Folic Acid Synthesis Inhibitors

Folic Acid Synthesis Inhibitors ,[object Object]

Classification: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Folate Antagonists ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Folic Acid Synthesis in Bacteria Inhibited by SULFONAMIDES Dihydropteroate synthase

Effects of Sulfonamides ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Antibacterial Spectrum. (Sulfonamides) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

Mechanism Of Action of Sulfonamides ,[object Object],[object Object],Sulfonamides Dihydropteroate Synthetase Dihydropteroic Acid

Important Considerations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pharmacokinetics of Sulfonamides ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object]

Untoward reactions of sulfonamides ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

2. Disorder of the hematopoietic: ,[object Object],[object Object],[object Object],[object Object],[object Object]

3. Hypersensitivity reaction: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Indications of sulfonamides: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],3 – 6 weeks

[object Object],[object Object],[object Object],[object Object]

Some Sulfonamides used alone: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Contraindications of Sulfonamides ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Diaminopyrimidines ,[object Object],[object Object],[object Object],[object Object],[object Object]

Mechanism Of Action of trimethoprim Pteridine + PABA Dihydropteroic Acid Dihydrofolic acid Tetrahydrofolic Acid glutamate Blocked By Sulfonamides Blocked By Trimethoprim NADPH NADP

The Combinations ,[object Object],[object Object],[object Object]

Mechanism Of Action of Co-Trimoxazole Pteridine + PABA Dihydropteroic Acid Dihydrofolic acid Tetrahydrofolic Acid glutamate Blocked By Sulfamethoxazole Blocked By Trimethoprim NADPH NADP

Antibacterial Spectrum of Co-trimoxazole ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Adverse effects of Co-trimoxazole ,[object Object],[object Object],[object Object],[object Object],[object Object]

Therapeutic uses of Co-Trimoxazole. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Folic Acid Synthesis Inhibitors

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Folic Acid Synthesis Inhibitors