive care unit (ICU) support
 Selective blood-product replacement.
DIC (Rare)

21 of 26
 Risk Factors:
 Fundal placentation
 Excessive cord traction
 Previous uterine inversion.
 Clinical Findings:
 Beefy-appearing bleeding mass in the vagina and failure to
palpate the uterus abdominally.
 Management:
 Elevating the vaginal fornices and lifting the uterus back into
its normal anatomic position
 IV oxytocin.
Inverted Uterus (rare)

22 of 26
Progressive degrees of inversion

23 of 26
Manual replacement of uterine inversion

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Clinical Diagnosis Management
Uterus not palpable Inversion (rare) ↑ fornices, IV oxytocin
Uterus like dough Atony (80%) Uterine massage,
oxytocin, ergot, PG
F2α
Tears in vagina, cervix Laceration (15%) Suture & repair
Placenta incomplete Retained placenta (5%) Manual removal or
curettage
Diffuse oozing DIC (rare) Remove POC, ICU
care, blood products
Summary

25 of 26
Thank You!

26 of 26
1. Obstetrics by Ten Teachers, 19e - 2011
2. Williams Obstetrics, 24e - 2014
3. A Comprehensive Textbook of Postpartum
Hemorrhage, 2e - 2012
4. Step Up to Obstetrics & Gynecology – 2014
5. Obstetrics & Gynecology Lecture Notes – 2013
6. Postpartum hemorrhage on Wikipedia
(http://en.wikipedia.org/wiki/Postpartum_hemorrhage)
Sources

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Postpartum Hemorrhage

  • 2.  2 of 26  Blood loss of:  > 500 mL during vaginal delivery  > 1,000 mL following cesarean delivery  Measurements are subjective and likely inaccurate  Primary (early): within 24 hrs of delivery  Secondary (late): from 24 hrs – 12 wks post- delivery Definition
  • 3.  3 of 26  Defined clinically as excessive bleeding that makes the patient symptomatic  10% drop in hematocrit  Signs/symptoms of blood loss Objective Criteria
  • 4.  4 of 26  One of the most common obstetrical emergencies  Major cause of maternal morbidity  One of the top 3 causes of direct maternal death in both developing and developed countries  Leading cause of admission to the ICU  Incidence  4% after vaginal delivery  6.5% after C/S delivery Why is it important?
  • 5.  5 of 26 Causes of PPH can be remembered as the 4 ‘Ts’ Tone Uterine atony Trauma Injury to cervix, vagina, perineum Tissue Retained placenta &/or membranes Thrombin Clotting disorders Etiology
  • 6.  6 of 26  Call for help, ABCs  O2 by mask initially  2 x 14-gauge IV lines  FBC & clotting studies  Test for renal function & liver function tests  Cross-match at least 6 units of blood  IV fluid resuscitation  Notify blood bank & consult hematologist  Foley catheter into the bladder & fluid balance chart  Blood transfusion asap, O- if not available  Central venous pressure & arterial lines  May need FFP, platelets & cryoprecipitate (consult hematologist)  Eliminate the cause Initial Management
  • 7.  7 of 26  Most common cause of excessive PPH  Risk Factors:  Overworked: Rapid or prolonged labor (most common)  Infected: Chorioamnionitis  Relaxed: MgSO4, β-agonists, halothane  Overdistended: Multiple pregnancies, macrosomia, polyhydramnios Uterine Atony (80%)
  • 8.  8 of 26  Clinical Findings:  A soft uterus (feels like dough) palpable above the umbilicus.  Management:  Uterine massage  Uterotonics (oxytocin, ergonovine, misoprostol, carboprost)  Surgical: Uterine packing or compression balloon, B-Lynch suture, sequential arterial ligation, selective arterial embolization, hysterectomy Uterine Atony (80%)
  • 9. 9 of 26 Bimanual Uterine Massage
  • 11. 11 of 26B-Lynch Suture
  • 12.  12 of 26  Risk Factors:  Difficult delivery (shoulder dystocia, macrosomia)  Instrumental delivery (forceps, vacuum extractor)  Clinical Findings:  Identifiable lacerations (cervix, vagina, perineum) in the presence of a contracted uterus.  Management:  Surgical repair. Genital Lacerations (15%)
  • 13. 13 of 26 Cervical Laceration Repair
  • 14.  14 of 26  Risk Factors:  Accessory placental lobe (most common)  Abnormal trophoblastic uterine invasion  Clinical Findings:  Missing placental cotyledons in the presence of a contracted uterus.  Management:  Manual removal or uterine curettage under US guidance. Retained Placenta (5%)
  • 17. 17 of 26 Succenturiate Placental Lobe
  • 18.  18 of 26 Manual removal of placenta
  • 19.  19 of 26 Uterine curettage
  • 20.  20 of 26  Risk Factors:  Abruptio placenta (most common)  Severe preeclampsia  Amniotic fluid embolism  Prolonged retention of a dead fetus  Clinical Findings:  Generalized oozing  Bleeding from IV sites or lacerations in the presence of a contracted uterus.  Management:  Removal of pregnancy tissues from the uterus  Intensive care unit (ICU) support  Selective blood-product replacement. DIC (Rare)
  • 21.  21 of 26  Risk Factors:  Fundal placentation  Excessive cord traction  Previous uterine inversion.  Clinical Findings:  Beefy-appearing bleeding mass in the vagina and failure to palpate the uterus abdominally.  Management:  Elevating the vaginal fornices and lifting the uterus back into its normal anatomic position  IV oxytocin. Inverted Uterus (rare)
  • 22.  22 of 26 Progressive degrees of inversion
  • 23.  23 of 26 Manual replacement of uterine inversion
  • 24.  24 of 26 Clinical Diagnosis Management Uterus not palpable Inversion (rare) ↑ fornices, IV oxytocin Uterus like dough Atony (80%) Uterine massage, oxytocin, ergot, PG F2α Tears in vagina, cervix Laceration (15%) Suture & repair Placenta incomplete Retained placenta (5%) Manual removal or curettage Diffuse oozing DIC (rare) Remove POC, ICU care, blood products Summary
  • 26.  26 of 26 1. Obstetrics by Ten Teachers, 19e - 2011 2. Williams Obstetrics, 24e - 2014 3. A Comprehensive Textbook of Postpartum Hemorrhage, 2e - 2012 4. Step Up to Obstetrics & Gynecology – 2014 5. Obstetrics & Gynecology Lecture Notes – 2013 6. Postpartum hemorrhage on Wikipedia (http://en.wikipedia.org/wiki/Postpartum_hemorrhage) Sources