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Blood loss of:
> 500 mL during vaginal delivery
> 1,000 mL following cesarean delivery
Measurements are subjective and likely inaccurate
Primary (early): within 24 hrs of delivery
Secondary (late): from 24 hrs – 12 wks post-
delivery
Definition
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Defined clinically as excessive bleeding that makes the patient
symptomatic
10% drop in hematocrit
Signs/symptoms of blood loss
Objective Criteria
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One of the most common obstetrical emergencies
Major cause of maternal morbidity
One of the top 3 causes of direct maternal death in
both developing and developed countries
Leading cause of admission to the ICU
Incidence
4% after vaginal delivery
6.5% after C/S delivery
Why is it important?
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Causes of PPH can be remembered as the 4 ‘Ts’
Tone Uterine atony
Trauma Injury to cervix, vagina, perineum
Tissue Retained placenta &/or membranes
Thrombin Clotting disorders
Etiology
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Call for help, ABCs
O2 by mask initially
2 x 14-gauge IV lines
FBC & clotting studies
Test for renal function & liver function tests
Cross-match at least 6 units of blood
IV fluid resuscitation
Notify blood bank & consult hematologist
Foley catheter into the bladder & fluid balance chart
Blood transfusion asap, O- if not available
Central venous pressure & arterial lines
May need FFP, platelets & cryoprecipitate (consult hematologist)
Eliminate the cause
Initial Management
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Most common cause of excessive PPH
Risk Factors:
Overworked: Rapid or prolonged labor (most common)
Infected: Chorioamnionitis
Relaxed: MgSO4, β-agonists, halothane
Overdistended: Multiple pregnancies, macrosomia,
polyhydramnios
Uterine Atony (80%)
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Clinical Findings:
A soft uterus (feels like dough) palpable above the
umbilicus.
Management:
Uterine massage
Uterotonics (oxytocin, ergonovine, misoprostol, carboprost)
Surgical: Uterine packing or compression balloon,
B-Lynch suture, sequential arterial ligation, selective arterial
embolization, hysterectomy
Uterine Atony (80%)
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Risk Factors:
Abruptio placenta (most common)
Severe preeclampsia
Amniotic fluid embolism
Prolonged retention of a dead fetus
Clinical Findings:
Generalized oozing
Bleeding from IV sites or lacerations in the presence of a
contracted uterus.
Management:
Removal of pregnancy tissues from the uterus
Intensive care unit (ICU) support
Selective blood-product replacement.
DIC (Rare)
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Risk Factors:
Fundal placentation
Excessive cord traction
Previous uterine inversion.
Clinical Findings:
Beefy-appearing bleeding mass in the vagina and failure to
palpate the uterus abdominally.
Management:
Elevating the vaginal fornices and lifting the uterus back into
its normal anatomic position
IV oxytocin.
Inverted Uterus (rare)
26.
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1. Obstetrics by Ten Teachers, 19e - 2011
2. Williams Obstetrics, 24e - 2014
3. A Comprehensive Textbook of Postpartum
Hemorrhage, 2e - 2012
4. Step Up to Obstetrics & Gynecology – 2014
5. Obstetrics & Gynecology Lecture Notes – 2013
6. Postpartum hemorrhage on Wikipedia
(http://en.wikipedia.org/wiki/Postpartum_hemorrhage)
Sources