1) Hemoglobin is more efficient at transporting oxygen than suggested by its dissociation curve because the amount of oxygen it carries depends on both the partial pressure of oxygen and carbon dioxide. 2) At tissues with high carbon dioxide levels, hemoglobin has a lower affinity for oxygen and releases more oxygen, while at the lungs with low carbon dioxide it has a higher affinity and picks up more oxygen. 3) Fetal hemoglobin has a higher affinity for oxygen than adult hemoglobin due to its dissociation curve being shifted left, allowing it to more readily obtain oxygen from the mother's blood through the placenta.